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Chemistry World October 29, 2009 Phillip Broadwith |
Two metals are better than one UK chemists have developed reagents that can metallate ethers and ethene at room temperature without them disintegrating. |
Chemistry World April 12, 2012 Simon Hadlington |
Recruiting electrophiles for organic cross-coupling Chemists in the US have taken an unconventional approach to carbon cross-coupling and in doing so have potentially opened the door to the rapid and efficient synthesis of a wide range of organic compounds. |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World October 5, 2006 Mark Peplow |
Boron Shows Its Negative Side A molecule that hosts a negatively-charged boron atom could prove to be an exciting addition to the chemist's toolbox, according to researchers who have isolated the anion as its lithium salt. |
Chemistry World March 19, 2009 Manisha Lalloo |
Copper catalysts give meta aromatics UK Researchers have discovered that, simply by using a copper catalyst, they are able to perform tricky substitution reactions at a difficult position on benzene rings |
Chemistry World November 8, 2007 James Mitchell Crow |
First Mg(I) Complex Made Chemists have created the first stable magnesium(I) compounds, a breakthrough for a metal whose chemistry is ruled by the oxidation state. |
Chemistry World March 2, 2015 Andy Extance |
Chemists zinc up 'aromatic' metal cubes Researchers in China and the US have synthesized polyzinc clusters that have pushed back the boundaries of the kind of aromatic structures chemists can make. |
Chemistry World October 22, 2009 Simon Hadlington |
Carbenes catalyse metal-metal bonds in organometallics Chemists in the US have discovered a novel way to transform organometallic compounds so that new metal-metal bonds are created. |
Chemistry World March 22, 2012 Ross McLaren |
Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule. |
Chemistry World February 21, 2007 Tom Westgate |
Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules. |
Chemistry World April 26, 2007 Richard Van Noorden |
Hydrogen Busters go Synthetic Chemists have created a small molecule which mimics the way natural enzymes chew up hydrogen. The model should inspire designs for new catalysts that can break up hydrogen in fuel cells; or (running in reverse) help produce the fuel for a hydrogen economy. |
Chemistry World January 2, 2013 Derek Lowe |
Fear of the unknown My mental file drawer labelled 'Terrible Reagents I Have Known' is even larger than the one called 'Lunatics I Have Worked With and their Life-Threatening Ideas'. We organic chemists really do work with some terrible chemicals, and it's up to us to keep them from causing havoc. |
Reactive Reports Issue 62 |
Alumination at last! More powerful solid rocket fuel could be the product of research into a new class of compounds containing aluminum and hydrogen compounds, according to an international research team. |
Chemistry World November 27, 2009 Simon Hadlington |
A simple way to join an olefin to an arene Chemists in the US have developed a simple and effective way to carry out a key class of reaction in organic synthesis - the bolting an olefin to an aromatic ring. |
Chemistry World April 28, 2014 Simon Hadlington |
Elusive sigma aromaticity captured Chemists in the US have created a unique transition metal hydride in which the hydrogens form a five-membered aromatic ring, something that had been theorized, but until now never seen. |
Chemistry World June 1, 2012 Mike Sutton |
A reluctant chemist A century after Francois Auguste Victor Grignard's Nobel prize, organic chemists are still using the reagents he developed. |
Chemistry World August 2008 |
Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now? |
Chemistry World March 25, 2011 Simon Hadlington |
New synthesis for chiral anticancer compound The promising anticancer compound nutlin-3 is likely to become more widely available to researchers thanks to a new synthetic protocol developed by US chemists. |
Chemistry World September 30, 2009 Simon Haddlington |
Porous networks trap reactive intermediates Chemists in Japan have shown how it is possible to take sequential x-ray snapshots of chemical reactions taking place within molecular-sized 'reaction chambers', capturing the crystal structures of short-lived reactive intermediates. |
Chemistry World November 2010 |
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. |
Chemistry World November 25, 2014 James Urquhart |
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. |
Chemistry World August 2008 Paul Docherty |
Column: Totally Synthetic Impersonating nature isn't easy, and biomimetic syntheses are remarkable in two senses. |
Chemistry World March 20, 2007 Tom Westgate |
Is Your Lab Ready to go Veggie? In a recently published review article, Geoffrey Cordell demonstrates that the greengrocer's could be an unexpected goldmine of sustainable, cheap reagents that would benefit chemistry in developing countries. |
Chemistry World July 21, 2010 Lewis Brindley |
Selenium-based quinones show anticancer promise The new compounds have great potential for future cancer therapy, and early studies show similar activity to the well-known chemotherapy drug cisplatin, although a selenium-based therapy would cost a fraction of the price. |
Chemistry World April 25, 2014 Derek Lowe |
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. |
Chemistry World July 8, 2010 Phillip Broadwith |
Flattening carbon UK researchers have managed to synthesise a molecule with an almost planar four-coordinate carbon atom bonded to two lithium atoms and bulky organic ligands. |
Reactive Reports December 2006 David Bradley |
Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database. |
Chemistry World August 22, 2014 Derek Lowe |
Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today. |
Chemistry World November 7, 2013 Polly Wilson |
Hydrogen adopts alkali metal position For the first time, scientists have shown that hydrogen can stand in for alkali metals in typical alkali metal structures. |
Chemistry World February 27, 2009 Hayley Birch |
More data from mixtures via NMR Finnish scientists have developed a new technique for separating out the NMR spectra of compounds in a mixture. |
Chemistry World April 13, 2006 Jon Evans |
Chemists Bring Alien Molecule Down to Earth Chemists have recreated an alien molecule in the laboratory by synthesising a stable version of the carbene cyclopropenylidene. Cyclopropenylidene was first detected by radio astronomers in 1985, and is now the most abundant cyclic hydrocarbon observed in interstellar space. |
Chemistry World November 11, 2015 Aurora Walshe |
H 2-free route to actinide hydrides Scientists in the US have shown that phenylsilane is a safer and more convenient replacement for hydrogen gas when synthesizing uranium and thorium hydrides. |
Chemistry World February 14, 2008 Simon Hadlington |
Molecular Sponges Mop up Carbon Dioxide US researchers have created a range of new chemical 'sponges' that could be used to soak up carbon dioxide from power stations. |
Chemistry World June 2008 |
Column: In the pipeline The author, a medicinal chemist working on preclinical drug discovery, takes a look at the differences between chemists and biologists working on the same team. |
Chemistry World August 21, 2008 Fred Campbell |
Double bonding with silicon In a landmark for silicon chemistry, US researchers have reported the first stable silicon (0) compound to contain a silicon-silicon double bond. |
Chemistry World August 15, 2013 Caryl Richards |
First agostic isomers uncovered from two-tone crystals The discovery that two different colored crystals can form from the same molybdenum cation has signalled the first experimental evidence for agostic isomers -- or agostomers -- in organometallic complexes. |
Chemistry World February 27, 2013 Simon Hadlington |
Supercharging methanol for fuel cells Scientists in Germany and Italy have discovered a way to derive hydrogen gas from methanol at low temperatures and pressures using soluble ruthenium-based 'pincer' catalysts. |
Chemistry World August 2007 Derek Lowe |
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. |
Chemistry World June 1, 2012 Derek Lowe |
Peace, love and understanding You'd think that the chemists and biologists working in drug discovery would understand each other pretty well by now. You would be wrong about that. |
Chemistry World June 2008 Sarah Houlton |
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success |
Chemistry World November 14, 2011 Jon Cartwright |
Chemists claim metallic hydrogen creation first For over a century, scientists have said it should be possible to turn hydrogen into a metal. Now, a pair of chemists in Germany claim to have finally performed the feat, although others remain skeptical. |
Chemistry World July 27, 2009 Simon Hadlington |
Peer review by live blogging Blogging can immediately bring together expert opinion on a given topic. Poorly reviewed papers claiming novelty can be expected to be rapidly dissected in the blogosphere, as some chemists have found out. |
Chemistry World April 12, 2013 Melissae Fellet |
Elusive atmospheric intermediates reveal some secrets Scientists have found further evidence for the existence of an elusive intermediate implicated in chemical reactions that degrade atmospheric pollutants. |
Chemistry World January 3, 2012 Simon Hadlington |
One-pot synthesis creates anticancer candidates Researchers in Germany have developed a simple, rapid and high-yielding cascade synthesis of a collection of polycyclic compounds that resemble indole alkaloid natural products and which interfere with cell division. |
Chemistry World January 25, 2013 Derek Lowe |
Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers? |
Chemistry World February 13, 2011 Simon Hadlington |
First purely organic phosphor Scientists in the US have made a major advance in the development of novel light-emitting materials by designing the first purely organic phosphorescent compound. |
Chemistry World July 2, 2014 Victoria Richards |
Molecular brass Brass has been known to man since prehistoric times; now scientists in Germany have isolated the first molecular example of the copper -- zinc alloy. |
Technology Research News January 15, 2003 Eric Smalley |
Metal stores more hydrogen One reason the world isn't running on hydrogen fuel is that it's hard to store. Researchers from the National University of Singapore have made an accidental discovery that brings the promise of clean hydrogen energy a big step forward. |
Chemistry World May 8, 2015 Jennifer Newton |
Chemists snare 17-electron half-sandwich radical A team from Nanjing University in China has successfully synthesized and characterized the organometallic radical cation [(C 6Me 6)Cr(CO) 3] +. |
Chemistry World December 19, 2010 Simon Hadlington |
Novel route to key aromatics US chemists have found a new way to create aromatic compounds from straight chains of hydrocarbons by using an iridium-based catalyst. |