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Technology Research News October 20, 2004 Eric Smalley |
Wide laser makes simple tweezers Much of medical diagnostics and biomedical research involves trapping, manipulating and sorting individual cells and like-sized bits of matter. A recently demonstrated way of manipulating cells promises to be less expensive than laser tweezers. |
Chemistry World April 26, 2009 Simon Hadlington |
Glowing protein in 'animal photosynthesis' Scientists have discovered that a glowing protein found in some exotic marine animals and used widely as a 'marker' in molecular biology has another remarkable property |
Technology Research News March 26, 2003 |
Plastic coating makes chips biofriendly Electronics usually don't mix well with biological material. Sandia National Laboratories researchers have overcome the incompatibility with a microscopic laser designed to quickly measure and identify microorganisms and cell types without inhibiting biological processes. |
Chemistry World May 26, 2011 Russell Johnson |
Hunting elusive green fluorescent proteins After a 40 year hunt, scientists have tracked down the genes responsible for fluorescent proteins in Obelia medusa - a type of jellyfish. Knowledge of these genes could lead to new fluorescent protein tags for use in cell biology. |
Chemistry World October 15, 2008 Simon Hadlington |
Long-life light illuminates cells The new dye, based on platinum, will carry on emitting light long after any interfering 'autofluorescence' from naturally occurring molecules in the cell has fizzled out. |
Technology Research News December 1, 2004 Eric Smalley |
Pure Silicon Laser Debuts Researchers have made a prototype laser from silicon. The laser is tunable, meaning it can lase in a range of wavelengths, or colors, and it works at room temperature. |
Chemistry World July 3, 2015 Michaela Muehlberg |
Fluorescent protein spectrum shunted by single hydrogen bond Scientists in Denmark have found that a single hydrogen bond can have a drastic effect on the photophysical properties of molecular chromophores found in fluorescent proteins. |
Bio-IT World February 11, 2005 Kevin Davies |
In Living Color Researchers have developed a palette of fluorescent proteins to complement the green fluorescent protein (GFP), a stable of cell biology for a decade. |
Chemistry World November 2008 |
A glowing green Nobel The molecule that revolutionized and illuminated cell biology started with a jellyfish. Lewis Brindley tells the story of this year's Nobel prize for chemistry |
AboutSafety May 8, 2001 |
Laser Safety Guidelines for understanding the dangers of lasers and the importance of working with them safely... |
Bio-IT World July 15, 2003 Julia Boguslavsky |
'Fingerprinting' a Single Cell Single-cell proteomics is finally within reach, thanks to a professor of analytical chemistry. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. |
Chemistry World October 8, 2008 Lewis Brindley |
Green fluorescent protein takes Nobel Prize The protein, first isolated from a jellyfish, is now routinely used as a brightly glowing marker to track the positions and interactions of proteins in cells. |
Chemistry World March 6, 2006 Jon Evans |
Nanoprobes Light up Cellular Demolition Researchers have developed a method for detecting and imaging programmed cell death (apoptosis). The method, involving polymer nanoparticles, could be used to diagnose apoptosis-related diseases and inform drug development. |
Scientific American June 2008 Melinda Wenner |
How Cells Make Use of Random Biochemical Reactions New studies reveal how cells exploit biochemical randomness. |
Chemistry World October 23, 2014 |
The resolution revolution Super-resolution fluorescence microscopy earned three of its creators a Nobel prize this year. |
Chemistry World February 13, 2006 |
Nanoparticles Detect Cell Suicide Plans Researchers have developed a nanotechnological assay for detecting programmed cell death. The technique is effective in cell cultures, they report, and might eventually be used in humans. |
Chemistry World October 31, 2012 Ian Le Guillou |
A cell for a cell If you ever need to isolate a single bacterial cell, why not build it a prison cell? This is the approach that colleagues from Sandia National Laboratories, US, have taken. Using multi-photon lithography, they can construct four walls and a roof around a single cell in just over a minute. |
Wired November 24, 2008 Erin Biba |
Rocket Scientist's Laser Scalpel Targets Individual Cells Researcher Adela Ben-Yakar is developing a laser capable of vaporizing individual cells, one at a time. |
Technology Research News April 20, 2005 |
Trapped Cells Make Micromotors Researchers have showed that it is possible to make live Chlamydomonas reinhardtii cells rotate while pinned in a laser trap. The energy of a light beam can be used to manipulate and trap cells much like the way wind moves objects a larger scale. |
Bio-IT World July 2005 David M. Evans |
Cellular Imaging Takes Drug Discovery to New Heights The potential applications and ultimate value of high-content screening (HCS) and cellular image analysis are limited only by the imagination and expertise of the drug discovery groups using them to probe gene function and cell behavior. |
Chemistry World October 9, 2011 Simon Hadlington |
New probe throws light on cellular lipids Scientists in the US have developed a new sensor that can track and measure lipids in living cells. |
Chemistry World May 21, 2012 Simon Hadlington |
Rewritable DNA for digital data storage A rewritable memory storage module can form the basis of a digital memory system, scientists suggest, with the cell being able to 'record' transient changes in its internal chemistry. |
Reactive Reports September 2005 David Bradley |
When Good Turns Bad Prions, the protein-like pathogens at the heart of the fatal brain disorder CJD, so-called mad cow disease, and related diseases can rapidly "remodel" good proteins into bad, according to US scientists, who have demonstrated this for the first time in living cells. |
Chemistry World January 4, 2007 Henry Nicholls |
Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell. |
HHMI Bulletin May 2012 Nicole Kresge |
Locating a Genetic Glitch A team of 41 scientists led by HHMI investigator Louis Ptacek has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known protein that may be responsible for communication between neurons. |
Chemistry World October 31, 2010 Michael Gross |
Kiss of death for cancer cells Scientists have deciphered the surprising structure of the perforin pore, which delivers the 'kiss of death' to virus-infected cells and cancer cells in the body. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
Chemistry World October 2, 2012 Fiona McKenzie |
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. |
Chemistry World July 28, 2009 Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
Chemistry World February 9, 2009 Phillip Broadwith |
Molecular thermometer takes cell temperature A fluorescent polymer that can accurately measure the temperature inside living cells has been invented by researchers in Japan. |
Bio-IT World January 21, 2005 Robert M. Frederickson |
High-Throughput Science Although genomic assays led the charge toward high-throughput science, new detection systems and formats are enabling the application of high-throughput techniques to proteins and cells. |
Bio-IT World September 11, 2003 Julia Boguslavsky |
Cellular Screening in Sync No longer just a 'good idea,' high-content cellular screening is making an impact in target and lead selection. |
Technology Research News February 9, 2005 |
All-silicon chip laser demoed Researchers from Intel have moved a step forward in the push to meld lasers and silicon chips, which could eventually be used in portable biological and chemical sensors, to amplify communications signals, and to convert light to different wavelengths. |
Bio-IT World December 15, 2003 Malorye A. Branca |
Scenes from a Cell Breakthroughs are making cell-based screening faster, easier, more powerful. |
Chemistry World March 5, 2007 Victoria Gill |
Protein Stops HIV Infection in its Tracks Researchers have identified a protein that might help explain why promising microbicide gels are yet to prove effective against HIV transmission. |
Chemistry World August 15, 2007 John Bonner |
Chemists Claim Biological Alchemy South Korean chemists say they have turned muscle cells from the sole of a human foot into something akin to stem cells, using a simple molecule called neurodazine. |
HHMI Bulletin Aug 2011 Cassandra Willyard |
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. |
Chemistry World September 25, 2009 Simon Hadlington |
New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging. |
HHMI Bulletin May 2010 Sarah C.P. Williams |
Lab-Grown Liver New cell culture system solves problem of growing liver cells. |
Technology Research News June 1, 2005 |
Lasers Built Into Fiber-Optics Researchers have crossed a gas-filled fiber optic laser with ordinary fiber optics to make a Raman laser and a frequency stabilizer -- devices that provide precise control of laser beams. |
AskMen.com Dave Golokhov |
Balding And Stem Cells While many men just write baldness off as a hereditary hurdle, a new study has offered a thread of hope. |
Chemistry World October 8, 2014 |
Super-resolution light microscopy wins chemistry Nobel The 2014 chemistry Nobel prize has been given to three pioneers of biomedical imaging, whose work has enabled nanoscale features within cells to be captured in exquisite detail. |
Chemistry World May 5, 2011 Simon Hadlington |
Revolutionary new single-cell labelling method Researchers in the US and Canada have combined mass spectrometry with a technique called flow cytometry to follow dozens of biochemical markers on individual cells simultaneously. |
PC Magazine May 18, 2005 Neil J. Rubenking |
Convert Blank Cells to Zeros in Excel In Excel, is there any way to select a range of cells and tell Excel to fill the blank cells with the value zero? |
Smithsonian March 2004 |
Signal Discovery? A Los Angeles scientist says living cells may make distinct sounds, which might someday help doctors "hear" diseases |
Chemistry World November 25, 2013 Carla Pegoraro |
Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology. |
Chemistry World April 20, 2012 Jennifer Newton |
Nanocrystal probes mimic viruses to gain entry into cells Colloidal polymer vectors loaded with nanocrystal probes enter cells in the same way as a virus and can be used to track cells for therapies such as those based on stem cells |
IEEE Spectrum August 2006 Schoenbach et al. |
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. |