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Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. |
Chemistry World March 21, 2013 Neil Withers |
Norman Dovichi: Singing the praises of the unsung hero At this year's Pittcon, Norman Dovichi of Notre Dame University in Indiana, US, received the 2012 Robert Boyle Prize for Analytical Science from the RSC. The prize is awarded for outstanding contributions to analytical science. |
Chemistry World October 9, 2011 Simon Hadlington |
New probe throws light on cellular lipids Scientists in the US have developed a new sensor that can track and measure lipids in living cells. |
Bio-IT World August 13, 2002 Malorye Branca |
The Proteomics Odyssey Efforts to map the constellation of protein interactions in humans gather momentum as companies vie to provide tools to capitalize on the potential of proteomics. But can proteomics prevail where some feel genomics has failed? |
Industrial Physicist Aug/Sep 2003 Ineke Malsch |
Protein research calls for advanced instruments The science of protein interactions is becoming a major tool in biomedical and drug development research. Carrying out and advancing such studies more efficiently and effectively, however, will require new, cutting-edge instrumentation. |
HHMI Bulletin Aug 2011 Janelle Weaver |
Leading a Double Life with CSF Lucky for us, the organs in our bodies come with a self-repair kit. Though regularly bombarded by harmful bacteria, more often than not they manage to heal themselves. How this happens has puzzled scientists, but now there may be some answers. |
HHMI Bulletin Aug 2011 Cassandra Willyard |
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. |
Bio-IT World April 16, 2004 Robert Frederickson |
Trial Separations Protein separation through the digital ProteomeChip microchip takes merely minutes, resulting in significantly increased productivity. |
Chemistry World May 5, 2011 Simon Hadlington |
Revolutionary new single-cell labelling method Researchers in the US and Canada have combined mass spectrometry with a technique called flow cytometry to follow dozens of biochemical markers on individual cells simultaneously. |
Chemistry World January 4, 2007 Henry Nicholls |
Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell. |
Chemistry World August 4, 2011 Sarah Houlton |
Targeting DNA Packaging to Treat Leukaemia Scientists in the US have found a new drug target that could be important in treating acute myeloid leukaemia. |
IEEE Spectrum August 2006 Schoenbach et al. |
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. |
Chemistry World May 17, 2006 Bea Perks |
Biochemists Reveal Hidden Drug Effects Researchers have identified unexpected drug activities by probing biochemical pathways inside living cells. |
HHMI Bulletin Aug 2010 Sarah C.P. Williams |
Fruit Fly Cells Don't All Know What Sex They Are HHMI scientists have now found that many cells in male and female fruit flies not only look the same, they are more identical at a molecular level than was previously thought. |
HHMI Bulletin Aug 2010 Richard Saltus |
Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch. |
Chemistry World December 18, 2012 Jennifer Newton |
Technique to measure chemotherapy effectiveness A technique to measure how effective chemotherapy is by studying the physical changes that occur in human cells has been developed by US scientists. |
Scientific American June 2008 Melinda Wenner |
How Cells Make Use of Random Biochemical Reactions New studies reveal how cells exploit biochemical randomness. |
Chemistry World September 17, 2012 Jennifer Newton |
Seeing cells under stress An analytical platform that imposes controlled mechanical strain onto live cells while monitoring changes in cell morphology and molecular signalling has been developed by scientists in Germany. |
Chemistry World March 29, 2009 Lewis Brindley |
Gene gels pump out proteins Gels made with genes incorporated into the structure could soon make protein production cheaper and easier, according to researchers in the US. |
Chemistry World June 13, 2011 Laura Howes |
Cells turned into living lasers with fluorescent protein With a little help from a fluorescent protein, mammalian cells have been transformed into living lasers. This discovery could help improve imaging of living cells, enabling researchers to explore what's going on inside. |
Chemistry World February 2012 |
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball |
HHMI Bulletin Aug 2011 Sarah C.P. Williams |
The Goldilocks of Cells Too much or too little cell death can lead to disease. Scientists are learning how to find the range that's just right. |
Chemistry World May 21, 2012 Simon Hadlington |
Rewritable DNA for digital data storage A rewritable memory storage module can form the basis of a digital memory system, scientists suggest, with the cell being able to 'record' transient changes in its internal chemistry. |
Chemistry World November 25, 2013 Carla Pegoraro |
Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology. |
HHMI Bulletin Winter 2013 Amber Dance |
A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery. |
Chemistry World April 2010 |
Column: The crucible We are getting better at manipulating cells to grow into the tissues we need. Chemical factors are key, says Philip Ball |
Bio-IT World April 15, 2003 Robert M. Frederickson |
Protein Chemistry Surfaces Protein chips seek to do for protein expression profiling what DNA chips did for RNA expression. |
HHMI Bulletin February 2012 Sarah C. P. Williams |
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
HHMI Bulletin May 2012 John Roach |
Tiny Breathing Plant Mouths Keiko Torii was drawn from an interest in cancer research to a career in plant biology, but keeps her eyes open for relevance in both areas. |
Industrial Physicist Jennifer Ouellette |
Bioinformatics moves into the mainstream An explosion of data is being tamed with new systems |
Chemistry World February 9, 2009 Phillip Broadwith |
Molecular thermometer takes cell temperature A fluorescent polymer that can accurately measure the temperature inside living cells has been invented by researchers in Japan. |
HHMI Bulletin Winter 2013 Sarah C.P. Williams |
One Foot in Front of the Other In every type of living cell, materials jet around in a similar variety of manners. The way cellular cargo travels depends on its size, where it's headed, how quickly it must arrive, and how much energy is available. |
HHMI Bulletin February 2012 Sarah C.P. Williams |
The Twists and Turns of Immunity Fred Alt has built a career making sense of the immune system -- specifically, the diverse antibodies that fight off invading molecules, from viruses to cancer cells to pollen. |
Chemistry World April 26, 2009 Simon Hadlington |
Glowing protein in 'animal photosynthesis' Scientists have discovered that a glowing protein found in some exotic marine animals and used widely as a 'marker' in molecular biology has another remarkable property |
Chemistry World August 2, 2011 Kate McAlpine |
Hacking into chemical cell phone calls US researchers have made a nanodevice that can eavesdrop on a cell's mutterings, and they say it could be adapted to listen in on conversations between cells. |
Chemistry World October 31, 2012 Ian Le Guillou |
A cell for a cell If you ever need to isolate a single bacterial cell, why not build it a prison cell? This is the approach that colleagues from Sandia National Laboratories, US, have taken. Using multi-photon lithography, they can construct four walls and a roof around a single cell in just over a minute. |
Chemistry World January 13, 2010 Simon Hadlington |
Click chemistry reveals sugar synthesis in live animals US researchers have used 'click chemistry' to attach chemical tags to complex sugar molecules in the cells of live mice, allowing the synthesis of the sugars - glycans - within the cells to be tracked. |
HHMI Bulletin May 2010 Robert Tjian |
Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens. |
Wired August 2003 Jennifer Kahn |
The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine. |
Chemistry World October 2, 2012 Fiona McKenzie |
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. |
Chemistry World May 26, 2011 Russell Johnson |
Hunting elusive green fluorescent proteins After a 40 year hunt, scientists have tracked down the genes responsible for fluorescent proteins in Obelia medusa - a type of jellyfish. Knowledge of these genes could lead to new fluorescent protein tags for use in cell biology. |
Bio-IT World September 11, 2003 Mark D. Uehling |
Fishing Chips The next generation of protein microarrays from the likes of Protometrix and Molecular Staging may threaten the early leads of Biacore and Ciphergen -- and work so well that drug companies won't want them. |
HHMI Bulletin Spring 2013 Sarah C.P. Williams |
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. |
Chemistry World May 12, 2014 David Bradley |
Elemental discoveries at the cellular level A combination of two high-power analytical techniques -- synchrotron radiation microscopy and atomic force microscopy -- has allowed Italy scientists to map vital elements in a single cancer cell. |
Chemistry World May 7, 2014 Emma Stoye |
Bacterium survives unnatural DNA transplant The first organism that can grow and replicate with an unnatural base pair in its DNA -- giving the cell six nucleotides instead of the usual four -- has been created by scientists in the US. |
Bio-IT World August 15, 2005 Robert M. Frederickson |
What's 'Post' About Postgenomic? Bioinformatics tools can help organize and study genomic sequences that were discovered in the '90s. The tools help with tasks like analyzing gene expression, predicting protein structure and function, and establishing networks of interacting protein in cells. |
Managed Care November 2003 Thomas Morrow |
Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings. |