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Chemistry World May 26, 2011 Russell Johnson |
Hunting elusive green fluorescent proteins After a 40 year hunt, scientists have tracked down the genes responsible for fluorescent proteins in Obelia medusa - a type of jellyfish. Knowledge of these genes could lead to new fluorescent protein tags for use in cell biology. |
Chemistry World November 2008 |
A glowing green Nobel The molecule that revolutionized and illuminated cell biology started with a jellyfish. Lewis Brindley tells the story of this year's Nobel prize for chemistry |
Chemistry World June 13, 2011 Laura Howes |
Cells turned into living lasers with fluorescent protein With a little help from a fluorescent protein, mammalian cells have been transformed into living lasers. This discovery could help improve imaging of living cells, enabling researchers to explore what's going on inside. |
Chemistry World |
Fishing for Chemical Answers to Biological Questions James K. Chen talks about chemical biology, his love for the outdoors and fly fishing. |
HHMI Bulletin Winter 2013 Sarah C.P. Williams |
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. |
Chemistry World August 17, 2011 Josh Howgego |
Worms Modified to Express Unnatural Amino Acids Unnatural amino acids have been expressed for the first time in complex multicellular organisms. Researchers hope this will open up new ways to track biochemical processes and disease pathways. |
Chemistry World January 4, 2007 Henry Nicholls |
Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell. |
Bio-IT World February 11, 2005 Kevin Davies |
In Living Color Researchers have developed a palette of fluorescent proteins to complement the green fluorescent protein (GFP), a stable of cell biology for a decade. |
Chemistry World July 3, 2015 Michaela Muehlberg |
Fluorescent protein spectrum shunted by single hydrogen bond Scientists in Denmark have found that a single hydrogen bond can have a drastic effect on the photophysical properties of molecular chromophores found in fluorescent proteins. |
HHMI Bulletin Nov 2011 Sarah C. P. Williams |
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
Chemistry World June 25, 2012 Simon Hadlington |
Bloody Solution to Electrochemical DNA Sensors US researchers have discovered a way to significantly improve the sensitivity of DNA-based electrochemical sensors by incorporating an inexpensive, robust and stable protein into the system - haemoglobin. |
Chemistry World July 6, 2012 |
Protein power Tom Muir, professor of chemistry and molecular biology, Princeton University, US, is an expert in protein engineering and its application to studying cellular signalling networks. |
Chemistry World October 8, 2008 Lewis Brindley |
Green fluorescent protein takes Nobel Prize The protein, first isolated from a jellyfish, is now routinely used as a brightly glowing marker to track the positions and interactions of proteins in cells. |
Bio-IT World June 12, 2002 Mark D. Uehling |
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? |
Chemistry World October 9, 2011 Simon Hadlington |
New probe throws light on cellular lipids Scientists in the US have developed a new sensor that can track and measure lipids in living cells. |
Chemistry World September 29, 2010 Hayley Birch |
Protein folding: knotted or not A new study may help scientists unravel the complex problem of protein folding. The study suggests knotted proteins, which present a particular challenge to folding experts, could be untied with a couple of well-targeted tugs. |
Chemistry World June 7, 2012 Simon Hadlington |
Rethinking redox chemistry Metal oxide redox chemistry may be due a big re-think following new research by US scientists. It seems that it is not solely electrons that are being shunted about. In many, possibly most, cases a proton also comes along for the ride. |
Chemistry World November 11, 2009 James Urquhart |
Structural snapshots of complex molecules US researchers have pioneered a new spectroscopy technique to uncover the precise sequence of atomic movements and structural changes that occur during complex chemical transformations. |
Popular Mechanics April 15, 2009 Erin McCarthy |
Is Fringe's Genetic Monster Possible? Unlike the monster on Fringe, altered animals typically have only a single gene difference from non-altered animals -- but they can look different. |
Chemistry World February 2012 |
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball |
Chemistry World September 14, 2011 Laura Howes |
Aspirin Still Has Some Secrets Left to Give up The overlooked stereoelectric effect in aspirin makes the molecule less polar, which may improve the drug's bioavailability. |
Chemistry World October 2, 2012 Fiona McKenzie |
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. |
Chemistry World December 12, 2011 Simon Hadlington |
Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity. |
Bio-IT World July 15, 2003 Julia Boguslavsky |
'Fingerprinting' a Single Cell Single-cell proteomics is finally within reach, thanks to a professor of analytical chemistry. |
Chemistry World February 25, 2015 Dannielle Whittaker |
Computational tool leaves electrides with nowhere to hide Scientists in Spain have proven the existence of gas-phase electride materials through a computational method with the ability to distinguish electrides from similar ionic compounds. |
Chemistry World October 16, 2014 Simon Hadlington |
Helium happily shares electrons to create dianions Helium invariably sits with its arms tightly folded and refuses to participate in chemistry, but turns out to be surprisingly generous when it is in the right environment, willing to donate not just one but two electrons to neighboring species. |
Chemistry World September 4, 2013 Mark Peplow |
Synthetic biology is bursting with life The field encompasses a vast array of research themes, from creating artificial life to engineering microbes to produce medicines or fuels. Through it all, though, runs a rich seam of chemistry. |
Chemistry World August 24, 2009 Phillip Broadwith |
'Chemical nose' sensor sniffs blood protein profile US scientists have developed a sensor system for profiling the protein content of human blood serum without needing individual receptors for each separate protein. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. |
HHMI Bulletin Spring 2013 Nicole Kresge |
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. |
HHMI Bulletin Winter 2013 Amber Dance |
A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery. |
Chemistry World March 7, 2010 Simon Hadlington |
Solvated electron mystery solved Researchers have answered a riddle that has been puzzling scientists for decades: why is it that electrons in an aqueous environment appear to exist in two distinct states |
Chemistry World August 29, 2014 Simon Hadlington |
Rigid molecular wires make electrons fly Researchers in Germany and Japan have shown that a new type of organic molecular wire -- which is flat and rigid -- can transfer electrons at more than 800 times the speed of its conventional, flexible counterpart. |
Chemistry World September 13, 2012 Andy Merritt |
Chemical biology comes of age Historically strongest in the US, chemical biology has become increasingly important worldwide, but for many years researchers at the chemistry -- biology interface have struggled to establish their discipline |
Chemistry World February 3, 2010 Simon Hadlington |
New 'hook' for reversibly binding molecules to proteins UK chemists have found a simple new 'hook' that allows molecules to be attached to proteins and later removed, something that is currently difficult to achieve. |
HHMI Bulletin Winter 2013 Nicole Kresge |
A Structural Revolution Over the years, scientists and artists have used an assortment of techniques to showcase molecular structure. |
Chemistry World June 9, 2010 Jon Cartwright |
Laser tracks electrons in molecules The breakthrough suggests that attosecond lasers will soon enable scientists to address problems in chemistry and biology, which until now were too complex for attosecond science. |
Chemistry World June 14, 2011 |
A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR. |
Bio-IT World September 11, 2003 Mark D. Uehling |
Fishing Chips The next generation of protein microarrays from the likes of Protometrix and Molecular Staging may threaten the early leads of Biacore and Ciphergen -- and work so well that drug companies won't want them. |
Bio-IT World August 15, 2005 Robert M. Frederickson |
What's 'Post' About Postgenomic? Bioinformatics tools can help organize and study genomic sequences that were discovered in the '90s. The tools help with tasks like analyzing gene expression, predicting protein structure and function, and establishing networks of interacting protein in cells. |
Chemistry World April 27, 2006 |
`Sticky Trees' Glue Molecules to Proteins Researchers have developed a chemical glue that binds molecules to proteins without compromising protein function. The method could be used to modify a wide range of proteins for a variety of purposes, such as in the development of new protein-based therapies. |
Chemistry World November 21, 2007 Tom Westgate |
Proteins Protect Plants From Sunburn A team of European scientists have revealed the molecular mechanism that allows plants to protect themselves from strong sunlight. |
Chemistry World August 26, 2008 Fred Campbell |
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. |
Chemistry World June 17, 2013 Emma Stoye |
First vertebrate fluorescent protein discovered A protein from Unagi eels is the latest addition to the fluorescent protein paintbox, and the first to come from a vertebrate. |
Chemistry World October 24, 2008 Hayley Birch |
Proteins swap partners UK researchers have discovered that proteins which use metal cofactors can be surprisingly promiscuous metal binders, happily taking up the 'wrong' metal. |
Chemistry World September 19, 2008 John Bonner |
Filling the antibiotic gap Resistance to currently available antibacterial drugs is causing growing concern among doctors who find themselves unable to treat common infections |
Chemistry World December 23, 2015 |
Bones of contention Can protein in dinosaur bones survive for millions of years? Rachel Brazil explores the evidence. |
Chemistry World January 9, 2013 Laura Howes |
Antifreeze protein's watery dance Most animals left in -30 C temperatures wouldn't last very long. Not only would they get hypothermia, but the water in their bodies would start to freeze. Some animals and plants, however, use antifreeze proteins to keep ice at bay. |
HHMI Bulletin February 2011 Michele Solis |
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. |