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Chemistry World October 16, 2006 Michael Gross	Brief Encounter Observing fleeting interactions between molecules in solution requires extremely sophisticated methods. NMR spectroscopists have now developed tools that let them watch the transient encounter between two proteins before a well-defined complex is formed.
Chemistry World November 23, 2006 Simon Hadlington	Unfolding Peptide Watched in Real Time Researchers have observed a peptide molecule changing shape in real time. The ultrafast process was monitored using a technique called transient two-dimensional infrared spectroscopy.
Bio-IT World May 2006 Robert M. Frederickson	A New (Bio)Spin on NMR Applications Bruker BioSpin recently announced several introductions to improve throughput, sensitivity, and versatility of its systems for nuclear magnetic resonance applications starting with the SampleJet, a robotics system for high-throughput transfers of NMR sample tubes into the NMR spectrometer.
Chemistry World September 25, 2009 Simon Hadlington	New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging.
Technology Research News March 24, 2004	DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein.
Reactive Reports Issue 51 David Bradley	Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique.
Chemistry World August 26, 2008 Fred Campbell	High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester.
Chemistry World April 27, 2006	`Sticky Trees' Glue Molecules to Proteins Researchers have developed a chemical glue that binds molecules to proteins without compromising protein function. The method could be used to modify a wide range of proteins for a variety of purposes, such as in the development of new protein-based therapies.
Chemistry World October 2, 2012 Fiona McKenzie	Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells.
Chemistry World August 24, 2009 Phillip Broadwith	'Chemical nose' sensor sniffs blood protein profile US scientists have developed a sensor system for profiling the protein content of human blood serum without needing individual receptors for each separate protein.
Chemistry World May 5, 2009 Phillip Broadwith	Don't FRET over broken polymers Fluorescent proteins could one day help identify microscopic cracks and damage in polymer materials, allowing them to be monitored to prevent failure in load-bearing applications such as in aerospace and biomedical devices.
Chemistry World May 2, 2007 Michael Gross	Protein Printboard Chemists in the Netherlands have created nanoscale structures that can immobilize proteins with exquisite control over specificity, strength and orientation.
Chemistry World July 6, 2007 Michael Gross	Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail.
Chemistry World August 30, 2006 Tom Westgate	Lasers Shed Light on Magnetic Resonance A new way of measuring nuclear magnetic resonance (NMR) in liquid samples could have implications across spectroscopy and imaging, report researchers.
Chemistry World October 26, 2007 Richard Van Noorden	Proton NMR Spots Shape-Shifting Tablets UK scientists have extended the bounds of solid-state NMR to quickly solve a problem plaguing the pharmaceutical industry: how to spot unwanted crystal packing forms in a drug tablet.
Chemistry World January 19, 2011 Jon Cartwright	Modified protein binders give shortcut to drugs The method, which involves attaching polypeptides to the binders, could help reduce the work required to develop protein binders into safer drugs.
Chemistry World June 25, 2013 Michael Gross	A foaming protein from the horse's mouth Researchers in the UK have solved the structure of this protein, yielding tantalizing hints to a novel kind of surface activity and to evolutionary connections to other examples.
Chemistry World January 4, 2007 Henry Nicholls	Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell.
Chemistry World January 9, 2013 Laura Howes	Antifreeze protein's watery dance Most animals left in -30 C temperatures wouldn't last very long. Not only would they get hypothermia, but the water in their bodies would start to freeze. Some animals and plants, however, use antifreeze proteins to keep ice at bay.
Bio-IT World June 12, 2002 Mark D. Uehling	Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts?
Chemistry World May 17, 2012 David Bradley	Plutonium in a Spin Spectroscopists have finally pinned down the nuclear magnetic resonance spectrum of plutonium-239. The finding might point the way to improved approaches to the long-term storage of nuclear waste.
Chemistry World October 8, 2008 Sarah Houlton	Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures.
Technology Research News September 24, 2003 Kimberly Patch	Heated plastic holds proteins One important task for biochips is sorting proteins, but it's tricky business getting protein molecules to be where you want them and stay away from where you don't. A tiny, plastic-coated hot plate allows scientists to trap and release proteins on command.
Chemistry World December 12, 2011 Simon Hadlington	Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity.
HHMI Bulletin Feb 2011	DNA Curtains How proteins behave in such a crash test gives scientists data about their structural integrity, how they attach to DNA, and how they behave in a cell.
Chemistry World April 2, 2009 Ned Stafford	Fluorescent probes take screening to next level Researchers have developed a new high-throughput screening technique that could shed light on the biochemical activities of numerous proteins about which little is currently known.
Technology Research News January 14, 2004	Wet biochip preserves proteins Researchers from Kyushu University in Japan have produced a hydrogel material that makes it possible for proteins to survive aboard labs-on-a-chip.
Chemistry World January 30, 2013 Philip Robinson	NMR with a light touch Interactions between NMR-active nuclei in a sample and laser light could lead to a new, simpler form of NMR.
Chemistry World March 6, 2007 Michael Gross	Nature's Supramolecular Chemistry Researchers studying a bacterial molybdenum-storage protein have teamed up with inorganic chemists to resolve the structure of the storage protein's central cavity.
Chemistry World June 6, 2010 Philip Ball	Blood-like liquid protein formed A liquid form of the oxygen-binding protein myoglobin retains its biological function even though it seems virtually water-free, researchers have found.
Technology Research News June 18, 2003	Protein traps nanoparticles Researchers from the University of Tokyo in Japan have adapted a tubular bacterial protein for technological applications by coaxing it to combine with individual luminescent semiconductor nanoparticles.
Chemistry World May 5, 2011 Simon Hadlington	Revolutionary new single-cell labelling method Researchers in the US and Canada have combined mass spectrometry with a technique called flow cytometry to follow dozens of biochemical markers on individual cells simultaneously.
Chemistry World March 29, 2009 Lewis Brindley	Gene gels pump out proteins Gels made with genes incorporated into the structure could soon make protein production cheaper and easier, according to researchers in the US.
Industrial Physicist Aug/Sep 2003 Ineke Malsch	Protein research calls for advanced instruments The science of protein interactions is becoming a major tool in biomedical and drug development research. Carrying out and advancing such studies more efficiently and effectively, however, will require new, cutting-edge instrumentation.
Chemistry World January 5, 2007 Victoria Gill	PEG Makes Cheaper Drugs for Developing Countries UK and Indian scientists have embarked on a collaboration to develop a new protein-based treatment for hepatitis C, which they say will provide an affordable drug urgently needed in countries where resources are limited.
Chemistry World September 17, 2012 Ian Le Guillou	Raising the curtain on single-stranded DNA Scientists have created microfluidic devices containing single-stranded DNA 'curtains' for the first time, allowing scientists to study its interactions with proteins in real time.
Chemistry World March 23, 2012 Michael Gross	Molecular chaperones caught on film Researchers have combined thousands of snapshots of the barrel-shaped protein GroEL to create a series of films that follow its movement and binding events.
Chemistry World November 25, 2009 Simon Hadlington	Virus shells traps multiple proteins Scientists in The Netherlands have devised a way to pack large numbers of proteins into the empty shell of a virus.
Chemistry World June 24, 2011 Yuandi Li	An NMR machine in a fume hood Scientists in Germany have demonstrated a portable nuclear magnetic resonance spectrometer that's small enough to be placed in a fume cupboard to monitor the progress of a reaction in situ.
Chemistry World September 29, 2010 Hayley Birch	Protein folding: knotted or not A new study may help scientists unravel the complex problem of protein folding. The study suggests knotted proteins, which present a particular challenge to folding experts, could be untied with a couple of well-targeted tugs.
Chemistry World January 9, 2014	Spinning into focus NMR is used by big industry, and scientists in pharmaceutical companies, for example, have appreciated the benefits of NMR spectroscopy for years. It reveals the structure of molecules in a sample, providing more information than some other analytical techniques.
Chemistry World June 1, 2012 Simon Hadlington	Protein architecture with atomic precision Researchers have made a key breakthrough in designing and building geometrically defined nanostructures from proteins with unprecedented accuracy.
Chemistry World January 21, 2011 David Barden	Close encounter makes modifying proteins easy Chemists in the US have now developed a powerful strategy for selectively modifying the side-chains of proteins, which they hope will enable the creation of new tools to investigate protein interactions involved in human diseases.
Chemistry World August 17, 2011 Jon Cartwright	Plasma Treatment to Use Patient's Proteins to Improve Medical Device Biocompatibility Researchers have developed a plasma treatment that can make any medical device biocompatible by sticking a patient's own proteins to it.
Chemistry World February 27, 2009 Hayley Birch	More data from mixtures via NMR Finnish scientists have developed a new technique for separating out the NMR spectra of compounds in a mixture.
Reactive Reports Issue 75 David Bradley	Chasing Down Mad Cows Researchers in Europe have tracked down the molecular anchor that hooks errant and infectious prions leading to mad cow disease in sheep.
Chemistry World April 30, 2007 Victoria Gill	Amyloid Protein Seen to Zip Together Amyloid proteins' long, complicated structure makes them tricky to study, but U.S. researchers have found that they share a common feature that could provide a drug target for an array of incurable conditions.
HHMI Bulletin February 2012 Sarah C. P. Williams	Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors.
Bio-IT World April 15, 2003 Robert M. Frederickson	Protein Chemistry Surfaces Protein chips seek to do for protein expression profiling what DNA chips did for RNA expression.
Chemistry World June 2009 Michael Gross	Bubble-wrapped frogs Tropical frogs create remarkable protein foams to protect their spawn. Exploration of the underlying chemistry has only just begun