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Chemistry World December 12, 2011 Simon Hadlington |
Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity. |
Chemistry World June 14, 2011 |
A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR. |
Chemistry World September 17, 2012 Ian Le Guillou |
Raising the curtain on single-stranded DNA Scientists have created microfluidic devices containing single-stranded DNA 'curtains' for the first time, allowing scientists to study its interactions with proteins in real time. |
Chemistry World July 31, 2012 David Bradley |
Hydrogels can release drugs one at a time A hydrogel that can be programmed to release different protein drugs one after the other rather than all at once could simplify the delivery of complex therapeutic regimens for various diseases. |
Chemistry World January 19, 2011 Jon Cartwright |
Modified protein binders give shortcut to drugs The method, which involves attaching polypeptides to the binders, could help reduce the work required to develop protein binders into safer drugs. |
Bio-IT World April 15, 2003 Robert M. Frederickson |
Protein Chemistry Surfaces Protein chips seek to do for protein expression profiling what DNA chips did for RNA expression. |
Bio-IT World September 11, 2003 Mark D. Uehling |
Fishing Chips The next generation of protein microarrays from the likes of Protometrix and Molecular Staging may threaten the early leads of Biacore and Ciphergen -- and work so well that drug companies won't want them. |
Chemistry World December 17, 2010 James Mitchell Crow |
Drug delivery: from needles to nanorods? Gold nanorods warmed by beams of infrared light could be the ideal way to deliver drugs through the skin, researchers in Japan have discovered. |
Chemistry World July 29, 2014 Vijay Shankar |
Nanoparticle protects protein drug cargo A team of researchers at Brigham and Women's Hospital, Boston, US has developed novel nanoparticles that could deliver protein drugs to where they are needed unscathed. |
Chemistry World October 27, 2014 Tim Wogan |
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. |
Chemistry World October 17, 2011 Andy Extance |
Water erodes 'lock and key' drug model US researchers have dealt a severe blow to the idea of a single 'hydrophobic effect' that can help explain how all drugs dock with proteins. |
Technology Research News June 18, 2003 |
Protein traps nanoparticles Researchers from the University of Tokyo in Japan have adapted a tubular bacterial protein for technological applications by coaxing it to combine with individual luminescent semiconductor nanoparticles. |
Chemistry World October 8, 2008 Sarah Houlton |
Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures. |
Reactive Reports Issue 51 David Bradley |
Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique. |
Chemistry World November 13, 2014 Katrina Kramer |
Persuading proteins to form porous polyhedra Researchers in the US have designed a hollow cube out of naturally occurring proteins, something that was previously only possible with DNA. |
Technology Research News September 24, 2003 Kimberly Patch |
Heated plastic holds proteins One important task for biochips is sorting proteins, but it's tricky business getting protein molecules to be where you want them and stay away from where you don't. A tiny, plastic-coated hot plate allows scientists to trap and release proteins on command. |
Technology Research News December 31, 2003 |
Biochip holds millions of vessels Researchers are putting more of the pieces together to construct full-blown labs-on-a-chip, a possibility that promises inexpensive, hand-held biological, chemical and medical tests similar to the way the computer chip revolutionized electronics. |
HHMI Bulletin Feb 2011 |
DNA Curtains How proteins behave in such a crash test gives scientists data about their structural integrity, how they attach to DNA, and how they behave in a cell. |
Chemistry World February 18, 2008 John Bonner |
Flicking the Acetyl Switch A strain of Escherichia coli that can produce proteins containing an acetylated version of the amino acid lysine could help to reveal how acetylation changes the function of hundreds of proteins inside cells. |
Bio-IT World June 12, 2002 Mark D. Uehling |
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? |
Prepared Foods February 2008 Sharon Book |
Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage. |
Chemistry World July 15, 2010 Simon Hadlington |
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. |
Chemistry World June 6, 2010 Philip Ball |
Blood-like liquid protein formed A liquid form of the oxygen-binding protein myoglobin retains its biological function even though it seems virtually water-free, researchers have found. |
Chemistry World February 24, 2012 Simon Hadlington |
Botox 'bodyguard' gives protein protection Researchers have discovered how one of the most potent toxins known to man can survive in the human stomach and digestive tract. |
Chemistry World January 21, 2011 David Barden |
Close encounter makes modifying proteins easy Chemists in the US have now developed a powerful strategy for selectively modifying the side-chains of proteins, which they hope will enable the creation of new tools to investigate protein interactions involved in human diseases. |
Chemistry World November 2006 Philip Ball |
Opinion: The Crucible Here are some of the latest instalments in the ongoing story of how protein misfolding causes neurodegenerative diseases -- a story that is not solely about developing clinical treatments or preventative medicines, but which goes to the heart of proteins' role as the stuff of life. |
Chemistry World August 26, 2008 Fred Campbell |
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. |
Industrial Physicist Aug/Sep 2003 Ineke Malsch |
Protein research calls for advanced instruments The science of protein interactions is becoming a major tool in biomedical and drug development research. Carrying out and advancing such studies more efficiently and effectively, however, will require new, cutting-edge instrumentation. |
Chemistry World November 27, 2013 Jennifer Newton |
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. |
Technology Research News April 7, 2004 |
Chip-camera combo tracks viruses Researchers from Purdue University have devised methods of labeling virus structural elements and DNA, of imaging virus particles as they flow through labs-on-a-chip, and of concentrating virus particles. |
HHMI Bulletin February 2011 Michele Solis |
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. |
Chemistry World November 25, 2009 Simon Hadlington |
Virus shells traps multiple proteins Scientists in The Netherlands have devised a way to pack large numbers of proteins into the empty shell of a virus. |
Bio-IT World April 16, 2004 Robert Frederickson |
Trial Separations Protein separation through the digital ProteomeChip microchip takes merely minutes, resulting in significantly increased productivity. |
Chemistry World December 19, 2007 Simon Hadlington |
Snapshot of Proteins Linked to Autism Researchers in France and the US have caught on camera the gentle embrace between two proteins that sit on either side of the junction between nerve cells. It's this short circuit that has thought to cause some types of autism. |
Chemistry World March 1, 2010 Andy Extance |
Bacterial mix sweetens biodrug synthesis Bacteria welcome in the human gut are set to become better factories for biological drugs thanks to modified genes from another, gastroenteritis-causing, species. |
Chemistry World February 3, 2013 Andy Extance |
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. |
Chemistry World January 19, 2010 Simon Hadlington |
New 'click' reaction to modify proteins Chemists in the US have discovered a new way to attach small molecules to proteins and peptides under mild, aqueous reaction conditions. |
Chemistry World February 28, 2011 Hayley Birch |
Protein nanotubes trap viruses Japanese researchers have used nanotubes made from human blood proteins to trap hepatitis B virus. They say their work lays the foundations for a new chemistry of protein-based nanotubes with biomedical applications. |
Chemistry World September 25, 2009 Simon Hadlington |
New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
Chemistry World August 17, 2011 Jon Cartwright |
Plasma Treatment to Use Patient's Proteins to Improve Medical Device Biocompatibility Researchers have developed a plasma treatment that can make any medical device biocompatible by sticking a patient's own proteins to it. |
Chemistry World July 23, 2012 Jennifer Newton |
Delivering insulin in a skin cream Scientists in Japan have developed a way to administer insulin to patients through the skin. |
Chemistry World November 13, 2015 Cathy Sorbara |
Hitching a ride on DNA In the congested intracellular environment, scientists in the Netherlands and the US have found a way for molecules to maneuver through the crowds and arrive at their destination faster. |
Technology Research News June 29, 2005 |
Self-assembly: the natural way to make things In biology, there are a few different ways DNA molecules can be replicated and combined. |
Chemistry World July 6, 2007 Michael Gross |
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. |
Chemistry World June 23, 2015 Derek Lowe |
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. |
Bio-IT World July 2005 Robert M. Frederickson |
Amassing Mass Spectrometry Tools Mass spectrometry is a key tool in the effort to identify protein biomarkers of human disease. Manufacturers have met major challenges in adapting this technology to protein discovery, both qualitatively and quantitatively. |
Chemistry World October 2, 2012 Fiona McKenzie |
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. |
Chemistry World December 23, 2015 |
Bones of contention Can protein in dinosaur bones survive for millions of years? Rachel Brazil explores the evidence. |
Chemistry World March 29, 2009 Lewis Brindley |
Gene gels pump out proteins Gels made with genes incorporated into the structure could soon make protein production cheaper and easier, according to researchers in the US. |