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Chemistry World June 14, 2011	A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR.
Chemistry World October 16, 2006 Michael Gross	Brief Encounter Observing fleeting interactions between molecules in solution requires extremely sophisticated methods. NMR spectroscopists have now developed tools that let them watch the transient encounter between two proteins before a well-defined complex is formed.
Chemistry World August 1, 2010 Mike Brown	Snapshots of mystery molecular structures Researchers have used atomic force microscopy to produce clear molecular images that can help determine the correct atomic structure of unknown organic molecules.
Chemistry World January 2, 2014 Ian Randall	Picosecond 'kettle' to probe chemical reactions A way to boil water in less than a trillionth of a second has been devised by researchers. The approach, which is still theoretical, uses a concentrated pulse of terahertz radiation to raise the temperature of a small sample of water by around 600 C.
Chemistry World September 24, 2014 Hayley Simon	Water provides new angle on single molecule imaging Small variations in a molecule's conformation can have a large effect on chemical reactivity. Being able to identify these differences is one of the aims of high resolution spectroscopy.
Chemistry World November 11, 2009 James Urquhart	Structural snapshots of complex molecules US researchers have pioneered a new spectroscopy technique to uncover the precise sequence of atomic movements and structural changes that occur during complex chemical transformations.
Chemistry World June 13, 2012 Simon Hadlington	Exploding molecule provides 3D bond images Researchers from the US and Germany have demonstrated a new way to obtain accurate three-dimensional images of molecules, with precise measurements of the geometry of the molecule's chemical bonds.
Chemistry World September 28, 2010 Lewis Brindley	Helium nanodroplets host ion analysis Chemists have developed a sensitive new infrared spectroscopy method that analyses molecular ions by capturing them in nanosized bubbles of freezing helium.
Chemistry World November 13, 2008 Hayley Birch	Reactions Studied by Stop Motion Japanese and Israeli scientists have developed a technique that can track whole-molecule changes that occur during extremely rapid reactions.
Chemistry World February 18, 2011 Carol Stanier	Speed dating for pharmaceuticals A simple analysis of hydrogen bond strengths finds the best crystallisation partners for drugs, say UK scientists.
Chemistry World January 16, 2012 Kate McAlpine	Stripped down spectroscopy to probe single molecules Spectroscopy, a key method of identifying atoms and molecules with light, has been taken to its most fundamental level - a single photon absorbed by a single molecule.
Chemistry World November 8, 2013 Michael Gross	Speeding up the experiment to fit the simulation In 1997, several groups used atomic force microscopy or laser tweezers to pull single molecules or fragments of titin until some of its domains (structural units) came apart.
Chemistry World October 6, 2011 Manisha Lalloo	Oxygen Isotopes Help to Probe Water's Structure Scientists have used isotopic substitution of oxygen to take a closer look at the molecular structure of water.
Chemistry World September 29, 2010 Hayley Birch	Protein folding: knotted or not A new study may help scientists unravel the complex problem of protein folding. The study suggests knotted proteins, which present a particular challenge to folding experts, could be untied with a couple of well-targeted tugs.
Chemistry World May 21, 2010 Simon Hadlington	H-bond partner-swapping seen in the flesh The dance moves that a water molecule makes as it flips hydrogen bonds from one partner to another have been captured by US researchers.
Chemistry World June 6, 2010 Philip Ball	Blood-like liquid protein formed A liquid form of the oxygen-binding protein myoglobin retains its biological function even though it seems virtually water-free, researchers have found.
Scientific American August 2007 Alison Snyder	Protein Pretense Cheating the standard protein tests is easy, but industry hesitates on alternatives.
Bio-IT World May 2006 Robert M. Frederickson	A New (Bio)Spin on NMR Applications Bruker BioSpin recently announced several introductions to improve throughput, sensitivity, and versatility of its systems for nuclear magnetic resonance applications starting with the SampleJet, a robotics system for high-throughput transfers of NMR sample tubes into the NMR spectrometer.
Chemistry World July 6, 2007 Michael Gross	Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail.
Chemistry World January 3, 2008 Simon Hadlington	Key Plank of Theoretical Chemistry Rescued Theoretical chemists can breathe a sigh of relief after the publication of a study which shows that a cornerstone of their discipline seems to be intact despite earlier evidence to the contrary.
Chemistry World October 8, 2008 Sarah Houlton	Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures.
Chemistry World March 27, 2013 Akshat Rathi	Molecular cages to end crystallization nightmare X-ray crystallography has shaped modern chemistry. It is a powerful tool for molecular structural analysis. But it suffers from one big drawback: it can only analyze materials that form well-defined crystals. This may now be about to change.
Chemistry World June 12, 2013 Kirsty Muirhead	An end to chasing molecules that were never there? Ariel Sarotti from the Rosario National University, Argentina, has developed a new, computationally inexpensive method combining calculated and experimental 13C NMR data to flag up incorrect structures.
Chemistry World June 1, 2012 Simon Hadlington	Protein architecture with atomic precision Researchers have made a key breakthrough in designing and building geometrically defined nanostructures from proteins with unprecedented accuracy.
Chemistry World February 2, 2012 Philip Robinson	Ultrafast NMR shows the way Chemists have created an ultrafast NMR technique that can 'watch' how chemical reactions occur in real time. They've used the technique to follow the formation of pyrimidines from carbonyls and even identified new intermediates never before thought to be part of the reaction.
Reactive Reports November 2007 David Bradley	Organic Uranium The first ever uranium methylidyne molecule has been synthesized by US chemists despite the reactivity of the heavy, heavy metal.
Chemistry World August 13, 2010 James Urquhart	Zooming in on intermolecular bonds German researchers have captured clear images of intermolecular bonds for the first time using a modified form of scanning tunnelling microscopy.
Chemistry World December 15, 2010 Hayley Birch	New technique probes electron properties of individual atoms A new, low voltage electron microscopy technique allows scientists to discriminate not just between atoms of different elements but between atoms of the same element in different electronic states.
Chemistry World September 20, 2013 James Urquhart	Microscopy and spectroscopy combined US researchers have developed a new imaging technique which combines the spatial resolution of scanning tunneling microscopy with vibrational information obtained from infrared spectroscopy.
Chemistry World August 24, 2009 James Urquhart	Separating isomers with electric fields A new technique uses electrostatic fields at ultracold temperatures to isolate individual conformational isomers from a complex molecule.
Reactive Reports May 2007 David Bradley	Meeting of Molecular Movie Stars New footage confirms Linus Pauling's theory of chemical bonding proposed half a century ago, and could help explain molecular recognition processes important throughout supramolecular chemistry and molecular biology.
Chemistry World August 2, 2012 Philip Ball	Polymer replacement for the hydration shell The sheath of water molecules, called a hydration shell, that gives protein molecules the flexibility to do their catalytic job can be replaced by polymers, according to Adam Perriman of the University of Bristol and his coworkers.
Chemistry World October 13, 2011 Phillip Broadwith	Following Electrons' Chemical Reaction Quickstep The oscillating electronic states of molecules nearby and passing through a conical intersection can now be probed directly.
Chemistry World August 21, 2012 James Mitchell Crow	Watching single nanoparticles work By shining laser light on the modified tip of an atomic force microscope), researchers in Germany and the Netherlands have been able to watch a catalytic reaction in real time, zoomed right in to the nanoscale.
Chemistry World January 4, 2007 Henry Nicholls	Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell.
Chemistry World July 28, 2010 Andy Extance	Molecular interference reveals reactions Scientists can now see atoms reacting on the femtosecond timescale in unprecedented detail, thanks to a laser technique developed at the University of Ottawa.
Chemistry World January 9, 2013 Laura Howes	Antifreeze protein's watery dance Most animals left in -30 C temperatures wouldn't last very long. Not only would they get hypothermia, but the water in their bodies would start to freeze. Some animals and plants, however, use antifreeze proteins to keep ice at bay.
Chemistry World January 21, 2011 David Barden	Close encounter makes modifying proteins easy Chemists in the US have now developed a powerful strategy for selectively modifying the side-chains of proteins, which they hope will enable the creation of new tools to investigate protein interactions involved in human diseases.
Bio-IT World June 2006 Kevin Davies	David Shaw: No Hedging on Future of Computer Simulations The computational scientist who founded the world's largest alternative investment firm says he is two years away from building a new breed of computer that could be a major breakthrough in structural biology -- simulating the process of protein folding and protein-drug interactions.
Industrial Physicist Aug/Sep 2003 Ineke Malsch	Protein research calls for advanced instruments The science of protein interactions is becoming a major tool in biomedical and drug development research. Carrying out and advancing such studies more efficiently and effectively, however, will require new, cutting-edge instrumentation.
Chemistry World March 16, 2011	Inspirational science Seong Keun Kim is head of the Molecular Reaction Dynamics Laboratory at Seoul National University, Korea. He uses spectroscopic, microscopic and computational methods to investigate a wide range of subjects from molecular physics and nanoscience to cell biology.
Chemistry World August 2010	Let's get physical The field of physical chemistry is booming, as more and more scientists seek to understand their work on a molecular level
Chemistry World January 21, 2014 Rachel Wood	Centrifuge spectroscopy probes extreme rotational states A new spectroscopic technique for studying electronically excited molecules at very high angular momentum has been developed and tested by scientists in Canada.
Reactive Reports December 2006 David Bradley	Blood, Light, and Water Two molecules that occur naturally in blood have been engineered by scientists to use sunlight to split water into hydrogen and oxygen.
Chemistry World June 5, 2013 Simon Hadlington	Raman scattering reaches sub-nm resolution Researchers have achieved the highest resolution yet with Raman spectroscopy, allowing the chemical mapping of molecules to a resolution of less than 1nm. The technique could allow unprecedented chemical identification of single molecules.
Reactive Reports Issue 51 David Bradley	Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique.
Chemistry World May 21, 2009 James Urquhart	Catalyst kinetics revealed French and UK scientists have developed a spectroscopy technique that has elucidated the reaction mechanism of a silver-alumina catalyst.
HHMI Bulletin Spring 2013 Nicole Kresge	A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology.
HHMI Bulletin Winter 2013 Nicole Kresge	A Structural Revolution Over the years, scientists and artists have used an assortment of techniques to showcase molecular structure.
Bio-IT World October 10, 2003 Jeffrey Skolnick	Protein Structure Prediction in Drug Discovery Indications are that structure prediction can assist in the automated assignment of proteins to known pathways.