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Bio-IT World
December 15, 2003
Malorye A. Branca |
Scenes from a Cell Breakthroughs are making cell-based screening faster, easier, more powerful.   |
Bio-IT World
April 2006
Robert M. Frederickson |
High-Content Cell-Based Imaging Increasingly, equipment providers are incorporating modules for high-content and single-cell analyses into their drug discovery platforms. In addition, new strategies and equipment designs are bringing new types of analysis into the drug discovery marketplace. |
Bio-IT World
July 2005
David M. Evans |
Cellular Imaging Takes Drug Discovery to New Heights The potential applications and ultimate value of high-content screening (HCS) and cellular image analysis are limited only by the imagination and expertise of the drug discovery groups using them to probe gene function and cell behavior. |
Bio-IT World
March 2006
Robert M. Frederickson |
Integration, Robotics, and Automation The integration of instruments and technology is a key concept driving the development of advanced life-sciences laboratory automation. More sophisticated robotics are also increasingly being integrated into automated systems. |
Bio-IT World
January 21, 2005
Robert M. Frederickson |
High-Throughput Science Although genomic assays led the charge toward high-throughput science, new detection systems and formats are enabling the application of high-throughput techniques to proteins and cells. |
Bio-IT World
May 19, 2004
Julia Boguslavsky |
Is Microfluidics Equipped for HTS? As microfluidics technologies mature and increase in throughput, they are starting to offer a highly accurate, flexible, and economical alternative to conventional high-throughput screening (HTS) platforms. |
Bio-IT World
July 2005
Stan Schwartz |
Trends in Digital Bioscience Imaging The author, a Nikon VP, reviews the improvements in digital imaging that have been achieved over the last 30 years. A new set of research tools is aimed at solving the bottlenecks commonly found in the drug discovery laboratory. |
Bio-IT World
September 9, 2002
John P. Helfrich |
Data Management in High-Throughput Screening The high-throughput drug discovery field requires an optimal IT platform. |
Chemistry World
June 13, 2011
Laura Howes |
Cells turned into living lasers with fluorescent protein With a little help from a fluorescent protein, mammalian cells have been transformed into living lasers. This discovery could help improve imaging of living cells, enabling researchers to explore what's going on inside. |
Chemistry World
July 26, 2012
Derek Lowe |
Screen shots You might not think that the makeup of a compound screening collection could set off many arguments, but there are a few issues there that will do the trick almost every time. |
Chemistry World
April 2, 2009
Ned Stafford |
Fluorescent probes take screening to next level Researchers have developed a new high-throughput screening technique that could shed light on the biochemical activities of numerous proteins about which little is currently known. |
Bio-IT World
November 2006
Robert M. Frederickson |
Managing Data on the Go GeneGo has created a suite of software and database products that aim to facilitate analysis of the biology behind different types of high-throughput experimentation and understand the effects of small molecule drug compounds in human tissues. |
Bio-IT World
July 11, 2002
Malorye Branca |
Deep Sequence Diving Like sailors of old, genomic data miners dream of discovering riches and fame. Given the recent improvements in analytics -- and a little more time -- they just might succeed. |
Chemistry World
April 14, 2011
Sarah Farley |
Fish in chips: growing embryos in microfluidic systems Scientists in the Netherlands and the UK have shown for the first time that an animal embryo can develop in a microfluidic environment. |
Bio-IT World
July 15, 2003 |
Millennium's PARIS Illuminates Pathways To address high-throughput-data challenges, Millennium Pharmaceuticals built the PAthway Resource and Information System, or PARIS -- a unique platform for combining knowledge from heterogeneous data sources in the construction of a pathway knowledgebase. |
Bio-IT World
February 18, 2004 |
Strategic Insights High-throughput gene-expression analysis tools are moving rapidly into clinical labs, setting the stage for dramatic improvements in drug development. |
Chemistry World
November 1, 2013
Megan Tyler |
High-throughput chip for drug screening in 3D A simple micro-array chip developed by scientists in China could sharpen the search for new drugs by enabling the high-throughput screening of drug candidates against cells cultured in three dimensions. |
Bio-IT World
January 21, 2005
Mark D. Uehling |
Profiling Drugs via Microscopy With robotic equipment, this Harvard team scans cells faster than researchers can blink their eyes. |
Chemistry World
May 26, 2011
Russell Johnson |
Hunting elusive green fluorescent proteins After a 40 year hunt, scientists have tracked down the genes responsible for fluorescent proteins in Obelia medusa - a type of jellyfish. Knowledge of these genes could lead to new fluorescent protein tags for use in cell biology. |
Bio-IT World
Dec 2006/Jan 2007
Kevin Davies |
The NextBio Thing in Bioinformatics NextBio, which this fall officially introduced its platform after a year of beta testing by a handful of select organizations, aims to provide high-throughput information to researchers without them having to learn anything. |
Bio-IT World
September 2005
Alan Louie |
Molecular Imaging: Smarter and Better The expanding opportunity for molecular imaging (MI) technology to significantly improve drug development has not gone unobserved. Several drug development companies have added imaging capabilities to their arsenal of drug development tools. |
The Motley Fool
September 28, 2006
Ralph Casale |
A Second Sell-Off at Molecular Devices The company, which makes equipment used in drug development, is struggling with lumpy revenues. |
