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Bio-IT World March 2006 Robert M. Frederickson |
Integration, Robotics, and Automation The integration of instruments and technology is a key concept driving the development of advanced life-sciences laboratory automation. More sophisticated robotics are also increasingly being integrated into automated systems. |
Bio-IT World May 19, 2004 Malorye Branca |
Attack of the Lab-Bots Robots are invading every aspect of discovery and development within pharmaceutical companies, from genotyping to high-throughput screening. |
Chemistry World April 2, 2009 Ned Stafford |
Fluorescent probes take screening to next level Researchers have developed a new high-throughput screening technique that could shed light on the biochemical activities of numerous proteins about which little is currently known. |
Industrial Physicist Aug/Sep 2003 Jennifer Ouellette |
A new wave of microfluidic devices Flexibility and a variety of uses are the key |
Pharmaceutical Executive May 1, 2001 |
On Tour with Merck's Robots Merck's HTS robots move assay plates through the screening process. |
Bio-IT World September 11, 2003 Julia Boguslavsky |
Cellular Screening in Sync No longer just a 'good idea,' high-content cellular screening is making an impact in target and lead selection. |
Bio-IT World January 21, 2005 Robert M. Frederickson |
High-Throughput Science Although genomic assays led the charge toward high-throughput science, new detection systems and formats are enabling the application of high-throughput techniques to proteins and cells. |
Bio-IT World September 9, 2002 John P. Helfrich |
Data Management in High-Throughput Screening The high-throughput drug discovery field requires an optimal IT platform. |
Bio-IT World December 15, 2003 Malorye A. Branca |
Scenes from a Cell Breakthroughs are making cell-based screening faster, easier, more powerful. |
Chemistry World April 14, 2011 Sarah Farley |
Fish in chips: growing embryos in microfluidic systems Scientists in the Netherlands and the UK have shown for the first time that an animal embryo can develop in a microfluidic environment. |
Chemistry World May 31, 2009 Nina Notman |
The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used. |
Chemistry World July 26, 2012 Derek Lowe |
Screen shots You might not think that the makeup of a compound screening collection could set off many arguments, but there are a few issues there that will do the trick almost every time. |
Chemistry World November 2009 Derek Lowe |
Column: In the pipeline The author advises opening your mind during the screening cascade taken by potential drug targets, and remaining goal orientated at all times |
Chemistry World July 30, 2015 Derek Lowe |
A precision instrument? How much do medicinal chemists and their biology colleagues really trust each other's data? In the end, they have to, because drug discovery is a team sport. |
Chemistry World November 1, 2013 Megan Tyler |
High-throughput chip for drug screening in 3D A simple micro-array chip developed by scientists in China could sharpen the search for new drugs by enabling the high-throughput screening of drug candidates against cells cultured in three dimensions. |
Chemistry World March 23, 2009 Hayley Birch |
Speeding up screening for chiral catalysts U.S. researchers say their method represents a 'standard workhorse' for discovery and optimisation of chiral catalysts, such as those widely used by the pharmaceutical and pesticide industries. |
Chemistry World May 2010 Derek Lowe |
Column: In the pipeline The author wonders whether tagging molecules with fluorescent labels for assay is like tracking the members of a shoal of fish by tying each one to a whale. In the pharmaceutical business, our work absolutely lives and dies by assay results. |
Chemistry World October 2010 |
Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery |
Chemistry World October 2008 Derek Lowe |
Column: In the pipeline The author seeks a cure for 'compound bloat' |
Pharmaceutical Executive July 1, 2005 Zaborowski, Hammer & Lawler |
Informatics Rules How global computer systems helped far-flung research centers at Roche work together |
Chemistry World July 22, 2014 Harriet Brewerton |
Aaron Wheeler: Algae-on-a-chip Aaron Wheeler is the director of an interdisciplinary research group that develops lab-on-a-chip techniques for applications in biology, chemistry and medicine. |
Bio-IT World April 16, 2004 Malorye Branca |
Finding the Perfect Fit Fragment-based drug discovery is unique and effective. |
Chemistry World December 22, 2009 Rajendrani Mukhopadhyay |
SlipChip serves up protein crystals A simple microfluidic device requiring no pumps or valves can be used to screen for suitable protein crystallisation conditions, claim US researchers. |
Chemistry World September 1, 2008 James Mitchell Crow |
Drug discovery on a chip Scientists in the US have, for the first time, used microfluidics to discover drug leads. The team's lab-on-a-chip device revealed inhibitors of a key membrane-bound protein in hepatitis C virus |
Chemistry World January 7, 2011 Jennifer Newton |
Microfluidic pinball A device to deposit polymer layers on oil droplets has been made by researchers from Singapore, who say that their design is faster and more efficient than conventional deposition techniques and uses microfluidics. |
Bio-IT World November 2006 Kevin Davies |
Building a Bridge Over Pharma with IT More than 100 enthusiastic delegates bridging the full breadth of the drug development pipeline gathered recently for the second annual Bridging Pharma and IT conference. Here are some highlights. |
Chemistry World January 2009 Derek Lowe |
Column: In the pipeline The author discusses the age-old tradition of passing the buck in drug development. |
Chemistry World November 27, 2014 Megan Tyler |
Femtofluidic droplet manipulation now possible We've had microfluidics. We've even had nanofluidics. But now, scientists have gone a step smaller by pushing femtofluidics into the realms of possibility. |