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Bio-IT World February 10, 2003 Robert M. Frederickson |
Bringing Integrated Circuits to Life Cell-sized biochips mean that channels, pumps, and valves must become minuscule, too. |
Chemistry World December 19, 2012 |
Overcoming small obstacles What if photolithography hits a barrier it cannot breach? That question has motivated scientists to recruit chemistry to a series of printing methods with the power to engineer nanometre-scale materials. |
IEEE Spectrum December 2008 Monica Heger |
Cheap Microfluidic Device Made From Paper and Tape Harvard scientists hope to reduce the cost of medical tests |
Technology Research News December 3, 2003 Eric Smalley |
Biochip puts it all together Researchers have made all manner of microfluidic machines, but have yet to come up with cheap, mass-producible biochips for handheld medical and environmental testing. A simple plastic chip puts the necessary pieces together. The $7 device tests blood samples for the presence of E. coli bacteria. |
IEEE Spectrum February 2013 Andrew J. Steckl |
Electronics on Paper Paper electronics could pave the way to a new generation of cheap, flexible gadgets |
Bio-IT World May 19, 2004 Julia Boguslavsky |
Is Microfluidics Equipped for HTS? As microfluidics technologies mature and increase in throughput, they are starting to offer a highly accurate, flexible, and economical alternative to conventional high-throughput screening (HTS) platforms. |
Chemistry World December 22, 2009 Rajendrani Mukhopadhyay |
SlipChip serves up protein crystals A simple microfluidic device requiring no pumps or valves can be used to screen for suitable protein crystallisation conditions, claim US researchers. |
Chemistry World May 30, 2013 Helen Bache |
Microfluidic sugar paper Researchers in the US have demonstrated that the speed of fluid in a paper microfluidic device can be controlled by sugar solutions dried onto the paper. |
Technology Research News March 10, 2004 Kimberly Patch |
Tiny pumps drive liquid circuits Researchers from the University of Illinois at Urbana-Champaign and Lucent Technologies' Bell Laboratories have combined microfluidics and organic electronics to make a tunable plastic transistor that could enable low-cost methods to drive, control and monitor labs-on-a-chip. The device can also use tiny amounts of fluid to adjust optical devices. |
Reactive Reports David Bradley |
Integrated Biochips A new microfluidic device that can perform sample preparation, polymerase chain reaction, and microarray detection functions on a single device has been developed by US researchers. |
Chemistry World January 16, 2007 Michael Gross |
Bioassays Work on Paper New analytical techniques with ever smaller volumes, multiple functionalities, and the ability to run masses of assays in parallel, tend to rely on ever more expensive materials and equipment. Chemists have now bucked this trend by developing a bioassay tool that can be printed on paper. |
Chemistry World September 1, 2008 James Mitchell Crow |
Drug discovery on a chip Scientists in the US have, for the first time, used microfluidics to discover drug leads. The team's lab-on-a-chip device revealed inhibitors of a key membrane-bound protein in hepatitis C virus |
Bio-IT World November 14, 2003 Elizabeth Gardner |
Ultimate Analysis With the necessary tools at hand, the race is on to build -- and market -- the first affordable, portable, fully functional DNA analyzer. Is the world ready? |
Technology Research News May 7, 2003 Eric Smalley |
Sound forms virtual test tubes Microfluidics devices usually consist of microscopic chambers and tunnels made from silicon, glass or plastic. Researchers from the University of Washington have taken a different tack. Their microscale device uses sound waves to trap and mix tiny amounts of substances. |
Bio-IT World May 19, 2004 Malorye Branca |
Attack of the Lab-Bots Robots are invading every aspect of discovery and development within pharmaceutical companies, from genotyping to high-throughput screening. |
Chemistry World October 15, 2009 Simon Hadlington |
Optical conveyor belt gathers up molecules Researchers in Germany have developed a novel way to 'round up' biological molecules that are freely suspended in solution and trap them in a confined space using nothing more than light. |
Chemistry World February 25, 2011 Elinor Richards |
Diagnosing diseases with CDs A digital compact disc integrated with a microfluidic device to analyse cells has been developed by scientists in the US. The disc can be inserted into a standard computer disc drive for analysis and could be used to diagnose diseases. |
IEEE Spectrum November 2009 Jeffrey T. Borenstein |
Flexible Microsystems Deliver Drugs Through the Ear A microelectromechanical systems-based microfluidic implant could open up many difficult-to-treat diseases to drug therapy |
Bio-IT World Dec 2005/Jan 2006 Robert M. Frederickson |
Labcyte Demonstrates 'Sound' Transfer As mundane as the topic of fluid management may seem, it is big business. And this developer of microfluidic systems' new technology is well suited to high-throughput biological applications where large numbers of different fluids must be transferred rapidly and sequentially. |
Bio-IT World January 21, 2005 Laura Lane |
Speed It Up Although mostly used for manufacturing and pharmaceutical research, automated devices are becoming increasingly common in academia and small labs. |
Chemistry World February 22, 2013 Anthony King |
LED triggers microfluidic mixing French scientists have developed a way to mix fluids in microfluidic devices using light from an external LED as a trigger. The strategy is simple but offers good control over mixing without complex components. |
Bio-IT World Jul/Aug 2006 Robert M. Frederickson |
Tests for Hospital-Acquired Infections Tests for pathogens increasingly rely on genomic methods that identify specific genetic signatures of bacteria or viruses. Rapid detection of other pathogens also provides the potential for significant impact on the healthcare industry. |
BusinessWeek January 13, 2011 Ira Boudway |
Innovator: Stephen Quake Stanford bio-engineer Stephen Quake has created a rubber chip that makes gene research faster, easier, and more precise. |
Chemistry World May 17, 2007 Michael Gross |
Further Integration of Micro Fluidics and Mass Spec Chemists in Germany have created a glass microchip that combines microfluidic channels with a nanospray emitter for electrospray ionization mass spectrometry. |
Technology Research News October 20, 2004 Eric Smalley |
Wide laser makes simple tweezers Much of medical diagnostics and biomedical research involves trapping, manipulating and sorting individual cells and like-sized bits of matter. A recently demonstrated way of manipulating cells promises to be less expensive than laser tweezers. |
National Defense July 2004 Joe Pappalardo |
Scientists Seek Breakthroughs In Bio-Detection The Department of Homeland Security is seeking to upgrade its biological sensor network with more encompassing and less costly systems. |
Bio-IT World October 14, 2004 Robert M. Frederickson |
Nanosphere Strikes Gold Recently, scientists at Nanosphere developed a colorimetric method for DNA detection that obviates the need for target or signal amplification. |
Bio-IT World January 21, 2005 Robert M. Frederickson |
High-Throughput Science Although genomic assays led the charge toward high-throughput science, new detection systems and formats are enabling the application of high-throughput techniques to proteins and cells. |
Chemistry World March 12, 2012 Francesca Burgoyne |
Genetic testing? We've got an app for that US scientists have developed a device dubbed Gene-Z for point-of-care genetic testing using a smartphone interface that has realistic commercial potential. |
Chemistry World September 15, 2011 Tamsin Phillips |
Corn Microchips US scientists have made microfluidic devices from a corn by-product, which makes them biodegradable and environmentally friendly. |
Chemistry World May 9, 2007 Lionel Milgrom |
Multinozzle to Speed up Lab-on-a-Chip Proteomics The pace of proteomics research is set to increase, thanks to the development of a new device that interfaces lab-on-a-chip technology with a conventional mass spectrometer. |
Chemistry World November 10, 2011 Francesca Burgoyne |
Micro fuel cells for microchips Researchers from Spain and Germany have designed the first microfluidic device with an integrated micro fuel cell that is capable of both powering the device and pumping the analyte around the device. |
Chemistry World July 22, 2014 Harriet Brewerton |
Aaron Wheeler: Algae-on-a-chip Aaron Wheeler is the director of an interdisciplinary research group that develops lab-on-a-chip techniques for applications in biology, chemistry and medicine. |
Chemistry World February 8, 2007 Tom Westgate |
Bubbles Put the Logic Into Lab-on-a-Chip The boundary between computing and chemistry has been redrawn, thanks to devices that mimic digital processors using the physical properties of flowing liquids and bubbles. |
Chemistry World November 27, 2014 Megan Tyler |
Femtofluidic droplet manipulation now possible We've had microfluidics. We've even had nanofluidics. But now, scientists have gone a step smaller by pushing femtofluidics into the realms of possibility. |
Chemistry World December 16, 2013 Michael Parkin |
1024 samples analysed on a single chip Researchers in Switzerland have developed a microfluidic platform able to measure four protein biomarkers in over 1000 blood samples on a single microfluidic chip. |
Chemistry World October 7, 2015 Christopher Barnard |
Microfluidic device lets the drop beat Scientists in Switzerland have incorporated pulsing human heart tissue into a microfluidic device to make a model of a living system that could be used to test new drugs. |
Technology Research News November 5, 2003 Kimberly Patch |
Micro waterflows make power Apply electricity to a microscopic tube of water and the water flows. Turn the equation around and force water through the tube instead, and electricity flows. Put enough of the tiny tubes together -- several million or so -- and you get useful amounts of power, and a new, clean source of energy. |
Chemistry World October 31, 2012 Ian Le Guillou |
A cell for a cell If you ever need to isolate a single bacterial cell, why not build it a prison cell? This is the approach that colleagues from Sandia National Laboratories, US, have taken. Using multi-photon lithography, they can construct four walls and a roof around a single cell in just over a minute. |
Bio-IT World April 16, 2004 Robert Frederickson |
Trial Separations Protein separation through the digital ProteomeChip microchip takes merely minutes, resulting in significantly increased productivity. |
Scientific American March 2009 Elaine Schattner |
A Chip against Cancer: Microfluidics Scrutinizes T Cells With just a blood sample, a device could determine whether cancer is about to spread or monitor the progress of treatment |
Chemistry World March 22, 2011 Amaya Camara-Campos |
Microfluidics to diagnose sleeping sickness Jonas Tegenfeldt from the University of Lund developed a microfluidic device that separates the parasites in this disease from the blood cells using their shape, because parasites and red blood cells are very difficult to separate by size. |
Chemistry World March 19, 2015 James Urquhart |
Mystery of colored water droplets that chase and repel each other solved Researchers have solved the puzzle of a remarkable phenomenon that allows droplets of water mixed with a food coloring to move spontaneously and freely in intricate patterns when placed on a clean glass slide. |
Chemistry World September 16, 2013 Megan Tyler |
Reprogrammable microfluidic chips The time-consuming and costly manufacturing processes required to construct microfluidic devices, makes the idea of a reprogrammable chip very attractive. |
Chemistry World February 16, 2011 Harriet Brewerton |
Remote powered lab on a chip Wen Qiao at the University of California, San Diego, made a microfluidic chip that can be powered with a commercially available radio frequency transmitter for electrophoresis experiments. |
Chemistry World October 1, 2014 Katrina Kramer |
Microfluidics for the masses US scientists have developed a series of microfluidic building blocks that allow researchers to construct devices by assembling the components like Lego. |
Chemistry World May 28, 2015 Cesar Palmero |
Gecko-inspired adhesives for microfluidics Scientists from Canada report an affordable manufacturing advance in microfluidics with a dry adhesive system that demonstrates strong, self-healing and reversible bonding. |
Chemistry World March 5, 2014 Jennifer Newton |
Microfluidic fuel cells on paper Instrument-free point-of-care diagnostic devices could be taken to the next level with the development of microfluidic fuel cells on paper. |
Chemistry World November 19, 2007 Jonathan Edwards |
Sorting Droplets Digitally Scientists in Hong Kong have developed a lab-on-a-chip device that can separate and identify picolitre droplets quickly, cheaply and accurately. |
Technology Research News March 24, 2004 |
Triangles form one-way channels The microfluidic rectifier could be used in integrated microfluidic circuits, which use control fluids to operate pumps and valves that move samples and reagents in biochips. |