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Chemistry World October 2008 Derek Lowe	Column: In the pipeline The author seeks a cure for 'compound bloat'
Information Today November 13, 2006 Ed Vawter	Thomson Pharma Adds 2.2 Million Chemical Structures to PubChem Database While it is exciting to see content from a major information source such as Thomson Pharma get incorporated into a freely available government-sponsored database such as PubChem, there are still drawbacks.
Chemistry World September 29, 2015	Navigating chemical space How big is chemistry? I don't mean how important is it, or how many people do it, but rather, how many molecules are there that we could make?
Bio-IT World August 18, 2004 Kevin Davies	In Praise of Chemical Diversity How to build better small-molecule libraries.
Chemistry World November 2011 Derek Lowe	Column: In the Pipeline In recent years there's another class of 'unknown' compounds that's become more prominent than ever: the ones you can buy from the chemical catalogues.
Chemistry World October 2010	Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery
Chemistry World February 8, 2006 Jon Evans	To Boldly go Where no Chemist Has Gone Before Studying the interactions between different molecular fragments is taking researchers to the uncharted regions of chemical space.
Chemistry World June 2008 Sarah Houlton	Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success
Chemistry World May 20, 2015 Katrina Kramer	Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs.
Chemistry World March 5, 2015 Emma Stoye	Forgotten synthetic PhD theses set to be given new lease of life A team of researchers have amassed a digital collection of more than 75,000 compounds from PhD theses that might otherwise have mouldered in obscurity.
Chemistry World May 31, 2009 Nina Notman	The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used.
Chemistry World November 18, 2014 Katrina Kramer	Molecules: the elements and the architecture of everything Molecules is a serious attempt to explain the world of chemical compounds to the reader without assuming previous science knowledge.
Chemistry World August 2009 Derek Lowe	Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder
Chemistry World April 25, 2013 Andreas Barth	Chemical bibliometrics Counting compounds instead of publications and citations opens new perspectives for data-based scientific discovery and it can complement and stimulate both experimental and theoretical research.
ONLINE Sep/Oct 2007 Svetla Baykoucheva	A New Era in Chemical Information: PubChem, DiscoveryGate, and Chemistry Central How the emergence of PubChem, DiscoveryGate and Chemistry Central are changing the field of chemical information.
Chemistry World July 26, 2012 Derek Lowe	Screen shots You might not think that the makeup of a compound screening collection could set off many arguments, but there are a few issues there that will do the trick almost every time.
Chemistry World June 28, 2013 Phillip Broadwith	Data-sharing partnership for drug discovery AstraZeneca and Roche are pooling their data on compound properties to boost their chances of success in early stage drug development.
Chemistry World January 2012	Rising interest in compound bank David Fox argues for the creation of a centralized repository for small molecules to harness research efforts in drug discovery
The Motley Fool May 25, 2007 Brian Orelli	Amylin Sifts for Gold The biotech mines extra value from its compound library. Investors, take note.
Chemistry World June 1, 2012 Derek Lowe	Peace, love and understanding You'd think that the chemists and biologists working in drug discovery would understand each other pretty well by now. You would be wrong about that.
Chemistry World May 20, 2015 Katrina Kramer	Molecules that amaze us For chemistry-savvy readers, the book is an enjoyable, easy-to-digest collection of fascinating molecules to dip in and out of.
Reactive Reports November 2007 David Bradley	Organic Uranium The first ever uranium methylidyne molecule has been synthesized by US chemists despite the reactivity of the heavy, heavy metal.
Chemistry World May 29, 2015 Derek Lowe	Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways.
Chemistry World March 27, 2014 Derek Lowe	Known unknowns Most dangerous substances announce themselves by their structures and reactivity, and a competent organic chemist should be able to read those signs.
Bio-IT World February 10, 2003 Malorye Branca	Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic.
Chemistry World May 27, 2008 Simon Hadlington	Computer brain unearths better insect repellents Mosquitoes seeking to gorge on human blood could soon be faced with a new range of chemicals designed to put them off, thanks to new research.
Chemistry World August 21, 2008 Fred Campbell	Double bonding with silicon In a landmark for silicon chemistry, US researchers have reported the first stable silicon (0) compound to contain a silicon-silicon double bond.
Chemistry World May 22, 2008 Richard Van Noorden	Xenon doubled up with water Creating a water molecule with two noble gas atoms interpolated into its structure sounds an improbable feat, but a international team of researchers now claim to have trapped just such an exotic compound in xenon.
Bio-IT World November 19, 2004 Kevin Davies	De-Lovely Pharmaceuticals De Novo Pharmaceuticals identifies novel compounds right before your eyes.
Wired Erin Biba	Molecular Frameworks, the Building Blocks of All Life The world is complicated, but not as complicated as you might think. Most organic molecules derive from a few relatively simple architectures.
Chemistry World January 20, 2010 James Urquhart	Disilicate synthesis success A compound containing a stable silicon-silicon bond between two negatively charged pentacoordinated silicon atoms - silicates - has been synthesized and isolated for the first time by Japanese researchers.
Bio-IT World September 2006 Kevin Davies	Pfizer's Global Survey of Pharmacological Space The pharma blends knowledge, computational chemistry and research informatics to build a unified database. Gathering all the data in one place offered greater control for indexing and data retrieval and management, enabling Pfizer scientists to perform global mapping.
Chemistry World January 3, 2012 Simon Hadlington	One-pot synthesis creates anticancer candidates Researchers in Germany have developed a simple, rapid and high-yielding cascade synthesis of a collection of polycyclic compounds that resemble indole alkaloid natural products and which interfere with cell division.
Chemistry World September 7, 2014 Michael Gross	Bringing chemical synthesis to the masses The promise of a novel approach to building chemical libraries, which only requires simple building blocks in water, without any additional reagents or sample preparation, is inspired by nature.
Chemistry World July 3, 2014 Tami Spector	Of atoms and aesthetics Molecular aesthetics means many things to a few people. For some it means tangible aspects of compounds; for others yet, the ways that chemists represent molecules.
Chemistry World January 20, 2014 David Bradley	Molecular librarians create druglike collections Finding biologically active small molecules with pharmaceutical potential is a bittersweet process. Now, a new approach to building libraries of diverse alkaloid-type structures has been developed by US chemists.
Chemistry World August 2008	Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now?
Chemistry World November 28, 2013	Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity.
Reactive Reports December 2006 David Bradley	Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database.
Reactive Reports Issue 40 David Bradley	That INChI Feeling Researchers have worked to develop a means for identifying chemical structures on a computer without having to work out a complex, standard nomenclature for each one.
Chemistry World June 14, 2012 David Bradley	Tripling up on boron bonds Carbon and nitrogen are well known for their triple bonds, but making stable compounds with a triple bond between two boron atoms hadn't been achieved despite the computational possibilities. Until now.
Reactive Reports Issue 63 David Bradley	Chemists Go Round the Bend Chemists often think of molecular wires as "shape-persistent" rods with limited flexibility, but researchers have now shown that molecular wires can be bent into ring shapes.
Chemistry World January 6, 2009 Rebecca Trager	Web chemistry progresses InChI by InChI InChIs enable people to look up and find information on a particular chemical very quickly
Bio-IT World October 2006 Robert M. Frederickson	Fast Track to Compounds and Crystals Nexus Biosystems' IRORI systems allows synthesis of tens to tens of thousands of compounds. Nexus' Kan Reactors are miniaturized devices that contain both a functionalized solid phase support and a unique tag identifier for the synthesis of a discrete compound.
Chemistry World December 19, 2011 Rebecca Trager	US agencies collaborate to test 10,000 chemicals A high-speed robotic screening system jointly initiated by three key US health agencies began testing more than 10,000 chemical compounds for potential toxicity on 7 December.
Chemistry World January 2012	Column: In the pipeline Derek Lowe discusses how companies are increasingly trying to do more with the compounds they already know a lot about
Chemistry World January 2008 Philip Ball	Column: The Crucible Does chemical space limit a chemists' creativity?
Chemistry World August 13, 2015	Exploiting the data mine Chemists must embrace open data to allow us to collectively get the best out of the masses of new knowledge we unearth, reports Clare Sansom
Bio-IT World April 2007 Vicki Glaser	Software Solutions for Medicinal Chemistry Driven by advances in chemical synthesis, instrumentation, and high-throughput and high-content screening technology, medicinal chemistry's transition from an art to a science is benefiting from a wealth of new software products, spanning both bio- and cheminformatics.
Chemistry World November 30, 2007 Lewis Brindley	Crystal Clear Structure Prediction One team of researchers has hit the jackpot by correctly predicting the crystal structures of four organic molecules in a competition organized by the University of Cambridge.