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Chemistry World August 20, 2012 Phillip Broadwith |
Fluoroborates Without the Etch A simple, practical method for making popular trifluoroborate reagents without etching glassware or tedious purification procedures has been developed by chemists in the UK. |
Chemistry World June 8, 2014 David Bradley |
Carbon--carbon couplings go 3D Chemists have devised a new stereospecific coupling reaction for electron-rich aromatics using secondary and tertiary boronic esters that works under mild conditions. |
Chemistry World April 12, 2012 Simon Hadlington |
Recruiting electrophiles for organic cross-coupling Chemists in the US have taken an unconventional approach to carbon cross-coupling and in doing so have potentially opened the door to the rapid and efficient synthesis of a wide range of organic compounds. |
Chemistry World May 24, 2007 James Mitchell Crow |
Palladium Coupling in Fewer Steps Look out Suzuki - Canadian chemists have successfully joined up simple benzene ring-like aromatics without any pre-activation. |
Chemistry World October 6, 2010 Simon Hadlington |
Trio share Nobel for palladium-catalysed cross-coupling Richard Heck of the University of Delaware in Newark, US, Ei-ichi Negishi of Purdue University, US, and Akira Suzuki of Hokkaido University in Japan, independently developed palladium-catalysed cross-coupling reactions as a way to forge new carbon-carbon bonds with precision |
Chemistry World November 2010 |
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. |
Chemistry World August 16, 2009 Tom Bond |
Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis. |
Chemistry World October 12, 2015 Emma Stoye |
Chemistry Nobel laureate Richard Heck dies Richard Heck, the organic chemist who shared the 2010 chemistry Nobel prize with for developing palladium-catalyzed cross coupling reactions, has died aged 84. |
Chemistry World April 18, 2012 Elinor Richards |
Homogeneous Catalyst Recovery Made Easier Scientists have now found a way to recover homogeneous catalysts at the end of a chemical reaction that doesn't suffer from the slow reaction rates that affect current catalyst recovery systems. |
Chemistry World April 15, 2012 Jon Evans |
Synthetic chemists print labware to order Not only do 3D printers offer the possibility of producing vessels with much more complex architectures, but the vessels can be designed to influence the course of the reaction or even to take part in it. |
Chemistry World November 3, 2008 Simon Hadlington |
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? |
Chemistry World December 20, 2007 Richard Van Noorden |
Off-the-Peg Organic Synthesis Goes Commercial Chemists have created an efficient way to make small molecules by repeatedly using just one coupling reaction to clip together pre-prepared chemical fragments is going commercial. |
Chemistry World May 26, 2015 |
Catching the runaways I think each cohort of industrial chemists has a runaway industrial reaction that defines their generation. |
Chemistry World December 5, 2012 Phillip Broadwith |
Chemical reactions in hot water Chinese and Japanese chemists have highlighted hot water's ability to promote unexpected reactions without any other reagents or catalysts. The work should expand our understanding of how to harness the physicochemical properties of water to potentially replace more complex reagents and catalysts. |
Chemistry World April 10, 2008 Mark Peplow |
'Pot-in-a-Pot' Technique Makes Impossible Cascade Reactions Easy A simple technique that nests a series of reaction vessels could help chemists avoid the tedium and expense of purifying organic compounds after each step of a long synthesis. |
Chemistry World July 14, 2009 Phillip Broadwith |
Multicomponent reactions step up a gear Dutch chemists have taken multicomponent reactions to the next level, combining a total of eight different starting materials in a single flask, bringing together three different multicomponent reactions and making nine new bonds in a single step. |
Chemistry World January 25, 2013 Derek Lowe |
Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers? |
Chemistry World February 6, 2011 Laura Howes |
Cells as test tubes Chemists have used living cells as test tubes to carry out chemical reactions never before seen within living cells. |
Chemistry World August 2008 |
Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now? |
Chemistry World March 20, 2008 James Mitchell Crow |
Surfactants Help Reactions Work in Water Scientists have discovered a surfactant that allows the catalytic organic reactions commonly used to assemble organic structures such as drug molecules to be run in water. |
Chemistry World December 3, 2010 Elinor Richards |
Graphene catalyst comes out on top Sulfonated graphene solid acid catalysts could be cheap, environmentally friendly alternatives to concentrated sulfuric acid for use in industry because they can be recycled, say scientists from China. |
Chemistry World November 2007 Derek Lowe |
Column: In the Pipeline Chemists are finally going with the flow. |
Chemistry World November 25, 2014 James Urquhart |
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. |
Chemistry World October 2009 |
Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions |
Chemistry World September 4, 2012 Derek Lowe |
Light in the Lab We organic chemists do terrible things to our molecules. How about dissolving the starting materials up in a flask, shining a light into the mixture and coming back later to find it transformed into your product? That's photochemistry. |
Chemistry World February 20, 2013 Amy Middleton-Gear |
Ohmic heating for efficient green synthesis Portuguese scientists have developed a new ohmic-heating reactor for organic syntheses on water, or chemistry using an aqueous suspension of the reactants. |
Chemistry World September 30, 2009 Simon Haddlington |
Porous networks trap reactive intermediates Chemists in Japan have shown how it is possible to take sequential x-ray snapshots of chemical reactions taking place within molecular-sized 'reaction chambers', capturing the crystal structures of short-lived reactive intermediates. |
Chemistry World November 21, 2011 David Bradley |
Zombie reaction returns from the dead An oscillating reaction that apparently stops after 10 hours, but is then resurrected spontaneously several hours later, has been discovered by a group of chemistry students at the Mito Dai-ni senior high school in Ibaraki, Japan. |
Chemistry World August 2010 Paul Docherty |
Column: Totally Synthetic The total synthesis of macrolide targets is now a relatively mature field. Any synthesis that bucks these trends grabs attention, with a recent publication of dictyosphaeric acid A by Richard Taylor's team at the University of York, UK, a case in point. |
Chemistry World April 25, 2014 Derek Lowe |
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. |
Chemistry World January 13, 2011 Sarah Corcoran |
Unclogging the problems of flow chemistry US scientists have found a way to stop solid byproducts clogging channels in continuous flow reactors, a problem that has hampered their progress for use in manufacturing pharmaceuticals. |
Chemistry World September 9, 2011 James Mitchell Crow |
High-throughput catalyst screening for the masses Using nothing more than the standard chemistry lab equipment, researchers in the US have successfully turned the discovery of new catalytic reactions into a high-throughput process. |
Chemistry World August 22, 2014 Derek Lowe |
Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today. |
Chemistry World September 26, 2012 Derek Lowe |
Under pressure Someone interviewing for a synthetic chemistry position had better know his or her organic chemistry. It's fair to ask questions that will make sure of that. But does a candidate need to know the curly-arrow details of reactions that they'll never run? |
Chemistry World September 24, 2014 Richard Massey |
Acetaldehyde photolysis: right to roam Australian and US chemists have re-shaped our understanding of an important photochemical reaction that defies classical transition state theory and proceeds via multiple barrierless 'roaming' pathways. |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World June 19, 2013 John Hayward |
Science of synthesis workbench edition: water in organic synthesis If a chemist is looking to do chemistry in (or on) water at the bench, Water in organic synthesis by Shu Kobayashi will be their guide. |
Chemistry World October 16, 2015 Philippa Matthews |
One pot recipe for incompatible catalytic transformations Researchers from the US have demonstrated a new catalyst support structure allowing two incompatible catalysts to work in tandem. |
Chemistry World August 2007 Derek Lowe |
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. |
Reactive Reports December 2006 David Bradley |
Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database. |
Chemistry World October 2011 Paul Docherty |
Column: Totally Synthetic Antioxidants are not only found in human cells, but also in bacterial cell walls - and a good example is synechoxanthin. |
Chemistry World December 21, 2010 James Urquhart |
Cellulose catalyst rewrites rules of attraction Chinese researchers have developed a magnetic solid acid catalyst that raises the prospect of efficiently converting biomass cellulose into useful chemicals, such as sugars for biofuel production. |
Chemistry World August 13, 2007 Simon Hadlington |
Nature Captured in a Test-Tube Two groups of researchers have demonstrated how a complex chain of reactions catalyzed by multiple enzymes can be reconstructed in the test tube to synthesize naturally occurring products that have potential therapeutic properties. |
Chemistry World June 24, 2012 |
An Invaluable Resource In the new edition of "Organic Syntheses Based on Name Reactions: A Practical Guide to 750 Transformations," the authors deliver a comprehensive guide to named reactions in organic synthesis. |
Chemistry World June 20, 2012 Rebecca Brodie |
Faster removal of cigarette filters from the environment Filters can take years to degrade. Celanese Corporation has been working to develop a filter that contains a controlled-release organic acid to catalyse the hydrolysis of the filter material. |
Chemistry World November 10, 2015 Elisabeth Ratcliffe |
Eucalyptus bears both catalyst and biofuel Japanese researchers who have devised a method using eucalyptus trees that regenerates residue from the process into fresh catalyst. |