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Chemistry World
August 20, 2012
Phillip Broadwith
Fluoroborates Without the Etch A simple, practical method for making popular trifluoroborate reagents without etching glassware or tedious purification procedures has been developed by chemists in the UK. mark for My Articles similar articles
Chemistry World
June 8, 2014
David Bradley
Carbon--carbon couplings go 3D Chemists have devised a new stereospecific coupling reaction for electron-rich aromatics using secondary and tertiary boronic esters that works under mild conditions. mark for My Articles similar articles
Chemistry World
April 12, 2012
Simon Hadlington
Recruiting electrophiles for organic cross-coupling Chemists in the US have taken an unconventional approach to carbon cross-coupling and in doing so have potentially opened the door to the rapid and efficient synthesis of a wide range of organic compounds. mark for My Articles similar articles
Chemistry World
May 24, 2007
James Mitchell Crow
Palladium Coupling in Fewer Steps Look out Suzuki - Canadian chemists have successfully joined up simple benzene ring-like aromatics without any pre-activation. mark for My Articles similar articles
Chemistry World
October 6, 2010
Simon Hadlington
Trio share Nobel for palladium-catalysed cross-coupling Richard Heck of the University of Delaware in Newark, US, Ei-ichi Negishi of Purdue University, US, and Akira Suzuki of Hokkaido University in Japan, independently developed palladium-catalysed cross-coupling reactions as a way to forge new carbon-carbon bonds with precision mark for My Articles similar articles
Chemistry World
November 2010
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. mark for My Articles similar articles
Chemistry World
August 16, 2009
Tom Bond
Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis. mark for My Articles similar articles
Chemistry World
October 12, 2015
Emma Stoye
Chemistry Nobel laureate Richard Heck dies Richard Heck, the organic chemist who shared the 2010 chemistry Nobel prize with for developing palladium-catalyzed cross coupling reactions, has died aged 84. mark for My Articles similar articles
Chemistry World
April 18, 2012
Elinor Richards
Homogeneous Catalyst Recovery Made Easier Scientists have now found a way to recover homogeneous catalysts at the end of a chemical reaction that doesn't suffer from the slow reaction rates that affect current catalyst recovery systems. mark for My Articles similar articles
Chemistry World
April 15, 2012
Jon Evans
Synthetic chemists print labware to order Not only do 3D printers offer the possibility of producing vessels with much more complex architectures, but the vessels can be designed to influence the course of the reaction or even to take part in it. mark for My Articles similar articles
Chemistry World
November 3, 2008
Simon Hadlington
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? mark for My Articles similar articles
Chemistry World
December 20, 2007
Richard Van Noorden
Off-the-Peg Organic Synthesis Goes Commercial Chemists have created an efficient way to make small molecules by repeatedly using just one coupling reaction to clip together pre-prepared chemical fragments is going commercial. mark for My Articles similar articles
Chemistry World
May 26, 2015
Catching the runaways I think each cohort of industrial chemists has a runaway industrial reaction that defines their generation. mark for My Articles similar articles
Chemistry World
December 5, 2012
Phillip Broadwith
Chemical reactions in hot water Chinese and Japanese chemists have highlighted hot water's ability to promote unexpected reactions without any other reagents or catalysts. The work should expand our understanding of how to harness the physicochemical properties of water to potentially replace more complex reagents and catalysts. mark for My Articles similar articles
Chemistry World
April 10, 2008
Mark Peplow
'Pot-in-a-Pot' Technique Makes Impossible Cascade Reactions Easy A simple technique that nests a series of reaction vessels could help chemists avoid the tedium and expense of purifying organic compounds after each step of a long synthesis. mark for My Articles similar articles
Chemistry World
July 14, 2009
Phillip Broadwith
Multicomponent reactions step up a gear Dutch chemists have taken multicomponent reactions to the next level, combining a total of eight different starting materials in a single flask, bringing together three different multicomponent reactions and making nine new bonds in a single step. mark for My Articles similar articles
Chemistry World
January 25, 2013
Derek Lowe
Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers? mark for My Articles similar articles
Chemistry World
February 6, 2011
Laura Howes
Cells as test tubes Chemists have used living cells as test tubes to carry out chemical reactions never before seen within living cells. mark for My Articles similar articles
Chemistry World
August 2008
Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now? mark for My Articles similar articles
Chemistry World
March 20, 2008
James Mitchell Crow
Surfactants Help Reactions Work in Water Scientists have discovered a surfactant that allows the catalytic organic reactions commonly used to assemble organic structures such as drug molecules to be run in water. mark for My Articles similar articles
Chemistry World
December 3, 2010
Elinor Richards
Graphene catalyst comes out on top Sulfonated graphene solid acid catalysts could be cheap, environmentally friendly alternatives to concentrated sulfuric acid for use in industry because they can be recycled, say scientists from China. mark for My Articles similar articles
Chemistry World
November 2007
Derek Lowe
Column: In the Pipeline Chemists are finally going with the flow. mark for My Articles similar articles
Chemistry World
November 25, 2014
James Urquhart
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. mark for My Articles similar articles
Chemistry World
October 2009
Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions mark for My Articles similar articles
Chemistry World
September 4, 2012
Derek Lowe
Light in the Lab We organic chemists do terrible things to our molecules. How about dissolving the starting materials up in a flask, shining a light into the mixture and coming back later to find it transformed into your product? That's photochemistry. mark for My Articles similar articles
Chemistry World
February 20, 2013
Amy Middleton-Gear
Ohmic heating for efficient green synthesis Portuguese scientists have developed a new ohmic-heating reactor for organic syntheses on water, or chemistry using an aqueous suspension of the reactants. mark for My Articles similar articles
Chemistry World
September 30, 2009
Simon Haddlington
Porous networks trap reactive intermediates Chemists in Japan have shown how it is possible to take sequential x-ray snapshots of chemical reactions taking place within molecular-sized 'reaction chambers', capturing the crystal structures of short-lived reactive intermediates. mark for My Articles similar articles
Chemistry World
November 21, 2011
David Bradley
Zombie reaction returns from the dead An oscillating reaction that apparently stops after 10 hours, but is then resurrected spontaneously several hours later, has been discovered by a group of chemistry students at the Mito Dai-ni senior high school in Ibaraki, Japan. mark for My Articles similar articles
Chemistry World
August 2010
Paul Docherty
Column: Totally Synthetic The total synthesis of macrolide targets is now a relatively mature field. Any synthesis that bucks these trends grabs attention, with a recent publication of dictyosphaeric acid A by Richard Taylor's team at the University of York, UK, a case in point. mark for My Articles similar articles
Chemistry World
April 25, 2014
Derek Lowe
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. mark for My Articles similar articles
Chemistry World
January 13, 2011
Sarah Corcoran
Unclogging the problems of flow chemistry US scientists have found a way to stop solid byproducts clogging channels in continuous flow reactors, a problem that has hampered their progress for use in manufacturing pharmaceuticals. mark for My Articles similar articles
Chemistry World
September 9, 2011
James Mitchell Crow
High-throughput catalyst screening for the masses Using nothing more than the standard chemistry lab equipment, researchers in the US have successfully turned the discovery of new catalytic reactions into a high-throughput process. mark for My Articles similar articles
Chemistry World
August 22, 2014
Derek Lowe
Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today. mark for My Articles similar articles
Chemistry World
September 26, 2012
Derek Lowe
Under pressure Someone interviewing for a synthetic chemistry position had better know his or her organic chemistry. It's fair to ask questions that will make sure of that. But does a candidate need to know the curly-arrow details of reactions that they'll never run? mark for My Articles similar articles
Chemistry World
September 24, 2014
Richard Massey
Acetaldehyde photolysis: right to roam Australian and US chemists have re-shaped our understanding of an important photochemical reaction that defies classical transition state theory and proceeds via multiple barrierless 'roaming' pathways. mark for My Articles similar articles
Chemistry World
May 29, 2015
Derek Lowe
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. mark for My Articles similar articles
Chemistry World
June 19, 2013
John Hayward
Science of synthesis workbench edition: water in organic synthesis If a chemist is looking to do chemistry in (or on) water at the bench, Water in organic synthesis by Shu Kobayashi will be their guide. mark for My Articles similar articles
Chemistry World
October 16, 2015
Philippa Matthews
One pot recipe for incompatible catalytic transformations Researchers from the US have demonstrated a new catalyst support structure allowing two incompatible catalysts to work in tandem. mark for My Articles similar articles
Chemistry World
August 2007
Derek Lowe
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. mark for My Articles similar articles
Reactive Reports
December 2006
David Bradley
Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database. mark for My Articles similar articles
Chemistry World
October 2011
Paul Docherty
Column: Totally Synthetic Antioxidants are not only found in human cells, but also in bacterial cell walls - and a good example is synechoxanthin. mark for My Articles similar articles
Chemistry World
December 21, 2010
James Urquhart
Cellulose catalyst rewrites rules of attraction Chinese researchers have developed a magnetic solid acid catalyst that raises the prospect of efficiently converting biomass cellulose into useful chemicals, such as sugars for biofuel production. mark for My Articles similar articles
Chemistry World
August 13, 2007
Simon Hadlington
Nature Captured in a Test-Tube Two groups of researchers have demonstrated how a complex chain of reactions catalyzed by multiple enzymes can be reconstructed in the test tube to synthesize naturally occurring products that have potential therapeutic properties. mark for My Articles similar articles
Chemistry World
June 24, 2012
An Invaluable Resource In the new edition of "Organic Syntheses Based on Name Reactions: A Practical Guide to 750 Transformations," the authors deliver a comprehensive guide to named reactions in organic synthesis. mark for My Articles similar articles
Chemistry World
June 20, 2012
Rebecca Brodie
Faster removal of cigarette filters from the environment Filters can take years to degrade. Celanese Corporation has been working to develop a filter that contains a controlled-release organic acid to catalyse the hydrolysis of the filter material. mark for My Articles similar articles
Chemistry World
November 10, 2015
Elisabeth Ratcliffe
Eucalyptus bears both catalyst and biofuel Japanese researchers who have devised a method using eucalyptus trees that regenerates residue from the process into fresh catalyst. mark for My Articles similar articles