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Chemistry World January 25, 2013 Derek Lowe |
Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers? |
Chemistry World October 2009 |
Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions |
Chemistry World November 25, 2014 James Urquhart |
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. |
Chemistry World September 4, 2012 Derek Lowe |
Light in the Lab We organic chemists do terrible things to our molecules. How about dissolving the starting materials up in a flask, shining a light into the mixture and coming back later to find it transformed into your product? That's photochemistry. |
Chemistry World August 2007 Derek Lowe |
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. |
Chemistry World March 22, 2012 Ross McLaren |
Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule. |
Chemistry World August 2008 |
Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now? |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Reactive Reports December 2006 David Bradley |
Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database. |
Chemistry World October 23, 2013 Emma Eley |
Synthesis by sunlight Sustainable oxidation reactions can be performed with inexpensive and readily available photovoltaic cells |
Chemistry World February 2008 Dylan Stiles |
Column: Bench Monkey Cast a skeptical eye over new ideas in chemistry. |
Chemistry World August 22, 2014 Derek Lowe |
Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today. |
Chemistry World April 2007 Derek Lowe |
Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort? |
Chemistry World April 25, 2014 Derek Lowe |
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. |
Chemistry World July 22, 2015 James Morey |
Organic synthesis: state of the art -- 2011--2013 This book would be ideal for those needing to be on top of the literature in synthetic organic chemistry, but who don't have the time to read the ever-increasing body of pertinent articles. |
Chemistry World November 2007 Derek Lowe |
Column: In the Pipeline Chemists are finally going with the flow. |
Chemistry World August 16, 2009 Tom Bond |
Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis. |
Reactive Reports Issue 60 David Bradley |
Mark Leach Interview with the owner of Meta-Synthesis, a company aimed to reveal the inner secrets of chemistry to as wide an audience as possible. |
Chemistry World October 12, 2015 Emma Stoye |
Chemistry Nobel laureate Richard Heck dies Richard Heck, the organic chemist who shared the 2010 chemistry Nobel prize with for developing palladium-catalyzed cross coupling reactions, has died aged 84. |
Chemistry World July 10, 2013 Karl Collins |
An 'Aye' for details Today, using methods developed by masters of their trade, the modern greats of total synthesis demonstrate that almost any molecule can be prepared given time and effort. |
Information Today May 5, 2011 Robert E. Buntrock |
SciPlanner: Latest Addition to the CAS Suite of Programs In over a century of existence, Chemical Abstract Service has become the premier source of chemical information. |
Chemistry World September 30, 2009 Simon Haddlington |
Porous networks trap reactive intermediates Chemists in Japan have shown how it is possible to take sequential x-ray snapshots of chemical reactions taking place within molecular-sized 'reaction chambers', capturing the crystal structures of short-lived reactive intermediates. |
Chemistry World June 19, 2013 John Hayward |
Science of synthesis workbench edition: water in organic synthesis If a chemist is looking to do chemistry in (or on) water at the bench, Water in organic synthesis by Shu Kobayashi will be their guide. |
Chemistry World November 2010 |
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. |
Chemistry World April 10, 2008 Mark Peplow |
'Pot-in-a-Pot' Technique Makes Impossible Cascade Reactions Easy A simple technique that nests a series of reaction vessels could help chemists avoid the tedium and expense of purifying organic compounds after each step of a long synthesis. |
Chemistry World September 20, 2007 Lewis Brindley |
New Catalyst Rings the Changes Organic chemists in the US have developed a method to control the stereochemistry of a useful intramolecular Diels-Alder reaction. |
Reactive Reports Issue 45 |
Star Picks Chemistry Web sites: Chemists Celebrate Earth Day: Resources... Doing Chemistry... Chemistry Question... |
Chemistry World February 6, 2011 Laura Howes |
Cells as test tubes Chemists have used living cells as test tubes to carry out chemical reactions never before seen within living cells. |
Chemistry World August 22, 2012 Philip Ball |
The automatic chemist Bartosz Grzybowski of Northwestern University -- who has already established himself as one of our most inventive chemists -- has unveiled a 'chemo-informatic' scheme, Chematica, that can stake a reasonable claim to being paradigm-changing. |
Chemistry World July 17, 2014 Karl Collins |
Organic chemistry: a mechanistic approach Aimed at undergraduate chemistry students, this relatively succinct text begins with the fundamentals of molecular structure and introduces the concept of molecular orbitals early. |
Chemistry World July 9, 2012 Phillip Broadwith |
'Molecular cobra' turns C-H to C=C A reagent developed by US chemists can selectively introduce synthetically useful C=C double bonds into unactivated carbon chains, guided by an activating group attached to a nearby oxygen or nitrogen atom. |
Chemistry World March 2012 |
Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug |
Chemistry World September 9, 2011 James Mitchell Crow |
High-throughput catalyst screening for the masses Using nothing more than the standard chemistry lab equipment, researchers in the US have successfully turned the discovery of new catalytic reactions into a high-throughput process. |
Chemistry World June 2011 |
Column: Totally Synthetic I've never heard of the Polonovski-Potier reaction, the keystone of a remarkable synthesis by a team led by Tohru Fukuyama at the University of Tokyo, Japan. |
Chemistry World February 2, 2012 Philip Robinson |
Ultrafast NMR shows the way Chemists have created an ultrafast NMR technique that can 'watch' how chemical reactions occur in real time. They've used the technique to follow the formation of pyrimidines from carbonyls and even identified new intermediates never before thought to be part of the reaction. |
Chemistry World November 3, 2008 Simon Hadlington |
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? |
Chemistry World March 20, 2008 James Mitchell Crow |
Surfactants Help Reactions Work in Water Scientists have discovered a surfactant that allows the catalytic organic reactions commonly used to assemble organic structures such as drug molecules to be run in water. |
Chemistry World December 5, 2012 Phillip Broadwith |
Chemical reactions in hot water Chinese and Japanese chemists have highlighted hot water's ability to promote unexpected reactions without any other reagents or catalysts. The work should expand our understanding of how to harness the physicochemical properties of water to potentially replace more complex reagents and catalysts. |
Chemistry World March 2011 Paul Docherty |
Column: Totally Synthetic Discovered independently by two chemists in the 1870s, it's remarkable that 140 years later, science is still tweaking and improving the aldol reaction. |
Information Today December 16, 2010 |
CAS Introduces SciFinder Enhancements The enhancements will accelerate researchers' workflow and are especially valuable for synthetic chemists and other researchers who are engaged in lab preparations and synthesis planning. |
Reactive Reports Issue 49 |
Star Picks Chemogenesis is an e-book that goes in depth into chemical reactions and reactivity... Check out the Wiki books on chemistry for an open source chemistry textbook... |
Chemistry World July 14, 2009 Phillip Broadwith |
Multicomponent reactions step up a gear Dutch chemists have taken multicomponent reactions to the next level, combining a total of eight different starting materials in a single flask, bringing together three different multicomponent reactions and making nine new bonds in a single step. |
Chemistry World October 3, 2013 Laura Howes |
Twisting molecules for faster reactions Physical chemists in Germany and Switzerland have combined two different techniques to investigate the reactivities of different conformers -- and found one reaction that went 50% faster for one conformer over the other. |
Chemistry World September 23, 2013 Karl Collins |
The portable chemist's consultant The portable chemist's consultant from Phil Baran's laboratory at the Scripps Research Institute in California challenges the concept of a 'textbook' by providing a progressive, multimedia textbook application. This is the future of scientific textbooks. |
Chemistry World April 4, 2013 Phillip Broadwith |
A solution to fluoronium riddle The first evidence for hypervalent fluorine cations, or fluoronium ions, in solution has been found by US chemists. |
Chemistry World November 28, 2013 |
Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity. |
Chemistry World December 17, 2012 Patrick Walter |
RSC acquires rights to Merck Index The Royal Society of Chemistry has acquired the rights to the 'bible' of chemistry, the Merck Index, familiar around the world to medicinal chemists and drug discovery scientists. |
Chemistry World February 20, 2013 Amy Middleton-Gear |
Ohmic heating for efficient green synthesis Portuguese scientists have developed a new ohmic-heating reactor for organic syntheses on water, or chemistry using an aqueous suspension of the reactants. |
Chemistry World October 1, 2013 Eleanor Merritt |
New software for creating green solvents Scientists in France have developed a computer-assisted organic synthesis program to design sustainable solvents from bio-based building blocks. |
Chemistry World January 13, 2011 Sarah Corcoran |
Unclogging the problems of flow chemistry US scientists have found a way to stop solid byproducts clogging channels in continuous flow reactors, a problem that has hampered their progress for use in manufacturing pharmaceuticals. |