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Chemistry World February 19, 2010 Simon Hadlington |
Forcing stereoselectivity on reactive cations Chemists in the US have devised a dual catalyst strategy to tame the highly reactive iminium ion to give a high degree of stereochemical control over subsequent reactions of the ion. |
Chemistry World September 12, 2010 Simon Hadlington |
Isotope effect seen on single molecule The isotope effect - where the rate of a reaction is altered depending on the presence of a given isotopic atom in the reactant - is a key tool for elucidating reaction mechanisms |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World October 2009 |
Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions |
Chemistry World July 17, 2014 Karl Collins |
Organic chemistry: a mechanistic approach Aimed at undergraduate chemistry students, this relatively succinct text begins with the fundamentals of molecular structure and introduces the concept of molecular orbitals early. |
Chemistry World January 10, 2008 Jonathan Edwards |
Textbook Reaction Has a Subtle Twist The SN2 bimolecular nucleophilic substitution, a textbook reaction fundamental to organic synthesis, has a subtle twist, according to researchers. |
Chemistry World July 13, 2015 Philip Ball |
First snapshot of elusive intermediate supplies surprise A team near Zurich in Switzerland, has been able to take a single-molecule snapshot of an intermediate in a common class of organic reactions. |
Chemistry World November 15, 2011 Kate McAlpine |
Shedding light on ultracold reactions in space Two teams of researchers in the US and Europe have shown that light can play a bigger role than expected in the nascent field of ultracold atom-ion interactions. |
Chemistry World January 25, 2007 Richard Van Noorden |
Water Surprise for Atmospheric Scientists Lone water molecules can catalyze reactions between atmospheric gases, scientists have confirmed, throwing a wrench in the works of supposedly simple atmospheric chemistry. |
Chemistry World March 22, 2012 Ross McLaren |
Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule. |
Chemistry World November 25, 2014 James Urquhart |
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. |
Chemistry World December 5, 2012 Phillip Broadwith |
Chemical reactions in hot water Chinese and Japanese chemists have highlighted hot water's ability to promote unexpected reactions without any other reagents or catalysts. The work should expand our understanding of how to harness the physicochemical properties of water to potentially replace more complex reagents and catalysts. |
Chemistry World September 3, 2008 Lewis Brindley |
Hydroxide argument settled Scientists in Germany say they have settled an argument over how hydroxide ions travel quite so quickly through water, after finding evidence that they can donate a weak hydrogen bond. |
Chemistry World June 23, 2009 James Urquhart |
Smallest acid droplet formed Scientists in Germany have observed a single molecule of HCl dissociating into its component ions in water - and have discovered that just four water molecules are needed for complete dissociation of the acid. |
Chemistry World November 13, 2008 Hayley Birch |
Reactions Studied by Stop Motion Japanese and Israeli scientists have developed a technique that can track whole-molecule changes that occur during extremely rapid reactions. |
Chemistry World January 11, 2013 Marie Cote |
Following her passion Veronique Gouverneur is professor of chemistry at the University of Oxford, UK. She investigates fluorine chemistry and is working on developing novel synthetic methodologies for the preparation of fluorinated targets. |
Chemistry World September 12, 2013 Andy Extance |
Sulfur difluoride dimer exposes bonding strangeness Calculations on unusual bonding in the sulfur difluoride dimer FSSF 3 have provided evidence to help explain why some compounds don't follow long-established chemical rules. |
Chemistry World September 28, 2015 Karl Collins |
A witches' brew for trifluoromethylation Trifluoromethylating phenols is one example of a reaction that would be incredibly useful when attempting to tune the chemical and biological properties of molecules for pharmaceutical and agrochemical research. |
Chemistry World February 28, 2008 James Mitchell Crow |
Chloride Ions in a Bind Chemists in the US have designed a donut-shaped molecule that tightly binds negatively-charged chloride ions. |
Chemistry World July 11, 2012 Neil Withers |
Fluorine Finally Found in Nature Traces of elemental fluorine, F 2, have been found in calcium fluoride minerals by German chemists, who suggest that it's produced by uranium also found in the rock. |
Chemistry World March 2012 |
Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug |
Chemistry World July 10, 2013 Mark Peplow |
The nonclassical cation: a classic case of conflict In July, the last, incontrovertible piece of evidence finally arrived: an unambiguous crystal structure of the capricious cation. It crowns a chemical odyssey that has spanned six decades. |
Chemistry World November 3, 2008 Simon Hadlington |
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? |
Chemistry World June 11, 2008 Simon Hadlington |
Houdini Molecule Escapes Energy Trap A team of international chemists has captured and caught on camera a small, elusive molecule that has previously never been seen. |
Chemistry World November 12, 2014 Iain A Smellie |
Organic chemistry: structure, mechanism and synthesis This book contains all the key concepts one would expect in a good core organic chemistry textbook. The content also extends towards biochemistry and molecular biology. |
Chemistry World November 2007 Derek Lowe |
Column: In the Pipeline Chemists are finally going with the flow. |
Reactive Reports Issue 60 David Bradley |
Mark Leach Interview with the owner of Meta-Synthesis, a company aimed to reveal the inner secrets of chemistry to as wide an audience as possible. |
Chemistry World April 28, 2011 Simon Hadlington |
New method for aromatic coupling Chemists in Switzerland have developed a way to couple aromatic rings through the Friedel-Crafts mechanism - something many people would have believed impossible. |
Chemistry World October 15, 2012 Melissae Fellet |
Synthesis by mass spectrometry Chemists have used mass spectrometry, commonly used to analyze molecules, to synthesize them on the microscale. |
Chemistry World September 26, 2012 Derek Lowe |
Under pressure Someone interviewing for a synthetic chemistry position had better know his or her organic chemistry. It's fair to ask questions that will make sure of that. But does a candidate need to know the curly-arrow details of reactions that they'll never run? |
Reactive Reports Issue 45 |
Star Picks Chemistry Web sites: Chemists Celebrate Earth Day: Resources... Doing Chemistry... Chemistry Question... |
Chemistry World April 25, 2014 Derek Lowe |
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. |
Chemistry World April 2009 Martin & Moss |
The changing shape of chemistry, 1998 to 2008 There is much more variety, choice and diversity in modern undergraduate chemistry, but at what price? |
Chemistry World April 28, 2009 Jon Cartwright |
Metal ions give rise to threaded molecules Chemists in France have developed a simple method to synthesize tricky '[3]rotaxane' molecules for potential applications in intelligent materials and molecular machines. |
Chemistry World October 12, 2011 Joanne Thomson |
Hot Chemistry Temperature played a crucial role in David MacMillan's decision to study chemistry. |
Chemistry World December 14, 2012 Gan Shermer |
Organic chemistry Textbook of Organic Chemistry by C. Pillai is aimed at undergraduate chemistry students who already have a basic knowledge of organic chemistry. |
Chemistry World August 2007 Derek Lowe |
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. |
Chemistry World June 10, 2010 Phillip Broadwith |
A green and salty chiral catalyst An efficient, chiral, salt-based hypervalent iodine catalyst has been discovered by Japanese chemists that could replace toxic metal catalysts without generating the waste or explosion risks associated with hypervalent organo-iodine complexes. |
Chemistry World August 15, 2011 Simon Hadlington |
Trifluoromethylation Made Easy US researchers have discovered a simple, low-cost way to add fluorine atoms to heteroaromatic rings. |
Reactive Reports Issue 63 David Bradley |
Chemists Go Round the Bend Chemists often think of molecular wires as "shape-persistent" rods with limited flexibility, but researchers have now shown that molecular wires can be bent into ring shapes. |
Chemistry World November 11, 2009 James Urquhart |
Structural snapshots of complex molecules US researchers have pioneered a new spectroscopy technique to uncover the precise sequence of atomic movements and structural changes that occur during complex chemical transformations. |
Chemistry World October 16, 2006 Michael Gross |
Brief Encounter Observing fleeting interactions between molecules in solution requires extremely sophisticated methods. NMR spectroscopists have now developed tools that let them watch the transient encounter between two proteins before a well-defined complex is formed. |
Chemistry World February 18, 2010 Hayley Birch |
First sugars needed silicates to survive Earth's first complex sugars could have formed with a little help from silicate ions, according to a new study by US chemists. |
Chemistry World June 23, 2011 Simon Hadlington |
Breaking the carbon-fluorine bond US chemists have discovered a new way to break the bond between carbon and fluorine atoms - the strongest carbon bond there is. |
Chemistry World September 28, 2010 Lewis Brindley |
Helium nanodroplets host ion analysis Chemists have developed a sensitive new infrared spectroscopy method that analyses molecular ions by capturing them in nanosized bubbles of freezing helium. |
Chemistry World January 25, 2013 Derek Lowe |
Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers? |
Reactive Reports November 2007 David Bradley |
Organic Uranium The first ever uranium methylidyne molecule has been synthesized by US chemists despite the reactivity of the heavy, heavy metal. |
Chemistry World November 21, 2011 David Bradley |
Zombie reaction returns from the dead An oscillating reaction that apparently stops after 10 hours, but is then resurrected spontaneously several hours later, has been discovered by a group of chemistry students at the Mito Dai-ni senior high school in Ibaraki, Japan. |
Chemistry World May 25, 2007 Richard Van Noorden |
Keeping it Green Some chemistry enthusiastically labeled as green may be nothing of the kind, warn researchers who worry that mediocre -- if well-meaning -- science is damaging their subject. |
Chemistry World August 17, 2009 James Urquhart |
New method for fluorinating compounds Fluorine atoms are incorporated into aromatic organic compounds for many reasons, including their ability to increase metabolic stability, solubility and bioavailability. |