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Information Today June 6, 2005 Miriam A. Drake	A Cauldron Bubbles: PubChem and the American Chemical Society A freely accessible public database of chemical information, produced by a division of the U.S. National Institutes of Health (NIH), is at the center of a controversy over publicly subsidized data competing with commercial information providers.
Pharmaceutical Executive February 1, 2011 Jill Wechsler	The Building Block of Drug Discovery With Francis Collins now calling the shots at NIH, will be be able to deliver on the innovations behind the genome?
Chemistry World April 20, 2009 James Urquhart	New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought.
Chemistry World May 31, 2009 Nina Notman	The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used.
Reactive Reports Issue 53 David Bradley	Interview with Steve Bryant This research scientist talks about how and why PubChem was started, what it hopes to achieve, and how it is addressing some of the problems that have arisen since its inception.
Chemistry World October 2010	Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery
Chemistry World December 19, 2011 Rebecca Trager	US agencies collaborate to test 10,000 chemicals A high-speed robotic screening system jointly initiated by three key US health agencies began testing more than 10,000 chemical compounds for potential toxicity on 7 December.
Bio-IT World July 2005 Maureen McDonough	Genedata Software Plays Role in NIH Roadmap The NIH Chemical Genomics Center (NCGC) will use Genedata's Screener software system to collect and analyze data generated from its small-molecule library project. The NCGC is the first component of the NIH Roadmap to deliver new chemical tools for biomedical research.
Chemistry World May 2010 Derek Lowe	Column: In the pipeline The author wonders whether tagging molecules with fluorescent labels for assay is like tracking the members of a shoal of fish by tying each one to a whale. In the pharmaceutical business, our work absolutely lives and dies by assay results.
Chemistry World September 29, 2015	Navigating chemical space How big is chemistry? I don't mean how important is it, or how many people do it, but rather, how many molecules are there that we could make?
Chemistry World May 19, 2010 Rebecca Trager	NIH spends $1 billion on research construction projects The US National Institutes of Health has awarded $1 billion ( 700 million) to universities and medical centers across the country for the construction or upgrading of scientific research laboratories.
Chemistry World September 13, 2012 Andy Merritt	Chemical biology comes of age Historically strongest in the US, chemical biology has become increasingly important worldwide, but for many years researchers at the chemistry -- biology interface have struggled to establish their discipline
Bio-IT World February 10, 2003 Malorye Branca	Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic.
Reason June 2005 Kerry Howley	Scientists for Sale Innovation vs. ethics: Scientists at the NIH have discovered many things over the years, but evidently they haven't yet found a way to balance innovation and objectivity.
Chemistry World April 2011	Molecular Obesity is Weighing Down Drug Discovery Medicinal chemistry's quest for potent drug candidates has resulted in molecules that are too large and too lipophilic for their own good.
Bio-IT World February 2006	News Blast Franklin Award... Improved Sensitivity... Discovery Tag Team... NIH Screening Begins...
BusinessWeek June 13, 2005 John Carey	The NIH's Roadmap for Research Charting the human genome was just the beginning. Now the focus is creating pathways that will lead to practical applications.
Chemistry World May 20, 2015 Katrina Kramer	Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs.
Bio-IT World September 2006 Kevin Davies	Pfizer's Global Survey of Pharmacological Space The pharma blends knowledge, computational chemistry and research informatics to build a unified database. Gathering all the data in one place offered greater control for indexing and data retrieval and management, enabling Pfizer scientists to perform global mapping.
Chemistry World December 24, 2015 Rebecca Trager	US research agencies finally get their new budgets The US fiscal year 2016 appropriations, signed by President Obama on 18 December, provide $148.6 billion for federal research and development, an increase of 8.1% above current levels
Chemistry World January 20, 2014 David Bradley	Molecular librarians create druglike collections Finding biologically active small molecules with pharmaceutical potential is a bittersweet process. Now, a new approach to building libraries of diverse alkaloid-type structures has been developed by US chemists.
Chemistry World April 14, 2011 Sarah Farley	Fish in chips: growing embryos in microfluidic systems Scientists in the Netherlands and the UK have shown for the first time that an animal embryo can develop in a microfluidic environment.
Chemistry World October 15, 2014 Rebecca Trager	Quotas proposed to back younger US researchers A US politician's plans to introduce quotas to ensure that the National Institutes of Health's grants go to younger researchers is receiving opposition from somewhat surprising quarters -- science advocacy groups.
Chemistry World January 2012	Cultivating collaboration A new network aims to bring the power of interdisciplinary innovation to bear on global food issues.
Chemistry World January 2012	Rising interest in compound bank David Fox argues for the creation of a centralized repository for small molecules to harness research efforts in drug discovery
Chemistry World April 2, 2009 Ned Stafford	Fluorescent probes take screening to next level Researchers have developed a new high-throughput screening technique that could shed light on the biochemical activities of numerous proteins about which little is currently known.
ONLINE Sep/Oct 2007 Svetla Baykoucheva	A New Era in Chemical Information: PubChem, DiscoveryGate, and Chemistry Central How the emergence of PubChem, DiscoveryGate and Chemistry Central are changing the field of chemical information.
Chemistry World March 1, 2010 Rebecca Trager	US launches new regulatory science program Two major US government agencies have partnered to create a new regulatory science program to ensure better integration between cutting edge science and regulatory processes in assessing new medical products or compounds flowing from biomedical research.
Bio-IT World April 15, 2003 Mark D. Uehling	Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials.
Chemistry World October 15, 2008 Simon Hadlington	Long-life light illuminates cells The new dye, based on platinum, will carry on emitting light long after any interfering 'autofluorescence' from naturally occurring molecules in the cell has fizzled out.
Bio-IT World December 15, 2003 Malorye A. Branca	Scenes from a Cell Breakthroughs are making cell-based screening faster, easier, more powerful.
Chemistry World July 21, 2015 Ida Emilie Steinmark	Expert wiki to expose low-quality chemical probes After numerous examples of chemical probes ruining otherwise good research, the new project is looking to address the circulation of inferior probes, misuse of them and misleading studies.
Chemistry World March 14, 2008 Rebecca Trager	Tight us Budget Hits Chemistry Research The disappointing budgets allocated to US government science agencies are beginning to cut into chemistry.
Chemistry World February 5, 2008 Rebecca Trager	Bush Budget Proposal Backs Physical Sciences US President George Bush wants to get the budget for physical sciences research back on track, but biomedical research could suffer in his budget proposals for 2009.
Reactive Reports Issue 58	ID Tags for Teenage Molecules One academic team has developed a logical technology that allows them to generate millions of unique tags to track sub-microscopic objects.
Chemistry World December 11, 2008 Saffina Rana	EU coordinates research on measurement standards A new European metrology research program with an overall budget of at least 400 million could be underway by the end of 2009.
Pharmaceutical Executive October 1, 2011 Jill Wechsler	Guiding a Revolution in Science Francis Collins led the genomic revolution as director of the International Human Genome Project and director of the National Human Genome Research Institute (NHGRI) at the NIH from 1993 to 2008.
Chemistry World January 22, 2008 Rebecca Trager	NIH Battles Publishers Over Open Access The NIH has published controversial new rules that is sparking a showdown with publishers, including the American Chemical Society.
Bio-IT World August 18, 2004 Kevin Davies	In Praise of Chemical Diversity How to build better small-molecule libraries.
Information Today September 13, 2004 Barbara Quint	NIH Requires Open Access for Its Funded Medical Research With the NIH's decision, the fast-paced open access movement has picked up even more momentum.
Chemistry World November 2011 Derek Lowe	Column: In the Pipeline In recent years there's another class of 'unknown' compounds that's become more prominent than ever: the ones you can buy from the chemical catalogues.
The Motley Fool August 14, 2007 Brian Orelli	Drugmaker Growth Without the FDA Do you have one of those stomachs that just can't take the ups and downs of clinical trial data and FDA approval decisions? Buy stocks in the companies that support the drug makers.
Reactive Reports May 2007 David Bradley	Meeting of Molecular Movie Stars New footage confirms Linus Pauling's theory of chemical bonding proposed half a century ago, and could help explain molecular recognition processes important throughout supramolecular chemistry and molecular biology.
Chemistry World March 12, 2015 Matthew Gunther	Chemical building blocks produce a wellspring of organic molecules Scientists in the US have developed an automated platform to create small organic molecules from a set of simple of chemical building blocks.
Chemistry World January 7, 2008 Rebecca Trager	US Science Budget Fails to Deliver Although the 2008 budget has proved disappointing to the US science community, a light is on the horizon.
Chemistry World September 25, 2009 Rebecca Trager	US budget bears good news for chemistry President Obama's budget proposal for fiscal year 2010 - due to start 1 October - represents very good news for chemical science and for the general research community.
Chemistry World July 6, 2012	Protein power Tom Muir, professor of chemistry and molecular biology, Princeton University, US, is an expert in protein engineering and its application to studying cellular signalling networks.
Chemistry World October 25, 2010	Dual Purpose Dyes Offer New Imaging Options US researchers have developed a new series of combined fluorescent and chemiluminescent dye compounds that can be stored at low temperatures and then activated to release near infrared light when warmed to body temperature.
HHMI Bulletin Nov 2011 Sarah C. P. Williams	Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems.
Chemistry World October 28, 2014 Derek Lowe	Chemical space is big. Really big. We are not going to run out of interesting and useful structures, and the uses that they could be put to are probably also beyond our imagining. In chemical space, we really do have an effectively endless frontier.