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Chemistry World November 3, 2008 Simon Hadlington |
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? |
Chemistry World December 20, 2007 Richard Van Noorden |
Off-the-Peg Organic Synthesis Goes Commercial Chemists have created an efficient way to make small molecules by repeatedly using just one coupling reaction to clip together pre-prepared chemical fragments is going commercial. |
Chemistry World May 20, 2015 Katrina Kramer |
Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs. |
Chemistry World October 10, 2010 Andy Extance |
DNA strides into organic synthesis US scientists have used a DNA walker to synthesise an organic molecule in a series of steps, without intervention, for the first time. |
Chemistry World November 24, 2006 Richard Van Noorden |
Cooking up Nano-Fusilli Here's a new twist on nanotubes: chemists have found a set of organic molecules that spontaneously assemble themselves into a helical spiral with a hollow core. |
Chemistry World October 2011 Paul Docherty |
Column: Totally Synthetic Antioxidants are not only found in human cells, but also in bacterial cell walls - and a good example is synechoxanthin. |
Chemistry World April 19, 2012 Andy Extance |
Polymers perform non-DNA evolution Scientists have found that six polymer alternatives to DNA can pass on genetic information, and have evolved one type to specifically bind target molecules. |
Technology Research News June 29, 2005 |
Self-assembly: the natural way to make things In biology, there are a few different ways DNA molecules can be replicated and combined. |
Technology Research News January 14, 2004 |
Hardy molecule makes memory In what may mark an advance in the quest for ever-higher data-storage density, researchers from the University of California have shown that a type of porphyrin molecule holds up under temperatures as high as 400 degrees Celsius and after being written to and read from trillions of times. |
Reactive Reports May 2007 David Bradley |
Meeting of Molecular Movie Stars New footage confirms Linus Pauling's theory of chemical bonding proposed half a century ago, and could help explain molecular recognition processes important throughout supramolecular chemistry and molecular biology. |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Wired Erin Biba |
Molecular Frameworks, the Building Blocks of All Life The world is complicated, but not as complicated as you might think. Most organic molecules derive from a few relatively simple architectures. |
Bio-IT World August 18, 2004 Kevin Davies |
In Praise of Chemical Diversity How to build better small-molecule libraries. |
Chemistry World March 3, 2013 James Urquhart |
Polymer production line runs on DNA US researchers have developed a purely chemical and enzyme-free system that can build synthetic polymers using DNA as a template. |
Chemistry World August 26, 2008 |
Photonic crystal drug detective A new high-throughput screening system based on photonic crystals could quickly and cheaply detect molecules that disrupt binding between proteins and DNA. |
Chemistry World May 12, 2011 Jon Cartwright |
'Chemical soldering' heralds single molecule electronics Scientists in Japan and Switzerland have demonstrated how to wire up single molecules with conductive nanowires. |
Chemistry World January 21, 2011 Russell Johnson |
Jump starting prebiotic photochemistry Light activated reactions of organic molecules in fatty acid membranes offers a plausible method for energy transfer and storage in prebiotic systems, claim US scientists. |
Chemistry World October 1, 2013 Eleanor Merritt |
New software for creating green solvents Scientists in France have developed a computer-assisted organic synthesis program to design sustainable solvents from bio-based building blocks. |
Chemistry World July 14, 2011 Simon Hadlington |
Natural Products Made Via a Single Parent Molecule Chemists in the US have taken inspiration from nature to devise a new concept for rapidly and efficiently synthesising structurally diverse natural products from a single common precursor. |
Chemistry World November 28, 2013 |
Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity. |
Reactive Reports Issue 71 David Bradley |
DNA Nanorings A simple approach to making rigid DNA nanorings with tailor-made functionality has been developed by Michael Famulok and his team |
Chemistry World December 8, 2008 Hayley Birch |
Meteorites hitting oceans may have kick-started life Japanese scientists have done laboratory experiments to test the idea. |
Chemistry World March 8, 2010 Lewis Brindley |
Molecular midwives helped birth of DNA 'Molecular midwives' - are compounds that played a crucial role in combining small nucleotide fragments into the first genetic polymeric material. |
Chemistry World February 28, 2010 Jon Cartwright |
Reactions on DNA origami watched with AFM Chemists in Denmark have for the first time imaged chemical reactions on a DNA origami scaffold so that they can precisely attach single molecules, involving atomic force microscopy. |
Chemistry World September 29, 2015 |
Navigating chemical space How big is chemistry? I don't mean how important is it, or how many people do it, but rather, how many molecules are there that we could make? |
Technology Research News March 23, 2005 |
Nanowires track molecular activity Researchers from Harvard University have found a way to use transistors made from silicon nanowires to gain information about how small molecules bind to proteins. |
Chemistry World November 8, 2013 Rowan Frame |
Big data approach to solar cells After 150 million theoretical calculations, scientists at Harvard University in the US reveal results that could cut down the time and cost of experimental tests to find better organic electronic materials for solar cells. |
Chemistry World March 29, 2012 Simon Hadlington |
Seeds of life incubated in proto-planetary nurseries New findings imply that the organic chemistry required to produce the necessary molecules for life is part of the normal processes of planet formation. |
Chemistry World August 3, 2007 Simon Hadlington |
Making Light Work of Drug Release UK researchers have borrowed a technique from organic synthetic chemistry to develop a new type of drug-release system that is activated by light. |
Technology Research News November 3, 2004 Kimberly Patch |
DNA in nanotubes sorts molecules Researchers have made a synthetic membrane that recognizes certain biochemical molecules and allows them to pass through. The method could be used to make biological sensors like those needed for genetics research, and to sort biological molecules, |
Chemistry World June 10, 2010 Simon Hadlington |
Elusive intermediate snared Chemists in Germany have succeeded in trapping an elusive intermediate involved in a key synthetic reaction catalysed by an organic molecule. |
Chemistry World September 7, 2014 Michael Gross |
Bringing chemical synthesis to the masses The promise of a novel approach to building chemical libraries, which only requires simple building blocks in water, without any additional reagents or sample preparation, is inspired by nature. |
Chemistry World July 15, 2011 Laura Howes |
Cyclodextrin Dimer Becomes Synthetic Polymerase Chemists have made an artificial polymerase that doesn't need a metal catalyst or organic solvents and is more efficient than current bioinspired approaches. |
HHMI Bulletin Nov 2011 Sarah C. P. Williams |
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. |
Chemistry World October 8, 2013 Hayley Birch |
RNA mimic destined for synthetic genome US scientists have taken another step towards the goal of creating self-replicating molecules like those thought to have spawned life on Earth. The researchers made RNA-like polymers capable of copying short sections of genetic code that they suggest could act as genomes in synthetic cells. |
Chemistry World February 21, 2007 Simon Hadlington |
Organic Electricity Generator is Hot Stuff Researchers have successfully demonstrated the thermoelectric effect in an organic molecule. The findings open up the possibility of potential new energy sources, and also present a novel way for probing the electronic structure of molecular junctions. |
Chemistry World April 20, 2009 James Urquhart |
New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought. |
Chemistry World June 30, 2015 Jessie-May Morgan |
Space-like conditions give rise to metabolic precursors Mimicking interstellar conditions, a team of scientists at NASA has synthesized complex organic molecules thought to be necessary for the origin of life. |
Chemistry World October 14, 2015 Emma Cooper |
Calcium carbide replaces explosive acetylene in organic synthesis Scientists have replaced explosive acetylene with cheap and benign calcium carbide to make common small organic molecules in a safer, cheaper and more atom-economical way, and at scale. |
Chemistry World September 29, 2014 David Bradley |
Pick and mix macromolecules New ways are discovered to piece together pi-functional molecular building blocks to make a wide range of macromolecules. |
Chemistry World May 31, 2009 Nina Notman |
The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used. |
Chemistry World September 25, 2014 Simon Hadlington |
First interstellar sighting of a branched alkyl molecule The radiotelescope in Atacama, Chile, has found the first branched molecule ever seen in interstellar space |
Chemistry World February 13, 2011 Simon Hadlington |
First purely organic phosphor Scientists in the US have made a major advance in the development of novel light-emitting materials by designing the first purely organic phosphorescent compound. |
PC World February 1, 2002 Kuriko Miyake |
Olympus Unveils DNA Computer Rather than relying on a microprocessor, computer runs on reactions between fragments of DNA... |
Chemistry World June 1, 2010 Simon Hadlington |
Structural order gained over conducting polymer Scientists in Canada and the US have shown how it is possible to assemble ordered arrays of short chains of a commercially important conducting polymer on a metal surface. |
Geotimes January 2007 Carolyn Gramling |
The Color of Crinoids Scientists have discovered complex organic molecules still preserved within 350-million-year-old crinoid fossils. Because the molecules are slightly different from species to species, the find could offer a new way to track the creatures' evolution through time. |
Chemistry World February 2011 |
Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential |
Chemistry World July 2008 Kevin Rogers |
What future for small molecule therapy? Pharmaceutical companies overlook bench chemists at their peril |
Chemistry World June 23, 2015 Derek Lowe |
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. |
Chemistry World July 13, 2015 Philip Ball |
First snapshot of elusive intermediate supplies surprise A team near Zurich in Switzerland, has been able to take a single-molecule snapshot of an intermediate in a common class of organic reactions. |