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Technology Research News June 29, 2005 |
Self-assembly: the natural way to make things In biology, there are a few different ways DNA molecules can be replicated and combined. |
Chemistry World April 19, 2012 Andy Extance |
Polymers perform non-DNA evolution Scientists have found that six polymer alternatives to DNA can pass on genetic information, and have evolved one type to specifically bind target molecules. |
Chemistry World April 3, 2008 Lewis Brindley |
DNA Read in a Trice The prospect of treatments that are tailored to fit an individual's genetic makeup is a step closer thanks to technology unveiled by US scientists. |
Technology Research News March 24, 2004 |
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. |
Technology Research News June 15, 2005 Kimberly Patch |
DNA Machine Links Molecules Researchers have fashioned a nanomechanical device from DNA that can be programmed to align a series of molecules and fuse them together. The technique could potentially be used to put together designer polymers, encrypt information, and carry out computations. |
Chemistry World August 23, 2011 Josh Howgego |
Expanded genetic alphabet could spell out new genes Chemists have created an artificial genetic code capable of evolving to produce new genes. The code consists of six bases, rather than the standard four, and could form the basis of randomly mutating synthetic life. |
Chemistry World February 27, 2006 Michael Gross |
A DNA Switch for RNA Folding Researchers have equipped a large RNA domain with a DNA switch, which they say can fold or unfold the RNA molecule at will. |
Chemistry World September 23, 2009 Simon Hadlington |
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. |
Chemistry World October 8, 2013 Hayley Birch |
RNA mimic destined for synthetic genome US scientists have taken another step towards the goal of creating self-replicating molecules like those thought to have spawned life on Earth. The researchers made RNA-like polymers capable of copying short sections of genetic code that they suggest could act as genomes in synthetic cells. |
Technology Research News September 24, 2003 |
Glow shows individual DNA Researchers have made a type of artificial DNA of that glows when it combines with a specific sequence of natural DNA. In principle, the method could be used to develop DNA chips that directly sense individual DNA molecules. |
Chemistry World June 4, 2008 Simon Hadlington |
Man-made protocell hosts DNA synthesis US researchers have taken a step towards creating a synthetic cell in the laboratory that could resemble the first primitive stirrings of life on Earth. |
Chemistry World January 8, 2012 David Bradley |
The TNA world that came before the RNA one Once it was recognised that DNA is key to the molecular self-replication that underpins life, chemists have sought to understand the origins of this double-helical molecule in that primordial age. |
Science News September 21, 2002 Ivars Peterson |
DNA's Error-Detecting Code Chemist Donall A. Mac Donaill of Trinity College in Dublin, Ireland, has now shown that patterns inherent in the chemical makeup of DNA correspond to a digital error-detecting code. |
Technology Research News August 22, 2005 |
DNA Technologies The versatile DNA molecule has proven to be a powerful technological building block. Researchers have developed ways of combining DNA molecules that allow them to carry out computations in test tubes and create two-dimensional patterns and three-dimensional structures at the nanoscale. |
Technology Research News May 5, 2004 Kimberly Patch |
DNA Bot Targets Cancer Researchers from Israel have constructed a molecular-size computer that is programmed to find signs of cancer cells, and when they are present, dispense DNA molecules designed to eradicate those cells. |
Technology Research News November 3, 2004 Kimberly Patch |
DNA in nanotubes sorts molecules Researchers have made a synthetic membrane that recognizes certain biochemical molecules and allows them to pass through. The method could be used to make biological sensors like those needed for genetics research, and to sort biological molecules, |
Chemistry World October 13, 2015 Simon Hadlington |
DNA movement through motor proteins measured Researchers have adapted a method for DNA sequencing to measure directly and with exquisite sensitivity the movement of a single molecule of DNA as it is drawn through specialized motor proteins. |
Technology Research News December 3, 2003 |
Molecule does two-step Duke University researchers have found a way to make a molecule react only when it has been hit by two photons of ultraviolet light, making the molecule a controllable switch. The molecule could eventually be used in optical storage devices and in biochips. |
IEEE Spectrum March 2011 Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
Reactive Reports May 2007 David Bradley |
Meeting of Molecular Movie Stars New footage confirms Linus Pauling's theory of chemical bonding proposed half a century ago, and could help explain molecular recognition processes important throughout supramolecular chemistry and molecular biology. |
Technology Research News February 11, 2004 |
Scientists brew tree-shaped DNA Researchers from Cornell University have synthesized a new type of DNA that can be used as a nanotechnology building block. |
Chemistry World January 28, 2015 Emma Stoye |
Tiny volcanic cracks 'incubated' ancient DNA Tiny pores within volcanic rocks on ancient Earth may have provided the ideal conditions for replicating molecules, and could also have driven the evolution of longer and longer genetic sequences, researchers in Germany have shown. |
Chemistry World August 30, 2011 Laura Howes |
G-quadruplexes take the strain in cancer drug search A new single molecule technique can provide greater insight into the interactions between G-quadruplexes and small-molecule ligands. |
Science News April 8, 2000 Ivars Peterson |
Hiding in DNA ...This use of DNA molecules to hide secret messages won Viviana I. Risca of Paul D. Schreiber High School in Port Washington, N.Y., the top prize at this year's Intel Science Talent Search... |
Reactive Reports Issue 71 David Bradley |
DNA Nanorings A simple approach to making rigid DNA nanorings with tailor-made functionality has been developed by Michael Famulok and his team |
Chemistry World January 2012 |
DNA motors on With the relentless rise of DNA nanotechnology's popularity, Emma Davies explores the role chemistry has played in its success |
Chemistry World March 4, 2015 Thadchajini Retneswaran |
Computational chemists unpick adenine -- thymine bias A chemical model has been created to investigate the evolution of guanine -- cytosine coding regions and found that certain spontaneous mutations are more likely to arise at specific regions of DNA. |
Chemistry World March 12, 2015 Matthew Gunther |
Chemical building blocks produce a wellspring of organic molecules Scientists in the US have developed an automated platform to create small organic molecules from a set of simple of chemical building blocks. |
Chemistry World February 9, 2012 Jennifer Newton |
A new generation of tuberculosis drugs Scientists in India are targeting enzymes responsible for catalysing the formation of bonds to repair nicks in the phosphodiester backbone of DNA - called DNA ligases - to tackle the ever-growing health concern of multi-drug resistant bacteria. |
Chemistry World November 16, 2006 Simon Hadlington |
Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly. |
Chemistry World February 8, 2006 Jon Evans |
To Boldly go Where no Chemist Has Gone Before Studying the interactions between different molecular fragments is taking researchers to the uncharted regions of chemical space. |
Reactive Reports Apr/May 2005 David Bradley |
At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule. |
Chemistry World June 23, 2015 Derek Lowe |
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. |
Chemistry World November 16, 2011 Simon Hadlington |
Unlocking the secrets of DNA's stiffness Computational chemists believe they have solved one of the puzzles about the stiffness of DNA: how much of the molecule's rigidity is due to electrostatic forces and how much to its physical structure. |
Chemistry World May 12, 2011 Jon Cartwright |
'Chemical soldering' heralds single molecule electronics Scientists in Japan and Switzerland have demonstrated how to wire up single molecules with conductive nanowires. |
Chemistry World April 18, 2010 Simon Hadlington |
First DNA rotaxane Rotaxanes are dumbbell-shaped molecules encircled by a molecular hoop that can move unhindered along the axle, trapped by the bulky stoppers at either end. These could be useful components in molecular machines. |
Chemistry World January 31, 2008 Michael Gross |
A DNA Crane for Molecular Building Sites Researchers in Germany have developed a DNA-based crane that can pick up molecules from a depot and deposit them precisely at a target site. |
Chemistry World September 17, 2012 Ian Le Guillou |
Raising the curtain on single-stranded DNA Scientists have created microfluidic devices containing single-stranded DNA 'curtains' for the first time, allowing scientists to study its interactions with proteins in real time. |
Chemistry World October 31, 2008 Manisha Lalloo |
DNA-rewinding protein discovered US scientists have found an enzyme that rewinds sections of DNA whose strands have mistakenly come apart. |
Chemistry World July 4, 2010 Hayley Birch |
DNA sticks at flick of switch A new technique that sticks individual DNA molecules to a gold surface works at the flick of an electrochemical switch. |
Technology Research News December 3, 2003 Kimberly Patch |
DNA assembles nanotube transistor Scientists have caused a transistor to self-assemble from a test tube concoction of DNA, proteins, antibodies, carbon nanotubes and minuscule specks of silver and gold. The feat shows that it is possible to assemble the smallest of machines and electronic devices by harnessing DNA's properties. |
Chemistry World October 19, 2009 Simon Hadlington |
DNA stretching mystery solved A detailed understanding of the elastic properties of DNA can give scientists key insights into interactions of DNA and the proteins that carry out these manipulations. |
HHMI Bulletin February 2012 Sarah C. P. Williams |
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. |
Chemistry World February 11, 2015 James Urquhart |
'Early RNA' reactions characterized Researchers have shown how precursor nucleotide molecules could have self-polymerized without enzymes and subsequently given rise to the catalytic activity of the simplest, most ancient forms of RNA. |
Technology Research News April 23, 2003 Kimberly Patch |
DNA motor keeps cranking Researchers have been making DNA perform all sorts of shape-changing tricks in recent years, but the need to add pieces of DNA at every step has made it a bit of a stretch to call these molecules motors. A method that keeps the process humming changes things. |
Chemistry World May 7, 2014 Emma Stoye |
Bacterium survives unnatural DNA transplant The first organism that can grow and replicate with an unnatural base pair in its DNA -- giving the cell six nucleotides instead of the usual four -- has been created by scientists in the US. |
Chemistry World April 14, 2009 Hayley Birch |
DNA electronics a step closer Japanese researchers have improved the electrical conductivity of DNA through simple chemical modifications. |
Chemistry World October 19, 2015 Matthew Gunther |
The house that DNA built The 2015 chemistry Nobel prize was awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar for DNA repair. |
Scientific American June 2005 JR Minkel |
RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right. |
Chemistry World December 12, 2011 Simon Hadlington |
Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity. |