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Chemistry World August 3, 2006 Bea Perks	Sugar-Coated Antibodies The fate of the prey captured by our body's guardian antibodies can be determined by sugar molecules found on the antibody's surface. The news has come as a surprise to immunologists, who were unsure of these sugar molecules' exact role.
Chemistry World July 25, 2008 Olivia Walker	Engineered antibodies could cut chemotherapy risks US scientists have cut the side-effects of cancer treatment in animal trials by carefully controlling the number of drug molecules attached to the antibodies used for chemotherapy.
The Motley Fool August 31, 2011 Brian Orelli	Antibodies: They're Not Just for Fighting Infection Anymore Therapeutic antibodies have continued to evolve since the first, OKT3, was approved back in 1986. Biotech investors had better pay attention, lest the technology passes them by.
Chemistry World September 2010	Column: In the pipeline Derek Lowe considers the quandaries of living in the age of the kinase
Chemistry World March 9, 2012 Fiona McKenzie	Cleaning up antibodies for disease studies A polymer functionalized with boronic acid promises a cheap and quick way to purify antibodies for disease studies, according to scientists in China.
Chemistry World February 21, 2013 David Bradley	Copycat flags help aliens avoid mouse immune system Synthetic peptide flags added to therapeutic and diagnostic agents can trick the immune system into ignoring them, according to US researchers.
Chemistry World November 27, 2011 James Mitchell Crow	Artificial enzymes close in on nature A synthetic metalloprotein that approaches the catalytic performance of a natural enzyme, despite its stripped-down structure, has been developed by a team of chemists in the US.
Chemistry World June 23, 2015 Derek Lowe	Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example.
Chemistry World July 2010	Column: In the pipeline Derek Lowe ponders the possibility of phosphatase inhibitors
Chemistry World March 3, 2013 James Urquhart	Polymer production line runs on DNA US researchers have developed a purely chemical and enzyme-free system that can build synthetic polymers using DNA as a template.
Reactive Reports Issue 58	Anthrax Detector Researchers have developed a detector for anthrax spores based on a monoclonal antibody that recognizes a specific sugar on the bacterium. It might be possible to use this discovery to develop a passive immunization method.
Chemistry World July 8, 2010 Sarah Houlton	Antibodies spark HIV vaccine hopes These cross-reactive broadly neutralising antibodies bound to and neutralised more than 90 per cent of the HIV strains they were tested against.
Chemistry World January 6, 2010 Phillip Broadwith	Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain.
Chemistry World November 6, 2009 Phillip Broadwith	Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before.
Chemistry World January 7, 2014 Derek Lowe	Is there a drug for that? One hears a lot about the concept of 'druggability' in pharmaceutical research. If that concept has any meaning (and it probably does), then the implication is that there must be such a thing as 'undruggability'. So what does that look like?
Chemistry World October 14, 2008 Simon Hadlington	Enzymes hit with double punch US chemists have made a small molecule that simultaneously blocks two key enzymes involved in the growth of cancer cells.
Chemistry World August 13, 2009 Simon Hadlington	Forcing enzyme activity New research has shown that physically stretching an enzyme can trigger its activity - even when the active site is not hidden in a 'cryptic' position. Mechanical force may play a more important role in biological molecular systems than previously realized.
Chemistry World September 2, 2007 Simon Hadlington	Sweet Approach to Tackling Cancer A promising new 'slimline' cancer vaccine that triggers a powerful immune response against excessive sugar molecules has been unveiled by researchers.
Chemistry World February 17, 2013 Simon Hadlington	Enzyme nano-parcels sober up drunken mice Scientists in the US and China have invented a way to encapsulate teams of enzymes in a thin polymer shell. This enables the enzymes to carry out a series of sequential reactions within an enclosed space -- as happens in nature.
Chemistry World September 9, 2007 Simon Hadlington	Sugaring the Pill Researchers in the US have made a key advance in efforts to bolt sugar molecules onto natural products in the search for new drugs.
Chemistry World June 9, 2013 James Urquhart	Hairy proteins survive stomach trip Swiss researchers have discovered a way to stabilize enzymes in the digestive tract by linking polymers to the enzymes.
Chemistry World January 16, 2011 Hayley Birch	Antibodies could lead to MRSA vaccine US scientists have developed antibodies against a protein belonging to methicillin-resistant Staphylococcus aureus bacteria.
Chemistry World August 13, 2007 Simon Hadlington	Nature Captured in a Test-Tube Two groups of researchers have demonstrated how a complex chain of reactions catalyzed by multiple enzymes can be reconstructed in the test tube to synthesize naturally occurring products that have potential therapeutic properties.
Chemistry World February 2011	Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential
Chemistry World December 21, 2015 Katrina Kramer	BioAtla and Pfizer to collaborate on antibody research BioAtla and Pfizer will share expertise to develop tumor-targeting antibodies chemically bound to cytotoxic drugs.
Food Processing August 2007 Mark Anthony	Nutrition Beyond the Trends: Connecting the Dots on Enzymes Lactase -- an enzyme that splits lactose into its constituent sugars, glucose and galactose -- can make short work of the lactose intolerance problem.
Chemistry World September 4, 2006 Michael Gross	Antibodies in the Greenhouse Researchers have developed a way to produce molecules of the antibody class immunoglobulin G (IgG) in the leaves of ordinary tobacco plants.
Chemistry World September 3, 2009 Sarah Houlton	New HIV vaccine hope A team of scientists in the US has discovered two new antibodies that could lead to an HIV vaccine.
Chemistry World April 2, 2014 Megan Tyler	DVD diagnostics A pregnancy test based on standard DVD technology has the potential to be turned into a diagnostic platform that screens for abnormal pregnancies or even testicular cancer.
Chemistry World April 1, 2011 Hayley Birch	Nanoparticles help reveal hidden fingerprints A technique using gold nanoparticles in combination with antibodies has shown promising results for enhancing fingerprints that are over a week old.
Reactive Reports Issue 52 David Bradley	Microscopic Contact Lenses Make Sense Gel lenses, resembling microscopic contacts, could find a role in biosensors for analysis and diagnostics, according to researchers at the Georgia Institute of Technology.
Chemistry World October 2, 2012 Andrew Turley	Merck & Co $460m ion channel deal Merck & Co has struck a $460 million deal for rights to certain drug candidates developed by Belgian pharma company Ablynx. Merck will get rights to the monoclonal antibodies found to target a voltage gated ion channel.
Chemistry World March 6, 2008 Simon Hadlington	Synthetic Enzymes Designed by Computer Scientists in the US have designed and built an artificial enzyme from scratch.
Chemistry World September 24, 2007 Simon Hadlington	Viral Nanoreactor Captures Single Molecules Researchers in the Netherlands have created a biochemical nanoreactor by cracking open a virus, removing its contents then reassembling the virus's protein coat around a single molecule of enzyme.
Chemistry World January 17, 2014 Phillip Broadwith	Plug and play redox enzymes With the constant drive to make chemical synthesis ever cleaner, more energy-efficient and generate less waste -- both in research and industrial processes -- more and more chemists are looking to harness enzyme catalysis.
The Motley Fool October 1, 2008 Brian Orelli	3 Drugmakers With Multiple Shots on Goal Well-stocked pipelines could kick these drugmakers into super-high gear.
Chemistry World November 26, 2010 Rebecca Brodie	Printing on bioactive paper An enzyme printing process that prints the product of an enzyme-catalysed reaction, but not the enzyme molecule itself, has been designed by scientists in Australia to produce bioactive paper.
HHMI Bulletin February 2012 Sarah C.P. Williams	The Twists and Turns of Immunity Fred Alt has built a career making sense of the immune system -- specifically, the diverse antibodies that fight off invading molecules, from viruses to cancer cells to pollen.
Chemistry World July 10, 2013 Karl Collins	An 'Aye' for details Today, using methods developed by masters of their trade, the modern greats of total synthesis demonstrate that almost any molecule can be prepared given time and effort.