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Chemistry World November 25, 2009 Simon Hadlington	Virus shells traps multiple proteins Scientists in The Netherlands have devised a way to pack large numbers of proteins into the empty shell of a virus.
Chemistry World April 14, 2006 Simon Hadlington	Deciphering Hydrogen Tunnelling in Enzymes Researchers have thrown important new light on the phenomenon of hydrogen tunnelling in biological catalysts. The finding is likely to spark a debate among biochemists about the fundamental nature of enzymes.
Chemistry World November 26, 2010 Rebecca Brodie	Printing on bioactive paper An enzyme printing process that prints the product of an enzyme-catalysed reaction, but not the enzyme molecule itself, has been designed by scientists in Australia to produce bioactive paper.
Chemistry World September 12, 2010 Simon Hadlington	Isotope effect seen on single molecule The isotope effect - where the rate of a reaction is altered depending on the presence of a given isotopic atom in the reactant - is a key tool for elucidating reaction mechanisms
Chemistry World December 12, 2011 Simon Hadlington	Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity.
Chemistry World August 2, 2006 Bea Perks	Quantum Leap for Virus Trackers Glowing quantum dots are helping researchers study how viruses infect cells, and although the fluorescent nanoparticles have only been used on plant viruses so far, the technique could prove to be invaluable for drug development.
Chemistry World March 6, 2008 Simon Hadlington	Synthetic Enzymes Designed by Computer Scientists in the US have designed and built an artificial enzyme from scratch.
Chemistry World November 27, 2011 James Mitchell Crow	Artificial enzymes close in on nature A synthetic metalloprotein that approaches the catalytic performance of a natural enzyme, despite its stripped-down structure, has been developed by a team of chemists in the US.
Chemistry World August 13, 2009 Simon Hadlington	Forcing enzyme activity New research has shown that physically stretching an enzyme can trigger its activity - even when the active site is not hidden in a 'cryptic' position. Mechanical force may play a more important role in biological molecular systems than previously realized.
Chemistry World June 6, 2010 Philip Ball	Blood-like liquid protein formed A liquid form of the oxygen-binding protein myoglobin retains its biological function even though it seems virtually water-free, researchers have found.
Chemistry World March 16, 2006 Michael Gross	Plant Virus Fixed with Antennae Researchers have coupled a virus with redox-active molecules. Such particles could become useful in nanoelectronics, they claim.
Chemistry World August 29, 2007 Ananyo Bhattacharya	'Lost' Folate Enzyme Found After 30 Years US researchers have revealed the identity of an enzyme used by bacteria to make the essential B vitamin folate, 30 years after it was first isolated.
Chemistry World May 14, 2008 Simon Hadlington	Bird Flu's Drug Resistance Mapped UK scientists have shown exactly why a mutant version of the deadly bird flu virus H5N1 becomes resistant to the drug oseltamivir - marketed as Tamiflu.
Chemistry World January 6, 2011 Laura Howes	Using HIV against itself US researchers have developed a 'Trojan horse' molecule that uses HIV to trigger the release of a drug that destroys the virus.
Chemistry World December 6, 2006 Jessica Ebert	Structure of Key Influenza A Protein Revealed The crystal structure of a molecule important for the replication of the influenza A virus has been solved. Now that scientists know what the protein looks like they can design drugs that block its action and prevent viral spread through the body.
Chemistry World December 8, 2011 Sarah Farley	Capturing Compounds in Cages for Chemical Control Scientists from the UK have used a molecular capsule to control the reactivity of an organic compound.
Chemistry World March 20, 2007 Lionel Milgrom	Chemical Model Unlocks Key Enzyme's Secrets The precise workings of cytochrome c oxidase (CcO), an enzyme that is crucial for all aerobic life, have been unveiled.
Chemistry World November 26, 2012 Laura Howes	Protein coat prepares catalyst for cascades By protecting a transition metal catalyst with a protein coat, scientists have managed to couple up biocatalysts and chemical catalysts to perform a cascade reaction.
Chemistry World November 5, 2015 Emma Stoye	Unnatural nanoreactor puts click reaction in the spotlight A protein 'nanoreactor' that can monitor a click chemistry reaction at the level of single molecules has been created by adding an unnatural amino acid to a nanopore.
Chemistry World January 6, 2010 Phillip Broadwith	Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain.
Chemistry World August 26, 2014 Andy Extance	No-frills coats set a trend for designer viruses Dutch scientists have built a simple model of viruses' protective coats in an attempt to create viral mimics that could fight diseases, as opposed to causing them.
Chemistry World May 2, 2007 Michael Gross	Protein Printboard Chemists in the Netherlands have created nanoscale structures that can immobilize proteins with exquisite control over specificity, strength and orientation.
Chemistry World November 25, 2015 Philippa Matthews	'Superballs' can block infection by Ebola virus Molecular 'superballs' have been created that can stop viruses infecting cells.
Chemistry World July 15, 2010 Simon Hadlington	Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit.
Chemistry World October 27, 2006 Richard Van Noorden	Synthetic Origami Folds Like Natural Enzymes Researchers have synthesised a large organic molecule that folds up like a small protein, though its backbone is entirely non-biological. The achievement is a step along the path to producing truly synthetic enzymes in the laboratory.
Chemistry World April 21, 2010 Simon Hadlington	Methane oxidising enzyme mystery solved The finding could lead to a cost-effective and environmentally clean method of methanol production for fuel and feedstock.
Chemistry World February 3, 2010 Simon Hadlington	New 'hook' for reversibly binding molecules to proteins UK chemists have found a simple new 'hook' that allows molecules to be attached to proteins and later removed, something that is currently difficult to achieve.
Chemistry World January 17, 2010 Simon Hadlington	Sugars synthesised with help of promiscuous enzyme European researchers have discovered a new way to make synthetically elusive sugar molecules that could lead to novel vaccine candidates and other medically important compounds.
Chemistry World January 8, 2009 Victoria Gill	Breast cancer drug target crystallised The crystal structure of human aromatase, an enzyme that is a key drug target for treating breast cancer, has been solved by US scientists.
Chemistry World December 14, 2011 Kate McAlpine	Artificial intelligence for quantum chemistry Quantum chemical approximations don't always need to start from scratch, says an international team of researchers. Algorithms can now be used to predict the atomisation energy of huge numbers of molecules
Chemistry World March 15, 2007 Henry Nicholls	The Mother of All Enzymes Scientists have uncovered the three-dimensional structure of what might be biology's first enzyme. This sheds light on the chemistry at a key moment in the origin of life, they argue.
Chemistry World December 5, 2007 Ananyo Bhattacharya	Structural Snapshot Shows Monster Protein A structural snapshot of a protein capsule has revealed details of the largest cellular component ever imaged by x-ray crystallography.
Chemistry World September 9, 2007 Simon Hadlington	Sugaring the Pill Researchers in the US have made a key advance in efforts to bolt sugar molecules onto natural products in the search for new drugs.
Chemistry World November 16, 2006 Simon Hadlington	Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly.
Chemistry World October 11, 2009 Simon Hadlington	Diode breakthrough in molecular electronics Researchers from the US and Russia have shown how it is possible to measure the diode properties of a single molecule and how the orientation of the molecule between two electrodes can be controlled.
Technology Research News May 7, 2003	Researchers fill virus with metal One way to construct materials atom by atom is to conscript machinery nature has already devised.
Chemistry World April 2, 2009 Ned Stafford	Fluorescent probes take screening to next level Researchers have developed a new high-throughput screening technique that could shed light on the biochemical activities of numerous proteins about which little is currently known.
Chemistry World July 23, 2012 Melissae Fellet	RNA wrapper protects small molecules Step aside benzene rings, there's a new protecting group in town. Dutch researchers have used a strand of RNA to cover portions of a complex small molecule. They then chemically modified a portion of the molecule not covered by the RNA.
Chemistry World April 7, 2008 Simon Hadlington	Polyketide ring mystery solved US researchers have worked out how some microbes produce polyketides - a class of polycyclic compounds that have antibiotic and anti-cancer properties but are difficult to manufacture.
Chemistry World February 17, 2014 Helen Bache	Small molecules stop cervical cancer virus assembling Researchers in China have disrupted the life cycle of the leading cause of cervical cancer -- the human papilloma virus -- using a macrocyclic molecule called a pillarene.
Chemistry World October 16, 2006 Michael Gross	Brief Encounter Observing fleeting interactions between molecules in solution requires extremely sophisticated methods. NMR spectroscopists have now developed tools that let them watch the transient encounter between two proteins before a well-defined complex is formed.
Chemistry World May 12, 2011 Jon Cartwright	'Chemical soldering' heralds single molecule electronics Scientists in Japan and Switzerland have demonstrated how to wire up single molecules with conductive nanowires.
Chemistry World April 12, 2007 Simon Hadlington	Fatty Acid Factory Revealed X-ray crystallographers have achieved the Herculean task of elucidating the architecture of one of biochemistry's most impressive molecular machines, the multi-enzyme fatty acid synthase.
Chemistry World February 21, 2007 Tom Westgate	Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules.
Chemistry World March 22, 2012 Ross McLaren	Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule.
Chemistry World May 26, 2010 Phillip Broadwith	Pain target enzyme's working made crystal clear An enzyme that influences how we feel pain and is a potential target for treating anxiety has been crystallised and its structure solved by US scientists.
Chemistry World December 13, 2011 Jon Cartwright	Scientists unveil tiniest switch Researchers in Germany claim to have created the world's smallest molecular switch, relying on the movement of just a single proton.
Technology Research News April 7, 2004	Chip-camera combo tracks viruses Researchers from Purdue University have devised methods of labeling virus structural elements and DNA, of imaging virus particles as they flow through labs-on-a-chip, and of concentrating virus particles.
BusinessWeek November 24, 2003 John Carey	Barring The Door Against AIDS A new generation of drugs focuses on keeping the virus from entering cells.
Chemistry World November 6, 2009 Phillip Broadwith	Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before.