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Chemistry World February 27, 2006 Michael Gross |
A DNA Switch for RNA Folding Researchers have equipped a large RNA domain with a DNA switch, which they say can fold or unfold the RNA molecule at will. |
Chemistry World September 23, 2009 Simon Hadlington |
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. |
Chemistry World April 20, 2009 James Urquhart |
New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought. |
Chemistry World March 31, 2009 Jon Cartwright |
Blood clotting light work for new molecule The molecule, which works with the help of an enzyme, could one day be used in medicine to shut off blood supply to localized areas of the human body such as tumors. |
Chemistry World April 7, 2011 Laura Howes |
Long chains give new life to RNA world hypothesis The so-called RNA world hypothesis has gained fresh momentum with the synthesis of the longest lab grown RNA strands made using an enzyme that is itself made of RNA, an 'RNAzyme'. |
Chemistry World January 8, 2012 David Bradley |
The TNA world that came before the RNA one Once it was recognised that DNA is key to the molecular self-replication that underpins life, chemists have sought to understand the origins of this double-helical molecule in that primordial age. |
Chemistry World May 13, 2009 James Urquhart |
Insight into RNA origins UK researchers have offered new insight into the origins of RNA and possibly life itself. |
Chemistry World February 8, 2006 Jon Evans |
To Boldly go Where no Chemist Has Gone Before Studying the interactions between different molecular fragments is taking researchers to the uncharted regions of chemical space. |
Chemistry World November 28, 2006 Michael Gross |
Synthesis Success After 30 Years Chemists at Harvard have succeeded in synthesizing the antibiotic moenomycin A from scratch. They hope that by providing easier access to this molecule and its variants, they might aid the development of new antibiotics based on its structure. |
Chemistry World August 30, 2009 Phillip Broadwith |
C-H oxidation proves its worth US researchers are going against the grain of total synthesis and developing new approaches to complex molecules. |
Chemistry World October 19, 2007 Richard Van Noorden |
Building Tomorrow's Nanofactory UK scientists have been granted 2.5 million pounds to invent a nanomachine that can build materials molecule by molecule. Such a robot doesn't -- and may never -- exist, though it has been imagined for over half a century. |
Chemistry World February 12, 2014 Manisha Lalloo |
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. |
Chemistry World March 15, 2007 Henry Nicholls |
The Mother of All Enzymes Scientists have uncovered the three-dimensional structure of what might be biology's first enzyme. This sheds light on the chemistry at a key moment in the origin of life, they argue. |
Chemistry World April 19, 2012 Andy Extance |
Polymers perform non-DNA evolution Scientists have found that six polymer alternatives to DNA can pass on genetic information, and have evolved one type to specifically bind target molecules. |
Chemistry World June 9, 2008 Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Chemistry World November 2, 2015 |
Batzelladine B Of all the diverse substances that nature produces, the alkaloids -- small molecules containing basic nitrogen -- have had the greatest impact on human history and health. |
Technology Research News August 27, 2003 |
Light makes molecule shine Researchers from Kyushu University in Japan have constructed a fluorescent molecule that can be repeatedly switched on and off. If a way can be found to switch individual, closely-packed molecules on and off, fantastic amounts of information could be stored in very small spaces. |
Technology Research News January 12, 2005 |
RNA Tiles Form Nanopatterns Researchers have developed a method of coaxing artificial RNA molecules to self-assemble into specific shapes, much like a jigsaw puzzle automatically assembling. The structures could eventually be used as templates for nanochips, nanocircuits and nanocrystals |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World January 19, 2010 Simon Hadlington |
New 'click' reaction to modify proteins Chemists in the US have discovered a new way to attach small molecules to proteins and peptides under mild, aqueous reaction conditions. |
Chemistry World June 11, 2008 Simon Hadlington |
Houdini Molecule Escapes Energy Trap A team of international chemists has captured and caught on camera a small, elusive molecule that has previously never been seen. |
Chemistry World March 22, 2012 Ross McLaren |
Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule. |
Chemistry World October 11, 2009 Simon Hadlington |
Diode breakthrough in molecular electronics Researchers from the US and Russia have shown how it is possible to measure the diode properties of a single molecule and how the orientation of the molecule between two electrodes can be controlled. |
Chemistry World March 2012 |
Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug |
Chemistry World October 20, 2008 Hayley Birch |
RNA computers built in yeast US scientists have assembled ribonucleic acids into an adaptable logic system that can be programmed to sense and respond to molecules inside living yeast cells. |
Technology Research News November 5, 2003 |
Paired molecules store data Researchers from the University of California at Irvine have bonded a pair of molecules to form a molecule that has two states. The components are photochromic fulgimide and a dye molecule capable of florescence. |
Chemistry World February 2011 |
Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential |
Chemistry World October 10, 2010 Andy Extance |
DNA strides into organic synthesis US scientists have used a DNA walker to synthesise an organic molecule in a series of steps, without intervention, for the first time. |
Chemistry World April 2007 Derek Lowe |
Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort? |
Scientific American June 2005 JR Minkel |
RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right. |
Chemistry World February 1, 2008 Lewis Brindley |
Genetic Code Read Directly From RNA Scientists have directly read the genetic code from a single strand of RNA for the first time, using a combination of powerful microscopes and laser spectroscopy techniques. |
Chemistry World February 21, 2007 Tom Westgate |
Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules. |
Chemistry World January 9, 2009 James Urquhart |
Chemists edge closer to recreating early life A test tube based system of chemicals that exhibit life-like qualities such as indefinite self-replication, mutation, and survival of the fittest, has been created by US scientists. |
Chemistry World August 6, 2007 Tom Westgate |
Unique Antibiotic Beats Superbugs' Resistance The discovery of how a unique antibiotic kills its targets has uncovered a new way to tackle resistant superbugs. A team of chemists and structural biologists have studied how the natural antibiotic lactivicin interacts with a crucial bacterial protein. |
Chemistry World November 3, 2008 Simon Hadlington |
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? |
Reactive Reports Issue 63 David Bradley |
Chemists Go Round the Bend Chemists often think of molecular wires as "shape-persistent" rods with limited flexibility, but researchers have now shown that molecular wires can be bent into ring shapes. |
Technology Research News November 19, 2003 |
Molecular memory is electric Researchers from Osaka Kyoiku University in Japan have found a way to use a single molecule to store computer information. |
Chemistry World August 8, 2006 |
Single Molecule Makes Electronic Switch A single molecule, trapped between two electrodes, acts as a switch and has a `memory' of the type used in data storage, researchers have found. |
Chemistry World November 13, 2008 Hayley Birch |
Reactions Studied by Stop Motion Japanese and Israeli scientists have developed a technique that can track whole-molecule changes that occur during extremely rapid reactions. |
Technology Research News December 3, 2003 |
Molecule does two-step Duke University researchers have found a way to make a molecule react only when it has been hit by two photons of ultraviolet light, making the molecule a controllable switch. The molecule could eventually be used in optical storage devices and in biochips. |
Technology Research News March 12, 2003 |
RNA forms nanomotor Researchers from Purdue University have constructed a tiny motor from DNA and RNA molecules. The device, fueled by ATP, which powers our own movements, could eventually power nanomachines. |
Technology Research News August 13, 2003 |
Molecule makes ring rotor Researchers from the University of Edinburgh in Scotland have interlocked large, ring-shaped molecules to make a molecular rotor that moves in only one direction. The molecule could eventually be used as a nanoscale motor or winch. |
Chemistry World March 2, 2006 Michael Gross |
Chemists Crack Cocaine Detection Researchers, including two high school students and a Nobel laureate, have created a sensitive, easy to use device to detect cocaine and other small molecules. |
Chemistry World July 30, 2014 |
Psylloborine A It's a somewhat surprising assertion that almost a fifth of natural products are thought to include a dimerization step somewhere in their biosynthesis. |
The Motley Fool September 28, 2007 Brian Orelli |
RNAi Doesn't Kill Mice After All From Merck, to AstraZeneca, to Novartis, big pharma continues to pump hundreds of millions of dollars into unproven RNAi technology. Investors, take note. |
Chemistry World October 15, 2008 Simon Hadlington |
Long-life light illuminates cells The new dye, based on platinum, will carry on emitting light long after any interfering 'autofluorescence' from naturally occurring molecules in the cell has fizzled out. |
Scientific American March 2009 W. Wayt Gibbs |
Evolution in a Bottle: Synthetic Life Oozes Closer to Reality Self-replicating RNAs advance science another step toward artificial life |
Chemistry World February 2007 Dylan Stiles |
Bench Monkey There's a recurring problem in synthesis where functional groups in a molecule are prone to unwanted side reactions. |
Chemistry World May 29, 2013 Paul Docherty |
Pactamycin A member of a 'rival' field stating that a molecule is 'inaccessible by synthetic organic chemistry' is like a red rag to the proverbial bull. This challenge surrounds analogs of pactamycin, a complex cyclopentane-based target with an exceptionally potent biological profile. |
Chemistry World October 15, 2012 Simon Hadlington |
ExBox snares polycyclic aromatic hydrocarbons US chemists have designed a novel macrocyclic molecule that may be able to scavenge an important class of toxic hydrocarbons from the environment. |