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Chemistry World September 10, 2008 Simon Hadlington |
Failed anxiety drug could treat cancer Scientists believe they have solved the mystery of how a drug originally developed for treating anxiety can kill cancer cells. |
Chemistry World June 2008 Sarah Houlton |
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success |
Chemistry World November 6, 2009 Phillip Broadwith |
Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before. |
Chemistry World March 6, 2008 Simon Hadlington |
Synthetic Enzymes Designed by Computer Scientists in the US have designed and built an artificial enzyme from scratch. |
Chemistry World June 21, 2007 Simon Hadlington |
Boron is Key to Antifungal Agent Researchers have shown that the presence of a boron atom is key to an antifungal agent being developed to treat infections of fingernails and toenails. |
Chemistry World April 12, 2007 Simon Hadlington |
Fatty Acid Factory Revealed X-ray crystallographers have achieved the Herculean task of elucidating the architecture of one of biochemistry's most impressive molecular machines, the multi-enzyme fatty acid synthase. |
Chemistry World November 18, 2010 Hayley Birch |
'Hunger hormone' activating enzyme holds promise as obesity target Blocking a key gut enzyme involved in the hunger response can reduce weight gain in mice, say US and Taiwanese researchers. The approach could eventually lead to treatments for obesity in humans that would work by damping down hunger pangs. |
Chemistry World January 24, 2011 Andy Extance |
Dimer delivers pinpoint recognition US researchers have synthesised a supramolecular host system that provides novel selective recognition of two different guest molecule types without cross-over or interference. |
Chemistry World December 2008 |
Column: In the pipeline I've worked on two drug discovery efforts (one right after the other, as fate would have it) whose final compounds differed by essentially one methyl group from the starting points of each project. |
Chemistry World September 24, 2007 Simon Hadlington |
Viral Nanoreactor Captures Single Molecules Researchers in the Netherlands have created a biochemical nanoreactor by cracking open a virus, removing its contents then reassembling the virus's protein coat around a single molecule of enzyme. |
Chemistry World October 14, 2008 Simon Hadlington |
Enzymes hit with double punch US chemists have made a small molecule that simultaneously blocks two key enzymes involved in the growth of cancer cells. |
Chemistry World April 14, 2006 Simon Hadlington |
Deciphering Hydrogen Tunnelling in Enzymes Researchers have thrown important new light on the phenomenon of hydrogen tunnelling in biological catalysts. The finding is likely to spark a debate among biochemists about the fundamental nature of enzymes. |
Chemistry World September 9, 2007 Simon Hadlington |
Sugaring the Pill Researchers in the US have made a key advance in efforts to bolt sugar molecules onto natural products in the search for new drugs. |
BusinessWeek January 17, 2005 Catherine Arnst |
No Pain, Some Gain The 50 million Americans suffering from chronic pain got a little bit of good news in December. The Food & Drug Administration greenlighted two new medications that attack pain in completely novel ways. |
Chemistry World January 6, 2010 Phillip Broadwith |
Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain. |
Chemistry World October 11, 2009 Simon Hadlington |
Diode breakthrough in molecular electronics Researchers from the US and Russia have shown how it is possible to measure the diode properties of a single molecule and how the orientation of the molecule between two electrodes can be controlled. |
The Motley Fool March 4, 2010 Brian Orelli |
A Painless Drug Deal Bristol-Myers licenses pain drug from Allergan. |
Chemistry World August 13, 2009 Simon Hadlington |
Forcing enzyme activity New research has shown that physically stretching an enzyme can trigger its activity - even when the active site is not hidden in a 'cryptic' position. Mechanical force may play a more important role in biological molecular systems than previously realized. |
Chemistry World March 17, 2009 Phillip Broadwith |
Electronic 'nose' could shed light on sense of smell Korean researchers have combined human smell receptors with nanotechnology to create a new kind of 'bio-electronic nose' |
Chemistry World March 20, 2007 Lionel Milgrom |
Chemical Model Unlocks Key Enzyme's Secrets The precise workings of cytochrome c oxidase (CcO), an enzyme that is crucial for all aerobic life, have been unveiled. |
Chemistry World January 17, 2010 Simon Hadlington |
Sugars synthesised with help of promiscuous enzyme European researchers have discovered a new way to make synthetically elusive sugar molecules that could lead to novel vaccine candidates and other medically important compounds. |
Chemistry World February 2011 |
Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential |
Chemistry World March 31, 2009 Jon Cartwright |
Blood clotting light work for new molecule The molecule, which works with the help of an enzyme, could one day be used in medicine to shut off blood supply to localized areas of the human body such as tumors. |
Chemistry World May 2, 2007 Michael Gross |
Protein Printboard Chemists in the Netherlands have created nanoscale structures that can immobilize proteins with exquisite control over specificity, strength and orientation. |
Chemistry World June 17, 2010 Andrew Turley |
Biocatalyst improves diabetes drug production Researchers have developed an enzyme that can produce a difficult to form chiral amine in a best-selling diabetes therapy. |
Chemistry World August 29, 2007 Ananyo Bhattacharya |
'Lost' Folate Enzyme Found After 30 Years US researchers have revealed the identity of an enzyme used by bacteria to make the essential B vitamin folate, 30 years after it was first isolated. |
Chemistry World November 26, 2010 Rebecca Brodie |
Printing on bioactive paper An enzyme printing process that prints the product of an enzyme-catalysed reaction, but not the enzyme molecule itself, has been designed by scientists in Australia to produce bioactive paper. |
Chemistry World May 18, 2011 James Urquhart |
Throwing light on molecular logic gates The multifunctional molecule, which can be reconfigured by light, could be used in data storage devices and biomedicine, including nanoparticle tracking and drug delivery. |