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Bio-IT World
Dec 2006/Jan 2007
John Russell
Setting the Systems Bio Syllabus An interview with David de Graaf about Pfizer's growing comfort with systems biology. mark for My Articles similar articles
Bio-IT World
February 2006
John Russell
Marvelous Models of Biological Systems Here are highlights from a roundtable discussion with researchers representing academia and pharmaceuticals, as well as executives from modeling technology providers on whether or not Pharma is ready to bet on computational modeling of biological systems. mark for My Articles similar articles
Bio-IT World
June 17, 2004
John Russell
Systems Biology - Now Leaving on Track 1 Entelos, a leader in predictive biosimulation, partners with pharmaceutical and biotech organizations worldwide to develop effective new treatments for disease. Michael French, chief business officer at Entelos, explains what powers the systems biology engine. mark for My Articles similar articles
Bio-IT World
March 8, 2005
John Russell
Entelos' Lofty Aspirations This is an interesting period for systems biology's wing of predictive biology companies. The label's luster is fading, but buoyed by pharma's growing interest, they are trying to figure out how to grow. mark for My Articles similar articles
Bio-IT World
September 2005
John Russell
Labor Pains and Gains Labor Day is the starting gun for the bio-science industry's race through the next year. Here are some up-and-coming items to watch: Transparency... Systems Biology... Crawford and McClellan... mark for My Articles similar articles
Bio-IT World
September 2006
John Russell
Informatics Cornucopia Predictive Informatics, the hopeful title of a session at last month's Drug Discovery Technology & Development World Congress, remains an enticing but mostly elusive goal. Asked what systems biology would look in five years and what will constitute success, panelists offered the following. mark for My Articles similar articles
Bio-IT World
November 12, 2002
Michael Goldman
A Virtual Pharmacopeia Computational modeling of disease pathways, organs --- even patients --- could transform drug discovery. Does salvation exist in silico? mark for My Articles similar articles
Bio-IT World
May 19, 2004
John Russell
Seeing the Forest and the Trees A tiny clearing in the fog of systems biology. mark for My Articles similar articles
Bio-IT World
October 2006
John Russell
GNS Charts "Unknown" Biology Gene Network Sciences' CEO and colleagues now think they have the right tool to mine the treasure trove of unknown biology hidden in the wealth of accumulating omic data. mark for My Articles similar articles
Bio-IT World
Dec 2006/Jan 2007
John Russell
Novartis' Answer to Harry Potter Imagine a magic wand able to instantly materialize novel, safe, and effective drugs. No such device exists, of course, but Novartis has a distant cousin of sorts: the UltraLink is an immensely powerful text-mining tool and knowledge management platform. mark for My Articles similar articles
Bio-IT World
October 14, 2004
Deciphering Genstruct If you divide the systems biology world into two broad camps, wet-lab-focused data generators and in silico model makers, Genstruct is a modeler with a twist. mark for My Articles similar articles
Bio-IT World
February 10, 2003
Salvatore Salamone
Made in Manhattan A talk with the new head of the Computational Biology Center at Memorial Sloan-Kettering. mark for My Articles similar articles
Bio-IT World
May 9, 2003
Michael Greeley
Mechanistic Models Investors are backing predictive modeling software that could speed drug development. mark for My Articles similar articles
Bio-IT World
December 15, 2003
Zachary Zimmerman
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. mark for My Articles similar articles
Bio-IT World
February 2006
John Russell
Preventable Vioxx Problems? Pathway analysis tools might have identified Vioxx's problematic off-target activity much earlier. Wondering which modeling approach to use for your project? mark for My Articles similar articles
Bio-IT World
March 2007
John Russell
In Search of Spring Tired of winter? Here are some signs of spring for systems biology acceptance and a preview of Cambridge Healthtech's June conference, Applying Systems Biology, to whet your appetite for summer: 1. FDA Survey... etc. mark for My Articles similar articles
Bio-IT World
November 2006
John Russell
Pathway Pioneers Innovative uses for pathway tools and exciting results from early users are sprouting like mushrooms after a spring rain -- albeit following a few harsh winters. And the usually risk-averse pharmaceutical industry has led in adopting pathway tools. mark for My Articles similar articles
Bio-IT World
June 12, 2002
John Dodge
All Systems Go at ISB The Seattle-based Institute for Systems Biology (ISB), takes a holistic view of genomic and proteomic research. The author spoke with its president, noted biologist Leroy Hood, recently to find out how far ISB has come in its two years of life. mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Sarah C.P. Williams.
Carolyn Bertozzi: Changed Expectations Chemists trained in biology were once a rarity -- now they're becoming the norm. mark for My Articles similar articles
Bio-IT World
January 21, 2005
Defining 'Integrative Genomics' Five experts from academia and industry discuss the burgeoning field of integrative genomics. mark for My Articles similar articles
Bio-IT World
December 15, 2003
Mark D. Uehling
Model Patient Despite the FDA's new support for computational modeling, the pharmaceutical industry remains cautious about simulating clinical trials. mark for My Articles similar articles
Bio-IT World
Jul/Aug 2006
John Russell
MathWorks Launches a 'Systems Biology' Tool The maker of the popular MATLAB programming environment recently launched a modeling product, SimBiology, aimed at systems biology and synthetic biology markets. mark for My Articles similar articles
Pharmaceutical Executive
October 1, 2011
Atsushi Nagahisa
Creating Customer Value: It's No Distant Dream The author speaks about how the pharmaceutical industry can fix today's greatest global policy challenge: leveraging hard science to address an enormous -- and growing -- burden of unmet medical need. mark for My Articles similar articles
Bio-IT World
August 18, 2004
Mark D. Uehling
I, Virtual Patient Along with a software company specializing in modeling diseases on the computer, Roche Diagnostics is working on creating a new biomarker for diabetes that could be reduced to a simple blood test. mark for My Articles similar articles
Bio-IT World
March 2006
John Russell
It's All About the Drugs A conversation with biopharma Organon's executive VP for global research and development highlights how, regardless of the company's enthusiasm for new technology, it is first and foremost interested in pharmacology and medicinal chemistry -- drugs. mark for My Articles similar articles
Bio-IT World
August 2005
John Russell
Pfizer's Model of Success Pfizer Global Research & Development began using sophisticated modeling technology and collaboration software to speed its race to a go-no-go decision on a cholesterol-lowering drug project. Killing the project sooner saved up to $2.8 million in costs and six months in delay. mark for My Articles similar articles
Chemistry World
September 13, 2012
Andy Merritt
Chemical biology comes of age Historically strongest in the US, chemical biology has become increasingly important worldwide, but for many years researchers at the chemistry -- biology interface have struggled to establish their discipline mark for My Articles similar articles
Bio-IT World
October 2005
John Russell
Compugen Transforms Its Business Many informatics pioneers discovered the hard way that selling software licenses and fee-for-services can't always pay the bills. Tel Aviv-based Compugen, is working to reinvent itself as a drug discovery and development player. mark for My Articles similar articles
Bio-IT World
July 14, 2004
Malorye A. Branca
The Pathways Promise By using the right tools, even a modest genomic data set can generate a good view into a particular biological pathway. Now, a range of new technologies is arising from academia as well as the commercial sector to meet this need. mark for My Articles similar articles
Bio-IT World
September 2006
Nat Goodman
Getting a Handle on Systems Biology Systems biology is squarely an experimental field that eats, drinks, and breathes data. To do systems biology, you need an experimental system that is amenable to large-scale experimentation. mark for My Articles similar articles
Bio-IT World
January 12, 2004
Julia Boguslavsky
New Year Tools for the 'New' Biology Instrumentation outlook for systems biology. mark for My Articles similar articles
Bio-IT World
Dec 2006/Jan 2007
Resolute in the New Year Industry leaders in areas from pharmacogenetics to cheminformatics found 2006 to be a year of important steps forward, but looked with even more anticipation to 2007: Allen D. Roses, SVP, Pharmacogenetics GlaxoSmithKline... etc. mark for My Articles similar articles
Bio-IT World
Dec 2006/Jan 2007
Giacomo Bastianelli
The Future of Predictive Biology Predictive biology, data and the integration of disparate research disciplines are key ingredients for the future of drug discovery research and healthcare. mark for My Articles similar articles
Bio-IT World
July 11, 2002
Mike Fitzgerald
Funding the Future Investor G. Steven Burrill, CEO of Burrill & Company, helps biotech companies fulfill their potential. He talked recently about his view of the bio-IT field. mark for My Articles similar articles
Chemistry World
May 1, 2014
Ned Stafford
Synthetic biology vision for Europe unveiled A new 'strategic vision' for synthetic biology has laid out the steps Europe needs to take in the next five to 10 year to nurture the field, with chemistry a key part of its strategy. mark for My Articles similar articles
Bio-IT World
March 17, 2004
Systems Biology: Top-Down or Bottom-Up? Systems biology involves the representation and analysis of an intact biological system. Like many of the technological developments over the past 20 years, such as genomics, proteomics, combinatorial chemistry, and bioinformatics, pharma and medical communities hold high hopes that systems biology will help move molecular research closer to the practice of medicine. mark for My Articles similar articles
Bio-IT World
April 2007
John Russell
Toward a Cancer Interactome Researchers at the Center for Cancer Systems Biology are working toward identifying the high level wiring diagram for cancer. In this instance, that means an accurate map of all cancer-associated protein-protein interactions. mark for My Articles similar articles
Bio-IT World
March 17, 2004
Pharma's Genomic Harvest How Pfizer plans to meet its goal of 20 new drug applications by 2006. mark for My Articles similar articles
Chemistry World
January 2012
Cultivating collaboration A new network aims to bring the power of interdisciplinary innovation to bear on global food issues. mark for My Articles similar articles
Knowledge@Wharton A New Approach to Valuing Biotech Stocks Enormous swings in biotechnology stock prices during the last few weeks show how difficult it is for investors to value biotech companies. It's important to understand the invisible potential locked up in the organizational structure of biotechnology companies... mark for My Articles similar articles
Bio-IT World
May 2006
Kevin Davies
Trailblazers Test Public Markets Three companies in postgenomic fields are going public. Infinity Pharmaceuticals, Perlegen Sciences, and Entelos announced they would be entering the public markets by means of merger, IPO, and institutional offering. mark for My Articles similar articles
Bio-IT World
January 21, 2005
Salvatore Salamone
A Prescription for Information-Based Medicine TurboWorx president and CEO Jeff Augen not only combines computational and biology expertise, but also has a clear vision of how to advance life science discovery. mark for My Articles similar articles
Chemistry World Fishing for Chemical Answers to Biological Questions James K. Chen talks about chemical biology, his love for the outdoors and fly fishing. mark for My Articles similar articles
Bio-IT World
January 13, 2003
John Dodge
Talent Fuels Drug Pipeline in Swiss Time The functional genomics group has emerged as a critical link in the drug discovery chain at Novartis Pharmaceuticals Corp. While it employs a multidisciplinary approach to drug discovery, the four-year-old group's goals could not be simpler: Find novel drug targets. mark for My Articles similar articles
Bio-IT World
January 21, 2005
Best Practices 2005: Strut Your Stuff Organizations are invited to strut their stuff for Bio*IT World's annual awards program. mark for My Articles similar articles
Bio-IT World
July 2005
John Russell
Harvard Tackles Systems Biology Towards the end of this summer, researchers at the Virtual Cell Program expect to unleash b -- pronounced "little b" -- a new open-source computer language they hope will energize the biological modeling community as nothing has before. mark for My Articles similar articles
Bio-IT World
August 15, 2005
Kevin Davies
Hood Hails 'Century of Biology' Leroy Hood won the 2005 Bio-IT World President's Award for his work on the synthesis of DNA and protein, and on the genome project. mark for My Articles similar articles
Bio-IT World
Dec 2005/Jan 2006
John Russell
GeneGo's Pathway to Profits Steady growth in literature citations plus several major pharmaceutical deals and now a recent FDA commitment suggest pathway technology is gaining sufficient credibility and the furthest along commercially of all the systems biology niches. mark for My Articles similar articles
Bio-IT World
August 18, 2004
Project Summaries Drug Discovery and Development: Ace BioSciences... Compugen... Entelos/Organon... Iconix Pharmaceuticals... Johnson & Johnson Pharmaceutical Research & Development... Laboratoire Kastler Brossel ... etc. mark for My Articles similar articles
Bio-IT World
May 2006
John Russell
Kurzweil: Life Is the Fast Lane Inventor and futurist Ray Kurzweil's opening keynote at the Bio-IT World Life Sciences Conference + Expo painted an optimistic vision of a world governed by growing information technologies that will transform what it means to be human. mark for My Articles similar articles