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CIO
October 15, 2001
Stephanie Overby
Drug Companies on speed The marriage of IT and medical research may be just what traditional pharmaceutical companies need to survive in an increasingly competitive field. Learn how IT is bringing the pharmaceutical industry into the information age... mark for My Articles similar articles
Bio-IT World
November 12, 2002
James Golden
The Business of Bioinformatics The industry has reached an interesting crossroads. As an academic branch of learning, bioinformatics remains mostly what it always was, a cross-disciplinary endeavor between computer science and molecular biology. But bioinformatics as a money-making proposition has different criteria for success. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Mark D. Uehling
Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials. mark for My Articles similar articles
Bio-IT World
July 11, 2002
Malorye Branca
Deep Sequence Diving Like sailors of old, genomic data miners dream of discovering riches and fame. Given the recent improvements in analytics -- and a little more time -- they just might succeed. mark for My Articles similar articles
Bio-IT World
November 12, 2002
Michael Goldman
A Virtual Pharmacopeia Computational modeling of disease pathways, organs --- even patients --- could transform drug discovery. Does salvation exist in silico? mark for My Articles similar articles
Bio-IT World
December 15, 2003
Zachary Zimmerman
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. mark for My Articles similar articles
Bio-IT World
September 2006
Mike May
Working Out the Flow Better management of workflow issues in biotech and pharma could change fundamental aspects of these sciences in the near future. mark for My Articles similar articles
Bio-IT World
November 2006
John Russell
Pathway Pioneers Innovative uses for pathway tools and exciting results from early users are sprouting like mushrooms after a spring rain -- albeit following a few harsh winters. And the usually risk-averse pharmaceutical industry has led in adopting pathway tools. mark for My Articles similar articles
Industrial Physicist
Jennifer Ouellette
Bioinformatics moves into the mainstream An explosion of data is being tamed with new systems mark for My Articles similar articles
Bio-IT World
April 15, 2003
Malorye Branca
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? mark for My Articles similar articles
Bio-IT World
February 10, 2003
Malorye Branca
Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic. mark for My Articles similar articles
Bio-IT World
November 2006
Kevin Davies
Jubilant Curries Favor with BioPharma The explosion of drug discovery and development operations in India is epitomized by the success of several companies. Quietly building on a decade of experience in computational and bio-IT fields, JBL is rapidly pushing into a suite of drug discovery and development activities. mark for My Articles similar articles
Bio-IT World
January 13, 2003
John Dodge
Talent Fuels Drug Pipeline in Swiss Time The functional genomics group has emerged as a critical link in the drug discovery chain at Novartis Pharmaceuticals Corp. While it employs a multidisciplinary approach to drug discovery, the four-year-old group's goals could not be simpler: Find novel drug targets. mark for My Articles similar articles
Bio-IT World
May 19, 2004
John Russell
Informatics Black Boxes ... Not! Vertex's chief technical officer, discusses informatics' bad reputation, buying vs. building, open-source tools, and ROI on IT. mark for My Articles similar articles
Bio-IT World
Dec 2006/Jan 2007
Kevin Davies
The NextBio Thing in Bioinformatics NextBio, which this fall officially introduced its platform after a year of beta testing by a handful of select organizations, aims to provide high-throughput information to researchers without them having to learn anything. mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Sarah C. P. Williams
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. mark for My Articles similar articles
Bio-IT World
April 2007
Vicki Glaser
Software Solutions for Medicinal Chemistry Driven by advances in chemical synthesis, instrumentation, and high-throughput and high-content screening technology, medicinal chemistry's transition from an art to a science is benefiting from a wealth of new software products, spanning both bio- and cheminformatics. mark for My Articles similar articles
Bio-IT World
December 10, 2002
Hillel Alpert
Bio-IT Shines Bright in Israel Companies such as Quark and Pharmos are still flourishing as other industries decline in this country torn by conflict. mark for My Articles similar articles
Bio-IT World
September 2006
John A. Wass
Integrating Knowledge The results of new mathematical routines have the potential to save pharmaceuticals millions of dollars in drug development. And yet the flow of successful drugs is dwindling. The problem goes beyond bureaucracy and lies in the complexity of the problem. mark for My Articles similar articles
Bio-IT World
February 10, 2003
Salvatore Salamone
Made in Manhattan A talk with the new head of the Computational Biology Center at Memorial Sloan-Kettering. mark for My Articles similar articles
Bio-IT World
October 9, 2002
Malorye Branca
The Path to Personalized Medicine The tactics have changed, sometimes dramatically, but hints of the promise of pharmacogenomics are finally starting to trickle in from studies of asthma, cancer, and drug response. mark for My Articles similar articles
Chemistry World Fishing for Chemical Answers to Biological Questions James K. Chen talks about chemical biology, his love for the outdoors and fly fishing. mark for My Articles similar articles
Bio-IT World
July 14, 2004
Malorye A. Branca
The Pathways Promise By using the right tools, even a modest genomic data set can generate a good view into a particular biological pathway. Now, a range of new technologies is arising from academia as well as the commercial sector to meet this need. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Donna Mendrick
Microarrays That Make Drugs Safe Using DNA chips to discover potential toxicity in new drug compounds -- a key application of toxicogenomics -- can predict adverse effects before they occur, enabling safer clinical trials. mark for My Articles similar articles
Bio-IT World
September 2006
Kevin Davies
Pfizer's Global Survey of Pharmacological Space The pharma blends knowledge, computational chemistry and research informatics to build a unified database. Gathering all the data in one place offered greater control for indexing and data retrieval and management, enabling Pfizer scientists to perform global mapping. mark for My Articles similar articles
Bio-IT World
March 10, 2003
Mark D. Uehling
Technology Overload Inundated with new IT tools and mountains of data, the pharmaceutical industry struggles to pull it all together. mark for My Articles similar articles
Bio-IT World
June 17, 2004
John Russell
Systems Biology - Now Leaving on Track 1 Entelos, a leader in predictive biosimulation, partners with pharmaceutical and biotech organizations worldwide to develop effective new treatments for disease. Michael French, chief business officer at Entelos, explains what powers the systems biology engine. mark for My Articles similar articles
Bio-IT World
August 13, 2002
Malorye Branca
The Proteomics Odyssey Efforts to map the constellation of protein interactions in humans gather momentum as companies vie to provide tools to capitalize on the potential of proteomics. But can proteomics prevail where some feel genomics has failed? mark for My Articles similar articles
Bio-IT World
Dec 2006/Jan 2007
John Russell
Novartis' Answer to Harry Potter Imagine a magic wand able to instantly materialize novel, safe, and effective drugs. No such device exists, of course, but Novartis has a distant cousin of sorts: the UltraLink is an immensely powerful text-mining tool and knowledge management platform. mark for My Articles similar articles
Bio-IT World
July 15, 2003
Millennium's PARIS Illuminates Pathways To address high-throughput-data challenges, Millennium Pharmaceuticals built the PAthway Resource and Information System, or PARIS -- a unique platform for combining knowledge from heterogeneous data sources in the construction of a pathway knowledgebase. mark for My Articles similar articles
Bio-IT World
May 9, 2003
Vivien Marx
The Sharper Image See it, capture it, mine it, find it. The budding field of image informatics is empowering biomedical research. mark for My Articles similar articles
Industrial Physicist
Apr/May 2003
Jennifer Oullette
Switching from physics to biology Physicists in transition help shape biological theory. mark for My Articles similar articles
Bio-IT World
November 2005
Bridges and Boundaries in Drug Discovery Research Good communication, blurring cultural boundaries, and strong project governance may be as, if not more, important as sweeping technology solutions when it comes to converging discovery and IT and expediting drug development. mark for My Articles similar articles
Fast Company
January 2002
George Anders
Roche's New Scientific Method How does a giant pharmaceutical company reckon with genomics technology? By making a fresh start in how it recruits its scientists, manages projects, and uses computers. Here's how the Roche Group is reinventing how it invents... mark for My Articles similar articles
Bio-IT World
November 2006
Robert M. Frederickson
Managing Data on the Go GeneGo has created a suite of software and database products that aim to facilitate analysis of the biology behind different types of high-throughput experimentation and understand the effects of small molecule drug compounds in human tissues. mark for My Articles similar articles
Bio-IT World
October 14, 2004
Zachary Zimmerman
Follow the Pathway to Increased ROI Although this software has been commercially available for only a year, Ingenuity claims nine of the top 10 pharmaceutical companies as customers, including Pfizer, Wyeth, GlaxoSmithKline, and Aventis. mark for My Articles similar articles
Pharmaceutical Executive
February 1, 2006
Ron Feemster
Gene Logic: Rescue Squad One or two late-stage clinical failures can land promising drug candidates on the shelf. Forever? Maybe not. Gene Logic tests Big Pharma's dead drugs for hundreds of different targets. mark for My Articles similar articles
Bio-IT World
March 2006
Bio-IT World Bio-IT 50 The 50 companies profiled here have driven and continue to drive the future of biomedical research and drug discovery: Accelrys... Affymetrix.. Apple... Becton Dickinson... BlueArc... 454 Life Sciences... etc. mark for My Articles similar articles
Bio-IT World
February 2006
John Russell
Marvelous Models of Biological Systems Here are highlights from a roundtable discussion with researchers representing academia and pharmaceuticals, as well as executives from modeling technology providers on whether or not Pharma is ready to bet on computational modeling of biological systems. mark for My Articles similar articles
Bio-IT World
July 2005
Kevin Davies
Medicine Gets Personal Touch More genomics-based drugs are moving into development with others, such as new cancer drugs showcasing on the clinical pharmacogenics scene as outlined in the Advances in Genomic Medicine program of a recent world conference. mark for My Articles similar articles
Bio-IT World
June 12, 2002
Beth Schachter
Informatics Moves to the Head of the Class The race is on to increase the quantity and quality of bio-IT training programs as government and academia bet the need will be great. Will the job market back up that bet? mark for My Articles similar articles
Bio-IT World
May 7, 2002
Malorye Branca
In Silico Survivors Facing desperate times, bioinformatics companies revamp, refocus, or perish. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Mark D. Uehling
Digging Into Digital Quarries Industrial-strength software is helping discover unexpected connections in the scientific literature. mark for My Articles similar articles
Bio-IT World
August 13, 2003
Malorye Branca
Targeting Tumors Next-generation cancer drugs will take aim with unprecedented certainty, but making them requires a new discovery and development paradigm. mark for My Articles similar articles
Wired
August 2004
Oliver Morton
A Machine With a Mind of Its Own Ross King wanted a research assistant who would work 24/7 without sleep or food. So he built one. King's robot can look at the results of a biology experiment, draw a conclusion about what the results might mean, and then set off to test that conclusion. mark for My Articles similar articles
Bio-IT World
February 2007
Mike May
No Limits: The New Look of LIMS As vendors and scientists work towards standardized data formats and improving the tracking of research and results worldwide, laboratory information management systems can pull increasingly more complex sources of information into managing knowledge. mark for My Articles similar articles
Bio-IT World
July 14, 2004
Davies & Russell
The Sweet Hereafter Novartis' stunning new research home in a former candy factory is but one ingredient in a bold new recipe for success that embraces leadership, culture, science, and technology. mark for My Articles similar articles
Bio-IT World
September 2006
John Russell
Informatics Cornucopia Predictive Informatics, the hopeful title of a session at last month's Drug Discovery Technology & Development World Congress, remains an enticing but mostly elusive goal. Asked what systems biology would look in five years and what will constitute success, panelists offered the following. mark for My Articles similar articles
Bio-IT World
September 2005
Salvatore Salamone
Fujitsu Modeling Improves In Silico ADME/Tox Predictions The company's BioSciences Group is now offering its expertise in this area as a form of consulting service to help companies develop enhanced in silico ADME/Tox predictive results. mark for My Articles similar articles
Bio-IT World
Jul/Aug 2006
Deb Janssen
Managing the Microarray Data Mountain Genomic studies often involve thousands of samples and require hundreds of thousands of assays per sample. Microarray manufacturers are scurrying to satisfy researcher demands for increased array density, sample number, and content flexibility. mark for My Articles similar articles