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Bio-IT World April 15, 2003 Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
Wired August 2003 Jennifer Kahn |
The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine. |
Bio-IT World December 15, 2003 Zachary Zimmerman |
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. |
Bio-IT World May 2006 Kevin Davies |
Interpreting Genes and Genomes From microarrays to sequencing technology, molecular diagnostics to the interactome, this year's Bio-IT World Conference showcased exciting advances in genome technology applications, in which software analysis and data management play critical roles. |
HHMI Bulletin Nov 2010 |
Fusion genes that drive solid tumors are a new target for cancer therapies The success of Gleevec and related drugs has inspired researchers to step up their hunt for the molecular defects underlying other cancers. |
Bio-IT World June 2006 Kevin Davies |
The Data Deluge: Deal or No Deal? Far from decrying the data glut, researchers should embrace the complexity of genomic and other sources of data, particularly for its predictive properties in the field of personalized medicine. |
Bio-IT World February 10, 2003 Salvatore Salamone |
Made in Manhattan A talk with the new head of the Computational Biology Center at Memorial Sloan-Kettering. |
Bio-IT World September 11, 2003 John Russell |
Not Some Mickey Mouse Operation A week at The Jackson Laboratory reveals much of the nature of mice and men. |
Bio-IT World April 2006 Kevin Davies |
Harvard Opens Breast Cancer Protein Library In a landmark for functional proteomics, researchers at Harvard Medical School have unveiled a publicly available library of proteins that are active in breast cancer tissue. The resource could help speed drug discovery efforts against the disease. |
Bio-IT World June 12, 2002 John Dodge |
All Systems Go at ISB The Seattle-based Institute for Systems Biology (ISB), takes a holistic view of genomic and proteomic research. The author spoke with its president, noted biologist Leroy Hood, recently to find out how far ISB has come in its two years of life. |
Chemistry World July 2010 Hayley Birch |
Special Report: Health breakthroughs of the decade New discoveries have been made with cancer vaccines, genomics, statin drugs, allosteric modulators, and RNA interference during the last decade. |
Bio-IT World September 2006 Nat Goodman |
Getting a Handle on Systems Biology Systems biology is squarely an experimental field that eats, drinks, and breathes data. To do systems biology, you need an experimental system that is amenable to large-scale experimentation. |
Pharmaceutical Executive July 1, 2011 Dickmeyer & Rosenbeck |
From Rut to Racetrack Can the pharmaceutical industry deliver on its objective to make cancer a curable, chronic condition? |
Wired August 2004 Oliver Morton |
A Machine With a Mind of Its Own Ross King wanted a research assistant who would work 24/7 without sleep or food. So he built one. King's robot can look at the results of a biology experiment, draw a conclusion about what the results might mean, and then set off to test that conclusion. |
Bio-IT World August 13, 2002 Kevin Davies |
Curtailing the Cancerous Cell The highly touted drug Gleevec unleashed new hope in the battle against cancer. Now a group of new drugs, working on the same principle, are showing even greater promise in treating leukemia. |
AskMen.com Jacob Franek |
New Cancer Therapies As cancer research explodes, the availability of new and innovative interventions is expanding almost daily. |
Bio-IT World October 2006 Kevin Davies |
Cracking the Cancer Genome Regardless of which technologies win out, or which centers win the lucrative sequencing contracts, the Cancer Genome Atlas has a sublime medical and scientific importance, underscored by the latest findings from Hopkins. |
Industrial Physicist Apr/May 2003 Jennifer Oullette |
Switching from physics to biology Physicists in transition help shape biological theory. |
BusinessWeek May 12, 2011 Robert Langreth |
Big Pharma Bets on a Novel Cancer Cure Research in epigenetics is booming. The payoff could be in the billions. |
HHMI Bulletin May 2010 Robert Tjian |
Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens. |
HHMI Bulletin Nov 2011 Robert Tjian |
President's Letter: Intellectual Ferment There are exciting connections between chemistry and biology from both "sides" of the disciplinary divide. |
Bio-IT World August 13, 2003 Malorye Branca |
Targeting Tumors Next-generation cancer drugs will take aim with unprecedented certainty, but making them requires a new discovery and development paradigm. |
Bio-IT World March 17, 2004 |
Systems Biology: Top-Down or Bottom-Up? Systems biology involves the representation and analysis of an intact biological system. Like many of the technological developments over the past 20 years, such as genomics, proteomics, combinatorial chemistry, and bioinformatics, pharma and medical communities hold high hopes that systems biology will help move molecular research closer to the practice of medicine. |
BusinessWeek August 26, 2010 Tom Randall |
Cocktails Are Next For Cancer-Drug Makers Taking a cue from the cocktails of drugs that have made AIDS survivable, drugmakers are pursuing combination therapies against cancer. |
Chemistry World September 13, 2012 Andy Merritt |
Chemical biology comes of age Historically strongest in the US, chemical biology has become increasingly important worldwide, but for many years researchers at the chemistry -- biology interface have struggled to establish their discipline |
Scientific American March 2009 Elaine Schattner |
A Chip against Cancer: Microfluidics Scrutinizes T Cells With just a blood sample, a device could determine whether cancer is about to spread or monitor the progress of treatment |
Chemistry World |
Fishing for Chemical Answers to Biological Questions James K. Chen talks about chemical biology, his love for the outdoors and fly fishing. |
Scientific American May 2009 Christine Soares |
Cancer Clues from Embryonic Development Rethinking cancer by seeing tumors as a cellular pregnancy. |
American Family Physician October 1, 2000 |
Genetic Testing for Breast Cancer Risk: What Does It Mean to Me? What causes breast cancer?... What genes can cause breast cancer to be inherited?... What clues in my family history might show I've inherited a risk of breast cancer?... Does everyone who has family members with breast cancer have these mutated genes?... What should I do?... |
HHMI Bulletin Nov 2011 Sarah C.P. Williams. |
Carolyn Bertozzi: Changed Expectations Chemists trained in biology were once a rarity -- now they're becoming the norm. |
BusinessWeek June 13, 2005 Catherine Arnst |
Biotech, Finally The past 30 years of biological discoveries, insights into the human genome, and exotic chemical manipulation have unleashed a wave of biological drugs, many of them reengineered human proteins. |
Chemistry World July 6, 2012 |
Protein power Tom Muir, professor of chemistry and molecular biology, Princeton University, US, is an expert in protein engineering and its application to studying cellular signalling networks. |
The Motley Fool October 26, 2010 Ralph Casale |
Where We Are in the War on Cancer A summary of the roundtable discussions at Xconomy's recent event, "Boston's War on Cancer." |
Bio-IT World September 2006 John Russell |
Informatics Cornucopia Predictive Informatics, the hopeful title of a session at last month's Drug Discovery Technology & Development World Congress, remains an enticing but mostly elusive goal. Asked what systems biology would look in five years and what will constitute success, panelists offered the following. |
Pharmaceutical Executive February 1, 2013 William Looney |
In Cancer, Process Drives Progress Today's most important public health story is the advance in our understanding of the biology of cancer. |
Chemistry World January 21, 2011 Jennifer Newton |
Early lung cancer diagnosis Patients with lung cancer have elevated levels of a specific protein in their blood that could be used as a biomarker for the disease, say scientists from South Korea. |
Chemistry World January 2012 |
Cultivating collaboration A new network aims to bring the power of interdisciplinary innovation to bear on global food issues. |
Chemistry World May 28, 2008 Mark Peplow |
Cancer research gets collaborative funding boost In an effort to crack some of the biggest problems in cancer drug discovery, Cancer Research UK has launched a unique funding program that promises to help bridge the gap between fundamental research and big pharma pipelines. |
Scientific American January 2009 Charles Q. Choi |
Do White Blood Cells Make Cancer Deadly? The ability to spread underlies the killing power of cancer. The process occurs, John Pawelek thinks, when tumor cells fuse with white blood cells -- an idea that, if right, could yield new therapies |
InternetNews June 17, 2010 Andy Patrizio |
IBM and Idle PCs Help Find Anti-Cancer Drugs Distributed computing can break up a massive task into manageable chunks in certain situations. Is it right for your company? |
Wired Thomas Goetz |
Why Early Detection Is the Best Way to Beat Cancer By getting regular blood tests, doctors may be able to diagnose cancer early, giving the patient a 90 percent chance of survival. |
HHMI Bulletin Fall 2012 R. John Davenport |
Hanchuan Peng: SmartScopes Even when he launched his career as an engineer and computer scientist, Hanchuan Peng was drawn to the beauty of biology. He is a leader in developing sophisticated ways to make sense of biological images. |
Bio-IT World April 16, 2004 |
Portraits in Proteomics Advances in identifying protein biomarkers are spurring new hope in cancer diagnostics, expediting detection and easing testing. |
Bio-IT World June 17, 2004 John Russell |
Systems Biology - Now Leaving on Track 1 Entelos, a leader in predictive biosimulation, partners with pharmaceutical and biotech organizations worldwide to develop effective new treatments for disease. Michael French, chief business officer at Entelos, explains what powers the systems biology engine. |
BusinessWeek May 23, 2005 Catherine Arnst |
If It Works for Breast Cancer... Studies are under way to see if promising strategies used against breast cancer can be used to fight other killers, such as lung, colon, and prostate cancer. |
Science News May 19, 2007 |
Science Safari: Cancer Risk -- Understanding the Puzzle This new Web site from the National Cancer Institute cuts through the hype to help you understand the plain and simple truth about cancer risk. |
The Motley Fool October 27, 2006 Jack Uldrich |
Nanotech and the War on Cancer New imaging advances in nanotechnology will help speed cancers' end. What does it mean for investors? |
BusinessWeek December 12, 2005 Michael Arndt |
Cancer Cells With A Death Wish Is Abbott Labs' Stephen Fesik closing in on a way to make cancer cells self-destruct? |
Chemistry World July 28, 2009 Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
BusinessWeek June 16, 2011 Langreth & Cortez |
When Two Cancer Drugs Are Better Than One Drugmakers are collaborating to test combinations of genetically targeted cancer drugs in hopes of boosting survival rates. |