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Bio-IT World July 2005 John Russell |
Harvard Tackles Systems Biology Towards the end of this summer, researchers at the Virtual Cell Program expect to unleash b -- pronounced "little b" -- a new open-source computer language they hope will energize the biological modeling community as nothing has before. |
Bio-IT World September 2006 Nat Goodman |
Getting a Handle on Systems Biology Systems biology is squarely an experimental field that eats, drinks, and breathes data. To do systems biology, you need an experimental system that is amenable to large-scale experimentation. |
Bio-IT World December 15, 2003 Zachary Zimmerman |
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. |
Bio-IT World May 19, 2004 John Russell |
Seeing the Forest and the Trees A tiny clearing in the fog of systems biology. |
Chemistry World September 13, 2012 Andy Merritt |
Chemical biology comes of age Historically strongest in the US, chemical biology has become increasingly important worldwide, but for many years researchers at the chemistry -- biology interface have struggled to establish their discipline |
Bio-IT World January 21, 2005 |
Defining 'Integrative Genomics' Five experts from academia and industry discuss the burgeoning field of integrative genomics. |
Bio-IT World Dec 2006/Jan 2007 John Russell |
Novartis' Answer to Harry Potter Imagine a magic wand able to instantly materialize novel, safe, and effective drugs. No such device exists, of course, but Novartis has a distant cousin of sorts: the UltraLink is an immensely powerful text-mining tool and knowledge management platform. |
Bio-IT World September 2006 John Russell |
Informatics Cornucopia Predictive Informatics, the hopeful title of a session at last month's Drug Discovery Technology & Development World Congress, remains an enticing but mostly elusive goal. Asked what systems biology would look in five years and what will constitute success, panelists offered the following. |
Bio-IT World February 2006 John Russell |
Marvelous Models of Biological Systems Here are highlights from a roundtable discussion with researchers representing academia and pharmaceuticals, as well as executives from modeling technology providers on whether or not Pharma is ready to bet on computational modeling of biological systems. |
Bio-IT World September 9, 2002 |
Letters Frustrated in Gene Town... IT for the Biologists, by the Biologists?... |
Bio-IT World June 12, 2002 John Dodge |
All Systems Go at ISB The Seattle-based Institute for Systems Biology (ISB), takes a holistic view of genomic and proteomic research. The author spoke with its president, noted biologist Leroy Hood, recently to find out how far ISB has come in its two years of life. |
Bio-IT World September 2006 John Russell |
Predicting the Future of Systems Biology Buoyed by promising results from a recent collaboration with Pfizer on drug-induced vascular injury, Keith Elliston, CEO of modeling and biosimulation specialist Genstruct, offers a candid view of industry's flirtation with systems biology and the future prospects for the field. |
Bio-IT World November 12, 2002 Michael Goldman |
A Virtual Pharmacopeia Computational modeling of disease pathways, organs --- even patients --- could transform drug discovery. Does salvation exist in silico? |
Bio-IT World February 10, 2003 Salvatore Salamone |
Made in Manhattan A talk with the new head of the Computational Biology Center at Memorial Sloan-Kettering. |
Bio-IT World January 12, 2004 Julia Boguslavsky |
New Year Tools for the 'New' Biology Instrumentation outlook for systems biology. |
Bio-IT World February 2006 John Russell |
Preventable Vioxx Problems? Pathway analysis tools might have identified Vioxx's problematic off-target activity much earlier. Wondering which modeling approach to use for your project? |
Macworld December 2002 Charles Seiter |
Simulink 5 The engineer's best friend returns to the Mac. This program, which uses a built-in Matlab computational base to generate simulations from block diagrams, is the best tool available for simulation of mechanical control systems and digital signal processing. |
Bio-IT World August 15, 2005 Kevin Davies |
Pimp My Genome As costs plummet, the ability to rapidly synthesize and customize longer, more intricate fragments of genomic DNA opens up a plethora of applications in basic and applied biology. A commercial synthetic biology industry is beginning to take shape. |
Bio-IT World January 13, 2003 John Dodge |
Talent Fuels Drug Pipeline in Swiss Time The functional genomics group has emerged as a critical link in the drug discovery chain at Novartis Pharmaceuticals Corp. While it employs a multidisciplinary approach to drug discovery, the four-year-old group's goals could not be simpler: Find novel drug targets. |
Bio-IT World Dec 2006/Jan 2007 John Russell |
Setting the Systems Bio Syllabus An interview with David de Graaf about Pfizer's growing comfort with systems biology. |
Chemistry World May 1, 2014 Ned Stafford |
Synthetic biology vision for Europe unveiled A new 'strategic vision' for synthetic biology has laid out the steps Europe needs to take in the next five to 10 year to nurture the field, with chemistry a key part of its strategy. |
HHMI Bulletin Nov 2011 Robert Tjian |
President's Letter: Intellectual Ferment There are exciting connections between chemistry and biology from both "sides" of the disciplinary divide. |
Chemistry World January 2012 |
Cultivating collaboration A new network aims to bring the power of interdisciplinary innovation to bear on global food issues. |
Chemistry World July 2008 Ananyo Bhattacharya |
Sparks of creation Chemists are at the forefront of synthetic biology, the burgeoning field that could soon create artificial life. |
IEEE Spectrum March 2011 Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
Industrial Physicist Apr/May 2003 Jennifer Oullette |
Switching from physics to biology Physicists in transition help shape biological theory. |
Bio-IT World October 14, 2004 Zachary Zimmerman |
Follow the Pathway to Increased ROI Although this software has been commercially available for only a year, Ingenuity claims nine of the top 10 pharmaceutical companies as customers, including Pfizer, Wyeth, GlaxoSmithKline, and Aventis. |
Bio-IT World June 17, 2004 John Russell |
Systems Biology - Now Leaving on Track 1 Entelos, a leader in predictive biosimulation, partners with pharmaceutical and biotech organizations worldwide to develop effective new treatments for disease. Michael French, chief business officer at Entelos, explains what powers the systems biology engine. |
Bio-IT World December 15, 2003 Mark D. Uehling |
Model Patient Despite the FDA's new support for computational modeling, the pharmaceutical industry remains cautious about simulating clinical trials. |
Industrial Physicist Jennifer Ouellette |
Bioinformatics moves into the mainstream An explosion of data is being tamed with new systems |
Macworld December 2002 Charles Seiter |
Matlab 6.5 The MathWorks' Matlab has long been the preferred math program for many engineering uses. After several years' absence, the latest version, Matlab 6.5, brings it back to the Mac. |
HHMI Bulletin Nov 2011 Sarah C. P. Williams |
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. |
Chemistry World July 6, 2012 |
Protein power Tom Muir, professor of chemistry and molecular biology, Princeton University, US, is an expert in protein engineering and its application to studying cellular signalling networks. |
BusinessWeek August 12, 2010 Arielle Fridson |
Innovator: George Church Synthetic biologist George Church says he can create living things faster than nature can, essentially speeding up evolution. And he says he can do it cheaply. |
Bio-IT World November 2006 John Russell |
On the CASP of a DREAM A meeting to evaluate the results of the CASP (Critical Assessment of Techniques for Protein Structure Prediction) 7 predictions is scheduled for this month. |
Bio-IT World June 12, 2002 Beth Schachter |
Informatics Moves to the Head of the Class The race is on to increase the quantity and quality of bio-IT training programs as government and academia bet the need will be great. Will the job market back up that bet? |
HHMI Bulletin Nov 2011 Sarah C.P. Williams. |
Carolyn Bertozzi: Changed Expectations Chemists trained in biology were once a rarity -- now they're becoming the norm. |
Chemistry World |
Fishing for Chemical Answers to Biological Questions James K. Chen talks about chemical biology, his love for the outdoors and fly fishing. |
National Defense August 2006 Grace Jean |
Disjointed Defense Simulation Programs Prompt Reorganization The increasing demand for virtual training and war gaming has prompted the Defense Department to reorganize how it manages modeling and simulation. |