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Bio-IT World
Jul/Aug 2006
Deb Janssen |
Managing the Microarray Data Mountain Genomic studies often involve thousands of samples and require hundreds of thousands of assays per sample. Microarray manufacturers are scurrying to satisfy researcher demands for increased array density, sample number, and content flexibility.   |
Wired
June 2000
Brian Alexander |
Biopoly Money Patents and strong-arm tactics are helping make Affymetrix the Intel of biochips. Along the way, Affy wants to turn DNA into a proprietary system. |
Bio-IT World
October 10, 2003
Donna Mendrick |
Microarrays That Make Drugs Safe Using DNA chips to discover potential toxicity in new drug compounds -- a key application of toxicogenomics -- can predict adverse effects before they occur, enabling safer clinical trials. |
Bio-IT World
October 2006
Kevin Davies |
Microarray Platforms Shine DNA microarrays from the leading commercial sources are more reliably consistent than previously suspected, according to a new study. |
Bio-IT World
February 18, 2004 |
Just Bead It MPSS can help address the limitations of microarrays. |
Bio-IT World
December 10, 2002
Rotem Sorek |
Alternative Splicing: Listen to the Mouse The completed mouse genome may help to finally pin down the size of the transcriptome. |
Managed Care
August 2004
Thomas Morrow |
10,000 Cells on a Chip Signal Start of New Era of Diagnosis Diseases will soon be defined by biochemical pathways and genetic interactions. Biochips may identify patients likely to respond to therapeutic agents. All of this is a big deal for health plans. |
Bio-IT World
February 2007
Robert M. Frederickson |
Scramble for CodeLink Customers GE Healthcare has quietly announced that it will stop production of the popular CodeLink array system in 2007. The news was not a complete surprise to some users of the system who felt the company had been backing away from the platform. |
Bio-IT World
September 2006
Robert M. Frederickson |
Assays and Knowledgebases for Genomic Analysis An important aspect of any genomic analysis -- whether expression profiling or analysis of DNA-binding elements as above -- is the integration of the data with existing knowledge. |
Bio-IT World
April 15, 2003
Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
Wired
August 2000
Jennifer Hillner |
Area 22 The inside story of the first fully sequenced chromosome. |
Bio-IT World
January 13, 2003
Julia Boguslavsky |
A Sequel to the Sequence The all-but-complete human genome sequence is not only an indispensable tool for biomedical research but also a major influence on the types of instrumentation researchers will invest in. |
Chemistry World
January 11, 2008
John Bonner |
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. |
Bio-IT World
March 8, 2005
Kevin Davies |
DNA Chips Reveal Gene Activity Broad-Affymetrix collaboration examines chromatin and histone roles in gene regulation. |
Chemistry World
January 12, 2015
Emma Stoye |
Protein mutant libraries to probe diseases' genetic link quickly and cheaply Researchers in the US have developed a faster and less costly way to investigate the effects of genetic mutations on proteins, which should offer new insights into hereditary diseases. |
Bio-IT World
November 2005 |
News Blast Applied Biosystems contributes 400,000 primers... Researchers have discovered the full genetic sequence of many different strains of the flu... Sigma-Aldrich launches Panorama Human Cancer Version 1 Protein Functional Microarray... |
Bio-IT World
February 18, 2004 |
Proteomics Goes Cellular Tissue microarrays save big on sample material and reagents. But more importantly, this new high-throughput technology is helping save the lives of cancer patients |
Bio-IT World
April 15, 2003
Mark D. Uehling |
Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials. |
Wired
August 2003
Jennifer Kahn |
The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine. |
Bio-IT World
February 18, 2004 |
Pathology Goes Molecular New technologies are enabling clinical diagnostic laboratories to pave the way toward more personalized cancer therapies |
PC Magazine
July 13, 2005
John R. Quain |
DNA Printing Press A group of scientists believes it has an inexpensive nanoprinting technique that could lead to the mass production of DNA-based chips that could revolutionize disease detection. |
Bio-IT World
November 19, 2004
Kevin Davies |
The Book on Bioinformatics Research director David Mount talks about his new book "Bioinformatics: Sequence and Genome Analysis," sequence analysis, and teaching bioinformatics |
Bio-IT World
May 2006
Kevin Davies |
Interpreting Genes and Genomes From microarrays to sequencing technology, molecular diagnostics to the interactome, this year's Bio-IT World Conference showcased exciting advances in genome technology applications, in which software analysis and data management play critical roles. |
Salon.com
May 1, 2000
Arthur Allen |
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. |
Bio-IT World
February 10, 2003
Kevin Davies |
With a Click of the Mouse What do Eminem and Mus musculus have in common? About 30,000 genes, for a start. The author mulls over the second mammalian genome. |
Salon.com
February 13, 2001
Arthur Allen |
Size doesn't matter As scientists unveil the human genome findings, it turns out we have a lot fewer genes than we'd thought, and not many more than a fruit fly... |
Bio-IT World
August 15, 2005
Robert M. Frederickson |
What's 'Post' About Postgenomic? Bioinformatics tools can help organize and study genomic sequences that were discovered in the '90s. The tools help with tasks like analyzing gene expression, predicting protein structure and function, and establishing networks of interacting protein in cells. |
Bio-IT World
June 2005 |
New Products Unbeatable Spot Detection... The Power of Xmatrx... Little Dipper... Rapid Nucleic Acid Detection... Mass Spectrometer for Protein Biomarkers... Benchtop Solution for Clinical Proteomics... etc. |
Bio-IT World
July 14, 2004
Malorye A. Branca |
The Maven of Microarrays Affymetrix Research Institute's CEO, Stephen Fodor, discusses building a tech business without a blueprint |
Bio-IT World
September 11, 2003
Kevin Davies |
Chipping Away at Cancer In Vivo, In Situ Two studies probe new applications of DNA microarrays, revealing new insights into the pathogenesis and pharmacogenomics of cancer. |
Salon.com
June 27, 2000
Tabitha M. Powledge |
Book of life? Hosanna! The Human Genome Project has been completed. We will now cure diseases, weed out defective genes and create a new supergeneration in the near future. Not. |
Chemistry World
June 26, 2008
Bea Perks |
Liquid Crystals Stand up for DNA Detection Liquid crystals that realign in response to DNA can reveal subtle sequence alterations, even a single base mutation, report US scientists. |
Bio-IT World
September 2006
John A. Wass |
Integrating Knowledge The results of new mathematical routines have the potential to save pharmaceuticals millions of dollars in drug development. And yet the flow of successful drugs is dwindling. The problem goes beyond bureaucracy and lies in the complexity of the problem. |
Reason
Aug/Sep 2000
Ronald Bailey |
Strands of Life Book Review: Genome: The Autobiography of a Species in 23 Chapters, by Matt Ridley |
Chemistry World
April 27, 2006 |
Arrays Learn to Multitask Researchers have increased the information density of microarrays without further shrinking the dimensions of the spots. Instead, they used a combinatorial approach that involves multiple usage of each spot, known as multiplexing. |
Bio-IT World
June 17, 2004
Michael A. Goldman |
A Hip Approach to Gene Hunting IntegraGen defines the genetic blueprint of complex human diseases and delivers validated disease markers and therapeutic targets for a better diagnosis and a causal treatment of common diseases, based on its unique genomic analysis expertise. |
Bio-IT World
July 2005
Kevin Davies |
Medicine Gets Personal Touch More genomics-based drugs are moving into development with others, such as new cancer drugs showcasing on the clinical pharmacogenics scene as outlined in the Advances in Genomic Medicine program of a recent world conference. |
Reactive Reports
Apr/May 2005
David Bradley |
At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule. |
Bio-IT World
September 2005
Kristen Amuzzini |
A More Efficient Approach to Biostatistical Data Analysis Using an efficient, integrated approach, data from many different sources can easily be acquired, massaged to ensure its integrity, and then combined into single tables that biostatisticians can use to search for patterns regardless of the source of the data. |
PC Magazine
November 5, 2003 |
Bits & Bytes The entire human genome now exists on a chip... On the average, a typical corporate user receives 81 e-mails and sends 29 messages per day... Online retail sales in the U.S. have jumped in 2003... |
Bio-IT World
April 15, 2003
Robert M. Frederickson |
Protein Chemistry Surfaces Protein chips seek to do for protein expression profiling what DNA chips did for RNA expression. |
Fast Company
November 2009
David H. Freedman |
The Gene Bubble: Why We Still Aren't Disease-Free When the human genome was first sequenced nearly a decade ago, the world lit up with talk about how new gene-specific drugs would help us cheat death. Well, the verdict is in: Keep eating those greens. |
Bio-IT World
June 17, 2004
Robert M. Frederickson |
Microarray Analysis Reaches the Desktop Various commercial solutions exist to analyze microarray data, from enterprise-level solutions designed primarily for large companies and institute-based support facilities to the more recently emerged desktop solutions for individual research labs. |
Chemistry World
August 26, 2008
Fred Campbell |
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. |
Bio-IT World
January 21, 2005
Salvatore Salamone |
A Prescription for Information-Based Medicine TurboWorx president and CEO Jeff Augen not only combines computational and biology expertise, but also has a clear vision of how to advance life science discovery. |
Bio-IT World
November 14, 2003
Jeff Augen |
Making Information-Based Medicine Work A confluence of scientific discovery and high-throughput technology has made information-based medicine possible -- and imperative. |
Bio-IT World
December 15, 2003
Zachary Zimmerman |
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. |
Bio-IT World
June 15, 2003
Robert M. Frederickson |
Popular (Tissue) Culture Tissue microarrays are coming into their own as important histological screening tools. |
Bio-IT World
June 2006
Robert M. Frederickson |
Tissue Microarray Hard and Software Technological advances in automated microscopes, digital image acquisition, and high-throughput screening techniques have led to the need for more sophisticated software tools, now offered through a collaboration between DMetrix, BioImagene, IBM and the Arizona Cancer Center. |
Chemistry World
July 13, 2011
Hayley Birch |
Naked mole-rat genome holds clue to beating cancer The recently published draft sequence of the naked mole-rat genome promises to reveal the secrets of its long and remarkably cancer-free existence, potentially providing new targets for anti-cancer drugs. |
