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Bio-IT World
Jul/Aug 2006
Deb Janssen |
Managing the Microarray Data Mountain Genomic studies often involve thousands of samples and require hundreds of thousands of assays per sample. Microarray manufacturers are scurrying to satisfy researcher demands for increased array density, sample number, and content flexibility.   |
Bio-IT World
Jul/Aug 2006
John Russell |
NCI Awards $1.4M for Biomarker Software The Natonal Cancer Institute has awarded roughly $1.4 million to statistics software specialist Insightful to develop analytic methods and a software suite -- S+ Proteome -- for processing and analyzing protein mass spectra data. |
Bio-IT World
August 13, 2002
Malorye Branca |
The Proteomics Odyssey Efforts to map the constellation of protein interactions in humans gather momentum as companies vie to provide tools to capitalize on the potential of proteomics. But can proteomics prevail where some feel genomics has failed? |
Industrial Physicist
Aug/Sep 2003
Ineke Malsch |
Protein research calls for advanced instruments The science of protein interactions is becoming a major tool in biomedical and drug development research. Carrying out and advancing such studies more efficiently and effectively, however, will require new, cutting-edge instrumentation. |
Bio-IT World
April 15, 2003
Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
Bio-IT World
July 11, 2002
Malorye Branca |
Deep Sequence Diving Like sailors of old, genomic data miners dream of discovering riches and fame. Given the recent improvements in analytics -- and a little more time -- they just might succeed. |
Bio-IT World
July 14, 2004
Karen Hopkin |
'Omics: The NextGeneration Researchers in industry and academia are cataloging collections of biochemical compounds (metabolomics) to determine how they respond when organisms are challenged by drugs, disease, or stress (metabonomics). |
Bio-IT World
October 10, 2003
Donna Mendrick |
Microarrays That Make Drugs Safe Using DNA chips to discover potential toxicity in new drug compounds -- a key application of toxicogenomics -- can predict adverse effects before they occur, enabling safer clinical trials. |
Chemistry World
July 24, 2013 |
Spectrometry for the masses A mass spectrometer ionizes chemical compounds to generate charged molecules or molecular fragments and allows the measurement of the molecular mass of a sample. Mass spectrometry continues to move forward, shaping new scientific fields in the process. |
Bio-IT World
November 19, 2004
John Russell |
Sourcebook: Matters of Interpretation Michael O'Connell talks about trends in microarray and mass-spec data analysis and Insightful Corp.'s recent deal with visualization specialist Spotfire. |
Bio-IT World
February 18, 2004 |
Just Bead It MPSS can help address the limitations of microarrays. |
Bio-IT World
July 15, 2003 |
Millennium's PARIS Illuminates Pathways To address high-throughput-data challenges, Millennium Pharmaceuticals built the PAthway Resource and Information System, or PARIS -- a unique platform for combining knowledge from heterogeneous data sources in the construction of a pathway knowledgebase. |
Wired
August 2003
Jennifer Kahn |
The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine. |
Bio-IT World
November 19, 2004
Kevin Davies |
The Book on Bioinformatics Research director David Mount talks about his new book "Bioinformatics: Sequence and Genome Analysis," sequence analysis, and teaching bioinformatics |
Bio-IT World
October 10, 2003
Mel Kronick |
In Situ Chips on Demand Microarray manufacturing technologies are giving new meaning to the term 'custom.' |
Bio-IT World
October 2006
Kevin Davies |
Microarray Platforms Shine DNA microarrays from the leading commercial sources are more reliably consistent than previously suspected, according to a new study. |
Bio-IT World
July 14, 2004
Malorye A. Branca |
The Pathways Promise By using the right tools, even a modest genomic data set can generate a good view into a particular biological pathway. Now, a range of new technologies is arising from academia as well as the commercial sector to meet this need. |
Bio-IT World
July 2005 |
New Products HyperSense Makes Sense... BINDing Interactions for Drug Discovery Applications... Images of a GeneGnome... Low-Volume Cell: High Conversion... Arrayjet Takes Off with Microarray Spotter... |
Bio-IT World
June 2006
Kevin Davies |
The Data Deluge: Deal or No Deal? Far from decrying the data glut, researchers should embrace the complexity of genomic and other sources of data, particularly for its predictive properties in the field of personalized medicine. |
Bio-IT World
July 2005
Robert M. Frederickson |
Amassing Mass Spectrometry Tools Mass spectrometry is a key tool in the effort to identify protein biomarkers of human disease. Manufacturers have met major challenges in adapting this technology to protein discovery, both qualitatively and quantitatively. |
Bio-IT World
June 17, 2004
Robert M. Frederickson |
Microarray Analysis Reaches the Desktop Various commercial solutions exist to analyze microarray data, from enterprise-level solutions designed primarily for large companies and institute-based support facilities to the more recently emerged desktop solutions for individual research labs. |
Bio-IT World
June 12, 2002
John Dodge |
All Systems Go at ISB The Seattle-based Institute for Systems Biology (ISB), takes a holistic view of genomic and proteomic research. The author spoke with its president, noted biologist Leroy Hood, recently to find out how far ISB has come in its two years of life. |
Bio-IT World
September 11, 2003
Kevin Davies |
Chipping Away at Cancer In Vivo, In Situ Two studies probe new applications of DNA microarrays, revealing new insights into the pathogenesis and pharmacogenomics of cancer. |
Chemistry World
January 9, 2014 |
Spinning into focus NMR is used by big industry, and scientists in pharmaceutical companies, for example, have appreciated the benefits of NMR spectroscopy for years. It reveals the structure of molecules in a sample, providing more information than some other analytical techniques. |
Chemistry World
May 5, 2011
Simon Hadlington |
Revolutionary new single-cell labelling method Researchers in the US and Canada have combined mass spectrometry with a technique called flow cytometry to follow dozens of biochemical markers on individual cells simultaneously. |
Chemistry World
December 23, 2015 |
Bones of contention Can protein in dinosaur bones survive for millions of years? Rachel Brazil explores the evidence. |
Bio-IT World
May 2006
Kevin Davies |
Interpreting Genes and Genomes From microarrays to sequencing technology, molecular diagnostics to the interactome, this year's Bio-IT World Conference showcased exciting advances in genome technology applications, in which software analysis and data management play critical roles. |
Bio-IT World
September 2006
Robert M. Frederickson |
Assays and Knowledgebases for Genomic Analysis An important aspect of any genomic analysis -- whether expression profiling or analysis of DNA-binding elements as above -- is the integration of the data with existing knowledge. |
Bio-IT World
May 2006
Robert M. Frederickson |
A New (Bio)Spin on NMR Applications Bruker BioSpin recently announced several introductions to improve throughput, sensitivity, and versatility of its systems for nuclear magnetic resonance applications starting with the SampleJet, a robotics system for high-throughput transfers of NMR sample tubes into the NMR spectrometer. |
Bio-IT World
May 7, 2002
Eric Fairfield |
Bridging the Language Barrier In the market segments where biologists and IT professionals have primarily interacted to date, there has been little need for common definitions. But the next generation of bio-IT products will require some shared definitions between IT and biology -- simplified cross-disciplinary languages. |
Bio-IT World
June 12, 2002
Mark D. Uehling |
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? |
Bio-IT World
November 2005 |
News Blast Applied Biosystems contributes 400,000 primers... Researchers have discovered the full genetic sequence of many different strains of the flu... Sigma-Aldrich launches Panorama Human Cancer Version 1 Protein Functional Microarray... |
Bio-IT World
September 2005
Stephen Langdell |
Data Mining and the Euredit Project The multimillion-dollar, EU-funded research project on statistical methods for data mining, is creating interesting possibilities for many bioinformatics endeavors, including microarray analysis and forecasting trends. |
Managed Care
August 2007
Thomas Morrow |
Gene Expression Microarray Improves Prediction of Breast Cancer Outcomes Flash-frozen samples of surgically removed breast cancer tissue are the key to measuring a patient's risk of metastasis. |
Chemistry World
October 15, 2012
Melissae Fellet |
Synthesis by mass spectrometry Chemists have used mass spectrometry, commonly used to analyze molecules, to synthesize them on the microscale. |
Bio-IT World
April 15, 2003
Mark D. Uehling |
Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials. |
Salon.com
February 13, 2001
Arthur Allen |
Size doesn't matter As scientists unveil the human genome findings, it turns out we have a lot fewer genes than we'd thought, and not many more than a fruit fly... |
