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HHMI Bulletin
February 2011
Michele Solis
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. mark for My Articles similar articles
Chemistry World
December 21, 2006
Henry Nicholls
Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper. mark for My Articles similar articles
Chemistry World
August 26, 2008
Fred Campbell
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. mark for My Articles similar articles
Chemistry World
November 13, 2014
Katrina Kramer
Persuading proteins to form porous polyhedra Researchers in the US have designed a hollow cube out of naturally occurring proteins, something that was previously only possible with DNA. mark for My Articles similar articles
HHMI Bulletin
May 2012
Sarah C. P. Williams
Opening the Floodgates Researchers are using exome sequencing -- zeroing in on the genes that encode proteins -- to explore the biology of certain diseases. mark for My Articles similar articles
HHMI Bulletin
Fall 2012
Ingfei Chen
Same But Not Equal A code within the genetic code explains why identical proteins are produced at varying speeds. mark for My Articles similar articles
Bio-IT World
November 2005
News Blast Applied Biosystems contributes 400,000 primers... Researchers have discovered the full genetic sequence of many different strains of the flu... Sigma-Aldrich launches Panorama Human Cancer Version 1 Protein Functional Microarray... mark for My Articles similar articles
Chemistry World
October 8, 2008
Sarah Houlton
Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures. mark for My Articles similar articles
Technology Research News
March 24, 2004
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. mark for My Articles similar articles
HHMI Bulletin
Nov 2010
Sarah C.P. Williams
Scientists Track Down Genetic Mutations In Record Time Scanning the human genome for a single disease-causing mutation is like taking a copy of War and Peace in a foreign language and searching for one misspelled word mark for My Articles similar articles
Chemistry World
June 7, 2007
Jessica Ebert
Sensitive Sequencing Technique for Early Diagnosis A new technique, with sensitivity unmatched by current technologies, can detect changes in gene transcription that occur during the course of a disease, report US researchers. mark for My Articles similar articles
HHMI Bulletin
Aug 2010
Joaquin Espinosa's fresh look at p53 Even though it was discovered more than 25 years ago, and many more tumor suppressor genes have been found since, p53 remains the big one. It's mutated in about 50 percent of tumors. mark for My Articles similar articles
Chemistry World
April 27, 2006
`Sticky Trees' Glue Molecules to Proteins Researchers have developed a chemical glue that binds molecules to proteins without compromising protein function. The method could be used to modify a wide range of proteins for a variety of purposes, such as in the development of new protein-based therapies. mark for My Articles similar articles
Chemistry World
November 27, 2013
Jennifer Newton
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. mark for My Articles similar articles
Chemistry World
August 26, 2014
Andy Extance
No-frills coats set a trend for designer viruses Dutch scientists have built a simple model of viruses' protective coats in an attempt to create viral mimics that could fight diseases, as opposed to causing them. mark for My Articles similar articles
PC Magazine
July 13, 2005
John R. Quain
DNA Printing Press A group of scientists believes it has an inexpensive nanoprinting technique that could lead to the mass production of DNA-based chips that could revolutionize disease detection. mark for My Articles similar articles
Chemistry World
August 3, 2009
Simon Hadlington
Computational chemistry predicts flu mutations Researchers in the US have shown how it might be possible to use computational chemistry to predict which mutations in a key influenza virus protein could lead to dangerous new strains of the disease. mark for My Articles similar articles
IEEE Spectrum
March 2011
Lucks & Arkin
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering mark for My Articles similar articles
HHMI Bulletin
Feb 2011
DNA Curtains How proteins behave in such a crash test gives scientists data about their structural integrity, how they attach to DNA, and how they behave in a cell. mark for My Articles similar articles
Pharmaceutical Executive
November 1, 2006
Thoughtleader: Making Things Stick Ambrx has created the "glue" that allows researchers to attach activity-enhancing molecules to amino acids where they couldn't before. mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Dave Mosher
A New PACE for Laboratory Evolution Researchers have found a way to accelerate evolution of molecules by harnessing viruses. mark for My Articles similar articles
Chemistry World
July 16, 2009
James Urquhart
New DNA technique sheds light on ancient populations A new sequencing technique that is cheaper and less wasteful has been used to decode and analyse the mitochondrial genomes of five Neanderthal individuals. mark for My Articles similar articles
Chemistry World
January 30, 2014
Anthony King
Unnatural DNA links click for faster synthesis Human cells can still read strands of DNA correctly if they are stitched together using linkers not found in nature, a new study shows. mark for My Articles similar articles
Chemistry World
June 26, 2008
Bea Perks
Liquid Crystals Stand up for DNA Detection Liquid crystals that realign in response to DNA can reveal subtle sequence alterations, even a single base mutation, report US scientists. mark for My Articles similar articles
Chemistry World
February 18, 2008
John Bonner
Flicking the Acetyl Switch A strain of Escherichia coli that can produce proteins containing an acetylated version of the amino acid lysine could help to reveal how acetylation changes the function of hundreds of proteins inside cells. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Mel Kronick
In Situ Chips on Demand Microarray manufacturing technologies are giving new meaning to the term 'custom.' mark for My Articles similar articles
Chemistry World
September 17, 2012
Ian Le Guillou
Raising the curtain on single-stranded DNA Scientists have created microfluidic devices containing single-stranded DNA 'curtains' for the first time, allowing scientists to study its interactions with proteins in real time. mark for My Articles similar articles
Chemistry World
June 2, 2015
Tim Wogan
Simple sensor can spot cancer markers in minutes An electrochemical sensor that can detect specific mutant nucleic acids from cancers in blood samples could allow quick and cheap 'liquid biopsies'. mark for My Articles similar articles
Chemistry World
January 11, 2008
John Bonner
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Jeffrey Skolnick
Protein Structure Prediction in Drug Discovery Indications are that structure prediction can assist in the automated assignment of proteins to known pathways. mark for My Articles similar articles
Chemistry World
February 3, 2013
Andy Extance
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. mark for My Articles similar articles
Chemistry World
October 6, 2014
Emma Stoye
BRCA2 protein imaged for first time The first detailed images of BRCA2 -- have revealed its structure and the mechanism by which it works, offering hope for new treatments. mark for My Articles similar articles
HHMI Bulletin
February 2011
Sarah C.P. Williams
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. mark for My Articles similar articles
Managed Care
November 2003
Thomas Morrow
Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Malorye Branca
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? mark for My Articles similar articles
Bio-IT World
June 12, 2002
Mark D. Uehling
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? mark for My Articles similar articles
Chemistry World
October 19, 2015
Matthew Gunther
The house that DNA built The 2015 chemistry Nobel prize was awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar for DNA repair. mark for My Articles similar articles
Chemistry World
June 1, 2012
Simon Hadlington
Protein architecture with atomic precision Researchers have made a key breakthrough in designing and building geometrically defined nanostructures from proteins with unprecedented accuracy. mark for My Articles similar articles
Chemistry World
June 2, 2006
Jon Evans
Axons Get Directions Scientists are a step closer to understanding the processes that control the growth and spread of nerve cells, following the discovery of a protein complex that directs the transport of building material to growing axons. mark for My Articles similar articles
BusinessWeek
June 13, 2005
John Carey
The NIH's Roadmap for Research Charting the human genome was just the beginning. Now the focus is creating pathways that will lead to practical applications. mark for My Articles similar articles
Chemistry World
May 11, 2011
Laura Howes
Small molecule hope for muscular dystrophy Prompted by the case of a small boy who ought to have muscular dystrophy but doesn't, Japanese researchers have discovered a small molecule that they hope will treat the disease. mark for My Articles similar articles
Chemistry World
May 12, 2008
Simon Hadlington
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. mark for My Articles similar articles
Chemistry World
March 1, 2011
Catherine Bacon
Unravelling chromosomes Danish scientists have used a micro device to isolate centimetre-long portions of human DNA to help study the genetic make-up of diseased cells. mark for My Articles similar articles
Chemistry World
August 2007
Philip Ball
Opinion: The Crucible The twist on DNA mark for My Articles similar articles
Chemistry World
October 27, 2014
Tim Wogan
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. mark for My Articles similar articles
Chemistry World
July 2010
Anna Lewcock
Medicine made to measure Healthcare tailored to suit the genetic makeup of the patient is finally coming to fruition. mark for My Articles similar articles
Bio-IT World
June 12, 2002
Karen Hopkin
Computational Biologists Join the Fold CASP5 competitors compare the best algorithms for modeling the 3-D structure of proteins -- an exercise that could lead to new insights into the pathogenesis and treatment of disease. mark for My Articles similar articles
Salon.com
December 19, 2000
Carolyn McConnell
"The Century of the Gene" by Evelyn Fox Keller A new book argues that there may be no such thing as a gene. At least, it has proved very difficult to isolate a discrete physical item that can do the work our notion of the gene does... mark for My Articles similar articles
HHMI Bulletin
May 2011
Sarah C.P. Williams
The Pace of Evolution A close look at the human genome shows the slow and steady beat of adaptation. mark for My Articles similar articles
Chemistry World
October 13, 2015
Simon Hadlington
DNA movement through motor proteins measured Researchers have adapted a method for DNA sequencing to measure directly and with exquisite sensitivity the movement of a single molecule of DNA as it is drawn through specialized motor proteins. mark for My Articles similar articles