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HHMI Bulletin May 2010 Sarah C.P. Williams	Lab-Grown Liver New cell culture system solves problem of growing liver cells.
Chemistry World December 2, 2010 James Urquhart	Micro organ system to test cancer drugs Japanese researchers have created an organ-on-a-chip system that simultaneously tests how liver, intestine and breast cancer cells respond to cancer drugs.
Chemistry World April 24, 2013 Helen Bache	3D microfluidic liver on a chip Researchers have developed a three-dimensional liver model that can recreate cell signalling within the organ. The liver on a chip could cut tests on animals by providing an accurate artificial model of how the organ responds to new drugs.
Chemistry World February 12, 2012 Jon Cartwright	Nanoparticles slow iron absorption in the gut Nanoparticles used in food and pharmaceuticals could have unintended physiological effects.
Chemistry World March 9, 2009 Lewis Brindley	Finding the Risks of Nanoparticle Exposure A new model for nanoparticle exposure should provide more realistic insights into the possible health risks of airborne nanoparticles, researchers in Switzerland claim.
Chemistry World January 16, 2014	The art of alternatives Recent years have seen great advances in alternatives to animal tests. Yet we still need to understand how and why compounds are toxic before we can make the giant leap to replacement.
Chemistry World January 12, 2011 Amaya Camara-Campos	Artificial intestine for gut studies Three-dimensional hydrogel scaffolds for studying cells under realistic physiological conditions have been made by scientists from the US and Korea to study drug absorption in the gut.
Chemistry World July 26, 2010 Phillip Broadwith	Predicting nanoparticle toxicity Judging nanoparticle toxicity could be made easier by a new theoretical model that predicts which materials will make nanoparticles that could damage living cells. The model can predict the available electronic energy levels in the nanoparticle structure
HHMI Bulletin Aug 2010 Richard Saltus	Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch.
HHMI Bulletin Winter 2013 Jennifer Michalowski	A Happy Oasis The usually tranquil space of HHMI investigator Sangeeta Bhatia's office at the Massachusetts Institute of Technology fills with energy as her team gathers in two groups -- liver researchers first, then the cancer team.
Chemistry World February 14, 2011 Rachel Cooper	Small and sensitive nanoparticles A new highly sensitive nanoparticle contrast agent for imaging in the body stays in the bloodstream longer and is better at targeting tumors than other nanoparticle contrast agents, say Chinese scientists.
Chemistry World March 26, 2014 Katia Moskvitch	Nanoparticle sensors detect drug damage in the liver Stanford University researchers have created nanoparticle-based sensors that can image metabolites in animal livers, which they say could help eliminate toxic drug candidates before they are given to humans.
Chemistry World February 4, 2011 Harriet Brewerton	Transplant tracking Magnetic nanoparticles could be used to track neural stem cells after a transplant in order to monitor how the cells heal spinal injuries, say UK scientists.
Chemistry World December 3, 2013 Simon Hadlington	Caged toxin for safer, better bacterial vaccines Researchers in the US have developed a new way of vaccinating against bacterial toxins by caging them in hybrid nanoparticles.
Chemistry World September 11, 2013 Emma Stoye	Call to overhaul liver toxicity testing Outdated assays for monitoring liver health could have caused dozens of drug candidates to be wrongly scrapped during development, according to new research.
Chemistry World October 7, 2015 Christopher Barnard	Microfluidic device lets the drop beat Scientists in Switzerland have incorporated pulsing human heart tissue into a microfluidic device to make a model of a living system that could be used to test new drugs.
Chemistry World January 17, 2011 Laura Howes	Nanoparticle divides to conquer Scientists have made a nanoparticle that breaks up into smaller units once it reaches its target, allowing it to penetrate deeper into tumour tissue and deliver treatment more effectively.
Chemistry World June 28, 2009 Jon Cartwright	Antimicrobial nanoparticles may help fight brain infections Antimicrobial nanoparticles that can cross the, almost impermeable, blood-brain barrier have been created by Asian researchers.
National Defense March 2008 Grace V. Jean	Creating the Body's Microenvironment to Grow Artificial Organs Scientists are using micro-electromechanical systems to grow artificial organs.
Chemistry World July 1, 2012 Mellisae Fellet	3D printed sugar network to feed engineered organs US researchers can build vessels into a cell-containing gel -- the beginnings of a thick tissue. Scientists form the gel around a lattice of printed sugar fibers. The fibers dissolve after the gel sets, leaving a network of channels that carry nutrients like blood vessels.
Chemistry World October 7, 2012 David Bradley	Magnetic nanoparticles zap cancer Nanoparticles can be used as a remote-controlled magnetic death switch to kill cancer cells, according to researchers from Korea.
Chemistry World November 4, 2015 Suzanne Howson	Oral delivery of anticancer drug Scientists in China have unveiled a way to deliver a platinum-based anticancer drug orally.
Chemistry World April 7, 2009 Lewis Brindley	Cells get in line Magnetic nanoparticles that 'shepherd' cells into neat lines have been designed by American scientists.
Chemistry World January 5, 2011 Hayley Birch	Nanoparticles build up New research suggests that nanomaterials that are released into the environment could accumulate in food chains.
Chemistry World April 9, 2015	Big problems with little particles? There is a risk that poor toxicology studies could start undermining the success of nanomaterials.
Technology Research News July 27, 2005	Baited molecule fights cancer Many teams of researchers are working on ways to use nanotechnology to deliver anticancer drugs directly to cancerous tissue.
The Motley Fool November 9, 2004 Charly Travers	Are Stem Cells a Rule Breaker? Does the science offer real hope or just hype? Biotech investors take on enough risk in the normal course of drug development that they do not need to worry about whether or not the underlying technology even works.
Chemistry World March 21, 2010 Simon Hadlington	Nanoparticles successfully deliver RNA interference in cancer patients The system aims to exploit the phenomenon of RNA interference, where short sequences of double-stranded RNA, called small interfering RNA or siRNA, can trigger the disruption of the manufacture of certain proteins in a cell.
Chemistry World April 2010	Column: The crucible We are getting better at manipulating cells to grow into the tissues we need. Chemical factors are key, says Philip Ball
Chemistry World May 13, 2009 Lewis Brindley	Combination nanoparticles to fight cancer Korean chemists have assembled a multitalented nanoparticle that can hunt down, treat, and illuminate cancerous cells.
Chemistry World March 31, 2006 Bea Perks	Nanoparticle Drug Delivery Biodegradable polymers being developed the U.S. offer numerous advantages over current drug delivery systems, say researchers working on ways to deliver anti-inflammatory drugs directly into cells.
IEEE Spectrum February 2005 Carol Ezzell Webb	The Body Shops Part human, part machine, replacement organs may one day extend your life
Chemistry World June 27, 2010 Simon Hadlington	Nanoparticles allow remote control of cells In an experiment reminiscent of the mind-control rays that featured prominently in B-movies from the 1950s, scientists in the US have used a magnetic field to alter the behavior of an animal.
Chemistry World February 13, 2006	Nanoparticles Detect Cell Suicide Plans Researchers have developed a nanotechnological assay for detecting programmed cell death. The technique is effective in cell cultures, they report, and might eventually be used in humans.
Chemistry World July 9, 2013 Daniel Johnson	Stealthy nanoparticles gather to take on tumors A team of Chinese scientists have created nanoparticles that respond to changes in pH, clumping together in acidic conditions.
Chemistry World April 28, 2008 Victoria Gill	Gene silencing gets fat A team of researchers in the US has developed fat-like nanoparticles that can carry fragments of RNA into cells, bring treatments based on gene silencing a step closer.
Chemistry World January 2, 2015 Thadchajini Retneswaran	Smart nanoparticles take aim at cancer cells Scientists in China have developed an intelligent nanoparticle system that delivers a chemotherapeutic and radiosensitizer drug directly to the nucleus of cancer cells.
Technology Research News July 30, 2003 Kimberly Patch	Fractals support growing organs A method for making intricate networks of artificial blood vessels brings the decades-old dream of growing replacement organs a big step closer. The networks are designed to provide the support structure needed for organ cells to coalesce into something greater than the sum of its parts.
Technology Research News May 4, 2005 Eric Smalley	Chip Gauges Cell Reactions Researchers have devised a way to test within minutes the reactions of cells to all types of stimuli. The researchers' system is very sensitive, relatively inexpensive, uses little power, and is portable.
Chemistry World August 16, 2006 Michael Gross	Nanoparticle Toxicity Tested The rapid advance of nanotechnology has raised concerns that substances known to be harmless in bulk might turn out toxic or carcinogenic in certain fibrous or nanoparticle forms.
Chemistry World September 23, 2008 Simon Hadlington	Nanoparticles Hide Behind Protein Cloak Polymer nanoparticles suspended in human blood become cloaked in plasma proteins, new research has shown.
Chemistry World August 2009 Philip Ball	Column: The crucible Zinc nanoparticles appear to have the ability to make odorants smell stronger and could a give a valuable insight into how olfaction works
Chemistry World November 10, 2006 Victoria Gill	Healing Threads Spun From Living Cells Researchers have successfully made microthreads from polymers containing living cells, using a technique called electrospinning. These biologically active threads could be formed into medical scaffolds, to deliver cells directly to tissue and promote healing.
Chemistry World February 3, 2011 Hayley Birch	Nanoparticle studies guide coating design A new study provides guidance for designing nanoparticle coatings based on the particles' size and the environment they are to be used in. The research could help scientists create more effective nanoparticle drug carriers.
Chemistry World March 16, 2009 Hayley Birch	Nanodumbbells Target Cancer Cells US scientists have designed nanoparticles that function like 'guided missiles' in the targeted destruction of breast cancer cells.
Chemistry World March 6, 2006 Jon Evans	Nanoprobes Light up Cellular Demolition Researchers have developed a method for detecting and imaging programmed cell death (apoptosis). The method, involving polymer nanoparticles, could be used to diagnose apoptosis-related diseases and inform drug development.
Chemistry World April 11, 2006 Jon Evans	Nanotechnology Tackles Chemotherapy Chemists and medical researchers have developed nanoparticles that target chemotherapy drugs directly at tumours. The researchers claim that the same technique could be used to develop nanoparticle-based treatments for a wide range of other diseases.
Chemistry World June 19, 2012 Anthony King	Nanoparticles linked to rheumatoid arthritis Three types of nanoparticles were found to ramp up protein citrullination in cell cultures, a change that can make the body think native proteins are foreign. This process has previously been linked to autoimmune disease.
Chemistry World April 5, 2007 Lionel Milgrom	Nanoparticles Make Better MRI Images Manganese oxide nanoparticles have been used as contrast agent for magnetic resonance imaging, allowing researchers to see inside living brains in the same detail as dissected tissue under a microscope.
Chemistry World February 13, 2013 Michael Parkin	Bone-repairing nanoparticles laced with DNA A bone-repairing nanoparticle paste has been developed that promises faster repair of fractures and breakages. DNA containing two growth-factor genes is encapsulated inside synthetic calcium-phosphate nanoparticles.