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American Family Physician
March 15, 2005
Paul T. Giboney
Mildly Elevated Liver Transaminase Levels in the Asymptomatic Patient Mild elevations in liver chemistry tests can reveal serious underlying conditions or have transient and benign etiologies. If elevations persist after an appropriate period of observation, further testing may include ultrasonography and other serum studies. mark for My Articles similar articles
The Motley Fool
February 11, 2010
Brian Orelli
A Wonder Drug With Not-So-Wonderful Side Effects Wonder drug or not, Isis Pharmaceuticals and Genzyme's cholesterol drug mipomersen's sales will be limited by side effects. mark for My Articles similar articles
The Motley Fool
November 18, 2009
Brian Orelli
Drug Lowers Cholesterol; Stock Follows ISIS has a hard time at American Heart Association despite good efficacy data. mark for My Articles similar articles
Chemistry World
July 2010
Anna Lewcock
Medicine made to measure Healthcare tailored to suit the genetic makeup of the patient is finally coming to fruition. mark for My Articles similar articles
The Motley Fool
December 16, 2011
Brian Orelli
Safety (Still) Trumps Acquisitions in Hep C Pharmasset announced it was discontinuing all treatment arms in one of its phase 2b trials that contain the drug PSI-938. The drug candidate caused laboratory abnormalities in tests associated with liver function. mark for My Articles similar articles
BusinessWeek
September 5, 2005
Capell & Arndt
Drugs Get Smart Future medicines will more effectively target what ails you by tailoring treatment to your specific genetic profile. Personalized medicine will also help prevent another Vioxx. mark for My Articles similar articles
The Motley Fool
August 5, 2010
Brian Orelli
Blockbuster Efficacy! Not-So-Blockbuster Safety! Isis and Genzyme's wonder drug has not-so-wonderful side effects. Still. mark for My Articles similar articles
The Motley Fool
September 28, 2007
Brian Orelli
Side Effects No Match for This Tag Team Seven large drugmakers have come together to try and find genetic variations that cause medications to have serious side effects in some patients, but not in others. mark for My Articles similar articles
Pharmaceutical Executive
September 1, 2005
Mattingly & Saxberg
Biomarkers Come of Age In the past five years, biomarkers have become an essential part of pharmaceutical R&D. Seven industry experts explain how it happened - and what comes next. mark for My Articles similar articles
Chemistry World
November 2008
Derek Lowe
Column: In the pipeline Drug discovery chemists live by assay data; we depend on these numbers to tell us if we're heading in the right direction with our molecules. mark for My Articles similar articles
The Motley Fool
October 3, 2007
Brian Orelli
Big Pharma Loves Your Liver Three big pharma companies, AstraZeneca, GlaxoSmithKline, and Roche, are funding a stem-cell consortium. Investors, take note. mark for My Articles similar articles
Chemistry World
November 2006
Derek Lowe
Opinion: In the Pipeline Is there a way to kill off bad drug candidates before companies invest valuable time and money and in them? mark for My Articles similar articles
Chemistry World
January 16, 2014
The art of alternatives Recent years have seen great advances in alternatives to animal tests. Yet we still need to understand how and why compounds are toxic before we can make the giant leap to replacement. mark for My Articles similar articles
American Family Physician
June 1, 2006
Nonalcoholic Fatty Liver Disease: What You Should Know A patient guide: What is nonalcoholic fatty liver disease (NAFLD)?... How can my doctor tell if I have NAFLD?... What can I expect?... etc. mark for My Articles similar articles
American Family Physician
June 1, 2006
Bayard, Holt & Boroughs
Nonalcoholic Fatty Liver Disease Nonalcoholic fatty liver disease is a common condition associated with metabolic syndrome. It is the most common cause of elevated liver enzymes in U.S. adults, and is diagnosed after ruling out other causes of steatosis, particularly infectious hepatitis and alcohol abuse. mark for My Articles similar articles
Bio-IT World
August 13, 2003
John Rhodes
Beyond the Blockbuster Genomics and big hits are not mutually exclusive, writes Deloitte & Touche's life sciences expert. mark for My Articles similar articles
The Motley Fool
August 24, 2007
Brian Orelli
Take Your Medicine; Earn Your Profits Personalized medicine offers investment ideas. Let's take a look at what this new catchphrase in the medical community actually means, and how investors can benefit from it. mark for My Articles similar articles
BusinessWeek
September 5, 2005
Putting the FDA Out Front Deputy Commissioner Dr. Janet Woodcock explains how the agency has led the drive for personalized medicine. mark for My Articles similar articles
American Family Physician
September 1, 2006
Heidelbaugh & Bruderly
Cirrhosis and Chronic Liver Failure: Part I. Diagnosis and Evaluation Part I of a two-part on how to diagnose and determine treatment for cirrhosis and chronic liver failure. mark for My Articles similar articles
The Motley Fool
June 20, 2008
Brian Orelli
Live From Bio: Personalized Medicine The movement is chugging along thanks to diagnostics. mark for My Articles similar articles
The Motley Fool
April 17, 2008
Brian Lawler
The End for (Another) Hepatitis C Drug Candidate ViroPharma stops development of its compound after data showed it may hurt the liver. mark for My Articles similar articles
Nurse Practitioner
July 2008
Lynn A. Kelso
Cirrhosis: Caring for Patients with End-stage Liver Failure Caring for patients with end-stage liver disease can be very challenging for NPs. mark for My Articles similar articles
The Motley Fool
September 7, 2007
Brian Orelli
Clinical Data Gets Personal Clinical Data's lead compound Vilazodone posts strong phase 3 results. The company is searching for common genetic markers among patients who responded positively to the drug. mark for My Articles similar articles
Chemistry World
December 22, 2006
Victoria Gill
Metabolic Profiling Could Improve Animal Experiments Different types of rats respond to drugs in substantially different ways that can be tracked by metabolic analysis, according to scientists who say their finding has major implications for designing animal experiments. mark for My Articles similar articles
Bio-IT World
February 18, 2004
Pathology Goes Molecular New technologies are enabling clinical diagnostic laboratories to pave the way toward more personalized cancer therapies mark for My Articles similar articles
HHMI Bulletin
Fall 2012
Sarah C. P. Williams
The Fat You Can't See Without the liver acting as a filter and energy producer, a person can't survive, and no artificial organ can perform all of its duties. But in one in three Americans -- and similar numbers in other developed nations -- the liver has lost its luster. mark for My Articles similar articles
HHMI Bulletin
May 2010
Sarah C.P. Williams
Lab-Grown Liver New cell culture system solves problem of growing liver cells. mark for My Articles similar articles
The Motley Fool
September 27, 2007
Brian Lawler
ViroPharma's Good Bad News The prospects for ViroPharma's HCV-796 darkened significantly after the company reported troubling clinical results, however, there's still hope for the compound. Investors, take note. mark for My Articles similar articles
Managed Care
November 2006
Maureen Glabman
Genetic Testing: Major Opportunity, Major Problems Whether a person is likely to develop diabetes, cancer, schizophrenia, or stroke will be reasonably well predicted, and tests can also determine whether a patient will respond to a given therapy. That's the good part. mark for My Articles similar articles
Chemistry World
July 24, 2007
Richard Van Noorden
A Viable Alternative Tests on mice, rats, rabbits and guinea pigs to stop harmful chemicals reaching humans were once a necessary evil. But such checks now seem embarrassingly old-fashioned, according to a report on toxicity testing. mark for My Articles similar articles
American Family Physician
January 15, 2004
Roche & Kobos
Jaundice in the Adult Patient Jaundice in an adult patient can be caused by a wide variety of benign or life-threatening disorders. Organizing the differential diagnosis by prehepatic, intrahepatic, and posthepatic causes may help make the work-up more manageable. mark for My Articles similar articles
American Family Physician
September 1, 2006
Cirrhosis and Chronic Liver Failure: What You Should Know The basics about cirrhosis and chronic liver failure. mark for My Articles similar articles
BusinessWeek
November 29, 2004
Carey & Barrett
Lessons From The Vioxx Fiasco What drugmakers, the FDA, doctors, and patients need to do. mark for My Articles similar articles
Bio-IT World
August 13, 2003
Malorye Branca
Targeting Tumors Next-generation cancer drugs will take aim with unprecedented certainty, but making them requires a new discovery and development paradigm. mark for My Articles similar articles
American Family Physician
October 1, 2000
Kelly W. Jones, Pharm.D. & Supen R. Patel, M.D.
A Family Physician's Guide to Monitoring Methotrexate Although the drug is usually prescribed by a subspecialist, a family physician may assume responsibility for monitoring methotrexate therapy... mark for My Articles similar articles
Chemistry World
March 26, 2014
Katia Moskvitch
Nanoparticle sensors detect drug damage in the liver Stanford University researchers have created nanoparticle-based sensors that can image metabolites in animal livers, which they say could help eliminate toxic drug candidates before they are given to humans. mark for My Articles similar articles
Bio-IT World
March 2006
Michael A. Greeley
The Theranostics Promise A huge amount of discovery and clinical development for new drugs involves clinical trials that include companion diagnostic tests. These theranostic tests are poised to become a promising market for entrepreneurs, though challenges -- such as patent issues -- remain. mark for My Articles similar articles
Bio-IT World
September 9, 2002
Malorye Branca
The New, New Pharmacogenomics The field of pharmacogenomics proves valuable in the battle against toxicity and late-stage drug failure -- one of the pharmaceutical industry's biggest problems. mark for My Articles similar articles
The Motley Fool
July 9, 2008
Brian Lawler
Predicting More Good News From Invitrogen Invitrogen gets a positive review from the FDA for one of its tests. mark for My Articles similar articles
Chemistry World
May 18, 2010
Sarah Houlton
EPA and pharma join forces The US Environmental Protection Agency is working with pharmaceutical companies to improve its ToxCast toxicity prediction tool. mark for My Articles similar articles
American Family Physician
March 15, 2004
Management of Hepatitis C: Evaluating Suitability for Drug Therapy Chronic hepatitis C virus infection is a common and serious disease. Although an estimated 2.7 million persons in the United States have this disease, most have not yet been diagnosed. mark for My Articles similar articles
BusinessWeek
June 13, 2005
Catherine Arnst
Biotech, Finally The past 30 years of biological discoveries, insights into the human genome, and exotic chemical manipulation have unleashed a wave of biological drugs, many of them reengineered human proteins. mark for My Articles similar articles
Chemistry World
May 9, 2011
Sarah Houlton
Ecstasy substitute poses major health risks Scientists at Anglia Ruskin University haves shown that one of the most common 'legal high' designer drugs, benzylpiperazine, is not only dangerous when it's taken - repeated consumption poses major health risks. mark for My Articles similar articles
Chemistry World
August 7, 2012
Emma Eley
Improved drugs to treat malarial liver infection Antimalarial drugs with increased in vitro activity have been developed by scientists in Portugal and the US. These novel drugs, called primacins, are active against two stages of malarial infection. mark for My Articles similar articles
Chemistry World
July 15, 2008
Hepeng Jia
Testing Times for New Liver Drug AstraZeneca is set to start clinical trials of a liver cancer drug developed for Chinese patients. mark for My Articles similar articles
The Motley Fool
February 4, 2010
Brian Orelli
Surfing the Wave of the Future: Personalized Medicine Medco buys in to personalized medicine. Yesterday Medco Health Solutions said it's purchasing genetic-testing expert DNA Direct. mark for My Articles similar articles
Bio-IT World
March 8, 2005
Patricia Reilly
Biomarkers: Trends and Potential Companies are centralizing biomarker research to help reduce spending. mark for My Articles similar articles
Nursing
December 2008
Susan Simmons Holcomb
Caring for a patient with chronic hepatitis C Teach your patient about improved treatments that can help him deal with this potentially deadly infection. mark for My Articles similar articles
American Journal of Nursing
October 2009
Pharmacogenomics: Personalizing Drug Therapy Pharmacogenomics is a rapidly growing field of research into the ways in which genetic variation affects drug response. mark for My Articles similar articles
American Family Physician
November 1, 2001
Thomas R. Riley
Preventive Strategies in Chronic Liver Disease Chronic liver disease is the 10th leading cause of death in the United States. Preventive care can significantly reduce the progression of liver disease. Part I: Alcohol, Vaccines, Toxic Medications and Supplements, Diet and Exercise... mark for My Articles similar articles