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Information Today May 3, 2010	EPA Releases New Chemical Toxicity Database This database allows scientists and the interested public to search and download thousands of toxicity testing results on hundreds of chemicals. ToxRefDB captures 30 years and $2 billion of testing results.
Information Today June 20, 2011	EPA Releases Two New Databases With Chemical Toxicity and Exposure Data The U.S. Environmental Protection Agency has announced the release of two databases that make it easier to find data about chemicals.
Chemistry World March 30, 2009 Rebecca Trager	EPA announces new chemical toxicity plan New regulations mean the agency will now rely less on animal testing to assess toxicity and risk, focusing instead on using advanced tools from fields like genomics, molecular biology and computational sciences.
Chemistry World July 24, 2007 Richard Van Noorden	A Viable Alternative Tests on mice, rats, rabbits and guinea pigs to stop harmful chemicals reaching humans were once a necessary evil. But such checks now seem embarrassingly old-fashioned, according to a report on toxicity testing.
Chemistry World December 19, 2011 Rebecca Trager	US agencies collaborate to test 10,000 chemicals A high-speed robotic screening system jointly initiated by three key US health agencies began testing more than 10,000 chemical compounds for potential toxicity on 7 December.
Chemistry World December 8, 2015 Colacci & Kleinstreuer	Rethinking risk assessment For the purposes of regulation, the onset of adverse effects is key to determining the level of exposure that presents an unreasonable risk for humans and ecosystems.
Chemistry World January 16, 2014	The art of alternatives Recent years have seen great advances in alternatives to animal tests. Yet we still need to understand how and why compounds are toxic before we can make the giant leap to replacement.
Chemistry World May 4, 2011 Hepeng Jia	Animal testing alternatives for China 'China can lead the way in applying alternatives to animal testing,' says Melvin Andersen, a professor of toxicology from the Hamner Institute for Health Sciences, North Carolina, in the US, speaking at a Unilever sponsored meeting in Shanghai, on 14 March.
Chemistry World September 7, 2012 Rebecca Trager	EPA urged to rethink chemical risk evaluation process The US Environmental Protection Agency's process for assessing the risk of human exposure to various chemicals is deeply flawed and actually threatens public health, according to two experts with inside experience.
Bio-IT World April 15, 2003 Mark D. Uehling	Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials.
Bio-IT World Jul/Aug 2006 Eric K. Neumann	Combining Drug Toxicity Knowledge Nearly half the drugs entering clinical trials will fail because of some form of serious toxicity that was missed in preclinical studies. These failures should not happen at such a late stage in the process. So what can be done?
Chemistry World February 9, 2015 Rebecca Trager	US on track to phase out most perfluorinated chemicals this year The US Environmental Protection Agency says that the major chemical companies it has partnered with are on track to phase out production of perfluorinated chemicals in America by the end of 2015.
Chemistry World April 27, 2015 Mark Peplow	An unfortunate oversight Transparent and effective third-party oversight is one of the surest ways of securing trust in an industry. Yet in the US, where chemicals are regulated under the Toxic Substances Control Act (TSCA, pronounced 'Tosca'), that oversight is sadly lacking.
Chemistry World November 18, 2015 Emma Davies	Advancing animal testing alternatives The European Chemicals Agency has begun to ask companies to demonstrate that they have carefully considered using alternatives to animal tests.
Chemistry World November 3, 2009 Rebecca Trager	First tests for pesticide endocrine effects in US The EPA has requested that manufacturers screen seven compounds under this first round, including atrazine - a widely used herbicide that may be associated with birth defects and other problems.
Scientific American January 2006	Saving Animals and People Use of animals in testing and in biomedical research continues to be necessary and is ethically preferable to experimenting on humans or forgoing cures that could save human lives, but the development and acceptance of animal substitutes deserve enthusiastic support.
Chemistry World February 4, 2008 Rebecca Trager	EPA Rolls Out Nanomaterials Safety Drive The agency has launched a new voluntary program to glean more information about nanoscale materials in an effort to manage the risks posed by nanotechnology-enabled products.
Chemistry World April 9, 2010 Rebecca Trager	EPA seeks heightened scrutiny for 16 chemicals The US Environmental Protection Agency wants to tighten its oversight of certain chemical substances by adding 16 chemicals to its Toxics Release Inventory list.
Chemistry World July 31, 2013 Daniel Johnson	Animal testing failures put drug trial volunteers in danger The reporting of animal studies is biased, inflating the efficacy of drug candidates and pushing them into the clinic before they are ready.
Chemistry World January 29, 2009 Rebecca Trager	EPA's chemical evaluation process 'high-risk' The US government's 32-year-old law regulating chemical safety needs a complete overhaul, according to Congress' investigative arm
The Motley Fool November 30, 2007 Brian Orelli	Clinical Trial Failures Don't Bother These Companies Contract research organizations, outsourcing companies hired by pharmaceutical and biotech companies to run pre-clinical tests and clinical trials for them, succeed even when drugs fail, and more work may be coming their way.
Chemistry World December 22, 2006 Victoria Gill	Metabolic Profiling Could Improve Animal Experiments Different types of rats respond to drugs in substantially different ways that can be tracked by metabolic analysis, according to scientists who say their finding has major implications for designing animal experiments.
Information Today March 7, 2011	EBSCO Publishing to Release Chemical Hazard Information Library CHIL brings toxicology, pharmacology, occupational and public health, and chemical hazard information to corporations, government agencies, medical facilities, and academic institutions.
Chemistry World September 11, 2013 Emma Stoye	Call to overhaul liver toxicity testing Outdated assays for monitoring liver health could have caused dozens of drug candidates to be wrongly scrapped during development, according to new research.
The Motley Fool May 21, 2010 Brian Orelli	And You Thought Biotech Was High-Risk, High-Reward Large clinical trials make cardiovascular drugs risky, but the rewards are there, too.
Chemistry World June 26, 2015 Rebecca Trager	Chemical reform bill advances in US Congress The US House of Representatives has approved a bipartisan bill to revamp the nearly 40-year-old law that governs America's chemicals policy, known as the Toxic Substances Control Act.
Bio-IT World October 10, 2003 Donna Mendrick	Microarrays That Make Drugs Safe Using DNA chips to discover potential toxicity in new drug compounds -- a key application of toxicogenomics -- can predict adverse effects before they occur, enabling safer clinical trials.
Bio-IT World Dec 2006/Jan 2007 Giacomo Bastianelli	The Future of Predictive Biology Predictive biology, data and the integration of disparate research disciplines are key ingredients for the future of drug discovery research and healthcare.
Chemistry World April 29, 2013 Phillip Broadwith	Appeal reverses ECHA call for animal tests An appeal has overturned the European Chemicals Agency's request for additional animal toxicity testing on the automotive air-conditioning refrigerant 2,3,3,3-tetrafluoropropene (HFO-1234yf).
Chemistry World January 26, 2010 Rebecca Renner	EPA targets chemical confidentiality loopholes The US Environmental Protection Agency is taking a tougher stance on confidentiality claims that allow firms to prevent the names of chemicals identified as potential health risks being made available to the public.
Chemistry World November 2006 Derek Lowe	Opinion: In the Pipeline Is there a way to kill off bad drug candidates before companies invest valuable time and money and in them?
Chemistry World December 1, 2014 Derek Lowe	Progress at the pace of the slowest Chemistry is a means to an end in drug research, not an end in itself, and that can take some getting used to. It's worth thinking about where chemistry fits into the big picture.
Chemistry World March 4, 2008 Rebecca Trager	Controversy Over EPA Removal of Top Toxicologist The US Environmental Protection Agency (EPA) is being accused of caving to pressure from the chemical industry after dismissing Deborah Rice from a scientific review panel following protests from the American Chemistry Council.
Chemistry World April 14, 2011 Sarah Farley	Fish in chips: growing embryos in microfluidic systems Scientists in the Netherlands and the UK have shown for the first time that an animal embryo can develop in a microfluidic environment.
AskMen.com Richard Stevens	Participating In Clinical Trials Check out what participating in clinical trials involves and how you can join a study. You may even make some cash in the process.
Chemistry World May 30, 2013 Rebecca Trager	Industry applauds US chemical reform bill The US chemical industry is backing bipartisan legislation that would reform the law that controls chemical sales in the US for the first time since its enactment in 1976. But environmental groups do not share the enthusiasm.
Chemistry World May 13, 2014 Rebecca Trager	EPA improves embattled chemical assessment program The US Environmental Protection Agency has made 'substantial improvements' to its program to assess the health hazards posed to people by pollution, but the National Research Council is urging further reforms in a new report.
Chemistry World June 23, 2009 Rebecca Trager	EPA halts its chemical review effort The US Environmental Protection Agency is reevaluating its existing chemicals assessment framework and has suspended its Chemical Assessment and Management Program.
Chemistry World April 16, 2010 Rebecca Trager	Congress proposes toxic chemical regulation reforms The US Congress launched a much anticipated effort to update the nation's 34-year-old law governing new and already existing toxic chemicals yesterday.
Chemistry World June 13, 2011 Rebecca Trager	EPA discloses confidential chemical information The US Environmental Protection Agency has made public company data on over 150 chemicals used in more than 100 health and safety studies.
Chemistry World July 26, 2012 Andrew Turley	New US chemical rules edge nearer A political committee in the US has voted in favor of plans to change the way chemicals are regulated by shifting the burden of proving safety to manufacturers.
Chemistry World May 28, 2008 Rebecca Trager	Changes to US chemical review procedures flawed Recent changes to the US Environmental Protection Agency's (EPA) main tool for assessing the health effects of chemicals could significantly lengthen the time needed to review them, a congressional watchdog has warned.
Chemistry World September 25, 2008 Rebecca Trager	EPA suspends two studies on children The US Environmental Protection Agency has canceled funding for two studies during which babies and young children would have been exposed to pesticides and other chemicals because of ethical concerns.
Chemistry World January 2012	Column: In the pipeline Derek Lowe discusses how companies are increasingly trying to do more with the compounds they already know a lot about
The Motley Fool July 20, 2005 Stephen D. Simpson	Pfizer's Long Road Back It took time for Pfizer to reach a trough and it will take time to climb out. But over the long haul this could prove to be a solid pick.
Bio-IT World August 13, 2002 Mark D. Uehling	Clinical Trial Data Management: Tortured by Paper Reams of paper stuffed into boxes and shipped to the FDA by the truckload is hardly the best approach to drug approval. But what's the right way?
Chemistry World January 11, 2010 Helen Carmichael	EPA: Bankrupt chemical firms must pay for site clean up The US Environmental Protection Agency has tabled new proposals to prevent taxpayers footing the environmental clean up bills for cash-strapped chemical companies.
Chemistry World October 1, 2008 Rebecca Trager	US to Overhaul Industrial Chemicals Inventory A plan by the US Environmental Protection Agency to overhaul its inventory of industrial chemicals could lead to a lot more paperwork for chemical firms, industry officials have warned.
Chemistry World May 24, 2012 Rebecca Trager	EPA's chemical assessment program The US National Academy of Sciences will conduct a 'comprehensive examination' of the assessment process that underlies the EPA's Integrated Risk Information System, through which the agency provides health data on over 550 chemical substances.
Chemistry World April 9, 2015	Big problems with little particles? There is a risk that poor toxicology studies could start undermining the success of nanomaterials.