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Chemistry World January 16, 2014	The art of alternatives Recent years have seen great advances in alternatives to animal tests. Yet we still need to understand how and why compounds are toxic before we can make the giant leap to replacement.
Chemistry World May 4, 2011 Hepeng Jia	Animal testing alternatives for China 'China can lead the way in applying alternatives to animal testing,' says Melvin Andersen, a professor of toxicology from the Hamner Institute for Health Sciences, North Carolina, in the US, speaking at a Unilever sponsored meeting in Shanghai, on 14 March.
Chemistry World November 18, 2015 Emma Davies	Advancing animal testing alternatives The European Chemicals Agency has begun to ask companies to demonstrate that they have carefully considered using alternatives to animal tests.
Chemistry World August 27, 2009 Sarah Houlton	Reach costs set to spiral The EU's Reach chemicals legislation could use 20 times more animals and cost six times more than originally estimated, according to two toxicologists.
Chemistry World May 18, 2010 Sarah Houlton	EPA and pharma join forces The US Environmental Protection Agency is working with pharmaceutical companies to improve its ToxCast toxicity prediction tool.
Chemistry World June 6, 2014 Phillip Broadwith	Data sharing helps firms reduce Reach animal testing Companies sharing safety data and developing test protocols has helped reduce the need for animal testing required by the European regulations.
Chemistry World March 30, 2009 Rebecca Trager	EPA announces new chemical toxicity plan New regulations mean the agency will now rely less on animal testing to assess toxicity and risk, focusing instead on using advanced tools from fields like genomics, molecular biology and computational sciences.
Chemistry World April 15, 2013	BASF introduces cell-based allergen test German chemicals giant BASF has announced a new in vitro, cell-based test for allergenic substances. The method aims to replace animal tests for skin sensitizing action of new chemicals.
Chemistry World May 28, 2008 Arthur Rogers	EU strikes deal on Reach toxicity tests Under pressure from Members of the European Parliament, the European Commission has promised to speed up validation and authorization of toxicity tests that avoid the use of animals.
Scientific American January 2006	Saving Animals and People Use of animals in testing and in biomedical research continues to be necessary and is ethically preferable to experimenting on humans or forgoing cures that could save human lives, but the development and acceptance of animal substitutes deserve enthusiastic support.
Chemistry World December 24, 2014 Phillip Broadwith	EU chemicals regulator scolded over animal testing The European Ombudsman has upheld a complaint made by animal rights group PETA that the European Chemicals Agency is not doing enough to enforce substitution of animal testing.
Pharmaceutical Executive December 1, 2008 Sarah Houlton	Animal Humanity The new EU directive looks to reduce, refine, and eventually replace animal testing.
Information Today May 3, 2010	EPA Releases New Chemical Toxicity Database This database allows scientists and the interested public to search and download thousands of toxicity testing results on hundreds of chemicals. ToxRefDB captures 30 years and $2 billion of testing results.
Chemistry World December 19, 2011 Rebecca Trager	US agencies collaborate to test 10,000 chemicals A high-speed robotic screening system jointly initiated by three key US health agencies began testing more than 10,000 chemical compounds for potential toxicity on 7 December.
Chemistry World June 5, 2014 Dominic Williams	Chemical toxicity prediction The book is written in such a clear way that it is easily understandable by scientists from different fields, which will ultimately contribute to the success of this emerging discipline.
Chemistry World December 8, 2015 Colacci & Kleinstreuer	Rethinking risk assessment For the purposes of regulation, the onset of adverse effects is key to determining the level of exposure that presents an unreasonable risk for humans and ecosystems.
Information Today June 20, 2011	EPA Releases Two New Databases With Chemical Toxicity and Exposure Data The U.S. Environmental Protection Agency has announced the release of two databases that make it easier to find data about chemicals.
Bio-IT World October 10, 2003 Donna Mendrick	Microarrays That Make Drugs Safe Using DNA chips to discover potential toxicity in new drug compounds -- a key application of toxicogenomics -- can predict adverse effects before they occur, enabling safer clinical trials.
Chemistry World December 6, 2012 Elinor Hughes	Stopping endocrine disruptors in their tracks US scientists have come up with a system to assess whether chemists' latest synthetic product is an endocrine disruptor -- a chemical that interferes with hormone regulation in animals and humans.
Chemistry World April 9, 2015	Big problems with little particles? There is a risk that poor toxicology studies could start undermining the success of nanomaterials.
Chemistry World April 27, 2015 Mark Peplow	An unfortunate oversight Transparent and effective third-party oversight is one of the surest ways of securing trust in an industry. Yet in the US, where chemicals are regulated under the Toxic Substances Control Act (TSCA, pronounced 'Tosca'), that oversight is sadly lacking.
Bio-IT World April 15, 2003 Mark D. Uehling	Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials.
Bio-IT World Jul/Aug 2006 Eric K. Neumann	Combining Drug Toxicity Knowledge Nearly half the drugs entering clinical trials will fail because of some form of serious toxicity that was missed in preclinical studies. These failures should not happen at such a late stage in the process. So what can be done?
Chemistry World April 29, 2013 Phillip Broadwith	Appeal reverses ECHA call for animal tests An appeal has overturned the European Chemicals Agency's request for additional animal toxicity testing on the automotive air-conditioning refrigerant 2,3,3,3-tetrafluoropropene (HFO-1234yf).
Chemistry World September 11, 2013 Emma Stoye	Call to overhaul liver toxicity testing Outdated assays for monitoring liver health could have caused dozens of drug candidates to be wrongly scrapped during development, according to new research.
Chemistry World January 12, 2010 Sarah Houlton	EU to look into chemical mixture exposure The Council of the EU has called on the European Commission to look at whether current legislation adequately assesses the risks from exposure to multiple chemicals from different sources.
Pharmaceutical Executive March 1, 2006 Sarah Houlton	Global Report: Chemicals Legislation in Europe Chemicals legislation in Europe may affect pharma's relationship with suppliers.
Bio-IT World December 15, 2003 Malorye A. Branca	Scenes from a Cell Breakthroughs are making cell-based screening faster, easier, more powerful.
The Motley Fool November 28, 2007 Brian Orelli	Stem Your Expectations of Stem-Cell Discoveries Making "stem" cells out of skin cells isn't all it's cracked up to be. The recent discovery has a long way to go before it can catch up to the research currently being done with stem cells.
Chemistry World December 22, 2006 Victoria Gill	Metabolic Profiling Could Improve Animal Experiments Different types of rats respond to drugs in substantially different ways that can be tracked by metabolic analysis, according to scientists who say their finding has major implications for designing animal experiments.
Chemistry World December 2, 2010 James Urquhart	Micro organ system to test cancer drugs Japanese researchers have created an organ-on-a-chip system that simultaneously tests how liver, intestine and breast cancer cells respond to cancer drugs.
Chemistry World June 13, 2014 Ned Stafford	European chemical regulations failing consumers A leading consumer group says chemicals regulations in Europe are inadequate and fail to protect consumers from the risks posed by a broad range of products.
Chemistry World November 2009 Derek Lowe	Column: In the pipeline The author advises opening your mind during the screening cascade taken by potential drug targets, and remaining goal orientated at all times
Bio-IT World February 10, 2003 Malorye Branca	Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic.
Reason October 2000 Frederick K. Goodwin & Adrian R. Morrison	Science and Self-Doubt Why animal researchers must remember that human beings are special...
Chemistry World July 26, 2012 Andrew Turley	New US chemical rules edge nearer A political committee in the US has voted in favor of plans to change the way chemicals are regulated by shifting the burden of proving safety to manufacturers.
Chemistry World August 8, 2010 James Urquhart	No nanotube fertility risk US and Chinese researchers have found that carbon nanotubes injected into male mice cause damage to the testes, but the harm is reversible and does not affect fertility.
Mother Jones August 1999 Jon R. Luoma	System Failure The chemical revolution has ushered in a world of changes. Many of them, it's becoming clear are in our bodies
Information Today March 7, 2011	EBSCO Publishing to Release Chemical Hazard Information Library CHIL brings toxicology, pharmacology, occupational and public health, and chemical hazard information to corporations, government agencies, medical facilities, and academic institutions.
Bio-IT World Dec 2006/Jan 2007 Giacomo Bastianelli	The Future of Predictive Biology Predictive biology, data and the integration of disparate research disciplines are key ingredients for the future of drug discovery research and healthcare.
Chemistry World September 29, 2006 Simon Hadlington	WWF Study Slammed by Scientists As the long-running saga to get a new regulatory framework for the chemical industry onto the European statute book enters another key chapter, a frenzy of lobbying is underway.
Chemistry World July 8, 2015 Ida Emilie Steinmark	Phthalate replacements linked to child health problems Supposedly safe replacements for a harmful plasticiser have been found to positively correlate with both increased blood pressure and insulin resistance in children and adolescents.
Chemistry World December 18, 2012 Jennifer Newton	Technique to measure chemotherapy effectiveness A technique to measure how effective chemotherapy is by studying the physical changes that occur in human cells has been developed by US scientists.
Chemistry World February 6, 2013 Andrew Turley	Reach reviewed: no change required Chemical regulation in the EU is working as it should be, although there is room for improvement in its implementation, according to a long-awaited review from the European commission.
Bio-IT World August 18, 2004 John Russell	Curbing a Killer Iconix Pharmaceuticals is working on building biomarkers that can predict toxicity and efficacy.
Chemistry World April 14, 2011 Sarah Farley	Fish in chips: growing embryos in microfluidic systems Scientists in the Netherlands and the UK have shown for the first time that an animal embryo can develop in a microfluidic environment.
Chemistry World September 10, 2014 Patrick Walter	Growth slow for European chemicals in 2014 The European chemicals sector has seen only sluggish growth in the first half of 2014, according to the latest European Chemical Industry Council report.
Chemistry World March 11, 2015 Ned Stafford	State of Europe's environment scrutinized The European Environment Agency says progress has been made toward cleaning Europe's air and water and reducing waste disposal, but that major environmental challenges remain.
Science News March 25, 2006 Janet Raloff	Meat Poses Exaggerated Cancer Risk for Some People The National Toxicology Program confirmed that heterocyclic amines that form in overcooked meat can trigger colon cancer in animals and probably do the same in people.
Chemistry World December 7, 2009 Leila Sattary	Cold reception for new EU chemical security drive New European Union counter-terrorist measures could duplicate existing security procedures and increase administrative burden on the chemical sector, say industry representatives.