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Chemistry World July 17, 2012 Harriet Brewerton	Pinning down cancer US scientists have synthesized pin-shaped nanoparticles with magnetic and optical properties. The nanoparticles could be used for magnetic resonance imaging, early detection and photothermal therapy of cancer and other diseases.
Chemistry World March 21, 2010 Simon Hadlington	Nanoparticles successfully deliver RNA interference in cancer patients The system aims to exploit the phenomenon of RNA interference, where short sequences of double-stranded RNA, called small interfering RNA or siRNA, can trigger the disruption of the manufacture of certain proteins in a cell.
Chemistry World February 4, 2011 Harriet Brewerton	Transplant tracking Magnetic nanoparticles could be used to track neural stem cells after a transplant in order to monitor how the cells heal spinal injuries, say UK scientists.
Chemistry World November 27, 2007 James Mitchell Crow	A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells.
Chemistry World April 11, 2006 Jon Evans	Nanotechnology Tackles Chemotherapy Chemists and medical researchers have developed nanoparticles that target chemotherapy drugs directly at tumours. The researchers claim that the same technique could be used to develop nanoparticle-based treatments for a wide range of other diseases.
Chemistry World February 13, 2006	Nanoparticles Detect Cell Suicide Plans Researchers have developed a nanotechnological assay for detecting programmed cell death. The technique is effective in cell cultures, they report, and might eventually be used in humans.
Chemistry World October 7, 2012 David Bradley	Magnetic nanoparticles zap cancer Nanoparticles can be used as a remote-controlled magnetic death switch to kill cancer cells, according to researchers from Korea.
Chemistry World March 16, 2009 Hayley Birch	Nanodumbbells Target Cancer Cells US scientists have designed nanoparticles that function like 'guided missiles' in the targeted destruction of breast cancer cells.
Chemistry World July 31, 2012 Fiona McKenzie	Sorting the good from the bad US scientists have found a way to separate cancerous cells from healthy cells by taking advantage of their adhesion properties. Separating cancer cells for analysis is a critical step for determining the recommended course of treatment for patients.
Chemistry World February 11, 2013 Helen Potter	A new system for cancer detection Cancer cells have been found to differ from normal cells in several ways, including the make up of their cell membranes. Cancer-cell membranes have been found to contain more anionic lipids than normal cells, leading to an overall negatively charged cell surface.
Chemistry World October 2, 2012 Fiona McKenzie	Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells.
Chemistry World June 9, 2008 Simon Hadlington	Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes.
Chemistry World February 14, 2011 Rachel Cooper	Small and sensitive nanoparticles A new highly sensitive nanoparticle contrast agent for imaging in the body stays in the bloodstream longer and is better at targeting tumors than other nanoparticle contrast agents, say Chinese scientists.
Chemistry World January 17, 2011 Laura Howes	Nanoparticle divides to conquer Scientists have made a nanoparticle that breaks up into smaller units once it reaches its target, allowing it to penetrate deeper into tumour tissue and deliver treatment more effectively.
Chemistry World April 5, 2007 Lionel Milgrom	Nanoparticles Make Better MRI Images Manganese oxide nanoparticles have been used as contrast agent for magnetic resonance imaging, allowing researchers to see inside living brains in the same detail as dissected tissue under a microscope.
Chemistry World January 2, 2015 Thadchajini Retneswaran	Smart nanoparticles take aim at cancer cells Scientists in China have developed an intelligent nanoparticle system that delivers a chemotherapeutic and radiosensitizer drug directly to the nucleus of cancer cells.
Chemistry World April 28, 2008 Victoria Gill	Gene silencing gets fat A team of researchers in the US has developed fat-like nanoparticles that can carry fragments of RNA into cells, bring treatments based on gene silencing a step closer.
Chemistry World June 14, 2007 James Mitchell Crow	Young-Ish Giants Party On Chemist Fraser Stoddart celebrated his 65th birthday in scholarly style last week, with a group of chemistry's rising stars that raised a glass - and a slide or two - in his honor.
Chemistry World February 12, 2014 Manisha Lalloo	Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer.
Chemistry World March 6, 2006 Jon Evans	Nanoprobes Light up Cellular Demolition Researchers have developed a method for detecting and imaging programmed cell death (apoptosis). The method, involving polymer nanoparticles, could be used to diagnose apoptosis-related diseases and inform drug development.
Chemistry World September 25, 2009 Simon Hadlington	New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging.
Chemistry World March 20, 2009 Jon Cartwright	Medical Probes Get Easy to Spot Scientists in the US have created nano-scale medical probes that are visible via both magnetic resonance imaging (MRI) and optical microscopy.
Chemistry World September 26, 2006 Fiona Case	Synchronised Delivery for DNA and Drugs Polymer capsules that can simultaneously deliver drug molecules and DNA into a cell could boost the power of cancer treatments.
Chemistry World January 20, 2011 Hayley Birch	Programmable RNA promising for bio-compatible therapies Programmable nanostructures based on ribonucleic acid could be used as vessels for shipping therapeutic molecules into cells, according to US scientists.
Chemistry World June 27, 2010 Simon Hadlington	Nanoparticles allow remote control of cells In an experiment reminiscent of the mind-control rays that featured prominently in B-movies from the 1950s, scientists in the US have used a magnetic field to alter the behavior of an animal.
Chemistry World March 21, 2014 Richard Massey	Magnetic field and pH synergy controls therapeutic burst Australian researchers have shown how alternating magnetic fields could be used to localize the release of cancer-fighting drugs to cancer cells, limiting side effects in the rest of the body.
Chemistry World April 7, 2009 Lewis Brindley	Cells get in line Magnetic nanoparticles that 'shepherd' cells into neat lines have been designed by American scientists.
Chemistry World July 25, 2013 Rowan Frame	Nanomagnets clean blood Nanoparticles that never have to enter the body can capture harmful components in blood, scientists in Switzerland have shown.
Chemistry World January 25, 2010 Hayley Birch	Stabilising RNAs enhances gene silencing in tumours South Korean scientists have found a way to stabilise therapeutic RNA molecules, using chemical modifications, so that they can be more smoothly trafficked into cells.
HHMI Bulletin Aug 2011 Richard Saltus	T-Cell Booster Kits A bioengineer remodels cell surfaces to prod the immune system.
Chemistry World September 23, 2008 Simon Hadlington	Nanoparticles Hide Behind Protein Cloak Polymer nanoparticles suspended in human blood become cloaked in plasma proteins, new research has shown.
Chemistry World March 21, 2013 Phillip Broadwith	AstraZeneca partners with Moderna for $240 million Moderna has developed a way to use messenger RNA (mRNA), the molecule cells use to turn DNA into proteins, to stimulate the production of specific proteins in cells where disease has diminished or eliminated their ability to do so.
Chemistry World June 12, 2012 Nina Notman	Three pronged approach puts brakes on US breast cancer The US Food and Drug Administration (FDA) has approved the use of anti-HER2 therapy Perjeta (pertuzumab) to treat patients with previously untreated HER2-positive metastatic breast cancer.
Chemistry World July 28, 2009 Michael Gross	DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise.
Chemistry World October 19, 2015 Laura Fisher	Prostate cancer detection comes of phage Researchers in the US have wrapped bacteriophage with the polymer PEG (polyethylene glycol) to make a structure that detects PSMA, a molecular flag for prostate cancer.
Chemistry World January 31, 2008 John Bonner	RNAi Scores Victory Against Crohn's Disease in Mice Thousands of people suffering from the debilitating gut condition Crohn's disease could experience relief from their symptoms through a technique that blocks production of a key protein in the inflammation process.
Chemistry World November 21, 2006 Victoria Gill	Side-Effect-Free Chemotherapy Scientists have now developed an enzyme with the potential to eliminate the extreme fatigue, sickness and hair loss that result from this cell damage and strike fear into the hearts of cancer patients.
Chemistry World August 7, 2008 Simon Hadlington	RNA stops HIV in its tracks Scientists have successfully used a biochemical Trojan horse to smuggle killer sequences of RNA into immune cells to mug invading HIV, stopping infection in its tracks
Chemistry World November 25, 2011 Jon Evans	Cancer diagnosis goes for gold Gold nanoparticles could help diagnose a wide range of different cancers by detecting telomerase activity within cells, say Chinese chemists.
Chemistry World November 15, 2011 Phillip Broadwith	Creating a toolbox for nanoparticle synthesis Hybrid nanoparticles made from several different materials that can be built up in a controlled and directed manner have been created by chemists in the US.
Chemistry World February 12, 2012 Jon Cartwright	Nanoparticles slow iron absorption in the gut Nanoparticles used in food and pharmaceuticals could have unintended physiological effects.
Chemistry World January 26, 2011 Anna Watson	Channelling deeper to target breast cancer US scientists have developed a model of the breast ductal system that could be used to discover abnormal cells or deliver drugs at locations further along the ducts than other techniques. The model fits on a slide, enabling on-chip experiments.
Managed Care November 2003 Thomas Morrow	Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings.
Chemistry World January 13, 2010 Simon Hadlington	Click chemistry reveals sugar synthesis in live animals US researchers have used 'click chemistry' to attach chemical tags to complex sugar molecules in the cells of live mice, allowing the synthesis of the sugars - glycans - within the cells to be tracked.
Chemistry World June 12, 2013 Sarah Houlton	No small success Chad Mirkin has been the driving force behind four spin-out nanotechnology companies, and has more than 850 patents to his name. Yet he describes himself as something of an accidental chemist. He is particularly proud of spherical nucleic acids.
AskMen.com Jacob Franek	New Cancer Therapies As cancer research explodes, the availability of new and innovative interventions is expanding almost daily.
Chemistry World July 30, 2007 James Mitchell Crow	Cell Transplant Hope for Diabetes Sufferers Iron-based 'magnetocapsules' of insulin-producing cells could help doctors use cell transplants to treat type I diabetes.
Chemistry World July 22, 2013 Kirsty Muirhead	Circulating cancer cells spiral towards separation A new biochip developed by researchers in Singapore can isolate tumor cells from blood samples, and may one day be an alternative to more invasive methods for tracking later stage cancers.
Reactive Reports Issue 56 Jeffrey Krise	A Basic Approach to Chemotherapy Chemists have found a way to attack malignant cells with an anticancer drug, while sparing healthy cells.
Chemistry World October 20, 2008 Hayley Birch	RNA computers built in yeast US scientists have assembled ribonucleic acids into an adaptable logic system that can be programmed to sense and respond to molecules inside living yeast cells.