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Chemistry World May 30, 2008 Michael Gross |
Improving photodynamic cancer therapy Chemists in the UK and Canada have developed a new molecule that can help doctors to destroy cancer cells with unprecedented precision, using a technique known as photodynamic therapy (PDT). |
Chemistry World November 27, 2007 James Mitchell Crow |
A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells. |
Chemistry World June 12, 2013 Sarah Houlton |
No small success Chad Mirkin has been the driving force behind four spin-out nanotechnology companies, and has more than 850 patents to his name. Yet he describes himself as something of an accidental chemist. He is particularly proud of spherical nucleic acids. |
Chemistry World May 13, 2009 Lewis Brindley |
Combination nanoparticles to fight cancer Korean chemists have assembled a multitalented nanoparticle that can hunt down, treat, and illuminate cancerous cells. |
Chemistry World September 27, 2006 Victoria Gill |
Printing Nano Portraits Making 55,000 nanoscale images of Thomas Jefferson might sound like an eccentric art project, but this is the first demonstration of a new technique that harnesses the power of thousands of nanoscale pens working in synchrony. |
Chemistry World January 17, 2008 Lewis Brindley |
Nanomachines to Treat Cancer Scientists at the University of California-Los Angeles (UCLA) have signed a deal with a private investment firm to develop and market 'nanomachines' to treat cancer. |
Chemistry World July 10, 2007 Tom Westgate |
Attosyringe Shows Potential Electrochemists have given hope to biologists who want to inject precise and tiny volumes of fluids into living cells. They have developed a syringe that delivers attolitre volumes. |
Chemistry World January 31, 2008 John Bonner |
RNAi Scores Victory Against Crohn's Disease in Mice Thousands of people suffering from the debilitating gut condition Crohn's disease could experience relief from their symptoms through a technique that blocks production of a key protein in the inflammation process. |
Chemistry World March 21, 2010 Simon Hadlington |
Nanoparticles successfully deliver RNA interference in cancer patients The system aims to exploit the phenomenon of RNA interference, where short sequences of double-stranded RNA, called small interfering RNA or siRNA, can trigger the disruption of the manufacture of certain proteins in a cell. |
Chemistry World May 24, 2013 Jennifer Newton |
Releasing reactive oxygen Scientists in Canada have made nanoparticles that release singlet oxygen when a laser beam is shone on them. The nanoparticles could improve the effectiveness of photodynamic therapy, a treatment for some cancers. |
Chemistry World August 22, 2011 Jon Cartwright |
Manmade molecular machine goes to work Manmade molecules can generate similar forces to natural molecular machines, and could help chemists to design artificial molecular machines for meaningful tasks. |
Chemistry World October 7, 2010 Simon Hadlington |
New light shed on 'photothermal' cell death Photothermal therapy - where tiny particles of a metal are introduced into a cell and heated by laser light to kill the cell - might not work in the way people think, researchers in the UK have discovered. |
Chemistry World July 28, 2009 Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
Chemistry World January 4, 2007 Richard Van Noorden |
Knighthood for Services to Chemistry Fraser Stoddart, director of the California NanoSystems Institute and professor of NanoSystems Sciences at the University of California, has been appointed a Knight Bachelor for his services to chemistry and molecular nanotechnology. |
Chemistry World January 11, 2008 John Bonner |
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. |
Chemistry World February 12, 2014 Manisha Lalloo |
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. |
Chemistry World January 19, 2009 Manisha Lalloo |
Synthetic HDL could boost body's 'good cholesterol' US scientists say gold nanoparticle based therapies could be used to help boost levels of good cholesterol in our bodies. |
HHMI Bulletin Nov 2011 Sarah C. P. Williams |
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. |
Chemistry World December 5, 2007 Ananyo Bhattacharya |
Structural Snapshot Shows Monster Protein A structural snapshot of a protein capsule has revealed details of the largest cellular component ever imaged by x-ray crystallography. |
Chemistry World May 24, 2013 Emma Stoye |
Chad Mirkin named Chemistry World Entrepreneur of the Year In particular, the award recognises Mirkin's development and successful commercialization of spherical nucleic acids. He has more than 900 patents to his name and has founded four spin-out companies. |
Chemistry World January 2010 Philip Ball |
Welcome to the machine Molecular machines have promised so much but are they more whimsical than technical? |
Chemistry World April 28, 2008 Victoria Gill |
Gene silencing gets fat A team of researchers in the US has developed fat-like nanoparticles that can carry fragments of RNA into cells, bring treatments based on gene silencing a step closer. |
Chemistry World January 30, 2008 Jonathan Edwards |
DNA Helps Nanoparticles Crystallize Two papers in Nature have each shown a simple way to build designer crystals from nanoparticles, using DNA as 'glue'. Both methods show promise as a cheap way of mass-producing complex materials like photonic crystals. |
Chemistry World May 12, 2014 David Bradley |
Elemental discoveries at the cellular level A combination of two high-power analytical techniques -- synchrotron radiation microscopy and atomic force microscopy -- has allowed Italy scientists to map vital elements in a single cancer cell. |
Chemistry World August 2010 |
Let's get physical The field of physical chemistry is booming, as more and more scientists seek to understand their work on a molecular level |
Chemistry World September 2, 2009 Matt Wilkinson |
Mechanised nanocapsules target drug delivery US researchers have developed a nano-sized drug delivery system that only releases its payload in specific pH conditions, a feature that could prove particularly useful for targeted delivery of cancer treatments. |
HHMI Bulletin Aug 2011 Richard Saltus |
T-Cell Booster Kits A bioengineer remodels cell surfaces to prod the immune system. |
Bio-IT World March 17, 2004 |
Nano-Writing with Bio-Inks Nanolithography comes to bioarrays. |
Chemistry World July 5, 2013 Philip Ball |
A self-assembled periodic table Efforts to rationalize other aspects of chemistry into periodic table analogues come with a degree of baggage. |
HHMI Bulletin Winter 2013 Amber Dance |
A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery. |
Chemistry World March 16, 2009 Hayley Birch |
Nanodumbbells Target Cancer Cells US scientists have designed nanoparticles that function like 'guided missiles' in the targeted destruction of breast cancer cells. |
Smithsonian March 2004 |
Signal Discovery? A Los Angeles scientist says living cells may make distinct sounds, which might someday help doctors "hear" diseases |
Chemistry World October 31, 2012 Ian Le Guillou |
A cell for a cell If you ever need to isolate a single bacterial cell, why not build it a prison cell? This is the approach that colleagues from Sandia National Laboratories, US, have taken. Using multi-photon lithography, they can construct four walls and a roof around a single cell in just over a minute. |
Chemistry World February 9, 2012 Laura Howes |
Polyrotaxanes zip themselves up Received wisdom tells us that taking 39 chemical components and assembling them into one molecule will only be possible with low yields thanks to entropy. But scientists have managed this with yields of 90%. |
Chemistry World February 6, 2008 Simon Hadlington |
Better Detection of DNA Synthesis Researchers in the US have developed a new way to detect DNA synthesis in living cells by using click chemistry -- the concept of reacting together two 'high energy' molecules that 'click' together efficiently under mild conditions. |
Chemistry World February 28, 2013 Andy Extance |
Chemical transport defines 'Goldilocks' cell size A US team has suggested molecular movement as an answer to the question of why cells are the size they are. A question that they say 'still awaits an answer from first principles'. |
HHMI Bulletin May 2010 Robert Tjian |
Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens. |
Chemistry World June 13, 2011 Laura Howes |
Cells turned into living lasers with fluorescent protein With a little help from a fluorescent protein, mammalian cells have been transformed into living lasers. This discovery could help improve imaging of living cells, enabling researchers to explore what's going on inside. |
Chemistry World October 8, 2008 Sarah Houlton |
Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures. |
Managed Care November 2003 Thomas Morrow |
Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings. |
Chemistry World October 20, 2009 James Urquhart |
Gold nanoparticles give super sensitive cancer test The recurrence of prostate cancer could soon be spotted years earlier thanks to a new highly sensitive test developed by US and Austrian researchers. |
Chemistry World April 7, 2009 Lewis Brindley |
Cells get in line Magnetic nanoparticles that 'shepherd' cells into neat lines have been designed by American scientists. |
Reactive Reports Issue 33 David Bradley |
The Miniature Rotarians Tiny interlocking wheels are the components of a miniscule molecular rotor designed and built by UK chemists. The submicroscopic invention offers a new motor-like component for those hoping to build nanotechnology from the bottom up. |
Chemistry World January 10, 2013 Laura Howes |
Rotaxane mimics ribosome to spin out peptides The field of molecular machines has taken a new bio-inspired turn to assemble another molecule, in this case linking up individual amino acids into a peptide. |
Chemistry World March 9, 2009 Lewis Brindley |
Finding the Risks of Nanoparticle Exposure A new model for nanoparticle exposure should provide more realistic insights into the possible health risks of airborne nanoparticles, researchers in Switzerland claim. |
Chemistry World July 6, 2012 |
Protein power Tom Muir, professor of chemistry and molecular biology, Princeton University, US, is an expert in protein engineering and its application to studying cellular signalling networks. |
Chemistry World March 9, 2007 Michael Gross |
Nanowires go Round the Bend Chemists have bent an apparently linear molecular wire into a closed circle, creating a conducting ring just 3 nanometers across. |
Chemistry World July 31, 2012 Fiona McKenzie |
Sorting the good from the bad US scientists have found a way to separate cancerous cells from healthy cells by taking advantage of their adhesion properties. Separating cancer cells for analysis is a critical step for determining the recommended course of treatment for patients. |
Chemistry World April 2, 2007 Simon Hadlington |
Nucleic Acid Aids Clotting Researchers say they may have solved one of biochemistry's bloodier conundrums - the physiological reason why blood coagulates in the presence of 'foreign' surfaces such as glass. |
Chemistry World February 2012 |
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball |