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Chemistry World January 8, 2014 Karl Collins |
Oxidation station Small molecules are making significant inroads -- with reactivity and selectivity approaching levels previously thought unachievable. |
Chemistry World March 14, 2014 Simon Hadlington |
Chemists make headway on C--H activation challenges Jin-Quan Yu's group at the Scripps Research Institute at La Jolla, California, have synthesized a library of synthetic chiral amino acids which could have applications in the pharmaceutical industry. |
Chemistry World July 15, 2010 Simon Hadlington |
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. |
Chemistry World December 21, 2012 Laura Howes |
Engineered enzyme performs cyclopropanation by carbene transfer While biomimetic chemistry has been busy learning from nature, other chemists have been busy modifying enzymes to develop biocatalysts for other reactions. |
Chemistry World September 13, 2012 Ian Le guillou |
Fluorination via porphyrin A manganese porphyrin has been used to selectively fluorinate sp 3 carbon -- hydrogen bonds using silver fluoride as a source of fluorine. |
Chemistry World March 6, 2008 Simon Hadlington |
Synthetic Enzymes Designed by Computer Scientists in the US have designed and built an artificial enzyme from scratch. |
Chemistry World March 20, 2007 Lionel Milgrom |
Chemical Model Unlocks Key Enzyme's Secrets The precise workings of cytochrome c oxidase (CcO), an enzyme that is crucial for all aerobic life, have been unveiled. |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World February 24, 2011 James Urquhart |
Elusive form of iron captured Researchers in the US and Germany have synthesised and characterised an iron nitride compound that reacts with water to produce high yields of ammonia under mild conditions. |
Chemistry World November 27, 2013 Jennifer Newton |
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. |
Chemistry World February 25, 2014 Simon Hadlington |
Synthetic 'textbook model' of a biological catalyst Scientists have developed a simple two-molecule chemical analogue of an enzyme and its substrate that neatly illustrates the fundamental principles of biological catalysis. |
Food Processing August 2007 Mark Anthony |
Nutrition Beyond the Trends: Connecting the Dots on Enzymes Lactase -- an enzyme that splits lactose into its constituent sugars, glucose and galactose -- can make short work of the lactose intolerance problem. |
Chemistry World November 26, 2012 Laura Howes |
Protein coat prepares catalyst for cascades By protecting a transition metal catalyst with a protein coat, scientists have managed to couple up biocatalysts and chemical catalysts to perform a cascade reaction. |
Chemistry World April 14, 2006 Simon Hadlington |
Deciphering Hydrogen Tunnelling in Enzymes Researchers have thrown important new light on the phenomenon of hydrogen tunnelling in biological catalysts. The finding is likely to spark a debate among biochemists about the fundamental nature of enzymes. |
Chemistry World March 16, 2015 Elisabeth Ratcliffe |
Enzyme selectivity switch to benefit infant formula production Scientists in Austria who have redesigned the active site of an enzyme to switch its regioselectivity may have latched onto a new way to make molecules that are important for infant formula. |
Chemistry World January 6, 2010 Phillip Broadwith |
Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain. |
Chemistry World November 27, 2011 James Mitchell Crow |
Artificial enzymes close in on nature A synthetic metalloprotein that approaches the catalytic performance of a natural enzyme, despite its stripped-down structure, has been developed by a team of chemists in the US. |
Chemistry World March 4, 2011 Carl Saxton |
Real-world treatment for dye-contaminated effluents US scientists have found that a dye oxidation process using low levels of an iron catalyst could be used to degrade highly contaminated wastewater under ambient conditions. |
Chemistry World December 12, 2006 Michael Gross |
Ancient Protein Moonlights in the Eye A structural protein in the mouse eye lens is the evolutionary descendant of an ancient bacterial enzyme, researchers have found -- suggesting that moonlighting saved the protein from oblivion when its original role was taken over by a different family of enzymes. |
Chemistry World October 1, 2015 Matthew Gunther |
Excess protons play hopscotch in water Scientists in the US have observed how excess protons move through water. |
Chemistry World November 12, 2007 Simon Hadlington |
Coupled Enzymes May Spawn New Catalysts Chemists at the University of Oxford have created a new type of catalyst by attaching two enzymes to a microscopic flake of graphite. The system could be tailored to catalyze a range of reactions, the researchers say. |
Chemistry World December 9, 2013 Jessica Cocker |
Hydrogen breaks strong bonds with brute force A method developed by Leo Lau of Western University in Canada and colleagues can break C -- H bonds without damaging the rest of the molecule. |
Chemistry World September 3, 2008 Lewis Brindley |
Hydroxide argument settled Scientists in Germany say they have settled an argument over how hydroxide ions travel quite so quickly through water, after finding evidence that they can donate a weak hydrogen bond. |
Chemistry World July 25, 2008 Simon Hadlington |
Structure of hydrogen splitting enzyme revealed Scientists in Germany have brought the prospect of generating cheap electricity from hydrogen a step closer by taking a snapshot of an elusive enzyme that can split the gas as efficiently as a platinum catalyst. |
Prepared Foods February 2008 Sharon Book |
Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage. |
Chemistry World November 3, 2015 Matthew Gunther |
IR spectroscopy stretches knowledge of hydrogen bonding Scientists in Denmark have, for the first time, detected a hydrogen bond between an N -- H and phosphorus in the gas phase. |
Chemistry World January 17, 2014 Phillip Broadwith |
Plug and play redox enzymes With the constant drive to make chemical synthesis ever cleaner, more energy-efficient and generate less waste -- both in research and industrial processes -- more and more chemists are looking to harness enzyme catalysis. |
Chemistry World September 21, 2009 Hayley Birch |
Enzymes inspire new catalyst design for hydrogen production A novel enzyme-based catalyst developed by UK and US researchers hints at new ways of designing catalysts for the water-gas shift reaction, an important industrial reaction in the production of high grade hydrogen. |
Chemistry World October 31, 2013 Derek Lowe |
Natural born chemists Organic chemists may not seem like a humble group. But we should be, because we are humiliated every hour of the day by what nature accomplishes through enzyme catalysis. |
Chemistry World September 24, 2012 Samantha Cheung |
Tumors reprogram nylon synthesis Cancer mutations have inspired a redesign of an enzyme to catalyze a key step in the bio-based production of adipic acid, a precursor to nylon. |
Chemistry World June 17, 2010 Andrew Turley |
Biocatalyst improves diabetes drug production Researchers have developed an enzyme that can produce a difficult to form chiral amine in a best-selling diabetes therapy. |
Chemistry World August 10, 2009 James Urquhart |
Stretching for reversible enzyme activation A new kind of biologically inspired nanomaterial that can be chemically turned on and off by mechanical stretching has been devised by French researchers. |
Chemistry World August 26, 2008 Fred Campbell |
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. |
Chemistry World June 9, 2013 James Urquhart |
Hairy proteins survive stomach trip Swiss researchers have discovered a way to stabilize enzymes in the digestive tract by linking polymers to the enzymes. |
Chemistry World October 25, 2012 Philip Ball |
h is for horoscope? Named after Jorge Hirsch, the physicist who devised this measure of achievement, the h index quantifies how many highly cited papers an individual has written: h of his or her papers have been cited at least h times. Hirsch says that tenured researchers tend to have an h index of at least 12. |
Chemistry World August 13, 2007 Simon Hadlington |
Nature Captured in a Test-Tube Two groups of researchers have demonstrated how a complex chain of reactions catalyzed by multiple enzymes can be reconstructed in the test tube to synthesize naturally occurring products that have potential therapeutic properties. |
Nutra Solutions October 10, 2007 Kerry Hughes |
Products: The "Spark of Life" The potential for enzyme use has not escaped scientists' imaginations, as enzymes are used in numerous industrial and medical applications. |
Chemistry World August 13, 2009 Simon Hadlington |
Forcing enzyme activity New research has shown that physically stretching an enzyme can trigger its activity - even when the active site is not hidden in a 'cryptic' position. Mechanical force may play a more important role in biological molecular systems than previously realized. |
Chemistry World February 17, 2013 Simon Hadlington |
Enzyme nano-parcels sober up drunken mice Scientists in the US and China have invented a way to encapsulate teams of enzymes in a thin polymer shell. This enables the enzymes to carry out a series of sequential reactions within an enclosed space -- as happens in nature. |