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Chemistry World February 19, 2010 Simon Hadlington |
Forcing stereoselectivity on reactive cations Chemists in the US have devised a dual catalyst strategy to tame the highly reactive iminium ion to give a high degree of stereochemical control over subsequent reactions of the ion. |
Chemistry World July 26, 2007 Tom Westgate |
Counterion Does the Twist US chemists have achieved a breakthrough in the design of catalysts that selectively produce chiral compounds. |
Chemistry World November 17, 2008 Simon Hadlington |
Catalyst flexes for extra control US chemists have developed a new type of catalyst capable of exerting high stereochemical control over olefin metathesis reactions |
Chemistry World September 20, 2007 Lewis Brindley |
New Catalyst Rings the Changes Organic chemists in the US have developed a method to control the stereochemistry of a useful intramolecular Diels-Alder reaction. |
Chemistry World February 21, 2008 Lewis Brindley |
Esters Made Easy with Indium Indium is the basis of a novel catalyst designed to make useful cyclic esters. This catalyst could greatly simplify the production of chiral dihydropyranones, important structural elements in many natural products and pharmaceuticals. |
Chemistry World October 16, 2015 Philippa Matthews |
One pot recipe for incompatible catalytic transformations Researchers from the US have demonstrated a new catalyst support structure allowing two incompatible catalysts to work in tandem. |
Chemistry World June 1, 2006 Michael Gross |
New Twists on Catalysis Chemists around the world have discovered several new twists to improve the performance of asymmetric catalysts in hydrogenation reactions. |
Chemistry World May 9, 2010 Phillip Broadwith |
Iron catalyst breaks the mold An iron catalyst that is not only greener than many of its precious metal competitors, but also catalyses reactions that they can't, could open new avenues in transition metal catalysis, say Chinese researchers. |
Chemistry World March 25, 2011 Simon Hadlington |
New synthesis for chiral anticancer compound The promising anticancer compound nutlin-3 is likely to become more widely available to researchers thanks to a new synthetic protocol developed by US chemists. |
Chemistry World September 6, 2006 Michael Gross |
Selective Shortcut Chemists have developed a simple catalyst that speeds up the synthesis of a chiral protected building block used in many complex syntheses. |
Chemistry World April 25, 2014 Derek Lowe |
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. |
Chemistry World June 10, 2010 Phillip Broadwith |
A green and salty chiral catalyst An efficient, chiral, salt-based hypervalent iodine catalyst has been discovered by Japanese chemists that could replace toxic metal catalysts without generating the waste or explosion risks associated with hypervalent organo-iodine complexes. |
Chemistry World July 3, 2015 Andy Extance |
Copper catalysis overcomes double bond trouble Some carbon-carbon double bonds seem too unreactive for synthetic use -- but that's just how chemists in the US are now exploiting them. |
Chemistry World October 18, 2011 Steve Down |
Cofactor Control of Catalysis Enantioselectivity Scientists have used cofactors to control the enantioselectivity of supramolecular transition metal catalysts, enabling the asymmetric hydrogenation of a series of acrylates and related compounds with remarkably high selectivities. |
Chemistry World March 8, 2011 Jon Cartwright |
Carbon nanotubes - a boon for chiral catalysts Researchers in China have created a new catalyst that could help in the production of chiral molecules for medical drugs. The catalyst, which consists of platinum nanoparticles encapsulated in carbon nanotubes, is the most active of its type ever reported. |
Chemistry World January 6, 2010 Phillip Broadwith |
Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain. |
Chemistry World September 22, 2015 Andy Extance |
Firming COFs up takes Michael reaction catalysis forward By making formerly fragile covalent organic frameworks resistant to harsh conditions, researchers have created what they think could be a powerful new catalyst concept. |
Chemistry World December 17, 2009 Simon Hadlington |
Single catalyst gives two products from racemic mixture Chemists in the US have demonstrated a remarkable reaction in which a single catalyst can transform a racemic mixture - molecules identical in every way except for their chirality - into two distinct enantiomerically pure products. |
Chemistry World April 19, 2009 Hayley Birch |
Chiral metals shape up for catalysis Dutch and Israeli scientists have found a way to induce the chirality usually only found in organic materials in palladium. |
Chemistry World September 4, 2008 Fred Campbell |
Two catalysts better than one US researchers have cracked a long standing problem in chemical synthesis - the catalytic alpha-alkylation of aldehydes - by combining two catalysts in one pot. |
Chemistry World November 28, 2013 Andy Extance |
Base metal catalysts strike hydrogenation gold Three teams have shown that chemists need not rely only on expensive and toxic precious metal catalysts for hydrogenation -- they've found complementary alternatives based on cheap, abundant and safer transition metals. |
Chemistry World January 8, 2014 Karl Collins |
Oxidation station Small molecules are making significant inroads -- with reactivity and selectivity approaching levels previously thought unachievable. |
Chemistry World October 1, 2014 Karl Collins |
Twisting activity from amides When I think of asymmetric aldol reactions, what immediately springs to mind is using boron to control enolate geometry and chiral auxiliaries to impart facial selectivity in the addition step. |
Chemistry World December 23, 2015 Karl Collins |
Scratching chiral surfaces There are numerous challenges to developing reactions that exploit chiral surfaces, or employ molecular modifiers (ligands) to create a chiral surface environment and control the stereoselectivity of a transformation. |
Chemistry World January 29, 2014 |
Organic matter: Indoxamycins A, C and F In 2012, Erick Carreira's group in Zurich reported the total synthesis of indoxamycin B. 1 This 24-step organometallic tour de force resulted in a structural reassignment and set the bar rather high for future work on this family. |
Chemistry World February 6, 2015 Elisabeth Ratcliffe |
Exploiting the chirality of DNA DNA has emerged as an innovative way of controlling the chirality of a reaction product by binding catalysts in such a way that one enantiomer is preferentially generated. |
Chemistry World July 16, 2013 Harriet Brewerton |
Accelerating stereochemical analysis A chemosensor has been developed by scientists in the US to speed up the quantitative stereochemical analysis of chiral amino alcohols and diamines. |
Chemistry World February 20, 2012 James Urquhart |
Unusual kinetics of catalyst revealed US researchers have elucidated the unusual reaction kinetics of C-H activation by the palladium(II) catalyst (Pd(OAc) 2). |
Chemistry World November 26, 2012 Laura Howes |
Protein coat prepares catalyst for cascades By protecting a transition metal catalyst with a protein coat, scientists have managed to couple up biocatalysts and chemical catalysts to perform a cascade reaction. |
Chemistry World September 13, 2013 Anthony King |
Spinning a catalytic yarn Scientists in Germany have revealed a revolutionary new support for catalysts -- cloth. They succeeded in permanently securing organocatalysts onto nylon using ultraviolet light, without any need for chemical modification. |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World June 17, 2010 Andrew Turley |
Biocatalyst improves diabetes drug production Researchers have developed an enzyme that can produce a difficult to form chiral amine in a best-selling diabetes therapy. |
Chemistry World February 27, 2011 Manisha Lalloo |
Catalyst cleans up C-C bond formation Researchers in the US have developed an iridium catalyst that promotes carbon-carbon bond formation between methanol and allenes. |
Chemistry World December 5, 2012 Phillip Broadwith |
Chemical reactions in hot water Chinese and Japanese chemists have highlighted hot water's ability to promote unexpected reactions without any other reagents or catalysts. The work should expand our understanding of how to harness the physicochemical properties of water to potentially replace more complex reagents and catalysts. |
Chemistry World December 3, 2014 Cally Haynes |
One rotaxane, two catalytic stories A two-site supramolecular catalyst that can be programmed to mediate different reactions depending on its conformation has been designed by researchers in the UK. |
Chemistry World February 11, 2008 Lewis Brindley |
Oxidation Goes Green A new 'green' strategy for making useful nitrogen-based chemicals has been announced by chemists in the UK. |
Chemistry World June 23, 2011 Simon Hadlington |
Breaking the carbon-fluorine bond US chemists have discovered a new way to break the bond between carbon and fluorine atoms - the strongest carbon bond there is. |
Chemistry World March 23, 2009 Hayley Birch |
Speeding up screening for chiral catalysts U.S. researchers say their method represents a 'standard workhorse' for discovery and optimisation of chiral catalysts, such as those widely used by the pharmaceutical and pesticide industries. |
Chemistry World August 20, 2008 |
Gold's Magic Number A new gold catalyst developed by UK chemists can catalyse hydrocarbon oxidation, using O 2 as the only oxidant. But catalyst particle size is critical - above 2nm diameter, the catalyst loses all activity. |
Chemistry World April 25, 2010 Hayley Birch |
New strategy yields best ever catalyst for ammonia decomposition US researchers have developed a new strategy for predicting bimetallic catalysts. |
Chemistry World April 4, 2008 James Mitchell Crow |
More to Catalysis Than Meets the Eye Catalysts are more than just a reactive surface. Changes beneath a metal's skin can completely change the course of a reaction. |
Chemistry World April 6, 2009 Nina Notman |
Torn catalysts help polymers heal themselves Catalysts that are activated by a mechanical force tearing them in two have been designed by Dutch scientists. |
Chemistry World June 13, 2008 Richard Van Noorden |
Asymmetric ketone catalysis gets pharma-scale makeover An asymmetric catalysis reaction limited to laboratory syntheses has received a makeover that could see it used on a large scale by drug-makers. |
Chemistry World April 18, 2012 Elinor Richards |
Homogeneous Catalyst Recovery Made Easier Scientists have now found a way to recover homogeneous catalysts at the end of a chemical reaction that doesn't suffer from the slow reaction rates that affect current catalyst recovery systems. |
Chemistry World October 3, 2008 Lewis Brindley |
Nanotube catalysts improve industrial reaction A catalyst consisting of modified carbon nanotubes makes an important industrial reaction milder, safer and more selective, according to researchers in Germany. |
Chemistry World December 12, 2007 Jonathan Edwards |
Aqueous Fischer-Tropsch is Clean and Green Chinese chemists have carried out the Fischer-Tropsch reaction in water for the first time, bringing a greener route to hydrocarbon fuels a step closer. |
Chemistry World March 20, 2007 Tom Westgate |
Is Your Lab Ready to go Veggie? In a recently published review article, Geoffrey Cordell demonstrates that the greengrocer's could be an unexpected goldmine of sustainable, cheap reagents that would benefit chemistry in developing countries. |
Chemistry World February 21, 2007 Tom Westgate |
Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules. |
Chemistry World May 15, 2014 Jenifer Mizen |
Freeze-dried cells make better biocatalysts A biocatalytic cascade using mashed-up cells has overcome extraction and solubility problems associated with using enzymes in chemical syntheses. |
Chemistry World March 21, 2007 Richard Van Noorden |
Forcing a Reaction US chemists have forced molecules to react by ripping their bonds apart with ultrasound. The scientists carefully stretched one targeted bond until it snapped, guiding the molecule's subsequent reaction into pathways forbidden by conventional chemistry. |