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Chemistry World June 1, 2014 Tim Wogan |
Squid skin conductor for bioelectronics A protein from squid skin is a good conductor of protons, researchers in California have discovered. |
Chemistry World December 19, 2007 Simon Hadlington |
Snapshot of Proteins Linked to Autism Researchers in France and the US have caught on camera the gentle embrace between two proteins that sit on either side of the junction between nerve cells. It's this short circuit that has thought to cause some types of autism. |
Chemistry World June 27, 2010 Simon Hadlington |
Nanoparticles allow remote control of cells In an experiment reminiscent of the mind-control rays that featured prominently in B-movies from the 1950s, scientists in the US have used a magnetic field to alter the behavior of an animal. |
Chemistry World February 13, 2012 Andy Extance |
Protocells called thermal springs home The first 'protocells' may have arisen in puddles of liquid spewed onto the ancient Earth's surface by thermal springs rather than near deep sea hydrothermal vents. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
Chemistry World June 13, 2010 Lewis Brindley |
Novel 'cell wires' to patch up heart or nerve damage Noodle-like strings containing living cells have been made by researchers in the US. |
Chemistry World August 2, 2011 Kate McAlpine |
Hacking into chemical cell phone calls US researchers have made a nanodevice that can eavesdrop on a cell's mutterings, and they say it could be adapted to listen in on conversations between cells. |
Chemistry World September 1, 2011 Josh Howgego |
Small molecules open gates to the brain New tools have been developed which make it possible to chemically shut down nerve cells in the brain at will and study the effects on behavior. The tools - modified ion channels - mean the causal relationship between individual nerves and behavior can be directly studied. |
Chemistry World August 15, 2007 John Bonner |
Chemists Claim Biological Alchemy South Korean chemists say they have turned muscle cells from the sole of a human foot into something akin to stem cells, using a simple molecule called neurodazine. |
Chemistry World |
Fishing for Chemical Answers to Biological Questions James K. Chen talks about chemical biology, his love for the outdoors and fly fishing. |
Chemistry World February 12, 2009 Simon Hadlington |
Mystery receptor's binding partner uncovered For decades scientists have puzzled over the role of the sigma-1 receptor, a protein found in almost all mammalian cells, including the nervous system. |
HHMI Bulletin May 2010 Ivan Arnato |
Light Moves Light is becoming the tool of choice for researchers who want to precisely manipulate neurons and other cells. |
Chemistry World October 7, 2012 David Bradley |
Magnetic nanoparticles zap cancer Nanoparticles can be used as a remote-controlled magnetic death switch to kill cancer cells, according to researchers from Korea. |
Chemistry World January 13, 2010 Simon Hadlington |
Click chemistry reveals sugar synthesis in live animals US researchers have used 'click chemistry' to attach chemical tags to complex sugar molecules in the cells of live mice, allowing the synthesis of the sugars - glycans - within the cells to be tracked. |
HHMI Bulletin Winter 2013 Sarah C.P. Williams |
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. |
Chemistry World July 13, 2009 Lewis Brindley |
Getting a look at water wires Indian chemists have trapped tiny strands of water inside peptide nanotubes - allowing the researchers to take a direct look at how small amounts of water behave in a confined environment. |
Chemistry World May 17, 2007 Richard Van Noorden |
Bacterial Navigation Reprogrammed U.S. scientists have forced bacteria to follow new chemical signals by tweaking the bugs' natural guidance system. |
Chemistry World October 9, 2011 Simon Hadlington |
New probe throws light on cellular lipids Scientists in the US have developed a new sensor that can track and measure lipids in living cells. |
Chemistry World February 21, 2013 Akshat Rathi |
NO for longevity US researchers may have direct evidence for nitric oxide's apparent special powers, at least in the nematode model organism Caenorhabditis elegans. |
Chemistry World April 2010 |
Column: The crucible We are getting better at manipulating cells to grow into the tissues we need. Chemical factors are key, says Philip Ball |
HHMI Bulletin Winter 2013 Amber Dance |
A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery. |
Chemistry World November 12, 2009 Hayley Birch |
New drug design looks top Notch against cancer A new type of drug that can block the switching on of certain genes in cancer cells has shown promise in mice. |
Chemistry World June 1, 2009 Phillip Broadwith |
Wider therapeutic possibilities for botulinum toxin Change to a single amino acid in botulinum toxin A causes it to target non-neuronal signalling proteins, potentially widening the product's therapeutic applications |
HHMI Bulletin May 2012 Elise Lamar |
Cells on the Move The biochemical signals that set cells on a journey are as diverse as the tissues they move through, but the engine is driven by constant remodeling of a protein network built from a box of cellular Legos. |
Chemistry World September 21, 2010 Hayley Birch |
Self-pumping membrane mimics cell machinery US researchers have imitated the transport functions of biological membranes by incorporating tiny pumps into synthetic membranes. They say their 'self-pumping' mimics could be used in compartment-less fuel cells. |
Chemistry World March 6, 2011 Mike Brown |
Molecules that walk, hop and jump 'Two legged' molecules walk, hop and fly across a receptor surface, according to researchers in the Netherlands and Ireland. The findings could help us understand how viruses and bacteria interact with cell membranes, they say. |
Chemistry World June 28, 2006 Katharine Sanderson |
Insecticide Acts on Insect Muscles Researchers at DuPont have discovered a range of potent insecticides: the anthranilamides. These nitrogen-containing aromatic compounds are selective targets of the ryanodine receptor in insects. Ryanodine receptors are calcium ion channels used in muscle function. |
HHMI Bulletin Nov 2011 Sarah C. P. Williams |
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. |
Chemistry World April 19, 2011 Simon Hadlington |
Cell factories package drugs for delivery Scientists in Australia and Germany have used living cells as 'factories' to encapsulate particles such as drugs in biological membranes. |
HHMI Bulletin Feb 2012 Nicole Kresge |
Now You See It, Now You Don't A disappearing receptor could hold the key to beta-cell growth and insulin production. |
Chemistry World June 2, 2006 Jon Evans |
Axons Get Directions Scientists are a step closer to understanding the processes that control the growth and spread of nerve cells, following the discovery of a protein complex that directs the transport of building material to growing axons. |
Chemistry World December 9, 2013 James Urquhart |
Drug fix for misfolded proteins promises hope for incurable diseases Researchers have been looking into pharmacological chaperones or pharmacoperones. They might treat diseases brought about by genetic mutations that cause otherwise functional proteins to become misfolded or misrouted. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. |
Chemistry World February 2007 Philip Ball |
The Crucible Molecular biology isn't just about the cleverness of proteins and nucleic acids. Even the molecules often assumed to be just part of the scaffolding, such as lipids, and the very water that bathes them all, may have inventive roles to play. |
HHMI Bulletin Fall 2012 Megan Scudellari |
In Living Color Vikas Gupta and Kenneth Poss created dozens of zebrafish with vibrantly colored cardiomyocytes and then examined the fish hearts at select moments between hatching and adulthood. |
Chemistry World January 13, 2008 Ananyo Bhattacharya |
Unexpected Effects of Drug Combinations Medicines that use a combination of several drugs can sometimes produce unexpected effects in patients. Now, a team of scientists think they have figured out how that can happen. |
Chemistry World September 25, 2009 Simon Hadlington |
New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging. |
Chemistry World May 5, 2011 Simon Hadlington |
Revolutionary new single-cell labelling method Researchers in the US and Canada have combined mass spectrometry with a technique called flow cytometry to follow dozens of biochemical markers on individual cells simultaneously. |
Bio-IT World July 15, 2003 Julia Boguslavsky |
'Fingerprinting' a Single Cell Single-cell proteomics is finally within reach, thanks to a professor of analytical chemistry. |
Chemistry World January 4, 2007 Henry Nicholls |
Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
Chemistry World February 2, 2014 Emma Stoye |
Artificial membrane harvests light like a cell Photosensitive compounds built into an artificial membrane can capture light energy in the same way as proton pumps found in biological cells. |
HHMI Bulletin Aug 2011 Cassandra Willyard |
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. |
Technology Research News January 29, 2003 Kimberly Patch |
Tiny hole guides atoms against tide Researchers in Poland have made a synthetic device that uses an electrical field and an extremely small, conical pore in a thin film of material to coax potassium ions through the artificial membrane against their electrochemical potential. |
Chemistry World February 28, 2013 Andy Extance |
Chemical transport defines 'Goldilocks' cell size A US team has suggested molecular movement as an answer to the question of why cells are the size they are. A question that they say 'still awaits an answer from first principles'. |
Chemistry World October 18, 2012 |
A signal honor The 2012 Nobel prize in chemistry was awarded to Robert Lefkowitz and Brian Kobilka for studies of G-protein-coupled receptors. This article looks at the molecular machinery underpinning cell signaling. |
Scientific American May 2009 Kate Wilcox |
Free Radical Shift: Antioxidants May Not Increase Life Span Antioxidants, abundant in pomegranates, counter free radical damage but may not delay aging. |
Chemistry World October 2, 2013 Michael Parkin |
Insect-powered microtweezers Scientists in Japan have developed the first biohybrid microdevice that can function in air. The microtweezers powered by insect muscle tissue could be used to handle cells and other fragile objects as part of a microelectromechanical system. |
Chemistry World February 11, 2013 Philip Ball |
A (chemical) potential theory of life's origin This theory says that life arose at hydrothermal vents, not merely because these provide heat and the ingredients for making complex organics but because they create sustained gradients of ion concentration. |
HHMI Bulletin May 2012 Nicole Kresge |
Locating a Genetic Glitch A team of 41 scientists led by HHMI investigator Louis Ptacek has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known protein that may be responsible for communication between neurons. |