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HHMI Bulletin
Nov 2010
Sarah C.P. Williams |
Scientists Track Down Genetic Mutations In Record Time Scanning the human genome for a single disease-causing mutation is like taking a copy of War and Peace in a foreign language and searching for one misspelled word   |
HHMI Bulletin
May 2012
Sarah C. P. Williams |
Opening the Floodgates Researchers are using exome sequencing -- zeroing in on the genes that encode proteins -- to explore the biology of certain diseases. |
BusinessWeek
October 23, 2008 |
The Story in Your Genes There's tremendous value in genetic data, but it depends on how deeply you look. |
Bio-IT World
June 12, 2002
Kevin Davies |
Variations on a Theme Researchers at Genaissance Pharmaceuticals have outlined the path to creating a comprehensive map of human genomic variation that should ultimately reveal the genetic underpinnings of common diseases. |
Scientific American
June 2009
Melinda Wenner |
Genetic Copy Variations and Disease A new sense for how variable numbers of genes cause disease. |
HHMI Bulletin
May 2011
Sarah C.P. Williams |
The Pace of Evolution A close look at the human genome shows the slow and steady beat of adaptation. |
Chemistry World
July 2010
Anna Lewcock |
Medicine made to measure Healthcare tailored to suit the genetic makeup of the patient is finally coming to fruition. |
Managed Care
August 2004
Thomas Morrow |
10,000 Cells on a Chip Signal Start of New Era of Diagnosis Diseases will soon be defined by biochemical pathways and genetic interactions. Biochips may identify patients likely to respond to therapeutic agents. All of this is a big deal for health plans. |
BusinessWeek
June 13, 2005
John Carey |
The NIH's Roadmap for Research Charting the human genome was just the beginning. Now the focus is creating pathways that will lead to practical applications. |
Bio-IT World
February 18, 2004 |
The Quest for Complex Genes Genetic sleuths are homing in on genes for complex diseases with the help of new, and some not so new, tools and strategies. |
Wired
November 17, 2007
Thomas Goetz |
23AndMe Will Decode Your DNA for $1,000. Welcome to the Age of Genomics A much-anticipated Silicon Valley startup called 23andMe offers a thorough tour of your genealogy, tracing your DNA back through the eons. |
Nurse Practitioner
August 2009
Linda A. Howe |
Pharmacogenomics and management of cardiovascular disease Prior to the completion of the Human Genome Project in 2003, individual responses to medications were usually termed idiosyncrasies. Ethnic differences were not usually seen as genetic variants, as is the case today. |
American Family Physician
August 1, 2005
Wattendorf & Hadley |
Family History: The Three-Generation Pedigree The three-generation pedigree provides a pictorial representation of diseases within a family and is the most efficient way to assess hereditary influences on disease. |
American Journal of Nursing
October 2009 |
Pharmacogenomics: Personalizing Drug Therapy Pharmacogenomics is a rapidly growing field of research into the ways in which genetic variation affects drug response. |
Managed Care
May 2005
Martin Sipkoff |
Predictive Modeling & Genomics: Marriage of Promise and Risk Integration of predictive modeling and genomic tools means improved technology, enhanced databases, and appropriate legal guidance. |
Bio-IT World
June 17, 2004
Michael A. Goldman |
A Hip Approach to Gene Hunting IntegraGen defines the genetic blueprint of complex human diseases and delivers validated disease markers and therapeutic targets for a better diagnosis and a causal treatment of common diseases, based on its unique genomic analysis expertise. |
Bio-IT World
November 14, 2003
Jeff Augen |
Making Information-Based Medicine Work A confluence of scientific discovery and high-throughput technology has made information-based medicine possible -- and imperative. |
Salon.com
May 1, 2000
Arthur Allen |
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. |
Chemistry World
January 20, 2011
James Urquhart |
SNPs on display DNA origami and atomic force microscopy have been combined to reliably detect and image single nucleotide polymorphisms, the most common form of genetic variation in the human genome. |
The Motley Fool
October 27, 2010
Ralph Casale |
Companion Diagnostics in Cancer Drug Development Diagnostic companies partnering with drug developers can make for an attractive investment segment. |
Bio-IT World
October 9, 2002
Malorye Branca |
The Path to Personalized Medicine The tactics have changed, sometimes dramatically, but hints of the promise of pharmacogenomics are finally starting to trickle in from studies of asthma, cancer, and drug response. |
Bio-IT World
October 9, 2002
Kevin Davies |
Affairs of the Heart A newly discovered SNP in the cardiac sodium channel is unusually common in people of African descent, and may predispose them to potentially life-threatening arrhythmias in conjunction with other risk factors. |
Bio-IT World
November 14, 2003
Kathy Ordonez |
Targeted Medicine via Molecular Diagnostics Using diagnostics to select and deselect target populations for drug therapy will enable life scientists to make more effective medicines. |
Bio-IT World
July 2005
Kevin Davies |
Medicine Gets Personal Touch More genomics-based drugs are moving into development with others, such as new cancer drugs showcasing on the clinical pharmacogenics scene as outlined in the Advances in Genomic Medicine program of a recent world conference. |
Fast Company
November 2009
David H. Freedman |
The Gene Bubble: Why We Still Aren't Disease-Free When the human genome was first sequenced nearly a decade ago, the world lit up with talk about how new gene-specific drugs would help us cheat death. Well, the verdict is in: Keep eating those greens. |
Chemistry World
February 22, 2011
Amaya Camara-Campos |
Repairing faulty genes Israeli scientists have developed compounds that could be better treatments for genetic diseases than current drugs. |
Popular Mechanics
November 12, 2009
Bijal P. Trivedi |
5 Animal Genomes That May Hold Cures to Human Diseases Having the genomic information will guide pharmaceutical assessments and new experimental gene therapies, many of which are being done in animals. |
HHMI Bulletin
February 2011 |
Crucibles of Dynamism Puzzling pockets of redundancy account for about 5 percent of the human genome. Investigator Evan Eichler found a way to interpret what is happening in these areas of genetic repetition. |
Reason
Aug/Sep 2000
Ronald Bailey |
Strands of Life Book Review: Genome: The Autobiography of a Species in 23 Chapters, by Matt Ridley |
Bio-IT World
September 9, 2002
Malorye Branca |
The New, New Pharmacogenomics The field of pharmacogenomics proves valuable in the battle against toxicity and late-stage drug failure -- one of the pharmaceutical industry's biggest problems. |
Bio-IT World
November 12, 2002
Kevin Davies |
DNA for Dummies? The journal Nature Genetics has just published a user's guide to the human genome -- and none too soon. |
Chemistry World
February 25, 2015
Rebecca Trager |
US opens up home DNA screening The US Food and Drug Administration has, for the first time, authorized a genetic test to be sold directly to consumers. The agency plans to ease the regulatory path for similar screening tests. |
Wired
November 2002
David Ewing Duncan |
DNA as Destiny DNA is the book of life. It's also the book of death. In the future we'll all be read cover to cover. Here's what it's like to take the world's first top-to-bottom gene scan. |
Managed Care
May 2001
Michael D. Dalzell |
Powerful Opportunities For Good and Greed Genetic advances could spawn incredible improvements in health care. Given public demand, they also pose what may be unmanageable issues of resource use... |
Wired
August 2000
Jennifer Hillner |
Area 22 The inside story of the first fully sequenced chromosome. |
Bio-IT World
Dec 2006/Jan 2007
Kevin Davies |
The One Percent Difference New research reveals a shocking new layer of human genome variation with profound implications for the future of genomic analysis and personalized medicine. |
Bio-IT World
April 15, 2003
Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
Bio-IT World
September 9, 2002
Kevin Davies |
The Debate Over Race Relations Are self-identified labels of race useful in large-scale population genetic studies? A provocative commentary from a leading Stanford University geneticist has fuelled controversy. |
Managed Care
November 2006
Maureen Glabman |
Genetic Testing: Major Opportunity, Major Problems Whether a person is likely to develop diabetes, cancer, schizophrenia, or stroke will be reasonably well predicted, and tests can also determine whether a patient will respond to a given therapy. That's the good part. |
IEEE Spectrum
March 2013
Eliza Strickland |
The Gene Machine and Me Ion Torrent's chip-based genome sequencer is cheap, fast, and poised to revolutionize medicine |
Wired
August 2003
Jennifer Kahn |
The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine. |
Chemistry World
January 12, 2015
Emma Stoye |
Protein mutant libraries to probe diseases' genetic link quickly and cheaply Researchers in the US have developed a faster and less costly way to investigate the effects of genetic mutations on proteins, which should offer new insights into hereditary diseases. |
Salon.com
August 11, 2000
Jackie Stevens |
Does capitalism make you sick? Gene studies are sexy and well funded, but they can buttress racial thinking and distract the public from the socioeconomic roots of disease. |
Fast Company
September 2000
John Ellis |
The Secret of Life The mapping of the human genome, says Craig Venter, will change science, research, medicine, politics, health insurance, and the way biology looks at the last 3 billion years of evolution. And that's just the beginning. |
Bio-IT World
June 2005
Robert M. Frederickson |
Crime Pays for DNAPrint Genomics DNAWITNESS 2.0 is used by law enforcement agencies to determine the likely genetic heritage of DNA samples obtained from crime scenes -- thereby narrowing the potential pool of suspects or victims. |
Bio-IT World
June 2006
Kevin Davies |
HapMap Project Prepares for Phase II Release The official release of the Phase II HapMap data will provide a publicly available trove of information on human genetic variation across populations that will reveal insights into the genetic basis of human disease and individual response to pharmaceuticals. |
Wired
November 17, 2007
Thomas Goetz |
What My Genome Says About Me The gene variations that lead to the most popular diseases in the U.S. |
Bio-IT World
Jul/Aug 2006
Kevin Davies |
Beyond the Last Chromosome About 700 attendees gathered Beyond Genome 2006, one of Cambridge Healthtech Institute's flagship conferences, to discuss the major technology trends in postgenomic biology, including systems biology, RNAi, proteomics, and personalized medicine. |
Information Today
January 2, 2014 |
Nature Publishing Group Announces OA Journal Nature Publishing Group agreed to co-publish Human Genome Variation, a peer-reviewed, open access journal, with the Japan Society of Human Genetics. |
HHMI Bulletin
Fall 2012
Trisha Gura |
Teaching Genomics, Plainly Students at Franklin & Marshall College, searched databases of gene sequences, engineered bacteria to shuttle mutated genes into cells, and captured images of how those cells reacted to the alterations. |
