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Chemistry World May 7, 2014 Emma Stoye |
Bacterium survives unnatural DNA transplant The first organism that can grow and replicate with an unnatural base pair in its DNA -- giving the cell six nucleotides instead of the usual four -- has been created by scientists in the US. |
Chemistry World August 23, 2011 Josh Howgego |
Expanded genetic alphabet could spell out new genes Chemists have created an artificial genetic code capable of evolving to produce new genes. The code consists of six bases, rather than the standard four, and could form the basis of randomly mutating synthetic life. |
Chemistry World July 2008 Ananyo Bhattacharya |
Sparks of creation Chemists are at the forefront of synthetic biology, the burgeoning field that could soon create artificial life. |
Wired January 2005 Oliver Morton |
Life, Reinvented A group of MIT engineers wanted to model the biological world. But, damn, some of nature's designs were complicated! So they started rebuilding from the ground up - and gave birth to synthetic biology. |
Chemistry World July 4, 2008 Emma Davies |
Creating a Second Genetic Code Japanese researchers have made artificial DNA that acts like the real thing, even forming right-handed duplexes with complementary artificial strands. |
IEEE Spectrum March 2011 Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
Chemistry World June 30, 2011 Laura Howes |
Chemically evolved bacteria European scientists have created an Escherichia coli strain with a separate genome using chlorinated DNA. |
Chemistry World October 8, 2013 Hayley Birch |
RNA mimic destined for synthetic genome US scientists have taken another step towards the goal of creating self-replicating molecules like those thought to have spawned life on Earth. The researchers made RNA-like polymers capable of copying short sections of genetic code that they suggest could act as genomes in synthetic cells. |
Scientific American November 2007 Ed Regis |
The Forgotten Code Cracker In the 1960s Marshall W. Nirenberg deciphered the genetic code, the combination of the A, T, G and C nucleotides that specify amino acids. So why do people think that Francis Crick did it? |
Chemistry World October 19, 2015 Matthew Gunther |
The house that DNA built The 2015 chemistry Nobel prize was awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar for DNA repair. |
Chemistry World May 20, 2010 Hayley Birch |
The first synthetic cell A chemically synthesised chromosome has for the first time been transplanted into a cell to produce a synthetic bacterium. |
Chemistry World January 30, 2014 Anthony King |
Unnatural DNA links click for faster synthesis Human cells can still read strands of DNA correctly if they are stitched together using linkers not found in nature, a new study shows. |
Science News September 21, 2002 Ivars Peterson |
DNA's Error-Detecting Code Chemist Donall A. Mac Donaill of Trinity College in Dublin, Ireland, has now shown that patterns inherent in the chemical makeup of DNA correspond to a digital error-detecting code. |
Wired Lucas Graves |
15th Anniversary: Scientists Chase the Miracle of Fake Life Biologist J. Craig Venter engineered a synthetic version of a real organism's entire genetic code. Here's how. |
Technology Research News December 3, 2003 Kimberly Patch |
DNA assembles nanotube transistor Scientists have caused a transistor to self-assemble from a test tube concoction of DNA, proteins, antibodies, carbon nanotubes and minuscule specks of silver and gold. The feat shows that it is possible to assemble the smallest of machines and electronic devices by harnessing DNA's properties. |
Chemistry World March 4, 2015 Thadchajini Retneswaran |
Computational chemists unpick adenine -- thymine bias A chemical model has been created to investigate the evolution of guanine -- cytosine coding regions and found that certain spontaneous mutations are more likely to arise at specific regions of DNA. |
Chemistry World February 18, 2008 John Bonner |
Flicking the Acetyl Switch A strain of Escherichia coli that can produce proteins containing an acetylated version of the amino acid lysine could help to reveal how acetylation changes the function of hundreds of proteins inside cells. |
Chemistry World November 13, 2014 Katrina Kramer |
Persuading proteins to form porous polyhedra Researchers in the US have designed a hollow cube out of naturally occurring proteins, something that was previously only possible with DNA. |
Bio-IT World August 15, 2005 Kevin Davies |
Pimp My Genome As costs plummet, the ability to rapidly synthesize and customize longer, more intricate fragments of genomic DNA opens up a plethora of applications in basic and applied biology. A commercial synthetic biology industry is beginning to take shape. |
Technology Research News June 15, 2005 Kimberly Patch |
DNA Machine Links Molecules Researchers have fashioned a nanomechanical device from DNA that can be programmed to align a series of molecules and fuse them together. The technique could potentially be used to put together designer polymers, encrypt information, and carry out computations. |
Technology Research News May 5, 2004 Kimberly Patch |
DNA Bot Targets Cancer Researchers from Israel have constructed a molecular-size computer that is programmed to find signs of cancer cells, and when they are present, dispense DNA molecules designed to eradicate those cells. |
Reactive Reports Apr/May 2005 David Bradley |
At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
Chemistry World June 9, 2008 Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Technology Research News June 29, 2005 |
Self-assembly: the natural way to make things In biology, there are a few different ways DNA molecules can be replicated and combined. |
Chemistry World August 2007 Philip Ball |
Opinion: The Crucible The twist on DNA |
IEEE Spectrum August 2012 Emily Waltz |
Reading and Writing a Book With DNA Researchers are storing digital information in the form of DNA, but is it practical? Which will get us control of massively large data: electronic or molecular memory? |
Chemistry World April 19, 2012 Andy Extance |
Polymers perform non-DNA evolution Scientists have found that six polymer alternatives to DNA can pass on genetic information, and have evolved one type to specifically bind target molecules. |
Technology Research News November 3, 2004 Kimberly Patch |
DNA in nanotubes sorts molecules Researchers have made a synthetic membrane that recognizes certain biochemical molecules and allows them to pass through. The method could be used to make biological sensors like those needed for genetics research, and to sort biological molecules, |
Chemistry World March 1, 2011 Catherine Bacon |
Unravelling chromosomes Danish scientists have used a micro device to isolate centimetre-long portions of human DNA to help study the genetic make-up of diseased cells. |
Chemistry World August 26, 2014 Andy Extance |
No-frills coats set a trend for designer viruses Dutch scientists have built a simple model of viruses' protective coats in an attempt to create viral mimics that could fight diseases, as opposed to causing them. |
Chemistry World May 2008 Philip Ball i |
Pulling our strings There is much more to DNA than that elegant double helix. The author explores the twists and tangles of chromatin. |
Chemistry World December 20, 2011 Laura Howes |
Cutting edge chemistry in 2011 With the help of an expert panel of journal editors Chemistry World reviews the ground breaking research and important trends in this year's crop of chemical science papers. |
Chemistry World January 2012 |
DNA motors on With the relentless rise of DNA nanotechnology's popularity, Emma Davies explores the role chemistry has played in its success |
Chemistry World September 4, 2013 Mark Peplow |
Synthetic biology is bursting with life The field encompasses a vast array of research themes, from creating artificial life to engineering microbes to produce medicines or fuels. Through it all, though, runs a rich seam of chemistry. |
Bio-IT World July 2005 Kevin Davies |
Synthetic Biologists Assemble Codon Devices Company Emerging leaders in the new discipline of synthetic biology have raised $13 million in first-round venture funding for the field's first commercial entity - a startup company called Codon Devices. |
Technology Research News December 15, 2004 |
DNA Makes Nanotube Transistors Researchers have harnessed the self-assembly abilities of DNA to construct field-effect transistors from carbon nanotubes. |
Chemistry World October 14, 2011 James Mitchell Crow |
Twist in the tale to improve gene therapy New insights into the physical properties of different forms of DNA could help to improve gene therapy, chemists in Spain and India say. |
Chemistry World November 27, 2013 Jennifer Newton |
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. |
Technology Research News September 24, 2003 |
Glow shows individual DNA Researchers have made a type of artificial DNA of that glows when it combines with a specific sequence of natural DNA. In principle, the method could be used to develop DNA chips that directly sense individual DNA molecules. |
Chemistry World July 2008 Mark Peplow |
Editorial: There's plenty of room in the middle Today, chemists and biologists are looking at the space between their own disciplines and asking big questions about where science at the interface might lead them. |
Technology Research News December 29, 2004 |
DNA Makes and Breaks Particle Clumps Nanotechnology is all about manipulating materials on the molecular scale. Many teams of researchers are using artificial strands of DNA to do so. |
Chemistry World March 29, 2009 Lewis Brindley |
Gene gels pump out proteins Gels made with genes incorporated into the structure could soon make protein production cheaper and easier, according to researchers in the US. |
Chemistry World July 15, 2010 Simon Hadlington |
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. |
Science News March 25, 2006 Janet Raloff |
Meat Poses Exaggerated Cancer Risk for Some People The National Toxicology Program confirmed that heterocyclic amines that form in overcooked meat can trigger colon cancer in animals and probably do the same in people. |
BusinessWeek June 25, 2007 John Carey |
On The Brink Of Artificial Life Craig Venter says success is near, but critics blast efforts to patent synthetic organisms. |
Technology Research News April 23, 2003 Kimberly Patch |
DNA motor keeps cranking Researchers have been making DNA perform all sorts of shape-changing tricks in recent years, but the need to add pieces of DNA at every step has made it a bit of a stretch to call these molecules motors. A method that keeps the process humming changes things. |
Chemistry World December 10, 2014 Emma Stoye |
Cutting edge chemistry in 2014 Highlights from last year's ground breaking chemical sciences research. |
Industrial Physicist |
Biomimetic Nanotechnology Although biomimetic nanotechnology is in its infancy, with no applications yet reaching commercialization, the barriers in some cases lie mainly in scaling up production processes to industrial levels. |
Chemistry World September 14, 2011 David Bradley |
Brewing up Synthetic Yeast Yeast with synthetic genomes could be very useful for medicinal chemists and drug companies. |