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Chemistry World January 2012 |
DNA motors on With the relentless rise of DNA nanotechnology's popularity, Emma Davies explores the role chemistry has played in its success |
Chemistry World September 26, 2006 Fiona Case |
Synchronised Delivery for DNA and Drugs Polymer capsules that can simultaneously deliver drug molecules and DNA into a cell could boost the power of cancer treatments. |
Technology Research News May 5, 2004 Kimberly Patch |
DNA Bot Targets Cancer Researchers from Israel have constructed a molecular-size computer that is programmed to find signs of cancer cells, and when they are present, dispense DNA molecules designed to eradicate those cells. |
Chemistry World March 15, 2010 James Urquhart |
All aboard the DNA nanotube Cargo-carrying DNA nanotubes that can rapidly release their load on demand have been made for the first time by Canadian researchers. |
HHMI Bulletin Spring 2013 Sarah C.P. Williams |
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. |
Chemistry World February 4, 2008 Richard Van Noorden |
DNA Cages Change Size on Demand Scientists have designed dynamic DNA cages which expand or contract on demand -- and could be used to deliver drugs, or be the moving parts of nanomachines. |
Technology Research News August 27, 2003 |
Detector senses single DNA Researchers from the University of California at Los Angeles have tapped differences in the folding characteristics of single-stranded and double-stranded DNA to make a sensor capable of detecting a single DNA molecule. |
Chemistry World May 21, 2012 Simon Hadlington |
Rewritable DNA for digital data storage A rewritable memory storage module can form the basis of a digital memory system, scientists suggest, with the cell being able to 'record' transient changes in its internal chemistry. |
Chemistry World March 1, 2011 Catherine Bacon |
Unravelling chromosomes Danish scientists have used a micro device to isolate centimetre-long portions of human DNA to help study the genetic make-up of diseased cells. |
Chemistry World October 31, 2008 Manisha Lalloo |
DNA-rewinding protein discovered US scientists have found an enzyme that rewinds sections of DNA whose strands have mistakenly come apart. |
Chemistry World January 30, 2014 Anthony King |
Unnatural DNA links click for faster synthesis Human cells can still read strands of DNA correctly if they are stitched together using linkers not found in nature, a new study shows. |
Chemistry World September 2, 2009 Phillip Broadwith |
Shining a light on DNA-binding drugs in living cells German researchers have used standard circular dichroism spectroscopy to probe interactions between drug molecules and DNA within living cells. |
Chemistry World November 4, 2011 Phillip Broadwith |
Chemists put finger on the trigger to attack cancer Hydrogen peroxide-triggered release mechanisms could help reduce the side effects of cancer drugs by keeping them safely locked up until they reach the oxidizing environment of cancer cells, say scientists in the US. |
Chemistry World May 6, 2009 Phillip Broadwith |
Nano-boxes from DNA origami Danish researchers have made a nano-sized box out of DNA that can be locked or opened in response to 'keys' made from short strands of DNA. |
Chemistry World June 9, 2008 Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Chemistry World April 3, 2008 Lewis Brindley |
DNA Read in a Trice The prospect of treatments that are tailored to fit an individual's genetic makeup is a step closer thanks to technology unveiled by US scientists. |
Chemistry World November 27, 2007 James Mitchell Crow |
A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells. |
Chemistry World July 28, 2009 Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
Technology Research News September 24, 2003 |
Glow shows individual DNA Researchers have made a type of artificial DNA of that glows when it combines with a specific sequence of natural DNA. In principle, the method could be used to develop DNA chips that directly sense individual DNA molecules. |
Chemistry World February 25, 2010 Lewis Brindley |
Nanomachinery Lights up A light-activated switch to turn nanomachines on and off has been developed by Japanese researchers. |
IEEE Spectrum March 2011 Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
Managed Care November 2003 Thomas Morrow |
Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings. |
Chemistry World October 7, 2011 Sarah Farley |
Detecting diseases with DNA sensors DNA sensors detect pathogenic and genetic diseases by binding to target DNA strands that are related to the disease and giving a signal that shows how much of the DNA is present. |
Technology Research News August 22, 2005 |
DNA Technologies The versatile DNA molecule has proven to be a powerful technological building block. Researchers have developed ways of combining DNA molecules that allow them to carry out computations in test tubes and create two-dimensional patterns and three-dimensional structures at the nanoscale. |
Technology Research News June 15, 2005 Kimberly Patch |
DNA Machine Links Molecules Researchers have fashioned a nanomechanical device from DNA that can be programmed to align a series of molecules and fuse them together. The technique could potentially be used to put together designer polymers, encrypt information, and carry out computations. |
Technology Research News March 24, 2004 |
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. |
AskMen.com Jacob Franek |
New Cancer Therapies As cancer research explodes, the availability of new and innovative interventions is expanding almost daily. |
Chemistry World April 19, 2012 Andy Extance |
Polymers perform non-DNA evolution Scientists have found that six polymer alternatives to DNA can pass on genetic information, and have evolved one type to specifically bind target molecules. |
Chemistry World October 8, 2013 Hayley Birch |
RNA mimic destined for synthetic genome US scientists have taken another step towards the goal of creating self-replicating molecules like those thought to have spawned life on Earth. The researchers made RNA-like polymers capable of copying short sections of genetic code that they suggest could act as genomes in synthetic cells. |
Chemistry World February 9, 2012 Jennifer Newton |
A new generation of tuberculosis drugs Scientists in India are targeting enzymes responsible for catalysing the formation of bonds to repair nicks in the phosphodiester backbone of DNA - called DNA ligases - to tackle the ever-growing health concern of multi-drug resistant bacteria. |
Chemistry World May 12, 2010 Mike Brown |
Molecular robots on nano-assembly lines Teams of automated programmable molecular robots working together on nanoscale assembly lines is one step closer, say scientists in the US. |
Chemistry World October 19, 2009 Simon Hadlington |
DNA stretching mystery solved A detailed understanding of the elastic properties of DNA can give scientists key insights into interactions of DNA and the proteins that carry out these manipulations. |
PC World February 1, 2002 Kuriko Miyake |
Olympus Unveils DNA Computer Rather than relying on a microprocessor, computer runs on reactions between fragments of DNA... |
Reactive Reports Issue 54 David Bradley |
Hula-Hoop DNA Amplification Periodic nanostructures made of gold nanoparticles and long DNA strands with repeated sequences have been prepared by using a technique known as "rolling circle amplification" or the "hula-hoop" technique. |
Chemistry World September 23, 2009 Simon Hadlington |
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. |
Chemistry World October 17, 2011 Hayley Birch |
Quickly sorting cells using DNA A new magnetic cell sorting technique uses principles borrowed from DNA nanodevices. The approach could help scientists rapidly separate different types of cells from complex mixtures. |
Chemistry World June 29, 2007 Lionel Milgrom |
Engineered Enzyme to Excise Aids Current HIV/AIDS treatments suppress the virus's life-cycle without curing the disease. Now, German researchers are pioneering a strategy that might help to eradicate the virus altogether. |
Chemistry World June 26, 2008 Bea Perks |
Liquid Crystals Stand up for DNA Detection Liquid crystals that realign in response to DNA can reveal subtle sequence alterations, even a single base mutation, report US scientists. |
Technology Research News June 16, 2004 |
Genes Automate DNA Machines Researchers have taken a step toward automating nanomachines with a method that allows instructions for a DNA-based machine to be contained in a gene, or another stretch of DNA. |
Chemistry World September 17, 2012 Ian Le Guillou |
Raising the curtain on single-stranded DNA Scientists have created microfluidic devices containing single-stranded DNA 'curtains' for the first time, allowing scientists to study its interactions with proteins in real time. |
Chemistry World April 18, 2010 Simon Hadlington |
First DNA rotaxane Rotaxanes are dumbbell-shaped molecules encircled by a molecular hoop that can move unhindered along the axle, trapped by the bulky stoppers at either end. These could be useful components in molecular machines. |
Chemistry World November 16, 2006 Simon Hadlington |
Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly. |
Chemistry World July 4, 2008 Emma Davies |
Creating a Second Genetic Code Japanese researchers have made artificial DNA that acts like the real thing, even forming right-handed duplexes with complementary artificial strands. |
HHMI Bulletin February 2012 Sarah C.P. Williams |
The Twists and Turns of Immunity Fred Alt has built a career making sense of the immune system -- specifically, the diverse antibodies that fight off invading molecules, from viruses to cancer cells to pollen. |
Chemistry World October 13, 2015 Simon Hadlington |
DNA movement through motor proteins measured Researchers have adapted a method for DNA sequencing to measure directly and with exquisite sensitivity the movement of a single molecule of DNA as it is drawn through specialized motor proteins. |
Technology Research News April 23, 2003 Kimberly Patch |
DNA motor keeps cranking Researchers have been making DNA perform all sorts of shape-changing tricks in recent years, but the need to add pieces of DNA at every step has made it a bit of a stretch to call these molecules motors. A method that keeps the process humming changes things. |
Chemistry World March 8, 2010 Lewis Brindley |
Molecular midwives helped birth of DNA 'Molecular midwives' - are compounds that played a crucial role in combining small nucleotide fragments into the first genetic polymeric material. |
Chemistry World June 12, 2013 Sarah Houlton |
No small success Chad Mirkin has been the driving force behind four spin-out nanotechnology companies, and has more than 850 patents to his name. Yet he describes himself as something of an accidental chemist. He is particularly proud of spherical nucleic acids. |
Chemistry World February 28, 2010 Jon Cartwright |
Reactions on DNA origami watched with AFM Chemists in Denmark have for the first time imaged chemical reactions on a DNA origami scaffold so that they can precisely attach single molecules, involving atomic force microscopy. |
Technology Research News February 11, 2004 |
Scientists brew tree-shaped DNA Researchers from Cornell University have synthesized a new type of DNA that can be used as a nanotechnology building block. |