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HHMI Bulletin
Nov 2010
Sarah C.P. Williams |
A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections.   |
Scientific American
May 2009
Melinda Wenner |
Quiet Bacteria and Antibiotic Resistance Bacteria devoted to growth instead of "quorum sensing" communication could beat antibiotic resistance. |
Chemistry World
January 8, 2015
Matthew Gunther |
New antibiotic could treat infection while dodging resistance problems A new antibiotic that can kill life-threatening bacteria -- without them appearing to be able to develop resistance to the drug -- has been discovered by a team of scientists. |
Chemistry World
December 10, 2013
Jonathan Wells |
Disarming bacteria to beat infection Researchers in Germany looking to find unprecedented ways of combating bacterial infection have demonstrated that certain small molecules can reduce the ability of Staphylococcus aureus to cause disease. |
Chemistry World
March 6, 2013
Derek Lowe |
New antibiotics: what's the hold up? Money's a factor that could be adjusted by regulatory agencies, governments, and foundations. But no amount of cash will keep resistant bacteria from being the hard targets they are. |
Chemistry World
February 19, 2013
Ian Farrell |
Analyzing bacterial metabolites A mass-spectrometry technique that can characterize and spatially resolve the metabolites produced by bacteria could lead to a better understanding of how different microbes interact with each other, and how their chemistry could be harnessed industrially. |
Chemistry World
May 12, 2011
Mike Brown |
Sugars recruited in fight against persistent infections Adding sugar to antibiotics can boost their effectiveness and prevent recurrent and chronic infections, according to researchers in the US. |
Chemistry World
September 25, 2015
Emma Stoye |
3D printer uses gel matrix to tie the knot Researchers have found a way to 3D print 'impossible' shapes -- including a thin tube tied in a knot -- out of soft materials by injecting the inks into a gel that solidifies and traps them in place. |
Chemistry World
September 12, 2006
Mark Peplow |
Bacteria Silenced by Conversation Stoppers Molecules that interrupt the chemical conversations of bacterial communities are showing early promise in beating the bugs. |
Fast Company
May 2009
Elizabeth Svoboda |
Biotechs Wage War on Superbugs With antibiotic resistance on the rise, three biotechs are developing new ways to wage war on superbugs. |
Scientific American
June 2008
Melinda Wenner |
Jeremy Nicholson's Gut Instincts: Researching Intestinal Bacteria The body and its intestinal flora produce chemicals with hidden health information, Jeremy Nicholson has found. Someday treating disease may mean treating those bacteria. |
Wired
April 2003
Steve Silberman |
The Bacteria Whisperer Bonnie Bassler discovered a secret about microbes that the science world has missed for centuries. The bugs are talking to each other. And plotting against us. |
Chemistry World
September 11, 2013
Andria Nicodemou |
Bacteria incriminated by their odor Researchers in Taiwan and the US have developed a device that uses the volatile organic compounds released by bacteria to identify the bacteria as they are cultured. |
Chemistry World
November 5, 2013
Emma Stoye |
Copper signals warn bacteria of antibiotic assault Copper is known for its antimicrobial properties, but new research suggests that copper signalling within bacterial cells may also play an important role in antibiotic resistance. |
Chemistry World
July 28, 2008
Hayley Birch |
Biofilms deploy chemical weapons When marine bacteria join together in sticky biofilms, they produce lethal chemicals to protect themselves from predators. |
Chemistry World
September 24, 2015
Harriet Brewerton |
Antibiotics pit against bacterial biofilms Scientists in the US have designed a simple and inexpensive electrochemical device that monitors bacteria metabolites to gauge the effect of antibiotics. |
Chemistry World
September 19, 2008
John Bonner |
Filling the antibiotic gap Resistance to currently available antibacterial drugs is causing growing concern among doctors who find themselves unable to treat common infections |
Chemistry World
October 29, 2013
Harriet Brewerton |
Paper device spots antibiotic-resistant bacteria Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas. |
Chemistry World
May 6, 2015
Matthew Gunther |
Zombie cells may rise up to kill infections The worst fears of Hollywood may yet become a reality as chemists in Israel have found dead bacteria, killed with silver, may be able rise up like 'zombies' and go on to kill surviving pathogens. |
Chemistry World
April 27, 2011
Carol Stanier |
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. |
American Family Physician
October 1, 2006 |
Antibiotics: When They Can and Can't Help What are antibiotics?... Do antibiotics always work?... What is bacterial resistance?... What can I do to help myself?... etc. |
Chemistry World
February 6, 2013
Harriet Brewerton |
Diagnosing bacterial growth Antibiotics are used regularly for treating bacterial infections, but there is currently no quick and simple test to determine the most effective type or dose of antibiotic for a specific patient infection. |
Chemistry World
October 31, 2012
Ian Le Guillou |
A cell for a cell If you ever need to isolate a single bacterial cell, why not build it a prison cell? This is the approach that colleagues from Sandia National Laboratories, US, have taken. Using multi-photon lithography, they can construct four walls and a roof around a single cell in just over a minute. |
Reactive Reports
March 2005
David Bradley |
Microbial Manufacturing A bacterium is a microscopic chemical factory producing antibiotics, immunosuppressants, and anticancer drugs no chemist can synthesize. but pharmaceutical companies have been tapping into microbial drug manufacturing for some time. |
Chemistry World
June 28, 2013
Emma Stoye |
Antibiotic killing mechanism debate continues Antibiotics can kill bacteria without the need for reactive oxygen species. That's the claim of new research, which has added new evidence into the emerging debate over how antibiotics exert their lethal effects. |
Chemistry World
March 8, 2013
Simon Hadlington |
Battleground develops over antibiotic killing mechanism Two recent papers will require many in the field to re-examine and re-open the question of whether or not several different classes of bactericidal antibiotics do or do not work through a common mechanism. |
Chemistry World
February 11, 2011
Leanne Marle |
Fighting back against antibiotic resistant bacteria Scientists in Japan have revealed how vancomycin dimers are effective against vancomycin-resistant bacteria. |
Chemistry World
March 8, 2007
Simon Hadlington |
Researchers Claim Antibiotic Holy Grail Researchers in Canada have revealed the structure of a key enzyme involved in the synthesis of bacterial cell walls. The finding opens up the possibility of developing new and improved antibiotics and overcoming the increasing problem of bacterial resistance to existing drugs. |
Chemistry World
December 15, 2015
Michaela Muehlberg |
Bacterial identification gets a culture shock Scientists in the UK have developed a new tool to distinguish bacterial strains from each other. |
Chemistry World
March 3, 2009
Lewis Brindley |
Sweet-toothed bacteria make their own vaccine With careful feeding, bacteria can produce vaccines against themselves, scientists in the US and China have found. |
Chemistry World
March 19, 2007
Lionel Milgrom |
Gallium-Based Antimicrobials Antibiotic-resistant bacteria can be killed with gallium. US researchers used gallium as a 'Trojan horse' to fool bacteria into thinking they were feeding on iron. Bacteria need iron to survive, but they cannot distinguish between iron and gallium. |
Chemistry World
January 20, 2014
Martha Henriques |
Fast test classifies meningitis bacteria Researchers in the UK have developed a new method that uses surface enhanced Raman scattering to quickly identify which meningitis causing bacteria is responsible for an infection. |
Chemistry World
May 29, 2014
Carla Pegoraro |
Dual warhead kills and disarms bacteria A compound that kills bacteria and cleaves their DNA to prevent them passing on drug-resistant genes has been designed by researchers in India. |
Chemistry World
February 3, 2014
Jonathan Wells |
Shining a light on hospital wastewater Researchers in Portugal looking to find new ways to inactivate multidrug resistant-pathogenic bacteria have found an alternative to the traditional expensive and often ineffective methods for treating hospital effluent. |
Chemistry World
October 4, 2012
Emma Eley |
Bacterial growth is inhibited by broccoli Chemists from Israel say that the isothiocyanates sulforaphane and erucin, found in brassicaceae vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower, inhibit growth of the disease-causing bacteria Pseudomonas aeruginosa. |
HHMI Bulletin
Aug 2010
Sarah C.P. Williams |
Gut Bacteria Do More Than Digest Food Someone can blame their diabetes or inflammatory bowel disease on the churning mass of bacteria that lives inside their intestines, but there's no magic pill to change the dynamics of that complicated world of the human microbiome. |
Chemistry World
July 15, 2010
Matt Wilkinson |
Biotechs plot path of least resistance Biopharmaceutical companies are moving into antibiotics, and filling the void left by big pharma. |
Chemistry World
December 4, 2009
Lewis Brindley |
Potent two-pronged antibiotic provides hope for future drugs A two-headed compound obtained from soil bacteria may hold the key to developing the next generation of antibiotics, researchers in the UK report. |
Nutrition Action Healthletter
May 2000 |
Magic Bullets Under Siege ...Antibiotics---drugs that kill bacteria---account for much of our success in the war against infectious illness. But the miracle drugs of medicine are in danger... |
IEEE Spectrum
February 2009
Monica Heger |
Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics |
AskMen.com
Harold Russell |
The Lowdown On Superbugs The overuse and misuse of antibiotics has led to the development of resistant strains of bacteria, commonly referred to as superbugs. |
Wired
September 25, 2007 |
Three Smart Things You Should Know About Bacteria The benefits of bacteria. |
Chemistry World
May 17, 2007
Richard Van Noorden |
Bacterial Navigation Reprogrammed U.S. scientists have forced bacteria to follow new chemical signals by tweaking the bugs' natural guidance system. |
Chemistry World
April 3, 2008
Philip Ball |
Antibiotic-Eating Bacteria Found in Soil Scientists in the US have found that soil is full of bacteria that will feed and grow on antibiotics the very compounds created to kill them. |
Chemistry World
February 24, 2010
Hayley Birch |
Marine microbes wired up A new study provides evidence for the existence of naturally occurring electric circuits orchestrated by marine bacteria. |
Chemistry World
January 30, 2015
Rebecca Trager |
Billion dollar package unveiled to fight antibiotic resistance President Obama has made a huge investment in the fight against antibiotic resistant bacteria |
Wired
May 22, 2009
Erin Biba |
New Germ Busters Outwit Antibiotic-Resistant Bacteria Researchers are testing new bug-killers that bypass the molecular pathways used by old-school antibiotics. |
Bio-IT World
Jul/Aug 2006
Robert M. Frederickson |
Tests for Hospital-Acquired Infections Tests for pathogens increasingly rely on genomic methods that identify specific genetic signatures of bacteria or viruses. Rapid detection of other pathogens also provides the potential for significant impact on the healthcare industry. |
Chemistry World
August 27, 2014
Hayley Simon |
Ionic liquids join battle against antibiotic resistance US researchers have used ionic liquids -- organic salts that are liquid at room temperature -- to disrupt bacterial biofilms and deliver antibiotics through the skin's outer layer. |
Chemistry World
August 27, 2014
Richard Massey |
Fluorinating new life into an increasingly ineffective antibiotic A fluorinated analog of the naturally occurring aminoglycoside neomycin -- well known as an over-the-counter ointment for minor skin abrasions -- could lead to a range of much-needed antibiotics |
