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Chemistry World
November 28, 2006
Michael Gross |
Synthesis Success After 30 Years Chemists at Harvard have succeeded in synthesizing the antibiotic moenomycin A from scratch. They hope that by providing easier access to this molecule and its variants, they might aid the development of new antibiotics based on its structure.   |
Chemistry World
April 4, 2011
Carol Stanier |
Mighty micelles that make themselves Scientists in the US and Singapore have made self assembling micelles of cationic polymers that kill bacteria but are biodegradable - raising further hope of a nanotechnology solution to the problem of antibiotic resistance. |
Chemistry World
March 8, 2007
Simon Hadlington |
Researchers Claim Antibiotic Holy Grail Researchers in Canada have revealed the structure of a key enzyme involved in the synthesis of bacterial cell walls. The finding opens up the possibility of developing new and improved antibiotics and overcoming the increasing problem of bacterial resistance to existing drugs. |
The Motley Fool
May 12, 2004
Charly Travers |
Cubist Addresses a Niche Market This small firm is developing antibiotics to meet a medical need. |
Chemistry World
October 13, 2006
Richard Van Noorden |
Fastest Synthesis in the West A promising antibiotic with a novel mechanism of action has been synthesized for the first time -- and with impressive speed. |
Chemistry World
January 8, 2015
Matthew Gunther |
New antibiotic could treat infection while dodging resistance problems A new antibiotic that can kill life-threatening bacteria -- without them appearing to be able to develop resistance to the drug -- has been discovered by a team of scientists. |
Chemistry World
May 12, 2011
Mike Brown |
Sugars recruited in fight against persistent infections Adding sugar to antibiotics can boost their effectiveness and prevent recurrent and chronic infections, according to researchers in the US. |
Chemistry World
August 11, 2014
Phillip Broadwith |
Single shot antibiotic approved for skin infections Intravenous antibiotic Orbactiv oritavancin, from US firm The Medicines Company, has been approved by the US Food and Drug Administration. |
HHMI Bulletin
Nov 2010
Sarah C.P. Williams |
A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections. |
Chemistry World
October 29, 2013
Harriet Brewerton |
Paper device spots antibiotic-resistant bacteria Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas. |
IEEE Spectrum
February 2009
Monica Heger |
Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics |
AskMen.com
Jacob Franek |
Superbugs So long as antibiotic use remains widespread and excessive, superbug bacteria will be here with us. Read on about some of the most common North American superbugs. |
Chemistry World
October 13, 2008
Hayley Birch |
Cantilevers bend over for drug detection Arrays of flexible microcantilevers - micrometre-thin diving boards - can be used as sensors to detect binding interactions between drugs and their targets |
The Motley Fool
January 13, 2004
David Nierengarten |
Vicuron's Booster Shot With a new "super-tough" antibiotic, Vicuron's stock is super high. |
Nutrition Action Healthletter
November 1999
Michael F. Jacobson |
Fighting Superbugs For more than 30 years, doctors have used the antibiotic vancomycin when all others have failed. Now vancomycin itself is starting to fail, and its successor, synercid, is already encountering resistant germs. A change in U.S. agricultural policy may be able to stem that process... |
Chemistry World
October 8, 2013
David Bradley |
3D printing bacteria Jason Shear and colleagues at the University of Texas, US, have developed a 3D printing technique that lets them 'construct' defined bacterial communities so that short-range chemical communications and physical interactions between bacteria can be investigated more systematically than ever before. |
Wired
September 25, 2007 |
Three Smart Things You Should Know About Bacteria The benefits of bacteria. |
Nutrition Action Healthletter
May 2000 |
Magic Bullets Under Siege ...Antibiotics---drugs that kill bacteria---account for much of our success in the war against infectious illness. But the miracle drugs of medicine are in danger... |
Chemistry World
November 24, 2011
Elinor Richards |
Blocking cancer's path A concise synthesis of the natural product rasfonin could reignite interest in this molecule as a tool to develop cancer drugs, say scientists from the Netherlands. |
American Journal of Nursing
June 2008
Mary C. Vrtis |
Is Your Patient Taking the Right Antimicrobial? Ways in which bacteria become resistant to antimicrobials and the prevalence and costs of health care-associated infections resulting from antimicrobial resistance. |
BusinessWeek
April 12, 2004
Catherine Arnst |
Killer Staph Is Hitting The Streets For the past 30 years, hospitals have been battling a mutant form called methicillin-resistant S. aureus (MRSA) that is resistant to penicillin-related antibiotics and is especially lethal. Now it's showing up in the general population. |
American Family Physician
February 15, 2002
Paul W. Ament |
Linezolid Its role in the treatment of gram-positive, drug-resistant bacterial infections... |
Chemistry World
March 6, 2013
Derek Lowe |
New antibiotics: what's the hold up? Money's a factor that could be adjusted by regulatory agencies, governments, and foundations. But no amount of cash will keep resistant bacteria from being the hard targets they are. |
Chemistry World
December 15, 2015
Michaela Muehlberg |
Bacterial identification gets a culture shock Scientists in the UK have developed a new tool to distinguish bacterial strains from each other. |
American Family Physician
December 15, 2005
Bamberger & Boyd |
Management of Staphylococcus aureus Infections Because of high incidence, morbidity, and antimicrobial resistance, Staphylococcus aureus infections are a growing concern for family physicians. |
Scientific American
January 2007 |
Meet Resistance Head-On With resistance to antibiotics growing at an alarming pace among pathogenic bacteria, Americans must become more aggressive with regard to early intervention in the processes that foster resistance. |
Chemistry World
September 11, 2013
Andria Nicodemou |
Bacteria incriminated by their odor Researchers in Taiwan and the US have developed a device that uses the volatile organic compounds released by bacteria to identify the bacteria as they are cultured. |
American Family Physician
December 1, 2001
John P. Manzella |
Quinupristin-Dalfopristin: A New Antibiotic for Severe Gram-Positive Infections Quinupristin-dalfopristin is a streptogramin. This class of antibiotics is an important addition to the options available for the treatment of severe infections caused by gram-positive organisms... |
Chemistry World
December 10, 2013
Jonathan Wells |
Disarming bacteria to beat infection Researchers in Germany looking to find unprecedented ways of combating bacterial infection have demonstrated that certain small molecules can reduce the ability of Staphylococcus aureus to cause disease. |
Chemistry World
August 1, 2013
James Urquhart |
Total synthesis outshines biotech route to anticancer drug US scientists have developed the first efficient and scalable route for the total synthesis of ingenol -- a plant-derived diterpenoid used to treat precancerous skin legions. |
Chemistry World
December 17, 2012
Jessica Cocker |
Helping the fight against flu Scientists from Australia and the US have developed a synthesis for a drug that gives higher yields and antiviral activity than currently used commercial drugs, such as Relenza (zanamivir) and Tamiflu (oseltamivir), they claim. |
Chemistry World
April 25, 2007
Richard Van Noorden |
Malaria Drug Cures Mice with Single Dose U.S. chemists have adapted a Chinese herbal medicine to create a new generation of antimalarial drugs which could solve some of the current crop's failings. |
Nursing
March 2010
Delahanty & Myers |
3 bad bugs Acinetobacter baumannii, Panton-Valentine leukocidin positive methicillin-resistant Staphylococcus aureus, and infections that develop as a result of antimicrobial therapy, such as Clostridium difficile. |
Chemistry World
April 2007
Derek Lowe |
Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort? |
Chemistry World
August 2010
Paul Docherty |
Column: Totally Synthetic The total synthesis of macrolide targets is now a relatively mature field. Any synthesis that bucks these trends grabs attention, with a recent publication of dictyosphaeric acid A by Richard Taylor's team at the University of York, UK, a case in point. |
