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Chemistry World
September 2009
Paul Docherty |
Column: Totally Synthetic Maduropeptin chromophore (the active component of a chromopore-protein complex, noted as for its potent antitumor and antibiotic activity) is built of two distinct domains   |
Chemistry World
July 30, 2014 |
Psylloborine A It's a somewhat surprising assertion that almost a fifth of natural products are thought to include a dimerization step somewhere in their biosynthesis. |
Chemistry World
June 27, 2013
Paul Docherty |
Bolivianine The still-growing and insanely diverse class of terpene natural products is probably responsible for a considerable number of undergraduate headaches. |
Chemistry World
January 2, 2013
Paul Docherty |
Flueggine A One of the most prolific sources of biologically active natural products is traditional medicines -- whose active components can be exceptionally potent. The Euphorbiaceae family of plants is a productive source of medicinal targets, including the Securinega alkaloids. |
Chemistry World
March 22, 2013
Paul Docherty |
Acutumine A burgeoning class of natural products has been found to restrain the immune system. Acutumine is a relatively recent addition to this collection, even though it was first isolated in the 1920s. The potential of these targets has not gone unnoticed in the synthetic community. |
Chemistry World
September 2, 2013
Paul Docherty |
Steviol A discussion is presented on new ways to synthesize the diterpenoid steviol. |
Chemistry World
May 8, 2014 |
Mandelalide A The recent synthesis of the proposed structure of mandelalide A is a good example of a well-designed route that seamlessly integrates some cutting-edge chemistry. |
Chemistry World
August 2008
Paul Docherty |
Column: Totally Synthetic Impersonating nature isn't easy, and biomimetic syntheses are remarkable in two senses. |
Chemistry World
January 24, 2013
Paul Docherty |
Hyperforin Studies of St John's wort have found several biologically active ingredients, but the primary agent is hyperforin, a potent inhibitor of several neurotransmitters. |
Chemistry World
October 11, 2012
Ian Le Guillou |
Turbo-charged Diels-Alder reaction The Diels - Alder reaction is one that sticks in the mind of even the most reluctant chemistry student -- there is a certain elegance in the ring formation from an alkene and diene. |
Chemistry World
August 22, 2014
Derek Lowe |
Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today. |
Chemistry World
October 2011
Paul Docherty |
Column: Totally Synthetic Antioxidants are not only found in human cells, but also in bacterial cell walls - and a good example is synechoxanthin. |
