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Chemistry World
November 2009
Derek Lowe |
Column: In the pipeline The author advises opening your mind during the screening cascade taken by potential drug targets, and remaining goal orientated at all times   |
Chemistry World
April 6, 2010
Phillip Broadwith |
Rousing sleeping sickness research An orally available drug for African sleeping sickness could be on the horizon, say UK scientists who believe that such a drug would improve the lives of more than 50,000 people who are afflicted with the disease. |
Chemistry World
February 22, 2011
Amaya Camara-Campos |
Repairing faulty genes Israeli scientists have developed compounds that could be better treatments for genetic diseases than current drugs. |
Chemistry World
February 15, 2006
Simon Hadlington |
Pharmaceutical Promise in the Desert Two molecules that inhibit a protein linked to cancer pathogenesis have been discovered in the Arizona desert. |
American Family Physician
March 15, 2004
William H. Markle |
Cutaneous Leishmaniasis: Recognition and Treatment Cutaneous leishmaniasis is a parasitic disease occurring throughout the Americas from Texas to Argentina, and in the Old World, particularly the Middle East and North Africa. It is spread by the female sandfly. |
Chemistry World
July 26, 2012
Derek Lowe |
Screen shots You might not think that the makeup of a compound screening collection could set off many arguments, but there are a few issues there that will do the trick almost every time. |
Chemistry World
August 2009
Derek Lowe |
Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder |
Chemistry World
April 2011 |
Column: In the Pipeline If you look over the whole pharmacopeia, you'll see there are a lot of compounds that got their start as natural products. |
Pharmaceutical Executive
February 1, 2006
Ron Feemster |
Gene Logic: Rescue Squad One or two late-stage clinical failures can land promising drug candidates on the shelf. Forever? Maybe not. Gene Logic tests Big Pharma's dead drugs for hundreds of different targets. |
Chemistry World
March 9, 2011
Simon Hadlington |
Chemical mystery of antifungal compound solved US researchers have applied synthetic organic chemistry to crack a mystery that has baffled scientists for more than 50 years: how the powerful, naturally occurring antifungal compound amphotericin B interacts with sterols in cell membranes. |
Chemistry World
January 3, 2012
Simon Hadlington |
One-pot synthesis creates anticancer candidates Researchers in Germany have developed a simple, rapid and high-yielding cascade synthesis of a collection of polycyclic compounds that resemble indole alkaloid natural products and which interfere with cell division. |
Chemistry World
July 8, 2008
Hayley Birch |
Yellow Fever Mosquito Takes Chemical Cues From Bacteria Bacterial chemicals that encourage female mosquitoes to lay eggs could help to stem the spread of mosquito-borne diseases like dengue and yellow fever, according to US scientists. |
The Motley Fool
August 8, 2007
Brian Lawler |
Array's Bright Pipeline Array BioPharma announces its goals for the months ahead in its fourth-quarter results. What is interesting is the varied mix of new compounds in their pipeline. |
Chemistry World
November 13, 2012
Rachel Cooper |
Detecting cancer cells and parasites Scientists in Denmark have designed a new sensor to detect cells that over-express folate receptors, including cancer cells. The sensor consists of an electrochemical platform composed of graphene and peptide nanotubes with folic acid. |
American Family Physician
June 15, 2006 |
Hepatitis A: What You Should Know A patient guide: What is hepatitis A?... How is the disease spread?... How can I tell if I have the disease?... How is this disease treated?... How long will I be contagious?... etc. |
Managed Care
March 2000
Steve Heimoff |
Getting Out From Under Drug Companies' Shadows The perception that disease management is merely a drug marketing tool seems finally to have vanished from this healthy, though fragmented, industry. |
Chemistry World
April 2009
Derek Lowe |
Column: In the pipeline The author considers the problems of addressing drug development out of sequence |
Chemistry World
January 2012 |
Column: In the pipeline Derek Lowe discusses how companies are increasingly trying to do more with the compounds they already know a lot about |
Chemistry World
October 2008
Derek Lowe |
Column: In the pipeline The author seeks a cure for 'compound bloat' |
AskMen.com
Jacob Franek |
Alzheimer's Disease 101 It's only in the last decade or so that we have truly come to understand the various disorders of the brain that are associated with age and, in most cases, Alzheimer's disease is the prime suspect. Read on for some basic information. |
American Family Physician
February 1, 2005 |
Inflammatory Bowel Disease A patient handout on the intestinal disease, its causes, diagnosis and treatment options. |
Fast Company
Christina Farr |
AHA, Alphabet Set Aside $75 Million To Cure Coronary Heart Disease The American Heart Association, Verily (the company formerly known as Google Life Sciences), and European pharmaceutical giant AstraZeneca are investing the funds over a five-year period. |
