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American Family Physician November 15, 2000 Sharon Scott Morey	Practice Guidelines Guidelines on Migraine: Part 4. General Principles of Preventive Therapy
American Family Physician January 1, 2006 MODI Lowder	Medications for Migraine Prophylaxis Sufficient evidence and consensus exist to recommend propranolol, timolol, amitriptyline, divalproex, sodium valproate, and topiramate as first-line agents for migraine prevention.
American Family Physician November 1, 2000 Sharon Scott Morey	Guidelines on Migraine: Recommendations for Individual Drugs The following is an excerpt of the section in the migraine guidelines that outlines the findings from clinical studies and the specific recommendations for individual drugs...
American Family Physician October 15, 2000 Sharon Scott Morey	Practice Guidelines Guidelines on Migraine: Part 2. General Principles of Drug Therapy...
Nurse Practitioner September 2010 Moloney & Cranwell-Bruce	Pharmacological Management of Migraine Headaches Migraine is one of the top 20 causes of disability worldwide, occurring in 17.6% of women and 5.7% of men
American Family Physician December 1, 2002 Aukerman et al.	Management of the Acute Migraine Headache As many as 30 million Americans have migraine headaches. The impact on patients and their families can be tremendous, and treatment of migraines can present diagnostic and therapeutic challenges for family physicians.
American Family Physician October 15, 2005 Huntington & Yuan	Topiramate (Topamax) for Migraine Prevention Topiramate is more effective than placebo for migraine prevention. Its effectiveness appears to be similar to that of other antiepileptic drugs and beta blockers.
American Family Physician August 1, 2003 Stone et al.	Off-Label Applications for SSRIs Clinical experience supported by ongoing research continues to expand on the broad array of therapeutic applications for this class of medication.
American Family Physician April 15, 2003 Dickerson et al.	Premenstrual Syndrome Premenstrual syndrome, a common cyclic disorder of young and middle-aged women, is characterized by emotional and physical symptoms that consistently occur during the luteal phase of the menstrual cycle.
American Family Physician October 1, 2000 Sharon Scott Morey	Practice Guidelines Headache Consortium Releases Guidelines for Use of CT or MRI in Migraine Work-up...
American Family Physician February 1, 2005 Maizels & McCarberg	Antidepressants and Antiepileptic Drugs for Chronic Non-Cancer Pain The development of newer classes of antidepressants and second-generation antiepileptic drugs has created unprecedented opportunities for the treatment of chronic pain. These drugs modulate pain transmission by interacting with specific neurotransmitters and ion channels.
American Family Physician January 15, 2003 Ables & Baughman	Antidepressants: Update on New Agents and Indications Many antidepressants have been released in the United States over the past two decades. This article is an update of information about the newer agents for depression and new indications for older antidepressants.
American Family Physician February 15, 2005 Beck, Sieber & Trejo	Management of Cluster Headache Cluster headache, an excruciating, unilateral headache usually accompanied by conjunctival injection and lacrimation, can occur episodically or chronically, and can be difficult to treat.
American Family Physician December 15, 2004 Morris Maizels	The Patient with Daily Headaches Although the condition is challenging, appropriate treatment of patients with chronic daily headaches (CDH) can bring about significant improvement in the patient's quality-of-life.
American Family Physician February 15, 2002 Donald W. Lewis	Headaches in Children and Adolescents Headaches are common during childhood and become more common and increase in frequency during adolescence. The rational, cost-effective evaluation of children with headache begins with a careful history...
American Family Physician March 1, 2005 Carolyn J. Sachs	Oral Analgesics for Acute Nonspecific Pain Direct comparative studies of acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) have shown that NSAIDs are more effective than acetaminophen in some situations, but provide equivalent analgesia in others.
Nursing February 2010 Daniel A. Hussar	New Drugs 2010, PART 1 In this article, you'll learn about 16 new drugs.
American Family Physician February 1, 2006 Dana G. Carroll	Nonhormonal Therapies for Hot Flashes in Menopause Hot flash symptoms can significantly impact a woman's quality of life and should be addressed. Severity of the hot flashes, medical history, and concomitant medications should be considered in determining the best therapy for each patient.
Nursing June 2011 Daniel A. Hussar	New Drugs 2011: Part 2 In this article, you'll learn about seven recently approved drugs, including: fingolimod hydrochloride, an oral drug indicated to treat patients with relapsing forms of multiple sclerosis.
American Family Physician September 1, 2002 Millea et al.	Tension-Type Headache Tension-type headache, formerly called tension headache or muscle contraction headache, is a common condition usually self-treated with over-the-counter analgesics. Primary headache is treated symptomatically, with the goal being relief and preventing recurrence.
American Family Physician November 1, 2005 Steven H. Williams	Medications for Treating Alcohol Dependence Medications for treating alcohol dependence primarily have been adjunctive interventions, and only three medications -- disulfiram, naltrexone, and acamprosate -- are approved for this indication by the U.S. Food and Drug Administration.
American Family Physician September 15, 2005 Bonakdar & Guarneri	Coenzyme Q10 This is a safe but expensive supplement with preliminary benefit in neurology, including Parkinson's disease, and inconsistent results in cardiovascular disease requiring further long-term research.
American Family Physician December 15, 2006 Epstein et al.	Newer Agents for the Management of Overactive Bladder The availability of three newer anticholinergic drugs increases the pharmacologic armamentarium for the treatment of overactive bladder. Caution is required with each of these agents, particularly in patients with contraindications to anticholinergic therapy.
American Family Physician September 15, 2001	Guideline for the Management of Heart Failure Caused by Systolic Dysfunction: Part II. Treatment Treatment recommendations for patients with left ventricular systolic dysfunction...
Nursing June 2010 Daniel A. Hussar	New drugs 2010, part 2 In this article, you'll learn about 14 recently marketed new drugs.
Nursing March 2012 Daniel A. Hussar	New Drugs 2012: part I In this article, you'll learn about 11 recently approved drugs.
Nurse Practitioner February 2011 Jennifer M. Belavic	Annual Drug Update: 2010 in Review In 2010, the FDA approved several new drugs and new indications for use in primary care. From new therapies for adults with rheumatoid arthritis to a combination drug for benign prostatic hyperplasia, NPs need to be aware of the latest medications now available.
American Family Physician June 15, 2002 Jeffrey L. Cummings	Guidelines for Managing Alzheimer's Disease: Part II. Treatment Once the clinical diagnosis of Alzheimer's disease has been made, a treatment plan must be developed. Patient symptoms and care needs change as Alzheimer's disease progresses.
American Family Physician October 15, 2002 Zamorski & Albucher	What to Do When SSRIs Fail: Eight Strategies for Optimizing Treatment of Panic Disorder Effective management of panic disorder is a common challenge for family physicians. Selective serotonin reuptake inhibitors (SSRIs) are the drugs of choice for this condition because of their safety and efficacy. But not all patients have a favorable response to SSRI therapy.
American Family Physician October 1, 2002 Bhatia & Bhatia	Diagnosis and Treatment of Premenstrual Dysphoric Disorder From 2 to 10 percent of women of reproductive age have severe distress and dysfunction caused by premenstrual dysphoric disorder, a severe form of premenstrual syndrome. Current research implicates mechanisms of serotonin as relevant to etiology and treatment.
American Family Physician October 15, 2001 Katherine L. Margo	Spironolactone in Left-Sided Heart Failure: How Does It Fit In? The familiar diuretic spironolactone has taken on new life as a treatment for left-sided congestive heart failure. More research is necessary to determine the order and combinations of spironolactone and other medications in slowing the progression of this disease...
American Family Physician May 15, 2004 Birrer & Vemuri	Depression in Later Life: A Diagnostic and Therapeutic Challenge Depression in elderly persons is widespread, often undiagnosed, and usually untreated. Because there is no reliable diagnostic test, a careful clinical evaluation is essential.
Nursing February 2009 Daniel A. Hussar	New Drugs 09: Part 1 Learn about 10 new drugs, including nebivolol HCl, the newest beta-adrenergic blocking agent for hypertension.
American Family Physician December 15, 2005 Hadley & Gaarder	Treatment of Irritable Bowel Syndrome Irritable bowel syndrome affects 10% to 15% of the U.S. population to some degree. Diagnosis is based on clinical signs and symptoms that include abdominal pain, bloating, constipation, and diarrhea.
American Family Physician October 15, 2006 Sharonne N. Hayes	Preventing Cardiovascular Disease in Women The American Heart Association guidelines for cardiovascular disease prevention in women provide physicians with a clear plan for assessment and treatment of cardiovascular disease risk and personalization of treatment recommendations.
American Family Physician December 1, 2000 Norman J. Montalto	Updated Treatment for Influenza A and B The prevention of influenza is best accomplished with a broad-based immunization program...
American Family Physician August 1, 2002 Daphne P. Bicket	Using ACE Inhibitors Appropriately Although angiotensin-converting enzyme (ACE) inhibitors have documented clinical benefits in a variety of clinical situations, the disparity between the evidence from clinical trials and bedside medicine is well documented.
Nurse Practitioner February 2012 Jennifer M. Belavic	Annual drug update 2011 in review Many new medications were approved throughout 2011. This article will cover a variety of drugs that will be useful in nurse practitioner practice
American Family Physician October 15, 2000 Patricia A. Howard & Edward F. Ellerbeck	Optimizing Beta-Blocker Use After Myocardial Infarction Although beta-adrenergic blockers can significantly reduce mortality after a myocardial infarction, these agents are prescribed to only a minority of patients...
American Family Physician December 1, 2000 William E. Chavey	The Importance of Beta Blockers in the Treatment of Heart Failure Traditionally, beta blockers have been considered to be contraindicated in patients with heart failure. Recently, however, several large randomized, controlled mortality trials have been stopped early because of the effects of beta blockers...
American Family Physician November 15, 2004 Peter A. Calabresi	Diagnosis and Management of Multiple Sclerosis The diagnosis of multiple sclerosis should be made by a physician with experience in identifying the disease. Five disease-modifying treatments for multiple sclerosis have been approved by the U.S. Food and Drug Administration.
American Family Physician December 1, 2004 McConaghy & Smith	Outpatient Treatment of Systolic Heart Failure Optimal outpatient treatment of systolic heart failure has three goals that should be pursued simultaneously: (1) control of risk factors for the development and progression of heart failure, (2) treatment of heart failure, and (3) education of patients.
American Family Physician February 15, 2006 Rayner et al.	Behavior Disorders of Dementia: Recognition and Treatment Psychosis may pose a greater challenge than cognitive decline for patients with dementia and their caregivers. Goals of treatment should include symptom reduction and preservation of quality of life.
American Family Physician November 15, 2002 Cynthia M. Williams	Using Medications Appropriately in Older Adults Finding the right balance between too few and too many drugs will help ensure increased longevity, improved overall health, and enhanced functioning and quality of life for the aging population.
American Family Physician March 1, 2004 Zachary A. Flake	Practical Selection of Antiemetics An understanding of the pathophysiology of nausea and the mechanisms of antiemetics can help family physicians improve the cost-effectiveness and efficacy of therapy.
American Family Physician October 15, 2006 Swegle & Logemann	Management of Common Opioid-Induced Adverse Effects Opioids are useful agents for managing acute and chronic pain. When prescribing these medications, an understanding of the risks and benefits is essential.
American Family Physician July 15, 2002 Bruce T. Vanderhoff & Rundsarah M. Tahboub	Proton Pump Inhibitors: An Update Proton pump inhibitors (PPIs) are one of the most commonly prescribed classes of medications in the primary care setting and are considered a major advance in the treatment of acid-peptic diseases.
American Family Physician November 15, 2003 Jones et al.	Common Problems in Patients Recovering from Chemical Dependency This article describes how to care for patients recovering from chemical dependency, including special concerns that arise during the treatment of common medical conditions, to avoid adverse outcomes or relapse into addiction.
Nurse Practitioner February 2012 Wood & Gordon	Preventing CVD in women: The NP's role This article focuses on the new American Heart Association guidelines for preventing cardiovascular disease in women and the nurse practitioner's role in implementing them.
American Family Physician December 1, 2005 Potter, Rindfleisch & Kraus	Management of Active Tuberculosis Although the overall incidence of tuberculosis has been declining in the United States, it remains an important public health concern. Patients who present with symptoms of active tuberculosis (e.g., cough, weight loss, or malaise with known exposure to the disease) should be evaluated.