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Reactive Reports Issue 30 David Bradley |
Marine bugs make drugs William Fenical of the Scripps Institution in La Jolla and his colleagues have discovered a new source of potential drugs -- actinomycetes living in tropical and subtropical ocean sediments. Like their soil-dwelling cousins, the marine actinomycetes produce highly active substances. |
Chemistry World January 6, 2011 Laura Howes |
Using HIV against itself US researchers have developed a 'Trojan horse' molecule that uses HIV to trigger the release of a drug that destroys the virus. |
Chemistry World August 15, 2012 |
The latent threat of tuberculosis Although TB was close to being eradicated in the developed world, it is a major problem in developing countries. With drug-resistant strains on the increase, Clare Sansom outlines the latest in the fight against this killer disease |
HHMI Bulletin Feb 2012 Nancy Ross-Flanigan |
A Safer Shot at TB While trying to understand tuberculosis bacteria genes, researchers discovered a safe way to shut down the bacteria. |
Bio-IT World January 21, 2005 Mark D. Uehling |
How to Find a New TB Drug Scientists at Johnson & Johnson (JNJ) have announced the first novel class of antibiotics in 40 years. The diarylquinolines, as the new compounds will be known, could offer shorter treatment regimens and be a precise weapon against tuberculosis. |
Chemistry World August 24, 2006 Jessica Ebert |
Alzheimer's Researchers Tackle Waste Disposal The memory of mice with Alzheimer's-like symptoms is improved by inoculating the mice with an enzyme involved in protein degradation, report US researchers. The work could lead to new therapies for patients with Alzheimer's disease. |
Chemistry World March 6, 2011 Laura Howes |
Sensitive TB diagnosis using sugar For the first time, tuberculosis can be detected and tracked through the body, using a simple sugar based molecule. |
Science News October 14, 2006 Ivars Peterson |
Knots in Proteins Knotted proteins are rare, but more than just random occurrences. The secret of spontaneous knotting lies in the mathematics of self-avoiding random walks. |
Chemistry World August 22, 2012 Alisa Becker |
Trojan horse tuberculosis treatment The emergence of drug resistant bacterial strains has led to an urgent need for new antibiotic agents. Scientists in the US are utilizing the iron uptake pathway of Mycobacterium tuberculosis as a 'Trojan horse' approach to tuberculosis treatment. |
American Family Physician March 15, 2004 |
Clinical Inquiries Does Screening for Tuberculosis in Children Decrease Morbidity or Mortality? |