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Chemistry World June 2008 Philip Ball	The Crucible By investigating how far a carbon vertex can be bent before it spontaneously flies apart, chemists can gain some understanding of the parameters within which such frameworks must operate.
Chemistry World February 21, 2007 Tom Westgate	Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules.
Chemistry World September 24, 2009 Phillip Broadwith	Carbon can't but tin can US chemists have discovered that distannynes - tin-based analogues of acetylenes - can react reversibly with ethene to make cyclic complexes.
Chemistry World November 3, 2008 Simon Hadlington	Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple?
Chemistry World November 1, 2007 Richard Van Noorden	Step Change for Organic Synthesis US chemists discovered how to attack a complex molecule's unreactive carbon-hydrogen bonds, without resorting to wasteful synthetic aids like protecting and directing groups.
Chemistry World July 13, 2015 Philip Ball	First snapshot of elusive intermediate supplies surprise A team near Zurich in Switzerland, has been able to take a single-molecule snapshot of an intermediate in a common class of organic reactions.
Chemistry World May 29, 2015 Derek Lowe	Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways.
Chemistry World March 9, 2006 Katharine Sanderson	Covalent Bonds Crack Under the Strain Chemists must consider engineering principles when designing molecules following news that tough carbon-to-carbon bonds break easily under mechanical strain.
Chemistry World November 28, 2013	Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity.
Chemistry World November 5, 2007 Ned Stafford	Joining up Nanocircuits A team of scientists have covalently bonded strings of porphyrin molecules on a gold surface -- a step forward in the quest to develop nano-electronics.
Chemistry World September 14, 2011 Simon Hadlington	World's Longest Carbon-Carbon Bond Created Harnessing both attractive and repulsive forces enabled chemists to make a carbon-carbon bond 30 per cent long than normal.
Chemistry World July 31, 2008	Nanostructures Made Easy Scotland-based chemists have invented a new way to build nanoscale arrays of molecules over a large surface area: a technique that may be key to making nanostructures in sophisticated sensors, catalysts, and tiny computer parts.
Chemistry World March 2012	Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug
Chemistry World April 13, 2006 Jon Evans	Chemists Bring Alien Molecule Down to Earth Chemists have recreated an alien molecule in the laboratory by synthesising a stable version of the carbene cyclopropenylidene. Cyclopropenylidene was first detected by radio astronomers in 1985, and is now the most abundant cyclic hydrocarbon observed in interstellar space.
Technology Research News June 29, 2005	Self-assembly: the natural way to make things In biology, there are a few different ways DNA molecules can be replicated and combined.
Chemistry World January 19, 2010 Simon Hadlington	New 'click' reaction to modify proteins Chemists in the US have discovered a new way to attach small molecules to proteins and peptides under mild, aqueous reaction conditions.
Chemistry World June 2008 Sarah Houlton	Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success
Chemistry World December 9, 2013 Jessica Cocker	Hydrogen breaks strong bonds with brute force A method developed by Leo Lau of Western University in Canada and colleagues can break C -- H bonds without damaging the rest of the molecule.
Chemistry World February 27, 2009 Hayley Birch	More data from mixtures via NMR Finnish scientists have developed a new technique for separating out the NMR spectra of compounds in a mixture.
Chemistry World July 9, 2012 Phillip Broadwith	'Molecular cobra' turns C-H to C=C A reagent developed by US chemists can selectively introduce synthetically useful C=C double bonds into unactivated carbon chains, guided by an activating group attached to a nearby oxygen or nitrogen atom.
Chemistry World March 31, 2009 Lewis Brindley	Giving molecules a stretch A simple way to stretch small molecules and measure the forces at play has been developed by researchers in the US.
Wired Erin Biba	Molecular Frameworks, the Building Blocks of All Life The world is complicated, but not as complicated as you might think. Most organic molecules derive from a few relatively simple architectures.
Chemistry World May 16, 2006 Jon Evans	Buckyballs Worth Their Weight in Gold A team of chemists and physicists has uncovered evidence for the existence of hollow buckyball-like cages made of gold.
Reactive Reports David Bradley	Subjective Suboxide Carbon monoxide and carbon dioxide are probably the best known molecules containing just carbon and oxygen, but they do form others, such as carbon suboxide (C3O2), which is one of the most stable.
Chemistry World August 30, 2007 James Mitchell Crow	Toxins' Synthesis Secret Cracked US chemists have discovered that using water instead of organic solvents is the key to understanding how algae make toxins called ladder polyethers.
Chemistry World March 21, 2007 Alison Stoddart	Synthesis Strategy Offers no Protection A radically different approach to constructing complex molecules could help to tap the pharmaceutical potential of natural products.
Chemistry World October 28, 2015 Philip Ball	Speaking of chemistry There were some inevitable names among the candidates for Chemistry World's 'quotable chemistry' competition, including that of Richard Feynman, a less predictable candidate.
Chemistry World September 20, 2012 Jon Evans	World's smallest ice cube created Ice crystals must contain at least 275 water molecules, say German chemists. This size limit has implications for any process that involves ice particles, from cloud formation to making the perfect gin and tonic.
Chemistry World May 31, 2009 Nina Notman	The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used.
Chemistry World May 22, 2008 Richard Van Noorden	Xenon doubled up with water Creating a water molecule with two noble gas atoms interpolated into its structure sounds an improbable feat, but a international team of researchers now claim to have trapped just such an exotic compound in xenon.
Reactive Reports Issue 63 David Bradley	Natural Copy Cat While plants convert carbon dioxide into sugar and oxygen, chemists are having a more difficult time finding an efficient method for converting carbon dioxide into useful fuels.
Chemistry World July 19, 2010 Phillip Broadwith	Designing porous patterns Belgian chemists are finally getting to grips with how to control the way molecules arrange themselves at the solid-liquid interface.
Chemistry World May 30, 2012 Jon Cartwright	Tiny buckyball grown around metal atom An international team of researchers has observed the smallest fullerene to form spontaneously to date using metal atoms for stabilization.
Chemistry World March 3, 2010 Jon Cartwright	Hydrocarbon turns superconductor Researchers in Japan have created the first superconducting material based on a molecule of carbon and hydrogen atoms.
Chemistry World October 29, 2014	Lycopodium alkaloids Not all natural products are created equal. A glance at the total synthesis literature from the past decade is enough to discover that some molecules attract a lot more attention than others.
Chemistry World November 24, 2011 Phillip Broadwith	Rewriting the rules for polar molecules A molecule containing two atoms of the same element can have a permanent electric dipole, say US and German scientists, contradicting the traditional view of molecular polarity.
Technology Research News March 23, 2005	Nanowires track molecular activity Researchers from Harvard University have found a way to use transistors made from silicon nanowires to gain information about how small molecules bind to proteins.
Chemistry World November 2010	Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize.
Chemistry World September 24, 2014 Hayley Simon	Water provides new angle on single molecule imaging Small variations in a molecule's conformation can have a large effect on chemical reactivity. Being able to identify these differences is one of the aims of high resolution spectroscopy.
Chemistry World August 1, 2010 Mike Brown	Snapshots of mystery molecular structures Researchers have used atomic force microscopy to produce clear molecular images that can help determine the correct atomic structure of unknown organic molecules.
Chemistry World October 27, 2006 Richard Van Noorden	Synthetic Origami Folds Like Natural Enzymes Researchers have synthesised a large organic molecule that folds up like a small protein, though its backbone is entirely non-biological. The achievement is a step along the path to producing truly synthetic enzymes in the laboratory.
Technology Research News June 2, 2004	Buckyballs Gain Smaller Kin Researchers from Xiamen University and the Chinese Academy of Sciences have constructed a smaller version of the buckyball or C60 fullerene molecule, a spherical cage of carbon atoms.
Chemistry World June 12, 2013 Kirsty Muirhead	An end to chasing molecules that were never there? Ariel Sarotti from the Rosario National University, Argentina, has developed a new, computationally inexpensive method combining calculated and experimental 13C NMR data to flag up incorrect structures.
Chemistry World March 9, 2007 Michael Gross	Nanowires go Round the Bend Chemists have bent an apparently linear molecular wire into a closed circle, creating a conducting ring just 3 nanometers across.
Chemistry World October 2009	Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions
Chemistry World July 14, 2011 Simon Hadlington	Natural Products Made Via a Single Parent Molecule Chemists in the US have taken inspiration from nature to devise a new concept for rapidly and efficiently synthesising structurally diverse natural products from a single common precursor.
Chemistry World June 5, 2006 Simon Hadlington	The Attraction of Gold for Gold Researchers are unravelling some of the fundamental chemistry surrounding a key but poorly understood aspect of the coordination chemistry of gold -- the weak `aurophilic' interactions between adjacent atoms of Au(I) in organic complexes.
Chemistry World October 12, 2011 Joanne Thomson	Hot Chemistry Temperature played a crucial role in David MacMillan's decision to study chemistry.
Reactive Reports September 2007 David Bradley	Insecticidal Synthesis The efforts of 40 PhD chemistry students and many others have found a way to construct azadirachtin -- a natural insecticide from the neem tree -- in a total synthesis of 64 individual chemical reaction steps.
Chemistry World July 3, 2014 Tami Spector	Of atoms and aesthetics Molecular aesthetics means many things to a few people. For some it means tangible aspects of compounds; for others yet, the ways that chemists represent molecules.