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Chemistry World
March 21, 2013
Phillip Broadwith
AstraZeneca partners with Moderna for $240 million Moderna has developed a way to use messenger RNA (mRNA), the molecule cells use to turn DNA into proteins, to stimulate the production of specific proteins in cells where disease has diminished or eliminated their ability to do so. mark for My Articles similar articles
Chemistry World
May 12, 2008
Simon Hadlington
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. mark for My Articles similar articles
Managed Care
November 2003
Thomas Morrow
Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings. mark for My Articles similar articles
Chemistry World
October 20, 2008
Hayley Birch
RNA computers built in yeast US scientists have assembled ribonucleic acids into an adaptable logic system that can be programmed to sense and respond to molecules inside living yeast cells. mark for My Articles similar articles
HHMI Bulletin
Fall 2012
Ingfei Chen
Same But Not Equal A code within the genetic code explains why identical proteins are produced at varying speeds. mark for My Articles similar articles
HHMI Bulletin
Winter 2013
Sarah C.P. Williams
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. mark for My Articles similar articles
HHMI Bulletin
Winter 2013
Megan Scudellari
Tunneling Out A research team including HHMI investigator Melissa Moore at the University of Massachusetts Medical School has discovered an alternative passageway used by RNA -- protein complexes to exit the nucleus. mark for My Articles similar articles
IEEE Spectrum
March 2011
Lucks & Arkin
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering mark for My Articles similar articles
Chemistry World
October 4, 2006
Bea Perks
Good Year for RNA Roger Kornberg, professor of structural biology at Stanford University, has been awarded the 2006 Nobel prize in chemistry for his work on the molecular basis of transcription. mark for My Articles similar articles
Scientific American
June 2005
JR Minkel
RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right. mark for My Articles similar articles
Chemistry World
August 7, 2008
Simon Hadlington
RNA stops HIV in its tracks Scientists have successfully used a biochemical Trojan horse to smuggle killer sequences of RNA into immune cells to mug invading HIV, stopping infection in its tracks mark for My Articles similar articles
Chemistry World
November 27, 2007
James Mitchell Crow
A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells. mark for My Articles similar articles
Chemistry World
February 12, 2014
Manisha Lalloo
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. mark for My Articles similar articles
HHMI Bulletin
Aug 2011
Cassandra Willyard
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. mark for My Articles similar articles
Chemistry World
March 21, 2010
Simon Hadlington
Nanoparticles successfully deliver RNA interference in cancer patients The system aims to exploit the phenomenon of RNA interference, where short sequences of double-stranded RNA, called small interfering RNA or siRNA, can trigger the disruption of the manufacture of certain proteins in a cell. mark for My Articles similar articles
HHMI Bulletin
February 2012
Sarah C.P. Williams
The Twists and Turns of Immunity Fred Alt has built a career making sense of the immune system -- specifically, the diverse antibodies that fight off invading molecules, from viruses to cancer cells to pollen. mark for My Articles similar articles
Bio-IT World
December 15, 2004
David A. Bumcrot
Identifying RNAi Drug Candidates Breakthroughs in understanding RNA's extensive role in essential cellular processes have opened up the potential for a whole new class of drugs based on RNAi. mark for My Articles similar articles
Technology Research News
June 16, 2004
Genes Automate DNA Machines Researchers have taken a step toward automating nanomachines with a method that allows instructions for a DNA-based machine to be contained in a gene, or another stretch of DNA. mark for My Articles similar articles
Chemistry World
April 28, 2008
Victoria Gill
Gene silencing gets fat A team of researchers in the US has developed fat-like nanoparticles that can carry fragments of RNA into cells, bring treatments based on gene silencing a step closer. mark for My Articles similar articles
Chemistry World
July 17, 2012
Simon Perks
Synthetic nanozymes silence hepatitis C Researchers at the University of Florida, US, have discovered that an artificial nanoparticle complex, known as a nanozyme, can help to treat viral infections by 'shutting off' their genetic material. mark for My Articles similar articles
Chemistry World
March 10, 2008
Simon Hadlington
Cell's Protein Factory Seen in Action Researchers have observed one of nature's most remarkable molecular machines in action. mark for My Articles similar articles
Chemistry World
April 20, 2009
James Urquhart
New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought. mark for My Articles similar articles
Chemistry World
January 11, 2008
John Bonner
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. mark for My Articles similar articles
Wired
April 21, 2008
Rachel Swaby
Chromosome, Proteome ... Decoding the DNA of '-omes' The genome alone can't explain how our bodies work. We need to decode a lot of other complex biological systems that regulate how we develop. mark for My Articles similar articles
Chemistry World
October 2, 2006
Bea Perks
RNAi Pioneers Win Nobel Prize for Medicine Molecular biologists Andrew Fire and Craig Mello have been awarded this year's Nobel prize in physiology or medicine for their discovery of RNA interference. mark for My Articles similar articles
Chemistry World
September 26, 2006
Fiona Case
Synchronised Delivery for DNA and Drugs Polymer capsules that can simultaneously deliver drug molecules and DNA into a cell could boost the power of cancer treatments. mark for My Articles similar articles
Reactive Reports
October 2006
David Bradley
RNA Chemistry Zips Up Nobel Prize If Watson and Crick unlocked the mystery of DNA's structure, then Stanford University's Roger Kornberg and his team unzipped the secret of how the cell converts DNA into the RNA needed to make proteins. mark for My Articles similar articles
HHMI Bulletin
May 2010
Robert Tjian
Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens. mark for My Articles similar articles
Chemistry World
June 9, 2008
Simon Hadlington
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. mark for My Articles similar articles
Technology Research News
May 5, 2004
Kimberly Patch
DNA Bot Targets Cancer Researchers from Israel have constructed a molecular-size computer that is programmed to find signs of cancer cells, and when they are present, dispense DNA molecules designed to eradicate those cells. mark for My Articles similar articles
Prepared Foods
February 2008
Sharon Book
Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage. mark for My Articles similar articles
Pharmaceutical Executive
July 30, 2007
Tomorrow's Drugs A look at the seven top therapies and technologies vying to deliver the next generation of drugs. mark for My Articles similar articles
Chemistry World
February 2012
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball mark for My Articles similar articles
Chemistry World
August 8, 2012
Protein Coat for Gene Therapy Kenneth Woycechowsky's group at the University of Utah has modified a non-viral protein so that it will carry RNA. mark for My Articles similar articles
Chemistry World
January 25, 2010
Hayley Birch
Stabilising RNAs enhances gene silencing in tumours South Korean scientists have found a way to stabilise therapeutic RNA molecules, using chemical modifications, so that they can be more smoothly trafficked into cells. mark for My Articles similar articles
Chemistry World
November 2009
Biology's Nobel molecule factory Three scientists who revealed the structure and workings of the ribosome have shared the 2009 Nobel prize in chemistry. mark for My Articles similar articles
The Motley Fool
July 11, 2007
Brian Orelli
Everybody Loves RNAi Roche is the latest firm to (over)pay for the hottest new drug technology. Alnylam announced that it licensed some of its intellectual property to Roche for $331 million. Investors, take note. mark for My Articles similar articles
Chemistry World
October 7, 2009
Sarah Houlton
Chemistry of life wins Nobel This year's chemistry Nobel prize has been awarded to scientists working on the chemistry of life - the translation of DNA information into proteins by the ribosome. mark for My Articles similar articles
Chemistry World
March 15, 2007
Henry Nicholls
The Mother of All Enzymes Scientists have uncovered the three-dimensional structure of what might be biology's first enzyme. This sheds light on the chemistry at a key moment in the origin of life, they argue. mark for My Articles similar articles
HHMI Bulletin
February 2011
Sarah C.P. Williams
Skin Sense An early question about aging skin led to answers on how cells code for their location. mark for My Articles similar articles
Chemistry World
March 14, 2012
Helen Bache
Diabetes reduces antioxidant benefits Scientists in China have discovered that the blood plasma proteins of type II diabetes patients reduce the beneficial effects of dietary polyphenols. mark for My Articles similar articles
Chemistry World
October 31, 2007
John Bonner
Brain's Wiring Seen in Technicolor Researchers in the US have developed a technique that could allow neurologists to draw a detailed wiring plan of the mammalian brain by inserting genes coding for fluorescent proteins into transgenic mice. mark for My Articles similar articles
Chemistry World
December 19, 2007
Simon Hadlington
Snapshot of Proteins Linked to Autism Researchers in France and the US have caught on camera the gentle embrace between two proteins that sit on either side of the junction between nerve cells. It's this short circuit that has thought to cause some types of autism. mark for My Articles similar articles
The Motley Fool
August 15, 2006
Ralph Casale
Sirna Battles Genes Gone Bad Pharmaceutical start-up Sirna Therapeutics tests drugs to silence rogue genes. Investors, while drugs based on RNA interference may have the potential to become the next big thing in biotechnology, they're still a long, long way from becoming FDA-approved, marketable entities. mark for My Articles similar articles
Chemistry World
September 23, 2009
Simon Hadlington
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. mark for My Articles similar articles
Chemistry World
November 2006
Bea Perks
Call That Chemistry? This year's Nobel prize in chemistry was a tour de force for crystallography, underscoring the vital role chemistry plays across the sciences. mark for My Articles similar articles
Bio-IT World
December 15, 2004
William Marshall
Applications of RNAi RNA interference is a highly coordinated gene regulatory mechanism that appears to be highly conserved across all metazoans studied thus far. mark for My Articles similar articles
HHMI Bulletin
February 2011
Mitzi Baker
When Worlds Collide The right time and place led to a new RNAi-like pathway in bacteria for biochemist Jennifer Doudna and geobiologist Jill Banfield. mark for My Articles similar articles
Bio-IT World
December 10, 2002
Rotem Sorek
Alternative Splicing: Listen to the Mouse The completed mouse genome may help to finally pin down the size of the transcriptome. mark for My Articles similar articles
The Motley Fool
May 25, 2005
Brian Gorman
Another Deal for Isis Investors shouldn't get their hopes up over the drugmaker's latest collaboration. mark for My Articles similar articles