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HHMI Bulletin
Nov 2010 |
New live action microscopy lets scientists follow the first days of a zebrafish embryo's development The promise of live embryo imaging is unquestionable. Light-sheet microscopy will allow scientists for the first time to describe in detail the processes of development in complex vertebrates   |
HHMI Bulletin
Aug 2010
Sarah C.P. Williams |
Fruit Fly Cells Don't All Know What Sex They Are HHMI scientists have now found that many cells in male and female fruit flies not only look the same, they are more identical at a molecular level than was previously thought. |
HHMI Bulletin
Aug 2011
Cassandra Willyard |
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. |
HHMI Bulletin
Fall 2012
R. John Davenport |
Hanchuan Peng: SmartScopes Even when he launched his career as an engineer and computer scientist, Hanchuan Peng was drawn to the beauty of biology. He is a leader in developing sophisticated ways to make sense of biological images. |
Bio-IT World
September 2006
John A. Wass |
Integrating Knowledge The results of new mathematical routines have the potential to save pharmaceuticals millions of dollars in drug development. And yet the flow of successful drugs is dwindling. The problem goes beyond bureaucracy and lies in the complexity of the problem. |
| Chemistry World |
Fishing for Chemical Answers to Biological Questions James K. Chen talks about chemical biology, his love for the outdoors and fly fishing. |
HHMI Bulletin
Aug 2010
Virginia Hughes |
Glimpsing Inside a Moving Fruit Fly's Brain Vivek Jayaraman wants to capture, in real time, how the fly's brain responds to a changing environment. Ultimately, he hopes to uncover very basic patterns -- "algorithms" -- of fly brain activity that hold true in more complex brains including, presumably, ours. |
HHMI Bulletin
Fall 2012
Elise Lamar |
Push and Pull Jennifer Zallen, an HHMI early career scientist at Memorial Sloan-Kettering Cancer Center, studies how embryonic tissues stretch along an anterior-posterior axis using the fruit fly Drosophila melanogaster as a model system. |
Chemistry World
May 17, 2006
Bea Perks |
Biochemists Reveal Hidden Drug Effects Researchers have identified unexpected drug activities by probing biochemical pathways inside living cells. |
Bio-IT World
July 2005
David M. Evans |
Cellular Imaging Takes Drug Discovery to New Heights The potential applications and ultimate value of high-content screening (HCS) and cellular image analysis are limited only by the imagination and expertise of the drug discovery groups using them to probe gene function and cell behavior. |
Bio-IT World
July 11, 2002
Malorye Branca |
Deep Sequence Diving Like sailors of old, genomic data miners dream of discovering riches and fame. Given the recent improvements in analytics -- and a little more time -- they just might succeed. |
Chemistry World
August 29, 2008
John Bonner |
Chip test for IVF embryos US researchers may have found a new way to assess the health of embryos produced by in vitro fertilization, using a lab on a chip approach to measure their uptake of nutrients. |
Bio-IT World
August 15, 2005
Robert M. Frederickson |
What's 'Post' About Postgenomic? Bioinformatics tools can help organize and study genomic sequences that were discovered in the '90s. The tools help with tasks like analyzing gene expression, predicting protein structure and function, and establishing networks of interacting protein in cells. |
Chemistry World
July 31, 2014
Andy Extance |
Turing patterns show their hand in finger formation James Sharpe's team at the Center for Genomic Regulation in Barcelona has identified proteins that create a 'Turing network' that tells embryo limb cells what to become. |
Scientific American
May 2009
Christine Soares |
Cancer Clues from Embryonic Development Rethinking cancer by seeing tumors as a cellular pregnancy. |
HHMI Bulletin
Aug 2011
Janelle Weaver |
Leading a Double Life with CSF Lucky for us, the organs in our bodies come with a self-repair kit. Though regularly bombarded by harmful bacteria, more often than not they manage to heal themselves. How this happens has puzzled scientists, but now there may be some answers. |
Bio-IT World
November 2006
John Russell |
Pathway Pioneers Innovative uses for pathway tools and exciting results from early users are sprouting like mushrooms after a spring rain -- albeit following a few harsh winters. And the usually risk-averse pharmaceutical industry has led in adopting pathway tools. |
HHMI Bulletin
Nov 2010
Sarah C.P. Williams |
Maternal and Paternal Genes Don't Always Have The Same Effect On Offspring The genes you inherited from your mom and those passed along from your dad don't have equal footing when it comes to how they influence your biology. |
Salon.com
May 1, 2000
Arthur Allen |
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. |
Chemistry World
February 2012 |
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball |
Reason
Aug/Sep 2000
Ronald Bailey |
Strands of Life Book Review: Genome: The Autobiography of a Species in 23 Chapters, by Matt Ridley |
Bio-IT World
June 2006
Kevin Davies |
The Data Deluge: Deal or No Deal? Far from decrying the data glut, researchers should embrace the complexity of genomic and other sources of data, particularly for its predictive properties in the field of personalized medicine. |
Salon.com
December 19, 2000
Carolyn McConnell |
"The Century of the Gene" by Evelyn Fox Keller A new book argues that there may be no such thing as a gene. At least, it has proved very difficult to isolate a discrete physical item that can do the work our notion of the gene does... |
Science News
April 22, 2006 |
Finding Form A website devoted to advances in the emerging field of evolutionary developmental biology. Watch brief movies of embryo formation in fruit flies, butterfly wing development, and other natural wonders. |
Chemistry World
February 3, 2015
Jennifer Newton |
Chip-on-a-cell Colleagues at the Institute of Microelectronics Barcelona affixed polysilicon chips, which act as barcodes, onto the outer surface of the zona pellucida, a membrane that surrounds immature egg.cells and embryos. |
Bio-IT World
March 8, 2005
Kevin Davies |
Evolution of New Genes Studied EMBL researchers use comparative genomic analysis to identify new primate-specific gene family. |
Chemistry World
July 2, 2007 |
Why does a fly fly? Chinese scientists have deciphered the complicated value-based decision-making process of the fruit fly. |
Bio-IT World
September 16, 2004
Rabiya S. Tuma |
Blinded by the Light Myriad advances in light microscopy are increasing resolution, accelerating confocality, improving detection -- and toying with the laws of nature. |
Bio-IT World
January 21, 2005
Robert M. Frederickson |
High-Throughput Science Although genomic assays led the charge toward high-throughput science, new detection systems and formats are enabling the application of high-throughput techniques to proteins and cells. |
Popular Mechanics
January 2010
Amber Angelle |
How to Create a Designer Baby Women undergoing in vitro fertilization could one day choose to have a baby boy with perfect vision, an aptitude for sports and a virtual lock on avoiding colon cancer. |
Bio-IT World
August 15, 2005
Salvatore Salamone |
NCI's Focus on Data Analysis A team of scientists developed an automated imaging workflow and analysis process to simplify the use of confocal microscopes, affording researchers a faster way to study details about cancer cells and tissues. |
Salon.com
August 21, 2000
Lori B. Andrews |
Embryos under the knife The latest reproductive technology is just the next step on our sprint toward human cloning. |
Bio-IT World
Dec 2006/Jan 2007
Kevin Davies |
The NextBio Thing in Bioinformatics NextBio, which this fall officially introduced its platform after a year of beta testing by a handful of select organizations, aims to provide high-throughput information to researchers without them having to learn anything. |
Geotimes
October 2006
Kathryn Hansen |
Fossil Embryos Exposed in 3-D For the first time, advanced X-ray imaging technology has captured a 3-D look inside tiny fossil embryos, revealing details that confirm one animal's place on the evolutionary tree. |
