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Chemistry World January 8, 2015 Matthew Gunther	New antibiotic could treat infection while dodging resistance problems A new antibiotic that can kill life-threatening bacteria -- without them appearing to be able to develop resistance to the drug -- has been discovered by a team of scientists.
Chemistry World March 13, 2013 Ned Stafford	Antibiotic resistance is a 'ticking time bomb' Global research efforts to develop new antibiotics need to be accelerated urgently, the UK government's chief medical officer has warned. She adds that that new drugs are desperately needed to fight the 'catastrophic threat' of growing antimicrobial resistance.
Chemistry World February 27, 2013 Anthony King	PharmaSea to scour ocean depths for new drugs A new project will soon see scientists trawling the ocean bottoms for new bioactive compounds. Scientists on the PharmaSea mission will haul samples of mud and sediment from the deep sea, isolating marine organisms in the hunt for novel drug candidates.
Chemistry World December 6, 2013 Julianne Wyrick	Crowdsourcing unearths promising anticancer compound Crowdsourcing soil from across the US turned up some interesting fungi with promising medicinal molecules.
Chemistry World January 30, 2015 Rebecca Trager	Billion dollar package unveiled to fight antibiotic resistance President Obama has made a huge investment in the fight against antibiotic resistant bacteria
Chemistry World April 3, 2008 Philip Ball	Antibiotic-Eating Bacteria Found in Soil Scientists in the US have found that soil is full of bacteria that will feed and grow on antibiotics the very compounds created to kill them.
Chemistry World March 5, 2015 Emma Stoye	Forgotten synthetic PhD theses set to be given new lease of life A team of researchers have amassed a digital collection of more than 75,000 compounds from PhD theses that might otherwise have mouldered in obscurity.
Chemistry World August 6, 2007 Tom Westgate	Unique Antibiotic Beats Superbugs' Resistance The discovery of how a unique antibiotic kills its targets has uncovered a new way to tackle resistant superbugs. A team of chemists and structural biologists have studied how the natural antibiotic lactivicin interacts with a crucial bacterial protein.
Chemistry World April 27, 2011 Carol Stanier	Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life.
Chemistry World December 4, 2009 Lewis Brindley	Potent two-pronged antibiotic provides hope for future drugs A two-headed compound obtained from soil bacteria may hold the key to developing the next generation of antibiotics, researchers in the UK report.
Chemistry World April 4, 2007 John Bonner	Antibiotic Combinations Tackle Resistance Using combinations of certain antimicrobial compounds can favor the growth of non-resistant strains of bacteria at the expense of resistant ones. The surprising finding may provide a general strategy to help eradicate strains of bacteria that are resistant to antibiotic therapy.
Chemistry World July 8, 2014 Anthony King	Call for new models to pay for antibiotics Governments will need to think seriously about changing the way they pay for the drugs. That's the conclusion of a report from the UK House of Commons science and technology committee.
Chemistry World May 29, 2014 Carla Pegoraro	Dual warhead kills and disarms bacteria A compound that kills bacteria and cleaves their DNA to prevent them passing on drug-resistant genes has been designed by researchers in India.
Bio-IT World January 21, 2005 Mark D. Uehling	How to Find a New TB Drug Scientists at Johnson & Johnson (JNJ) have announced the first novel class of antibiotics in 40 years. The diarylquinolines, as the new compounds will be known, could offer shorter treatment regimens and be a precise weapon against tuberculosis.
Chemistry World July 26, 2012 Derek Lowe	Screen shots You might not think that the makeup of a compound screening collection could set off many arguments, but there are a few issues there that will do the trick almost every time.
HHMI Bulletin Nov 2010 Sarah C.P. Williams	A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections.
Chemistry World May 20, 2015 Katrina Kramer	Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs.
Chemistry World May 6, 2014 Andy Extance	WHO raises alarm on deadly bacteria The World Health Organization has warned antibiotic resistant bacteria could bring a nightmarish future, where seemingly trivial scrapes turn lethal, and currently routine operations become too risky to contemplate.
Chemistry World February 5, 2015 Emma Stoye	'Robot scientist' speeds up drug discovery An artificial intelligence system -- or 'robot scientist' -- capable of screening potential drugs almost completely independently could speed up drug development, say the UK researchers who created it.
Chemistry World May 19, 2015 Anthony King	Roadmap to reward pharma for creating new antibiotics unveiled Pharma firms need better incentives to create novel antibiotics to head off an 'apocalyptic scenario' where commonplace infections become deadly once more.
Chemistry World April 24, 2006 Jon Evans	Putting Some Backbone Into Bacterial Killers Chemists developed a novel folded oligomer (foldamer) that is highly effective at puncturing bacteria and could form the basis for a novel class of antibiotics.
Chemistry World September 15, 2013 Andy Extance	Light-switch antibiotics could undermine resistance Dutch chemists have made a new weapon to fight bacteria: an antibiotic whose microbe-killing activity they can turn on using ultraviolet light, before it slowly diminishes.
Chemistry World July 15, 2010 Matt Wilkinson	Biotechs plot path of least resistance Biopharmaceutical companies are moving into antibiotics, and filling the void left by big pharma.
Chemistry World February 12, 2015 Dinsa Sachan	Target ignorance to tackle resistance After the discovery of the New Delhi metallo-beta-lactamase-1 (NDM-1) gene, which renders some bacteria resistant to most antibiotics, India has attracted global criticism for not being able to contain antibiotic resistance.
Chemistry World November 1, 2011 Sarah Houlton	A Shot in the Arm for Drugs for Neglected Diseases A new consortium of public and private sector partners has been launched by the World Intellectual Property Organization. Its aim is to share intellectual property that may help find drugs for malaria, tuberculosis and other neglected tropical diseases.
Chemistry World February 22, 2010 Hayley Birch	Soil switches on antibiotic genes in bacteria So-called 'cryptic' bacterial genes that preside over the production of medically important compounds can be switched on using environmental triggers, German scientists have shown.
BusinessWeek October 29, 2007 Catherine Arnst	Superbugs: Where Are the Wonder Drugs? Antibiotics are losing the battle against superbugs, and drugmakers are slow to replenish the arsenal.
AskMen.com Harold Russell	The Lowdown On Superbugs The overuse and misuse of antibiotics has led to the development of resistant strains of bacteria, commonly referred to as superbugs.
Reactive Reports Issue 73 David Bradley	Gator Aid It's perhaps not the first place you would think to search for superbug-beating antibiotics, but alligator's blood could be a great source of novel compounds that could defeat strains of bacteria resistant to conventional antibiotics.
Chemistry World October 2010	Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery
Chemistry World March 6, 2013 Derek Lowe	New antibiotics: what's the hold up? Money's a factor that could be adjusted by regulatory agencies, governments, and foundations. But no amount of cash will keep resistant bacteria from being the hard targets they are.
Chemistry World December 2008	Column: In the pipeline I've worked on two drug discovery efforts (one right after the other, as fate would have it) whose final compounds differed by essentially one methyl group from the starting points of each project.
Chemistry World October 2008 Derek Lowe	Column: In the pipeline The author seeks a cure for 'compound bloat'
Chemistry World November 30, 2012 Andy Extance	Chemists cull compounds using 'intuition' Medicinal chemists might be using far fewer parameters to choose candidate fragments for a screening collection than they think they do. Their choices can be mimicked based on just one or two properties, a team led by researchers at Swiss-headquarted pharmaceutical firm Novartis has found.
Chemistry World May 31, 2013 Phillip Broadwith	Japanese pharma opens compound vaults Japanese pharmaceutical companies are opening up their libraries of experimental compound as part of a new partnership program. The initiative aims to find new drugs for malaria, tuberculosis and neglected tropical diseases.
Chemistry World September 24, 2013 Jennifer Newton	Plants and microorganisms are the original synthetic chemists Greg Challis is a professor of chemical biology at the University of Warwick in the UK. Research in the Challis group encompasses the discovery, biosynthesis, bioengineering and mechanism of action of bioactive natural products.
Chemistry World October 29, 2013 Harriet Brewerton	Paper device spots antibiotic-resistant bacteria Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas.
Chemistry World November 24, 2015 Anthony King	Poor management of antibiotics squandering life-saving drugs A thriving unregulated online market for antibiotics and poor quality products are two problems that are driving antimicrobial resistance worldwide, according to the Review on Antimicrobial Resistance
Chemistry World August 2009 Derek Lowe	Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder
Chemistry World June 1, 2012 Derek Lowe	Peace, love and understanding You'd think that the chemists and biologists working in drug discovery would understand each other pretty well by now. You would be wrong about that.
Chemistry World August 13, 2015	Exploiting the data mine Chemists must embrace open data to allow us to collectively get the best out of the masses of new knowledge we unearth, reports Clare Sansom
Chemistry World July 1, 2013 James Urquhart	Antibiotic research hits a sweet spot UK researchers have found a way to weaken the molecular armour of Escherichia coli to allow the host's immune system to attack and kill the pathogen.
Pharmaceutical Executive July 30, 2007 Sarah Houlton	Global Report: Make Resistance Futile Patients are losing the battle against bacteria. Can pharma be convinced to swing the sword of new antibiotic development?
Chemistry World July 2010	Supporting science The Wellcome Trust is one of the largest science funding bodies in the world. Sir Mark Walport, the trust's director, tells Phillip Broadwith how it spends its money
Chemistry World March 15, 2012 Andrew Shore	Designer solvent hits hospital superbug Scientists from Ireland, the Czech Republic and Spain have found an antimicrobial ionic liquid that targets MRSA (methicillin-resistant Staphylococcus aureus).
Chemistry World December 9, 2015 Anthony King	Review calls for tighter controls on antibiotic use in farming The Review on Antimicrobial Resistance has labeled antibiotic use in agriculture a critical threat to public health in its latest report and is recommending tighter controls on the practice.
Food Processing March 2009 Diane Toops	Kraft Foods Global Thinks Outside the Box with Bioactive Ingredients Kraft hires a pharmaceutical company to help it develop functional foods.
Chemistry World May 31, 2009 Nina Notman	The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used.
Chemistry World April 25, 2013 Andreas Barth	Chemical bibliometrics Counting compounds instead of publications and citations opens new perspectives for data-based scientific discovery and it can complement and stimulate both experimental and theoretical research.
Chemistry World June 17, 2015 James Urquhart	Promising compound offers single dose knock-out for malaria Ian Gilbert and colleagues, working with the Medicines for Malaria Venture, have found a compound dubbed DDD107498 which kills Plasmodium falciparum -- the species responsible for most dangerous form of malaria.